HUP0302556A2 - Biszfoszfonátok fájdalomcsillapítóként való alkalmazása - Google Patents
Biszfoszfonátok fájdalomcsillapítóként való alkalmazásaInfo
- Publication number
- HUP0302556A2 HUP0302556A2 HU0302556A HUP0302556A HUP0302556A2 HU P0302556 A2 HUP0302556 A2 HU P0302556A2 HU 0302556 A HU0302556 A HU 0302556A HU P0302556 A HUP0302556 A HU P0302556A HU P0302556 A2 HUP0302556 A2 HU P0302556A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- pain
- bisphosphonates
- bisphosphonate
- patient
- Prior art date
Links
- 229940122361 Bisphosphonate Drugs 0.000 title abstract 3
- 150000004663 bisphosphonates Chemical class 0.000 title abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 230000001009 osteoporotic effect Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 201000003068 rheumatic fever Diseases 0.000 abstract 1
- 230000005740 tumor formation Effects 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
- XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 abstract 1
- 229960004276 zoledronic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány tárgya eljárás fájdalom kezelésére ilyen kezelést igénylőbetegben, azzal jellemezve, hogy egy biszfoszfonátból hatékonymennyiséget adagolnak a betegnek, valamint a biszfoszfonát alkalmazásafájdalom, különösen emlősökben betegségekkel vagy patológiásállapotokkal összefüggő fájdalom kezelésére használható gyógyszerelőállítására, így például a zoledronsav és származékaifelhasználhatók a csontritkulás reumás izületi gyulladással,csontízületi gyulladással és tumor képződésével (pl. a tumornövekedésével, behatolásával vagy áttétekkel) együtt járó fájdalomkezelésére. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0029111.2A GB0029111D0 (en) | 2000-11-29 | 2000-11-29 | Organic compounds |
PCT/EP2001/013836 WO2002043738A2 (en) | 2000-11-29 | 2001-11-27 | Use of bisphosphonates for pain treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0302556A2 true HUP0302556A2 (hu) | 2003-11-28 |
HUP0302556A3 HUP0302556A3 (en) | 2005-02-28 |
Family
ID=9904112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0302556A HUP0302556A3 (en) | 2000-11-29 | 2001-11-27 | Use of bisphosphonates for pain treatment |
Country Status (27)
Country | Link |
---|---|
US (2) | US20040063670A1 (hu) |
EP (1) | EP1339411B1 (hu) |
JP (1) | JP2004514696A (hu) |
KR (2) | KR20080043409A (hu) |
CN (1) | CN1535152A (hu) |
AT (1) | ATE366112T1 (hu) |
AU (2) | AU2002217061B2 (hu) |
BR (1) | BR0115696A (hu) |
CA (1) | CA2427161C (hu) |
CY (1) | CY1106851T1 (hu) |
CZ (1) | CZ301701B6 (hu) |
DE (1) | DE60129242T2 (hu) |
DK (1) | DK1339411T3 (hu) |
ES (1) | ES2287191T3 (hu) |
GB (1) | GB0029111D0 (hu) |
HU (1) | HUP0302556A3 (hu) |
IL (2) | IL155363A0 (hu) |
MX (1) | MXPA03004815A (hu) |
NO (1) | NO20032405L (hu) |
NZ (1) | NZ525871A (hu) |
PL (1) | PL204001B1 (hu) |
PT (1) | PT1339411E (hu) |
RU (1) | RU2325913C2 (hu) |
SK (1) | SK287501B6 (hu) |
TW (1) | TWI275393B (hu) |
WO (1) | WO2002043738A2 (hu) |
ZA (1) | ZA200303247B (hu) |
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US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
US7425549B2 (en) | 2001-02-06 | 2008-09-16 | The Royal Alexandra Hospital For Children | Drug for the treatment of osteonecrosis and for the management of patients at risk of developing osteonecrosis |
US7875597B2 (en) * | 2002-07-24 | 2011-01-25 | New York University | Treatment of spinal mechanical pain |
CA2554749A1 (en) * | 2004-01-30 | 2005-08-11 | Astellas Pharma Inc. | P2x receptor inhibitor |
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US7473684B2 (en) * | 2005-09-16 | 2009-01-06 | Selamine Limited | Bisphosphonate formulation |
JP2009508834A (ja) * | 2005-09-16 | 2009-03-05 | セラマイン リミテッド | ビスホスホネート製剤 |
EP2007397B1 (en) | 2006-04-07 | 2013-07-24 | Merrion Research III Limited | Solid oral dosage form containing an enhancer |
GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
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GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
US8974801B2 (en) | 2006-12-21 | 2015-03-10 | Amphastar Pharmaceuticals Inc. | Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate |
ITPA20070034A1 (it) * | 2007-10-30 | 2009-04-30 | Tetrapharm S R L | Bifosfonati geminali, loro preparazione e loro impiego in campo oncologico. |
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US20110034418A1 (en) * | 2008-04-04 | 2011-02-10 | Karen Beltz | Pharmaceutical composition with bisphosphonate |
TW200950799A (en) | 2008-05-07 | 2009-12-16 | Merrion Res Iii Ltd | Compositions of GnRH related compounds and processes of preparation |
EP2382223A1 (en) * | 2008-12-23 | 2011-11-02 | Novartis AG | Phenylalkyl-imidazole-bisphosphonate compounds |
WO2011120033A1 (en) | 2010-03-26 | 2011-09-29 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor xa inhibitors for oral administration |
GB201011552D0 (en) * | 2010-07-09 | 2010-08-25 | Smith & Nephew | Adhesive and a method of delivery |
WO2012028891A1 (en) | 2010-09-02 | 2012-03-08 | Debreceni Egyetem | Perorally applicable preparation containing histaminase of vegetable origin, resistant to pepsin and trypsin and a process for producing it |
ITNA20100046A1 (it) * | 2010-09-28 | 2012-03-29 | Abbruzzese Saccardi Alberto | Uso di bisfosfonati per la preparazione di formulazioni farmaceutiche per il trattamento dei sintomi associati a dolore neuropatico |
CA2819234A1 (en) | 2011-01-07 | 2012-07-12 | Merrion Research Iii Limited | Pharmaceutical compositions of iron for oral administration |
AU2012352528B9 (en) * | 2011-12-11 | 2017-11-02 | Baudax Bio, Inc. | Intranasal dexmedetomidine compositions and methods of use thereof |
US9616078B2 (en) | 2012-05-14 | 2017-04-11 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
US10016445B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9669040B2 (en) * | 2012-05-14 | 2017-06-06 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
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US10413561B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
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DE19731205A1 (de) * | 1997-07-21 | 1999-01-28 | Siemens Ag | Verfahren und Funk-Kommunikationssystem zur Informationsübertragung mittels ATM-Zellen |
US6015801A (en) * | 1997-07-22 | 2000-01-18 | Merck & Co., Inc. | Method for inhibiting bone resorption |
PL347630A1 (en) * | 1998-11-12 | 2002-04-22 | Frank G Pilkiewicz | An inhalation system |
US6331533B1 (en) * | 1998-11-16 | 2001-12-18 | Merck & Co., Inc. | Method for inhibiting dental resorptive lesions |
DE10049404C2 (de) * | 2000-10-05 | 2003-01-30 | Fraunhofer Ges Forschung | Mit einem NIR-Marker versehener kunststoff-, glas-, textil- oder papierhaltiger Werkstoff und Verfahren zur Identifizierung dieses Werkstoffs |
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2000
- 2000-11-29 GB GBGB0029111.2A patent/GB0029111D0/en not_active Ceased
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2001
- 2001-11-27 AU AU2002217061A patent/AU2002217061B2/en not_active Ceased
- 2001-11-27 WO PCT/EP2001/013836 patent/WO2002043738A2/en active IP Right Grant
- 2001-11-27 IL IL15536301A patent/IL155363A0/xx active IP Right Grant
- 2001-11-27 PT PT01998352T patent/PT1339411E/pt unknown
- 2001-11-27 AU AU1706102A patent/AU1706102A/xx active Pending
- 2001-11-27 ES ES01998352T patent/ES2287191T3/es not_active Expired - Lifetime
- 2001-11-27 KR KR1020087010650A patent/KR20080043409A/ko not_active Application Discontinuation
- 2001-11-27 CA CA2427161A patent/CA2427161C/en not_active Expired - Fee Related
- 2001-11-27 MX MXPA03004815A patent/MXPA03004815A/es not_active Application Discontinuation
- 2001-11-27 KR KR1020037005600A patent/KR100866025B1/ko not_active IP Right Cessation
- 2001-11-27 DK DK01998352T patent/DK1339411T3/da active
- 2001-11-27 SK SK654-2003A patent/SK287501B6/sk not_active IP Right Cessation
- 2001-11-27 EP EP01998352A patent/EP1339411B1/en not_active Expired - Lifetime
- 2001-11-27 NZ NZ525871A patent/NZ525871A/en not_active IP Right Cessation
- 2001-11-27 BR BR0115696-9A patent/BR0115696A/pt not_active Application Discontinuation
- 2001-11-27 CN CNA018197841A patent/CN1535152A/zh active Pending
- 2001-11-27 US US10/432,847 patent/US20040063670A1/en not_active Abandoned
- 2001-11-27 RU RU2003117702/14A patent/RU2325913C2/ru not_active IP Right Cessation
- 2001-11-27 JP JP2002545708A patent/JP2004514696A/ja active Pending
- 2001-11-27 DE DE60129242T patent/DE60129242T2/de not_active Expired - Lifetime
- 2001-11-27 AT AT01998352T patent/ATE366112T1/de active
- 2001-11-27 CZ CZ20031467A patent/CZ301701B6/cs not_active IP Right Cessation
- 2001-11-27 PL PL361774A patent/PL204001B1/pl unknown
- 2001-11-27 HU HU0302556A patent/HUP0302556A3/hu unknown
- 2001-11-28 TW TW090129419A patent/TWI275393B/zh not_active IP Right Cessation
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2003
- 2003-04-10 IL IL155363A patent/IL155363A/en not_active IP Right Cessation
- 2003-04-25 ZA ZA200303247A patent/ZA200303247B/en unknown
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2007
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2008
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