ATE372774T1 - Medikament zur verabreichung von amifostin und verwandten wirkstoffen - Google Patents
Medikament zur verabreichung von amifostin und verwandten wirkstoffenInfo
- Publication number
- ATE372774T1 ATE372774T1 AT02713473T AT02713473T ATE372774T1 AT E372774 T1 ATE372774 T1 AT E372774T1 AT 02713473 T AT02713473 T AT 02713473T AT 02713473 T AT02713473 T AT 02713473T AT E372774 T1 ATE372774 T1 AT E372774T1
- Authority
- AT
- Austria
- Prior art keywords
- administration
- amifostine
- medication
- related ingredients
- compounds
- Prior art date
Links
- JKOQGQFVAUAYPM-UHFFFAOYSA-N amifostine Chemical compound NCCCNCCSP(O)(O)=O JKOQGQFVAUAYPM-UHFFFAOYSA-N 0.000 title 1
- 229960001097 amifostine Drugs 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000004615 ingredient Substances 0.000 title 1
- -1 aminoalkyl phosphorothioate Chemical compound 0.000 abstract 2
- 230000002411 adverse Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000007423 decrease Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/775,540 US6573253B2 (en) | 1997-02-12 | 2001-02-05 | Methods for the administration of amifostine and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE372774T1 true ATE372774T1 (de) | 2007-09-15 |
Family
ID=25104730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02713473T ATE372774T1 (de) | 2001-02-05 | 2002-02-04 | Medikament zur verabreichung von amifostin und verwandten wirkstoffen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6573253B2 (de) |
| EP (1) | EP1368038B1 (de) |
| JP (1) | JP2005504720A (de) |
| AT (1) | ATE372774T1 (de) |
| AU (1) | AU2002245321B2 (de) |
| CA (1) | CA2437087A1 (de) |
| DE (1) | DE60222383T2 (de) |
| ES (1) | ES2289090T3 (de) |
| WO (1) | WO2002062350A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994409A (en) * | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
| AU2001253919B2 (en) * | 2000-04-26 | 2006-12-14 | Government Of The United States, D/B/A Department Of Veterans Affairs | Administration of a thiol-based chemoprotectant compound |
| US7053072B2 (en) * | 2001-05-11 | 2006-05-30 | Medimmune Oncology, Inc. | Methods for the administration of amifostine and related compounds |
| WO2004039336A2 (en) * | 2002-10-31 | 2004-05-13 | Oregon Health & Science University | Use of thiol-based compositions in treating chemotherapeutic agent-induced thrombocytopenia |
| WO2006044738A2 (en) * | 2004-10-18 | 2006-04-27 | Maroon Biotech Corporation | Methods and compositions for treatment of free radical injury |
| WO2008060989A2 (en) * | 2006-11-11 | 2008-05-22 | Uop Llc | Selective hydrogenation processes using functional surface catalyst composition |
| EP2141995B1 (de) | 2007-03-27 | 2014-11-05 | Perscitus Biosciences, LLC | Zusammensetzungen und ihre verwendungen zum schutz von zellen gegen toxische wirkungen |
| US20100049284A1 (en) * | 2008-05-15 | 2010-02-25 | The Catholic University Of America | Use of heat to treat biological systems exposed to damaging radiation |
| TWI432204B (zh) * | 2011-06-03 | 2014-04-01 | Taiwan Hopax Chems Mfg Co Ltd | 對抗自由基的醫藥組合物 |
| WO2013188016A2 (en) | 2012-05-04 | 2013-12-19 | Discovery Laboratories, Inc. | Surfactant therapy for exposure to ionizing radiation |
| EP3011339A4 (de) | 2013-06-18 | 2017-01-25 | Aminomedix Inc. | Zusammensetzungen und verfahren zur herstellung von nierenschutzmittel mit amifostin und aminosäuren |
| WO2019103983A1 (en) * | 2017-11-21 | 2019-05-31 | William Marsh Rice University | Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3892824A (en) | 1968-12-16 | 1975-07-01 | Southern Res Inst | S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates |
| AU629533B2 (en) | 1987-12-22 | 1992-10-08 | U.S. Bioscience, Inc. | Improving toxicity profiles in chemotherapy |
| AU636107B2 (en) | 1988-02-23 | 1993-04-22 | U.S. Bioscience, Inc. | Method for protection from chemotherapeutic side effects |
| US5869338A (en) | 1992-03-13 | 1999-02-09 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
| US5488042A (en) | 1992-03-13 | 1996-01-30 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
| US5567686A (en) | 1992-03-13 | 1996-10-22 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
| US5424471A (en) | 1992-07-31 | 1995-06-13 | U.S. Bioscience, Inc. | Crystalline amifostine compositions and methods of the preparation and use of same |
| SG47101A1 (en) | 1992-07-31 | 1998-03-20 | Us Bioscience | Crystalline amifostine compositions and methods for the preparation and use of same |
| CA2122342A1 (en) | 1992-09-04 | 1994-03-17 | Hironori Kawabata | Pharmaceutical composition |
| DE69526395D1 (de) | 1994-08-13 | 2002-05-23 | Roche Diagnostics Gmbh | Verwendung von Interferon-gamma zur Vermeidung der Proliferation und Differenzierung der primitiven Hämapoietischen Vorläuferzellen |
| US5846958A (en) | 1995-02-17 | 1998-12-08 | U.S. Bioscience, Inc. | Methods of using aminothiols to promote hematopoietic progenitor cell growth |
| US6051563A (en) | 1997-02-12 | 2000-04-18 | U.S. Bioscience, Inc. | Methods for the administration of amifostine and related compounds |
| US5994409A (en) | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
| US6984619B1 (en) | 1999-03-19 | 2006-01-10 | Arch Development Corporation | Method for protection against tumor metastasis formation |
-
2001
- 2001-02-05 US US09/775,540 patent/US6573253B2/en not_active Expired - Lifetime
-
2002
- 2002-02-04 DE DE60222383T patent/DE60222383T2/de not_active Expired - Lifetime
- 2002-02-04 JP JP2002562357A patent/JP2005504720A/ja active Pending
- 2002-02-04 ES ES02713473T patent/ES2289090T3/es not_active Expired - Lifetime
- 2002-02-04 EP EP02713473A patent/EP1368038B1/de not_active Expired - Lifetime
- 2002-02-04 AU AU2002245321A patent/AU2002245321B2/en not_active Expired
- 2002-02-04 AT AT02713473T patent/ATE372774T1/de not_active IP Right Cessation
- 2002-02-04 CA CA002437087A patent/CA2437087A1/en not_active Abandoned
- 2002-02-04 WO PCT/US2002/002256 patent/WO2002062350A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005504720A (ja) | 2005-02-17 |
| DE60222383D1 (de) | 2007-10-25 |
| AU2002245321B2 (en) | 2007-08-02 |
| WO2002062350A1 (en) | 2002-08-15 |
| US6573253B2 (en) | 2003-06-03 |
| CA2437087A1 (en) | 2002-08-15 |
| DE60222383T2 (de) | 2008-06-12 |
| EP1368038A1 (de) | 2003-12-10 |
| US20020035093A1 (en) | 2002-03-21 |
| EP1368038B1 (de) | 2007-09-12 |
| ES2289090T3 (es) | 2008-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |