HUP0203972A2 - Antigént és glikolipidet tartalmazó készítmény szublingvális úton történő alkalmazásra - Google Patents
Antigént és glikolipidet tartalmazó készítmény szublingvális úton történő alkalmazásraInfo
- Publication number
- HUP0203972A2 HUP0203972A2 HU0203972A HUP0203972A HUP0203972A2 HU P0203972 A2 HUP0203972 A2 HU P0203972A2 HU 0203972 A HU0203972 A HU 0203972A HU P0203972 A HUP0203972 A HU P0203972A HU P0203972 A2 HUP0203972 A2 HU P0203972A2
- Authority
- HU
- Hungary
- Prior art keywords
- antigen
- composition
- production
- glycolipid adjuvant
- sublingual administration
- Prior art date
Links
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 title abstract 2
- 229930186217 Glycolipid Natural products 0.000 title abstract 2
- 239000002671 adjuvant Substances 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 abstract 4
- 238000004519 manufacturing process Methods 0.000 abstract 3
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000005784 autoimmunity Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 229940021993 prophylactic vaccine Drugs 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 229940021747 therapeutic vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány tárgyát legalább egy antigént és glikolipid-adjuvánsttartalmazó készítmény szublingvális úton történő alkalmazása képezimukozális és szisztémás immunitás kiváltására. A találmány tárgyátképezik továbbá a találmány szerint alkalmazott készítmények,eljárások a találmány szerinti készítmények előállítására, valamint akészítmények alkalmazása fertőzések, autoimmunitás, tumor vagyallergia kezelésére, megelőzésére vagy a felsoroltakkal szembenifogékonyság csökkentésére alkalmas gyógyszerek és az antigéntfelismerő ellenanyagok előállítására. A találmány szerinti megoldásprofilaktikus vagy terápiás vakcinaként alkalmas immunizálásra,allergia kezelésére, vagy ellenanyagok termeltetésére. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0000891.2 | 2000-01-14 | ||
GBGB0000891.2A GB0000891D0 (en) | 2000-01-14 | 2000-01-14 | Formulation |
PCT/GB2001/000142 WO2001051082A1 (en) | 2000-01-14 | 2001-01-15 | Composition of antigen and glycolipid adjuvant sublingual administration |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0203972A2 true HUP0203972A2 (hu) | 2003-03-28 |
HUP0203972A3 HUP0203972A3 (en) | 2011-02-28 |
HU230545B1 HU230545B1 (hu) | 2016-11-28 |
Family
ID=9883730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0203972A HU230545B1 (hu) | 2000-01-14 | 2001-01-15 | Antigént és glikolipidet tartalmazó készítmény szublingvális úton történő alkalmazásra |
Country Status (15)
Country | Link |
---|---|
US (1) | US8470331B2 (hu) |
EP (3) | EP2322212A1 (hu) |
JP (1) | JP4648603B2 (hu) |
AR (1) | AR027924A1 (hu) |
AU (1) | AU2001228625A1 (hu) |
CA (1) | CA2397359C (hu) |
CZ (1) | CZ304941B6 (hu) |
DE (1) | DE60139305D1 (hu) |
DK (1) | DK2100616T3 (hu) |
ES (2) | ES2561360T3 (hu) |
GB (2) | GB0000891D0 (hu) |
HU (1) | HU230545B1 (hu) |
PL (1) | PL356963A1 (hu) |
SK (1) | SK288411B6 (hu) |
WO (1) | WO2001051082A1 (hu) |
Families Citing this family (22)
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US20060052757A1 (en) * | 1996-06-04 | 2006-03-09 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with analgesic or anesthetic |
US20060030826A1 (en) * | 1996-06-04 | 2006-02-09 | Vance Products Incorporated,d/b/a Cook Urological Incorporated | Implantable medical device with anti-neoplastic drug |
US20060025726A1 (en) * | 1996-06-04 | 2006-02-02 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with pharmacologically active layer |
GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
WO2004047793A1 (en) | 2002-11-26 | 2004-06-10 | Alk-Abelló A/S | Pharmaceutical allergen product |
US8012505B2 (en) | 2003-02-28 | 2011-09-06 | Alk-Abello A/S | Dosage form having a saccharide matrix |
WO2005115449A1 (en) * | 2004-05-28 | 2005-12-08 | Alk-Abelló A/S | Method of treating allergy and infection by eliciting an iga antibody response |
ITMI20061117A1 (it) * | 2006-06-09 | 2007-12-10 | Michele Bonanomi | Una composizione farmaceutica per la somministrazione sublinguale di vaccini metodo per la sua preparazione e sui usi |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
CN101516396B (zh) | 2006-09-26 | 2013-10-09 | 传染性疾病研究院 | 包含合成佐剂的疫苗组合物 |
WO2010127144A1 (en) | 2009-04-29 | 2010-11-04 | Muniyappa Pravin K | Device and method for the diagnosis of gastrointestinal allergy |
US8722064B2 (en) | 2009-06-05 | 2014-05-13 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants |
GB201009273D0 (en) * | 2010-06-03 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel vaccine |
EP3632463A1 (en) | 2011-04-08 | 2020-04-08 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
JP5650780B2 (ja) | 2012-04-04 | 2015-01-07 | 日東電工株式会社 | ワクチン組成物 |
NZ701881A (en) | 2012-05-16 | 2016-10-28 | Immune Design Corp | Vaccines for hsv-2 |
EP3711768A1 (en) | 2013-04-18 | 2020-09-23 | Immune Design Corp. | Gla monotherapy for use in cancer treatment |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
WO2017173398A1 (en) | 2016-04-01 | 2017-10-05 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
JP2023518924A (ja) * | 2020-03-24 | 2023-05-09 | チョル アン,ビョン | 幼い哺乳動物の粘膜関連伝染性疾病を予防または治療するための血清組成物の製造方法、前記方法によって製造された血清組成物及びその用途 |
KR102151962B1 (ko) | 2020-03-24 | 2020-09-04 | 안병철 | 어린 포유동물의 전염성 질병을 예방 또는 치료하기 위한 혈청 조성물의 제조방법, 상기 방법에 의해 제조된 혈청 조성물 및 이의 용도 |
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-
2000
- 2000-01-14 GB GBGB0000891.2A patent/GB0000891D0/en active Pending
-
2001
- 2001-01-12 AR ARP010100157A patent/AR027924A1/es unknown
- 2001-01-15 AU AU2001228625A patent/AU2001228625A1/en not_active Abandoned
- 2001-01-15 CZ CZ2002-2417A patent/CZ304941B6/cs not_active IP Right Cessation
- 2001-01-15 PL PL01356963A patent/PL356963A1/xx unknown
- 2001-01-15 WO PCT/GB2001/000142 patent/WO2001051082A1/en active Application Filing
- 2001-01-15 SK SK1041-2002A patent/SK288411B6/sk not_active IP Right Cessation
- 2001-01-15 DK DK09159908.4T patent/DK2100616T3/en active
- 2001-01-15 DE DE60139305T patent/DE60139305D1/de not_active Expired - Lifetime
- 2001-01-15 US US10/181,684 patent/US8470331B2/en active Active
- 2001-01-15 EP EP10011044A patent/EP2322212A1/en not_active Withdrawn
- 2001-01-15 EP EP09159908.4A patent/EP2100616B1/en not_active Expired - Lifetime
- 2001-01-15 ES ES09159908.4T patent/ES2561360T3/es not_active Expired - Lifetime
- 2001-01-15 EP EP01942305.2A patent/EP1255563B2/en not_active Expired - Lifetime
- 2001-01-15 CA CA2397359A patent/CA2397359C/en not_active Expired - Lifetime
- 2001-01-15 GB GB0101035A patent/GB2360210B/en not_active Expired - Lifetime
- 2001-01-15 JP JP2001551505A patent/JP4648603B2/ja not_active Expired - Fee Related
- 2001-01-15 ES ES01942305.2T patent/ES2328336T5/es not_active Expired - Lifetime
- 2001-01-15 HU HU0203972A patent/HU230545B1/hu unknown
Also Published As
Publication number | Publication date |
---|---|
GB0101035D0 (en) | 2001-02-28 |
GB2360210A (en) | 2001-09-19 |
JP2003519669A (ja) | 2003-06-24 |
ES2328336T5 (es) | 2016-06-21 |
EP2100616B1 (en) | 2015-11-25 |
GB2360210B (en) | 2004-12-15 |
PL356963A1 (en) | 2004-07-12 |
DK2100616T3 (en) | 2016-02-08 |
WO2001051082A1 (en) | 2001-07-19 |
EP1255563A1 (en) | 2002-11-13 |
EP1255563B2 (en) | 2016-03-02 |
CZ20022417A3 (cs) | 2003-03-12 |
US8470331B2 (en) | 2013-06-25 |
CZ304941B6 (cs) | 2015-02-04 |
JP4648603B2 (ja) | 2011-03-09 |
CA2397359A1 (en) | 2001-07-19 |
AR027924A1 (es) | 2003-04-16 |
CA2397359C (en) | 2012-06-05 |
EP1255563B1 (en) | 2009-07-22 |
EP2322212A1 (en) | 2011-05-18 |
AU2001228625A1 (en) | 2001-07-24 |
DE60139305D1 (de) | 2009-09-03 |
ES2561360T3 (es) | 2016-02-25 |
US20030165512A1 (en) | 2003-09-04 |
GB0000891D0 (en) | 2000-03-08 |
HU230545B1 (hu) | 2016-11-28 |
EP2100616A2 (en) | 2009-09-16 |
EP2100616A3 (en) | 2009-09-23 |
ES2328336T3 (es) | 2009-11-12 |
SK10412002A3 (sk) | 2003-05-02 |
SK288411B6 (sk) | 2016-10-03 |
HUP0203972A3 (en) | 2011-02-28 |
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