BR0115696A - Uso de bisfosfonatos para tratamento de dor - Google Patents
Uso de bisfosfonatos para tratamento de dorInfo
- Publication number
- BR0115696A BR0115696A BR0115696-9A BR0115696A BR0115696A BR 0115696 A BR0115696 A BR 0115696A BR 0115696 A BR0115696 A BR 0115696A BR 0115696 A BR0115696 A BR 0115696A
- Authority
- BR
- Brazil
- Prior art keywords
- patient
- bisphosphonates
- pain
- treatment
- pain management
- Prior art date
Links
- 229940122361 Bisphosphonate Drugs 0.000 title abstract 3
- 150000004663 bisphosphonates Chemical class 0.000 title abstract 3
- 208000029725 Metabolic bone disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010049088 Osteopenia Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 230000003502 anti-nociceptive effect Effects 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 abstract 1
- 229960004276 zoledronic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
"USO DE BISFOSFONATOS PARA TRATAMENTO DE DOR". A invenção refere-se a um método para o tratamento de dor, em particular, tratamento antinociceptivo ou antialodínico de dor, em um paciente que necessite de semelhante tratamento, por exemplo, um paciente com osteoporose ou osteopenia, um paciente com tumor ou um paciente sofrendo de uma doença inflamatória, o qual compreende administrar uma quantidade eficaz de um bisfosfonato, por exemplo, ácido zoledrónico ou sais ou hidratos dos mesmos, para o paciente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0029111.2A GB0029111D0 (en) | 2000-11-29 | 2000-11-29 | Organic compounds |
PCT/EP2001/013836 WO2002043738A2 (en) | 2000-11-29 | 2001-11-27 | Use of bisphosphonates for pain treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0115696A true BR0115696A (pt) | 2004-02-10 |
Family
ID=9904112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0115696-9A BR0115696A (pt) | 2000-11-29 | 2001-11-27 | Uso de bisfosfonatos para tratamento de dor |
Country Status (27)
Country | Link |
---|---|
US (2) | US20040063670A1 (pt) |
EP (1) | EP1339411B1 (pt) |
JP (1) | JP2004514696A (pt) |
KR (2) | KR100866025B1 (pt) |
CN (1) | CN1535152A (pt) |
AT (1) | ATE366112T1 (pt) |
AU (2) | AU2002217061B2 (pt) |
BR (1) | BR0115696A (pt) |
CA (1) | CA2427161C (pt) |
CY (1) | CY1106851T1 (pt) |
CZ (1) | CZ301701B6 (pt) |
DE (1) | DE60129242T2 (pt) |
DK (1) | DK1339411T3 (pt) |
ES (1) | ES2287191T3 (pt) |
GB (1) | GB0029111D0 (pt) |
HU (1) | HUP0302556A3 (pt) |
IL (2) | IL155363A0 (pt) |
MX (1) | MXPA03004815A (pt) |
NO (1) | NO20032405D0 (pt) |
NZ (1) | NZ525871A (pt) |
PL (1) | PL204001B1 (pt) |
PT (1) | PT1339411E (pt) |
RU (1) | RU2325913C2 (pt) |
SK (1) | SK287501B6 (pt) |
TW (1) | TWI275393B (pt) |
WO (1) | WO2002043738A2 (pt) |
ZA (1) | ZA200303247B (pt) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8119159B2 (en) | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
PL361909A1 (en) | 2001-02-06 | 2004-10-04 | The Royal Alexandra Hospital For Children | A drug for the treatment of osteonecrosis and for the management of patients at risk of developing osteonecrosis |
US7875597B2 (en) * | 2002-07-24 | 2011-01-25 | New York University | Treatment of spinal mechanical pain |
JPWO2005072746A1 (ja) * | 2004-01-30 | 2007-10-11 | アステラス製薬株式会社 | P2x受容体阻害剤 |
WO2005107751A1 (en) | 2004-05-06 | 2005-11-17 | Merck & Co., Inc. | Methods for treating arthritic conditions in dogs |
KR20070043043A (ko) * | 2004-08-23 | 2007-04-24 | 테바 파마슈티컬 인더스트리즈 리미티드 | 고체 및 결정 이반드로네이트 나트륨 및 이들의 제조 방법 |
JP2009508834A (ja) * | 2005-09-16 | 2009-03-05 | セラマイン リミテッド | ビスホスホネート製剤 |
US7473684B2 (en) * | 2005-09-16 | 2009-01-06 | Selamine Limited | Bisphosphonate formulation |
AU2007235251B2 (en) | 2006-04-07 | 2013-02-07 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
GB0624090D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amine salts |
GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
US8974801B2 (en) | 2006-12-21 | 2015-03-10 | Amphastar Pharmaceuticals Inc. | Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate |
ITPA20070034A1 (it) * | 2007-10-30 | 2009-04-30 | Tetrapharm S R L | Bifosfonati geminali, loro preparazione e loro impiego in campo oncologico. |
US7977323B2 (en) | 2007-11-30 | 2011-07-12 | Novartis Ag | C2-C5-alkyl-imidazole-bisphosphonates |
CN102046152A (zh) * | 2008-04-04 | 2011-05-04 | 诺瓦提斯公司 | 含有双膦酸盐的药物组合物 |
WO2009137078A1 (en) | 2008-05-07 | 2009-11-12 | Merrion Research Iii Limited | Compositions of peptides and processes of preparation thereof |
CA2746612A1 (en) * | 2008-12-23 | 2010-07-08 | Novartis Ag | Phenylalkyl-imidazole-bisphosphonate compounds |
US9089484B2 (en) | 2010-03-26 | 2015-07-28 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor Xa inhibitors for oral administration |
GB201011552D0 (en) * | 2010-07-09 | 2010-08-25 | Smith & Nephew | Adhesive and a method of delivery |
ES2540828T3 (es) | 2010-09-02 | 2015-07-13 | Naturland Magyarország Termelö És Kereskedelmi Kft. | Preparación aplicable por vía peroral que contiene histaminasa de origen vegetal, resistente a pepsina y tripsina y un procedimiento para producirla |
ITNA20100046A1 (it) * | 2010-09-28 | 2012-03-29 | Abbruzzese Saccardi Alberto | Uso di bisfosfonati per la preparazione di formulazioni farmaceutiche per il trattamento dei sintomi associati a dolore neuropatico |
US8802114B2 (en) | 2011-01-07 | 2014-08-12 | Merrion Research Iii Limited | Pharmaceutical compositions of iron for oral administration |
SG10201604653TA (en) * | 2011-12-11 | 2016-07-28 | Recro Pharma Inc | Intranasal dexmedetomidine compositions and methods of use thereof |
US10413561B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
US9789128B2 (en) | 2012-05-14 | 2017-10-17 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9662343B2 (en) | 2012-05-14 | 2017-05-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US20150051175A1 (en) * | 2012-05-14 | 2015-02-19 | Antecip Bioventures Ii Llc | Co-Administration of Steroids and Zoledronic Acid to Prevent and Treat Pain |
US9700570B2 (en) | 2014-05-27 | 2017-07-11 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
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US9877977B2 (en) | 2012-05-14 | 2018-01-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9949993B2 (en) | 2012-05-14 | 2018-04-24 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US8865757B1 (en) | 2014-05-28 | 2014-10-21 | Antecip Bioventures Ii Llp | Therapeutic compositions comprising imidazole and imidazolium compounds |
PT2849758T (pt) * | 2012-05-14 | 2018-05-09 | Antecip Bioventures Ii Llc | Composições que compreendem o ácido zoledrónico ou compostos relacionados para o alívio da dor inflamatória e estados relacionados |
US10080765B2 (en) | 2012-05-14 | 2018-09-25 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US10092581B2 (en) | 2014-05-15 | 2018-10-09 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
US10493085B2 (en) | 2012-05-14 | 2019-12-03 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
US9782421B1 (en) | 2012-05-14 | 2017-10-10 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
US9694023B2 (en) | 2012-05-14 | 2017-07-04 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
US9717747B2 (en) | 2012-05-14 | 2017-08-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
US9427403B2 (en) | 2012-05-14 | 2016-08-30 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
US9901589B2 (en) * | 2012-05-14 | 2018-02-27 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US8802658B2 (en) * | 2012-05-14 | 2014-08-12 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
US9795622B2 (en) | 2012-05-14 | 2017-10-24 | Antecip Bioventures Ii Llc | Neridronic acid for treating pain associated with a joint |
US9675626B2 (en) | 2012-05-14 | 2017-06-13 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9956234B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
US9999628B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US10028969B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9867839B2 (en) | 2012-05-14 | 2018-01-16 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
US9827192B2 (en) | 2012-05-14 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9925203B2 (en) | 2012-05-14 | 2018-03-27 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US9669040B2 (en) | 2012-05-14 | 2017-06-06 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9867840B2 (en) | 2014-05-27 | 2018-01-16 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US20170095488A1 (en) * | 2012-05-14 | 2017-04-06 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9820999B2 (en) | 2012-05-14 | 2017-11-21 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US10016446B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone |
US9655908B2 (en) | 2012-05-14 | 2017-05-23 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
US9943531B2 (en) | 2014-08-08 | 2018-04-17 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
US20170056427A1 (en) * | 2012-05-14 | 2017-03-02 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
US10039773B2 (en) | 2012-05-14 | 2018-08-07 | Antecip Bioventures Ii Llc | Neridronic acid for treating arthritis |
US10004756B2 (en) | 2014-05-15 | 2018-06-26 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10111837B2 (en) | 2012-05-14 | 2018-10-30 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds |
US9956238B2 (en) | 2014-05-15 | 2018-05-01 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US10173986B2 (en) | 2012-05-14 | 2019-01-08 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
US9861648B2 (en) | 2012-05-14 | 2018-01-09 | Antecip Boiventures Ii Llc | Osteoclast inhibitors for knee conditions |
US9827256B2 (en) | 2014-05-27 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating lower back pain |
US10028908B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
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US10350227B2 (en) | 2012-05-14 | 2019-07-16 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US9616078B2 (en) | 2012-05-14 | 2017-04-11 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
US10016445B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US20170128472A1 (en) * | 2012-05-14 | 2017-05-11 | Antecip Bioventures Ii Llc | Administration of Zoledronic Acid to Treat Pain Associated with Ankylosing Spondylitis |
US20170071960A1 (en) * | 2012-05-14 | 2017-03-16 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
US9707247B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US9707245B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US11654152B2 (en) | 2012-05-14 | 2023-05-23 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
US9999629B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9895383B2 (en) | 2012-05-14 | 2018-02-20 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10034890B2 (en) | 2012-05-14 | 2018-07-31 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US20170065625A1 (en) * | 2012-05-14 | 2017-03-09 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
US10463682B2 (en) | 2012-05-14 | 2019-11-05 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating low back pain |
US9211257B2 (en) | 2012-05-14 | 2015-12-15 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
US9289441B2 (en) * | 2014-08-08 | 2016-03-22 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
US9844559B2 (en) | 2012-05-14 | 2017-12-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesions |
CN102961785A (zh) * | 2012-11-09 | 2013-03-13 | 于秀淳 | 一种用于治疗骨巨细胞瘤的瘤腔填充物及其制备方法 |
US8859530B2 (en) | 2013-03-08 | 2014-10-14 | Voltarra Pharmaceuticals, Inc. | Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis |
US9012432B2 (en) * | 2013-03-08 | 2015-04-21 | Levolta Pharmaceuticals, Inc. | Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis |
KR20190009428A (ko) * | 2013-10-25 | 2019-01-28 | 안테씨프 바이오벤쳐스 투 엘엘씨 | 질병의 치료를 위한, 졸레드론산 또는 관련 화합물의 경구 투여용 조성물 |
US9079927B1 (en) | 2014-05-27 | 2015-07-14 | Antecip Bioventures Ii Llc | Substituted imidazolium compounds for treating disease |
US9127069B1 (en) | 2014-06-11 | 2015-09-08 | Antecip Bioventures LLC | Compositions comprising rank/rankl antagonists and related compounds for treating pain |
US9688765B2 (en) | 2014-06-11 | 2017-06-27 | Antecip Bioventures Ii Llc | Methods using RANK/RANKL antagonist antibodies for treating pain |
US10265384B2 (en) | 2015-01-29 | 2019-04-23 | Novo Nordisk A/S | Tablets comprising GLP-1 agonist and enteric coating |
CN107011380A (zh) * | 2016-01-28 | 2017-08-04 | 臧伟 | 一种二膦酸衍生物及含二膦酸衍生物的组合物治疗骨折的应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5270365A (en) * | 1991-12-17 | 1993-12-14 | Merck & Co., Inc. | Prevention and treatment of periodontal disease with alendronate |
US5358941A (en) * | 1992-12-02 | 1994-10-25 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids with lactose |
FI92465C (fi) * | 1993-04-14 | 1994-11-25 | Risto Tapani Lehtinen | Menetelmä endo-osteaalisten materiaalien käsittelemiseksi |
US5646134A (en) * | 1994-04-21 | 1997-07-08 | Merck & Co., Inc. | Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices |
TW390813B (en) * | 1994-04-29 | 2000-05-21 | Merck & Co Inc | Wet granulation formulation for bisphosphonic acids |
GB9408775D0 (en) * | 1994-05-04 | 1994-06-22 | Ciba Geigy Ag | Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration |
US6008206A (en) * | 1994-09-21 | 1999-12-28 | Merck & Co., Inc. | Sodium alendronate preparation for local administration |
JP3411690B2 (ja) * | 1994-09-21 | 2003-06-03 | 帝人株式会社 | 局所投与用アレンドロン酸ナトリウム製剤 |
US5652227A (en) * | 1995-01-30 | 1997-07-29 | Teronen; Olli Pekka | Inhibition of the degradation of connective tissue matrix protein components in mammals |
AU713824B2 (en) * | 1995-05-12 | 1999-12-09 | Merck Sharp & Dohme Corp. | Prevention of tooth loss by the administration of alendronate or its salts |
CA2241473A1 (en) * | 1997-06-26 | 1998-12-26 | Reese Products, Inc. | Trailer shipping container |
DE19731205A1 (de) * | 1997-07-21 | 1999-01-28 | Siemens Ag | Verfahren und Funk-Kommunikationssystem zur Informationsübertragung mittels ATM-Zellen |
US6015801A (en) * | 1997-07-22 | 2000-01-18 | Merck & Co., Inc. | Method for inhibiting bone resorption |
ATE353630T1 (de) * | 1998-11-12 | 2007-03-15 | Transave Inc | Inhalationssystem |
US6331533B1 (en) * | 1998-11-16 | 2001-12-18 | Merck & Co., Inc. | Method for inhibiting dental resorptive lesions |
DE10049404C2 (de) * | 2000-10-05 | 2003-01-30 | Fraunhofer Ges Forschung | Mit einem NIR-Marker versehener kunststoff-, glas-, textil- oder papierhaltiger Werkstoff und Verfahren zur Identifizierung dieses Werkstoffs |
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2000
- 2000-11-29 GB GBGB0029111.2A patent/GB0029111D0/en not_active Ceased
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2001
- 2001-11-27 NZ NZ525871A patent/NZ525871A/en not_active IP Right Cessation
- 2001-11-27 SK SK654-2003A patent/SK287501B6/sk not_active IP Right Cessation
- 2001-11-27 CA CA2427161A patent/CA2427161C/en not_active Expired - Fee Related
- 2001-11-27 US US10/432,847 patent/US20040063670A1/en not_active Abandoned
- 2001-11-27 DK DK01998352T patent/DK1339411T3/da active
- 2001-11-27 AT AT01998352T patent/ATE366112T1/de active
- 2001-11-27 JP JP2002545708A patent/JP2004514696A/ja active Pending
- 2001-11-27 WO PCT/EP2001/013836 patent/WO2002043738A2/en active IP Right Grant
- 2001-11-27 AU AU2002217061A patent/AU2002217061B2/en not_active Ceased
- 2001-11-27 CN CNA018197841A patent/CN1535152A/zh active Pending
- 2001-11-27 EP EP01998352A patent/EP1339411B1/en not_active Expired - Lifetime
- 2001-11-27 KR KR1020037005600A patent/KR100866025B1/ko not_active IP Right Cessation
- 2001-11-27 BR BR0115696-9A patent/BR0115696A/pt not_active Application Discontinuation
- 2001-11-27 CZ CZ20031467A patent/CZ301701B6/cs not_active IP Right Cessation
- 2001-11-27 PT PT01998352T patent/PT1339411E/pt unknown
- 2001-11-27 HU HU0302556A patent/HUP0302556A3/hu unknown
- 2001-11-27 KR KR1020087010650A patent/KR20080043409A/ko not_active Application Discontinuation
- 2001-11-27 IL IL15536301A patent/IL155363A0/xx active IP Right Grant
- 2001-11-27 ES ES01998352T patent/ES2287191T3/es not_active Expired - Lifetime
- 2001-11-27 RU RU2003117702/14A patent/RU2325913C2/ru not_active IP Right Cessation
- 2001-11-27 PL PL361774A patent/PL204001B1/pl unknown
- 2001-11-27 MX MXPA03004815A patent/MXPA03004815A/es not_active Application Discontinuation
- 2001-11-27 DE DE60129242T patent/DE60129242T2/de not_active Expired - Lifetime
- 2001-11-27 AU AU1706102A patent/AU1706102A/xx active Pending
- 2001-11-28 TW TW090129419A patent/TWI275393B/zh not_active IP Right Cessation
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2003
- 2003-04-10 IL IL155363A patent/IL155363A/en not_active IP Right Cessation
- 2003-04-25 ZA ZA200303247A patent/ZA200303247B/en unknown
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2007
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2008
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