HUP0303720A2 - Egy immunstimuláns oligonukleotidot és egy tokolt tartalmazó adjuvánskészítmény - Google Patents

Egy immunstimuláns oligonukleotidot és egy tokolt tartalmazó adjuvánskészítmény

Info

Publication number
HUP0303720A2
HUP0303720A2 HU0303720A HUP0303720A HUP0303720A2 HU P0303720 A2 HUP0303720 A2 HU P0303720A2 HU 0303720 A HU0303720 A HU 0303720A HU P0303720 A HUP0303720 A HU P0303720A HU P0303720 A2 HUP0303720 A2 HU P0303720A2
Authority
HU
Hungary
Prior art keywords
subject
tocol
vaccines
adjuvant
adjuvant composition
Prior art date
Application number
HU0303720A
Other languages
English (en)
Inventor
Nathalie Garcon
Catherine Marie Ghislaine Gerard
Jean Stephenne
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of HUP0303720A2 publication Critical patent/HUP0303720A2/hu
Publication of HUP0303720A3 publication Critical patent/HUP0303720A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A találmány tárgyát képezik új adjuvánskészítmények oltóanyagokbanvaló alkalmazásra. A találmány tárgyát képező adjuvánskészítményekkonkrétabban egy immunstimuláns oligonukleotid és egy tokolkombinációját tartalmazzák. A találmány tárgyát képezik továbbáoltóanyagok, amelyek találmány szerinti adjuvánskészítményt éslegalább egy antigént tartalmaznak. A találmány tárgyát képeziktovábbá eljárások a találmány szerinti adjuvánskészítmények ésoltóanyagok előállítására, valamint ezek gyógyszerként történőalkalmazása. A találmány tárgyát képezik továbbá eljárások egybetegségre hajlamos, vagy abban szenvedő egyén kezelésére a találmányszerinti oltóanyagok parenterális vagy nyálkahártyán keresztüliadagolásával. Ó
HU0303720A 2000-10-18 2001-10-16 Adjuvant composition comprising an immunostimulatory oligonucleotide and a tocol HUP0303720A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0025577.8A GB0025577D0 (en) 2000-10-18 2000-10-18 Vaccine
PCT/EP2001/011985 WO2002032454A1 (en) 2000-10-18 2001-10-16 Adjuvant composition comprising an immunostimulatory oligonucleotide and a tocol

Publications (2)

Publication Number Publication Date
HUP0303720A2 true HUP0303720A2 (hu) 2004-03-29
HUP0303720A3 HUP0303720A3 (en) 2004-11-29

Family

ID=9901557

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303720A HUP0303720A3 (en) 2000-10-18 2001-10-16 Adjuvant composition comprising an immunostimulatory oligonucleotide and a tocol

Country Status (21)

Country Link
US (1) US20040047869A1 (hu)
EP (1) EP1326639B1 (hu)
JP (1) JP2004511529A (hu)
KR (1) KR20030044016A (hu)
CN (1) CN100346829C (hu)
AT (1) ATE383872T1 (hu)
AU (2) AU2168902A (hu)
BR (1) BR0114785A (hu)
CA (1) CA2425310A1 (hu)
CZ (1) CZ20031094A3 (hu)
DE (1) DE60132474T2 (hu)
ES (1) ES2299530T3 (hu)
GB (1) GB0025577D0 (hu)
HU (1) HUP0303720A3 (hu)
IL (1) IL155283A0 (hu)
MX (1) MXPA03003406A (hu)
NO (1) NO20031646L (hu)
NZ (1) NZ525321A (hu)
PL (1) PL365322A1 (hu)
WO (1) WO2002032454A1 (hu)
ZA (1) ZA200302887B (hu)

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US6693086B1 (en) * 1998-06-25 2004-02-17 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
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Also Published As

Publication number Publication date
JP2004511529A (ja) 2004-04-15
IL155283A0 (en) 2003-11-23
US20040047869A1 (en) 2004-03-11
BR0114785A (pt) 2003-12-23
AU2002221689B2 (en) 2004-04-01
ATE383872T1 (de) 2008-02-15
HUP0303720A3 (en) 2004-11-29
CZ20031094A3 (cs) 2003-09-17
CN100346829C (zh) 2007-11-07
KR20030044016A (ko) 2003-06-02
CA2425310A1 (en) 2002-04-25
EP1326639A1 (en) 2003-07-16
NO20031646D0 (no) 2003-04-10
PL365322A1 (en) 2004-12-27
GB0025577D0 (en) 2000-12-06
EP1326639B1 (en) 2008-01-16
DE60132474T2 (de) 2009-01-15
AU2168902A (en) 2002-04-29
DE60132474D1 (de) 2008-03-06
MXPA03003406A (es) 2005-01-25
WO2002032454A1 (en) 2002-04-25
CN1481254A (zh) 2004-03-10
NZ525321A (en) 2004-06-25
ZA200302887B (en) 2004-07-12
ES2299530T3 (es) 2008-06-01
NO20031646L (no) 2003-06-14

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