DE60139305D1 - Zusammensetzung aus antigen und glykolipid zur sublingualen verabreichung - Google Patents
Zusammensetzung aus antigen und glykolipid zur sublingualen verabreichungInfo
- Publication number
- DE60139305D1 DE60139305D1 DE60139305T DE60139305T DE60139305D1 DE 60139305 D1 DE60139305 D1 DE 60139305D1 DE 60139305 T DE60139305 T DE 60139305T DE 60139305 T DE60139305 T DE 60139305T DE 60139305 D1 DE60139305 D1 DE 60139305D1
- Authority
- DE
- Germany
- Prior art keywords
- glycolipide
- antigen
- sub
- composition
- lingual administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0000891.2A GB0000891D0 (en) | 2000-01-14 | 2000-01-14 | Formulation |
PCT/GB2001/000142 WO2001051082A1 (en) | 2000-01-14 | 2001-01-15 | Composition of antigen and glycolipid adjuvant sublingual administration |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60139305D1 true DE60139305D1 (de) | 2009-09-03 |
Family
ID=9883730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60139305T Expired - Lifetime DE60139305D1 (de) | 2000-01-14 | 2001-01-15 | Zusammensetzung aus antigen und glykolipid zur sublingualen verabreichung |
Country Status (15)
Country | Link |
---|---|
US (1) | US8470331B2 (de) |
EP (3) | EP2322212A1 (de) |
JP (1) | JP4648603B2 (de) |
AR (1) | AR027924A1 (de) |
AU (1) | AU2001228625A1 (de) |
CA (1) | CA2397359C (de) |
CZ (1) | CZ304941B6 (de) |
DE (1) | DE60139305D1 (de) |
DK (1) | DK2100616T3 (de) |
ES (2) | ES2328336T5 (de) |
GB (2) | GB0000891D0 (de) |
HU (1) | HU230545B1 (de) |
PL (1) | PL356963A1 (de) |
SK (1) | SK288411B6 (de) |
WO (1) | WO2001051082A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060025726A1 (en) * | 1996-06-04 | 2006-02-02 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with pharmacologically active layer |
US20060030826A1 (en) * | 1996-06-04 | 2006-02-09 | Vance Products Incorporated,d/b/a Cook Urological Incorporated | Implantable medical device with anti-neoplastic drug |
US20060052757A1 (en) * | 1996-06-04 | 2006-03-09 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with analgesic or anesthetic |
GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
MXPA05005528A (es) | 2002-11-26 | 2006-04-05 | Alk Abello As | Producto farmaceutico de alergeno. |
US8012505B2 (en) | 2003-02-28 | 2011-09-06 | Alk-Abello A/S | Dosage form having a saccharide matrix |
WO2005115449A1 (en) * | 2004-05-28 | 2005-12-08 | Alk-Abelló A/S | Method of treating allergy and infection by eliciting an iga antibody response |
ITMI20061117A1 (it) * | 2006-06-09 | 2007-12-10 | Michele Bonanomi | Una composizione farmaceutica per la somministrazione sublinguale di vaccini metodo per la sua preparazione e sui usi |
TR201807756T4 (tr) | 2006-09-26 | 2018-06-21 | Infectious Disease Res Inst | Sentetik adjuvan içeren aşı bileşimi. |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
US9545455B2 (en) * | 2009-04-29 | 2017-01-17 | Pravin K. Muniyappa | Device and method for the diagnosis of gastrointestinal allergy |
EP2437753B1 (de) | 2009-06-05 | 2016-08-31 | Infectious Disease Research Institute | Synthetische glucopyranosyl-lipid-adjuvanzien und impfstoffzusammensetzungen die diese enthalten |
GB201009273D0 (en) * | 2010-06-03 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel vaccine |
AU2012243039B2 (en) | 2011-04-08 | 2017-07-13 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
JP5650780B2 (ja) | 2012-04-04 | 2015-01-07 | 日東電工株式会社 | ワクチン組成物 |
RS57420B1 (sr) | 2012-05-16 | 2018-09-28 | Immune Design Corp | Vakcine za hsv-2 |
CA2909221A1 (en) | 2013-04-18 | 2014-10-23 | Immune Design Corp. | Gla monotherapy for use in cancer treatment |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
US11246924B2 (en) | 2016-04-01 | 2022-02-15 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
JP2023518924A (ja) * | 2020-03-24 | 2023-05-09 | チョル アン,ビョン | 幼い哺乳動物の粘膜関連伝染性疾病を予防または治療するための血清組成物の製造方法、前記方法によって製造された血清組成物及びその用途 |
KR102151962B1 (ko) | 2020-03-24 | 2020-09-04 | 안병철 | 어린 포유동물의 전염성 질병을 예방 또는 치료하기 위한 혈청 조성물의 제조방법, 상기 방법에 의해 제조된 혈청 조성물 및 이의 용도 |
Family Cites Families (53)
Publication number | Priority date | Publication date | Assignee | Title |
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GB1128637A (en) | 1966-09-13 | 1968-09-25 | Beecham Group Ltd | Influenza vaccine |
US3541201A (en) | 1968-12-18 | 1970-11-17 | Ethan Alan Brown | Novel sodium chloride encapsulated injectionable substances |
GB1377074A (en) * | 1971-07-13 | 1974-12-11 | Beecham Group Ltd | Process for preparing injectable compositions |
GB1492973A (en) | 1974-02-16 | 1977-11-23 | Beecham Group Ltd | Process for preparing injectable compositions |
US4070455A (en) * | 1974-02-16 | 1978-01-24 | Beecham Group Limited | Process for preparing injectable desensitizing compositions and products thereof in microparticle form |
EP0182442B2 (de) | 1978-12-22 | 1996-04-03 | Biogen, Inc. | Rekombinante DNS-Moleküle und Verfahren zur Herstellung derselben |
US4258029A (en) * | 1979-04-23 | 1981-03-24 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
US4987237A (en) * | 1983-08-26 | 1991-01-22 | Ribi Immunochem Research, Inc. | Derivatives of monophosphoryl lipid A |
DE3521994A1 (de) * | 1985-06-20 | 1987-01-02 | Bayer Ag | N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
US5244663A (en) * | 1987-01-28 | 1993-09-14 | Medibrevex | Therapeutic method against allergy |
US4975420A (en) * | 1987-09-30 | 1990-12-04 | University Of Saskatchewan | Agents and procedures for provoking an immune response to GnRH and immuno sterilizing mammals |
FR2621916B1 (fr) * | 1987-10-19 | 1990-03-09 | Bioeurope | Derives de la l-tyrosine solubles dans l'eau et procede pour leur preparation |
US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
GB9106048D0 (en) | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccines |
CA2131442A1 (en) * | 1992-03-03 | 1993-09-04 | Seishi Tsuchiya | Oral vaccine |
ES2143716T3 (es) * | 1992-06-25 | 2000-05-16 | Smithkline Beecham Biolog | Composicion de vacuna que contiene adyuvantes. |
BR9405996A (pt) * | 1993-03-11 | 1995-12-19 | Secretech Inc | Mucoadesivos poliméricos na distribuição de imunógenos em superfícies mucosais |
SG48309A1 (en) * | 1993-03-23 | 1998-04-17 | Smithkline Beecham Biolog | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid a |
ATE196737T1 (de) * | 1993-05-25 | 2000-10-15 | American Cyanamid Co | Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus |
JPH09502604A (ja) | 1993-08-27 | 1997-03-18 | エンテリック リサーチ ラボラトリーズ インコーポレイテッド | Campylobacterjejuni抗原、並びにそれらの製造及び利用 |
GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
US5514665A (en) | 1993-12-30 | 1996-05-07 | University Of British Columbia | Method of preventing or reducing the risk of infection by bacterial pathogens utilizing simple and conjugated dextrans |
US5997873A (en) * | 1994-01-13 | 1999-12-07 | Mount Sinai School Of Medicine Of The City University Of New York | Method of preparation of heat shock protein 70-peptide complexes |
US5646115A (en) * | 1994-10-07 | 1997-07-08 | Heska Corporation | Ectoparasite saliva proteins and apparatus to collect such proteins |
WO1996025664A1 (en) | 1995-02-17 | 1996-08-22 | Immunotherapy, Inc. | Immunotherapy screening, prognosis, and treatment methods and compositions |
KR100201352B1 (ko) * | 1995-03-16 | 1999-06-15 | 성재갑 | 단일주사 백신 제형 |
GB9508785D0 (en) | 1995-04-29 | 1995-06-21 | Smithkline Beecham Plc | Novel compositions |
US5762943A (en) * | 1996-05-14 | 1998-06-09 | Ribi Immunochem Research, Inc. | Methods of treating type I hypersensitivity using monophosphoryl lipid A |
US5973128A (en) * | 1996-11-22 | 1999-10-26 | The Hospital For Sick Children Research And Development Lp | Glycolipid mimics and methods of use thereof |
JP2001519781A (ja) | 1997-03-10 | 2001-10-23 | バイエル・コーポレーシヨン | ワクチンとしてのウシの呼吸器および腸コロナウイルス |
TR199902437T2 (xx) * | 1997-04-01 | 2000-01-21 | Corixa Corporation | Monofosforil lipid A'ya ait sulu im�nolojik adjuvant terkipleri. |
US6491919B2 (en) * | 1997-04-01 | 2002-12-10 | Corixa Corporation | Aqueous immunologic adjuvant compostions of monophosphoryl lipid A |
GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
AU7983198A (en) * | 1997-06-23 | 1999-01-04 | Ludwig Institute For Cancer Research | Improved methods for inducing an immune response |
GB9717953D0 (en) | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
GB9720585D0 (en) | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
EP1029053A1 (de) * | 1997-11-10 | 2000-08-23 | Statens Seruminstitut | Nukleinsäurefragmente und polypeptide von mycobacterium tuberculosis |
WO1999064074A1 (en) | 1998-06-11 | 1999-12-16 | The Trustees Of The University Of Pennsylvania | Methods and compositions for delivering proteins to macrophage cells and cells of macrophage derived lineage |
CA2330209A1 (en) | 1998-06-12 | 1999-12-23 | Smithkline Beecham Biologicals S.A. | Recombinant production of toxoplasma sag1 antigen |
CA2337823A1 (en) * | 1998-06-26 | 2000-01-06 | Bernard Meignier | Mucosal targeting immunisation |
GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
US6734172B2 (en) * | 1998-11-18 | 2004-05-11 | Pacific Northwest Research Institute | Surface receptor antigen vaccines |
EP1031347B1 (de) | 1999-01-27 | 2002-04-17 | Idea Ag | Transnasaler Transport bzw. Impfung mit hochadaptierbaren Trägern |
AU4673099A (en) * | 1999-02-26 | 2000-09-14 | Chiron Corporation | Use of bioadhesives and adjuvants for the mucosal delivery of antigens |
GB9909077D0 (en) * | 1999-04-20 | 1999-06-16 | Smithkline Beecham Biolog | Novel compositions |
TR200103046T2 (tr) * | 1999-04-23 | 2002-06-21 | Pharmexa A/S | IL5 aktivitesini düşürmek için yöntem. |
UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
WO2000076476A1 (en) | 1999-06-11 | 2000-12-21 | Endorex Corporation | Adjuvant-containing polymerized liposomes for oral, mucosal or intranasal vaccination |
GB9924529D0 (en) * | 1999-10-15 | 1999-12-15 | Smithkline Beecham Biolog | Novel compounds |
WO2001095914A1 (en) * | 2000-06-14 | 2001-12-20 | William Leslie Porter | Lipids for modulating immune response |
GB0020089D0 (en) | 2000-08-15 | 2000-10-04 | Smithkline Beecham Biolog | Vaccine Composition |
-
2000
- 2000-01-14 GB GBGB0000891.2A patent/GB0000891D0/en active Pending
-
2001
- 2001-01-12 AR ARP010100157A patent/AR027924A1/es unknown
- 2001-01-15 CA CA2397359A patent/CA2397359C/en not_active Expired - Lifetime
- 2001-01-15 DK DK09159908.4T patent/DK2100616T3/en active
- 2001-01-15 PL PL01356963A patent/PL356963A1/xx unknown
- 2001-01-15 WO PCT/GB2001/000142 patent/WO2001051082A1/en active Application Filing
- 2001-01-15 JP JP2001551505A patent/JP4648603B2/ja not_active Expired - Fee Related
- 2001-01-15 ES ES01942305.2T patent/ES2328336T5/es not_active Expired - Lifetime
- 2001-01-15 EP EP10011044A patent/EP2322212A1/de not_active Withdrawn
- 2001-01-15 ES ES09159908.4T patent/ES2561360T3/es not_active Expired - Lifetime
- 2001-01-15 GB GB0101035A patent/GB2360210B/en not_active Expired - Lifetime
- 2001-01-15 SK SK1041-2002A patent/SK288411B6/sk not_active IP Right Cessation
- 2001-01-15 HU HU0203972A patent/HU230545B1/hu unknown
- 2001-01-15 EP EP09159908.4A patent/EP2100616B1/de not_active Expired - Lifetime
- 2001-01-15 CZ CZ2002-2417A patent/CZ304941B6/cs not_active IP Right Cessation
- 2001-01-15 DE DE60139305T patent/DE60139305D1/de not_active Expired - Lifetime
- 2001-01-15 US US10/181,684 patent/US8470331B2/en not_active Expired - Lifetime
- 2001-01-15 AU AU2001228625A patent/AU2001228625A1/en not_active Abandoned
- 2001-01-15 EP EP01942305.2A patent/EP1255563B2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
GB2360210A (en) | 2001-09-19 |
ES2328336T5 (es) | 2016-06-21 |
US20030165512A1 (en) | 2003-09-04 |
AR027924A1 (es) | 2003-04-16 |
GB0101035D0 (en) | 2001-02-28 |
SK10412002A3 (sk) | 2003-05-02 |
HUP0203972A3 (en) | 2011-02-28 |
EP1255563A1 (de) | 2002-11-13 |
JP4648603B2 (ja) | 2011-03-09 |
EP2100616B1 (de) | 2015-11-25 |
CA2397359C (en) | 2012-06-05 |
CA2397359A1 (en) | 2001-07-19 |
CZ20022417A3 (cs) | 2003-03-12 |
ES2561360T3 (es) | 2016-02-25 |
GB0000891D0 (en) | 2000-03-08 |
DK2100616T3 (en) | 2016-02-08 |
EP1255563B2 (de) | 2016-03-02 |
EP2100616A3 (de) | 2009-09-23 |
SK288411B6 (sk) | 2016-10-03 |
EP2100616A2 (de) | 2009-09-16 |
JP2003519669A (ja) | 2003-06-24 |
EP1255563B1 (de) | 2009-07-22 |
CZ304941B6 (cs) | 2015-02-04 |
US8470331B2 (en) | 2013-06-25 |
HUP0203972A2 (hu) | 2003-03-28 |
EP2322212A1 (de) | 2011-05-18 |
HU230545B1 (hu) | 2016-11-28 |
GB2360210B (en) | 2004-12-15 |
PL356963A1 (en) | 2004-07-12 |
WO2001051082A1 (en) | 2001-07-19 |
ES2328336T3 (es) | 2009-11-12 |
AU2001228625A1 (en) | 2001-07-24 |
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