HUP0004653A2 - Biszfoszfonátok alkalmazása csontreszorpció gátlására szolgáló gyógyszerkészítmények előállítására - Google Patents
Biszfoszfonátok alkalmazása csontreszorpció gátlására szolgáló gyógyszerkészítmények előállításáraInfo
- Publication number
- HUP0004653A2 HUP0004653A2 HU0004653A HUP0004653A HUP0004653A2 HU P0004653 A2 HUP0004653 A2 HU P0004653A2 HU 0004653 A HU0004653 A HU 0004653A HU P0004653 A HUP0004653 A HU P0004653A HU P0004653 A2 HUP0004653 A2 HU P0004653A2
- Authority
- HU
- Hungary
- Prior art keywords
- unit dosage
- bone resorption
- mammal
- orally administering
- inhibiting bone
- Prior art date
Links
- 208000006386 Bone Resorption Diseases 0.000 title abstract 7
- 230000024279 bone resorption Effects 0.000 title abstract 7
- 230000002401 inhibitory effect Effects 0.000 title abstract 5
- 229940122361 Bisphosphonate Drugs 0.000 title abstract 2
- 150000004663 bisphosphonates Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 7
- OGSPWJRAVKPPFI-UHFFFAOYSA-N Alendronic Acid Chemical compound NCCCC(O)(P(O)(O)=O)P(O)(O)=O OGSPWJRAVKPPFI-UHFFFAOYSA-N 0.000 abstract 5
- 229960004343 alendronic acid Drugs 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 2
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 229940062527 alendronate Drugs 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940126409 proton pump inhibitor Drugs 0.000 abstract 1
- 239000000612 proton pump inhibitor Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány biszfoszfonátok alkalmazására vonatkozik csontreszorpciógátlására szolgáló gyógyszerkészítmények előállítására, amely lehetővéteszi a gyomor-bél rendszerbeli káros hatások potenciáliselőfordulásának minimalizálását. A találmány továbbá agyógyszerkészítményekre és -készletekre is vonatkozik. A találmányértelmében valamely biszfoszfonátot alkalmaznak, amely lehetalendronát, cimadronát, clodronát, tiludronát, etidronát, ibadronát,rizedronát, piridronát, pamidronát, zoledronát, adott esetbenhisztamin H2 blokkolószerrel kombinálva. Ó
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5335197P | 1997-07-22 | 1997-07-22 | |
US5353597P | 1997-07-23 | 1997-07-23 | |
GBGB9717590.5A GB9717590D0 (en) | 1997-08-20 | 1997-08-20 | Oral method for treating or preventing abnormal bone resorption |
GBGB9717850.3A GB9717850D0 (en) | 1997-08-22 | 1997-08-22 | Oral method for treating or preventing abnormal bone resorption |
US6041998A | 1998-04-15 | 1998-04-15 | |
PCT/US1998/014796 WO1999004773A2 (en) | 1997-07-22 | 1998-07-17 | Method for inhibiting bone resorption |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0004653A2 true HUP0004653A2 (hu) | 2001-04-28 |
HUP0004653A3 HUP0004653A3 (en) | 2002-12-28 |
Family
ID=27517421
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0004653A HUP0004653A3 (en) | 1997-07-22 | 1998-07-17 | The use of bisphosphonates for producing medicaments use ful for inhibiting bone resorption |
Country Status (2)
Country | Link |
---|---|
HU (1) | HUP0004653A3 (hu) |
TW (1) | TWI226833B (hu) |
-
1998
- 1998-07-17 HU HU0004653A patent/HUP0004653A3/hu unknown
- 1998-10-13 TW TW87116964A patent/TWI226833B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUP0004653A3 (en) | 2002-12-28 |
TWI226833B (en) | 2005-01-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB9A | Succession in title |
Owner name: MERCK SHARP & DOHME CORP., US Free format text: FORMER OWNER(S): MERCK & CO., INC., US |
|
GB9A | Succession in title |
Owner name: MERCK SHARP & DOHME CORP., US Free format text: FORMER OWNER(S): MERCK & CO., INC., US; MERCK SHARP & DOHME CORP., US; SCHERING CORPORATION, US |
|
HC9A | Change of name, address |
Owner name: MERCK SHARP & DOHME CORP., US Free format text: FORMER OWNER(S): MERCK & CO., INC., US; MERCK SHARP & DOHME CORP., US; SCHERING CORPORATION, US |
|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |