HUP0202779A3 - Immunological process for detecting antibodies directed towards tissue transglutaminase (ttg), use of ttg for diagnostic purposes and therapy control, and oral pharmaceutical agent containing ttg - Google Patents

Immunological process for detecting antibodies directed towards tissue transglutaminase (ttg), use of ttg for diagnostic purposes and therapy control, and oral pharmaceutical agent containing ttg

Info

Publication number
HUP0202779A3
HUP0202779A3 HU0202779A HUP0202779A HUP0202779A3 HU P0202779 A3 HUP0202779 A3 HU P0202779A3 HU 0202779 A HU0202779 A HU 0202779A HU P0202779 A HUP0202779 A HU P0202779A HU P0202779 A3 HUP0202779 A3 HU P0202779A3
Authority
HU
Hungary
Prior art keywords
ttg
directed towards
agent containing
pharmaceutical agent
antibodies directed
Prior art date
Application number
HU0202779A
Other languages
English (en)
Original Assignee
Schuppan
Dieterich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7801172&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0202779(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schuppan, Dieterich filed Critical Schuppan
Publication of HUP0202779A2 publication Critical patent/HUP0202779A2/hu
Publication of HUP0202779A3 publication Critical patent/HUP0202779A3/hu
Publication of HU228479B1 publication Critical patent/HU228479B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Rehabilitation Therapy (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
HU0202779A 1996-07-18 1997-07-14 Immunological process for detecting antibodies directed towards tissue transglutaminase (ttg), use of ttg for diagnostic purposes and therapy control, and oral pharmaceutical agent containing ttg HU228479B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19630557A DE19630557C2 (de) 1996-07-18 1996-07-18 Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Gewebe-Transglutaminase (tTG) sowie die Verwendung von tTG in Diagnose und Therapie
PCT/EP1997/003740 WO1998003872A2 (de) 1996-07-18 1997-07-14 IMMUNOLOGISCHES NACHWEISVERFAHREN VON ANTIKÖRPERN, DIE GEGEN GEWEBE-TRANSGLUTAMINASE (tTG) GERICHTET SIND, VERWENDUNG VON tTG ZUR DIAGNOSE UND THERAPIEKONTROLLE SOWIE ORALES PHARMAZEUTISCHES MITTEL ENTHALTEND tTG

Publications (3)

Publication Number Publication Date
HUP0202779A2 HUP0202779A2 (hu) 2002-12-28
HUP0202779A3 true HUP0202779A3 (en) 2009-07-28
HU228479B1 HU228479B1 (en) 2013-03-28

Family

ID=7801172

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202779A HU228479B1 (en) 1996-07-18 1997-07-14 Immunological process for detecting antibodies directed towards tissue transglutaminase (ttg), use of ttg for diagnostic purposes and therapy control, and oral pharmaceutical agent containing ttg

Country Status (21)

Country Link
US (2) US6319726B1 (hu)
EP (1) EP0912898B1 (hu)
CN (1) CN1138146C (hu)
AT (1) ATE210296T1 (hu)
AU (1) AU718797B2 (hu)
BR (1) BR9710500B1 (hu)
CA (1) CA2260769C (hu)
CZ (1) CZ291662B6 (hu)
DE (2) DE19630557C2 (hu)
DK (1) DK0912898T3 (hu)
ES (1) ES2131038T3 (hu)
GR (1) GR990300020T1 (hu)
HU (1) HU228479B1 (hu)
IL (1) IL128042A (hu)
NO (1) NO321466B1 (hu)
NZ (1) NZ333744A (hu)
PL (1) PL189091B1 (hu)
PT (1) PT912898E (hu)
SI (1) SI9720044B (hu)
SK (1) SK284410B6 (hu)
WO (1) WO1998003872A2 (hu)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1075267A2 (en) * 1998-05-06 2001-02-14 Kobenhavns Universitet Treatment of celiac disease
WO2001001133A2 (en) * 1999-06-28 2001-01-04 Immundiagnostik Ag Diagnosis of gluten sensitive enteropathy and other autoimmunopathies
US6703208B1 (en) 1999-10-20 2004-03-09 Immco Diagnostics Immunological assay for detection of antibodies in celiac disease
EP1222210A4 (en) * 1999-10-20 2004-12-08 Immco Diagnostics IMMUNOASSAY METHOD FOR THE DETECTION OF ANTIBODIES OF A CELIAC DISEASE
CU22968A1 (es) * 2000-06-07 2004-07-14 Ct Ingenieria Genetica Biotech Procedimiento para la detección de anticuerpos anti transglutaminasa con utilidad en el diagnóstico de la enfermedad celíaca
GB0103024D0 (en) * 2001-02-07 2001-03-21 Rsr Ltd Assay for Autoantibodies to tissue transglutaminase
FI20010868A0 (fi) * 2001-04-25 2001-04-25 Markku Maeki Menetelmä ja välineet gluteenin indusoimien tautien havaitsemiseksi
KR100488131B1 (ko) * 2001-07-07 2005-05-06 (주)푸드바이오테크 알레르기 진단용 단백질 칩과 알레르기 유발원의 검출방법 및 알레르기 유발 항체의 검출 방법
GB0117870D0 (en) * 2001-07-21 2001-09-12 Univ Nottingham Trent Method of diagnosis and kit of parts therefor
US7320788B2 (en) * 2002-02-14 2008-01-22 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
DE60336754D1 (de) * 2002-02-14 2011-05-26 Univ R Enzymbehandlung von nahrungsmitteln für zöliakie-sprue
US8143210B2 (en) * 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
RU2234086C2 (ru) * 2002-05-08 2004-08-10 Нижегородский научно-исследовательский институт детской гастроэнтерологии Способ дифференциальной диагностики целиакии и хронического энтерита у детей с патологией тонкой кишки
US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7605150B2 (en) * 2002-05-14 2009-10-20 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
US7202216B2 (en) * 2002-05-14 2007-04-10 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
US7265093B2 (en) * 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
ES2383595T3 (es) * 2002-11-20 2012-06-22 The Board Of Trustees Of The Leland Stanford Junior University Procedimiento de diagnóstico de la celiaquía
US7579313B2 (en) * 2003-11-18 2009-08-25 The Board Of Trustees Of The Leland Stanford Junior University Transglutaminase inhibitors and methods of use thereof
US7563864B2 (en) * 2004-04-26 2009-07-21 Celiac Sprue Research Foundation Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
US7628985B2 (en) * 2004-04-26 2009-12-08 The Board Of Regents Of The Leland Stanford Junior University Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis
US7534426B2 (en) * 2004-04-26 2009-05-19 The Board Of Trustees Of The Leland Stanford Junior University Glutenase enzyme assays
US20080038760A1 (en) * 2004-06-08 2008-02-14 Method For Decting Anti-Transglutaminase Antibodies Method for Detecting Anti-Transglutaminase Antibodies
ES2558309T3 (es) 2006-07-25 2016-02-03 Augurix S.A. Dispositivo de inmunocromatografía para el diagnóstico de enfermedades en una muestra
JP5603083B2 (ja) * 2007-01-26 2014-10-08 ゲーアー ジェネリック アッセイズ ゲーエムベーハー 炎症性大腸炎及び慢性膵炎の診断のために、膵臓の酵素原顆粒由来の糖タンパク質２（ｇｐ２）との免疫反応を介して体液から抗体を検出する方法
WO2008115411A1 (en) * 2007-03-16 2008-09-25 The Board Of Trustees Of The Leland Stanford Junior University Combination enzyme therapy for digestion of dietary gluten
ATE511651T1 (de) 2007-04-06 2011-06-15 Zedira Gmbh Transglutaminase 6 als diagnostischer indikator für autoimmunerkrankungen
HU0900199D0 (en) * 2009-04-01 2009-06-29 Debreceni Egyetem Diagnosis of gluten-induced autoimmune diseases
FR2949782B1 (fr) * 2009-09-04 2015-10-16 Isp Investments Inc Peptide activateur de la transglutaminase et composition cosmetique ou pharmaceutique le contenant.
CA3191015A1 (en) 2012-02-07 2013-08-15 Vibrant Holdings, Llc Substrates, peptide arrays, and methods
TR201908080T4 (tr) 2012-04-17 2019-06-21 Aeneas Gmbh & Co Kg Gluten enteropati̇si̇ni̇n ve gluten hassasi̇yeti̇ni̇n presemptomati̇k tanisi i̇çi̇n yöntem
DE102012007510A1 (de) 2012-04-17 2013-10-17 Aesku.Diagnostics GmbH & Co. KG Verfahren zur Präsymptomatischen Diagnostik von Zöliakie und Glutensensitivität
US10006909B2 (en) 2012-09-28 2018-06-26 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
EP4030167B1 (en) 2013-02-15 2025-05-14 Vibrant Holdings, LLC Methods and compositions for amplified electrochemiluminescence detection
CN104090102B (zh) * 2014-06-13 2016-08-17 江南大学 冷冻鱼糜中微生物谷氨酰胺转胺酶elisa检测方法
EP3191629A4 (en) * 2014-09-10 2018-07-11 Vibrant Holdings, LLC Peptide microarrays and novel biomarkers for celiac disease
WO2018218250A2 (en) 2017-05-26 2018-11-29 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
EP3790985A4 (en) 2018-05-09 2022-02-16 Vibrant Holdings, LLC METHOD OF SYNTHESIS OF A POLYNUCLEOTIDARRAY USING PHOTOACTIVATED AGENTS
CN110055235A (zh) * 2019-05-14 2019-07-26 深圳市亚辉龙生物科技股份有限公司 用于转谷氨酰胺酶抗体检测的抗原及其制备方法、试剂盒及检测方法
WO2025233646A2 (en) 2024-05-09 2025-11-13 Debreceni Egyetem Detection of celiac disease-specific autoantibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL155894B1 (en) * 1987-12-23 1992-01-31 Przed Zagraniczne W Polsce Pla Test for assessing gluten-dependent enteropathies
DE3829524A1 (de) * 1988-08-31 1990-03-01 Behringwerke Ag Verwendung von transglutaminasen als immunsuppressiva
DE19520480C2 (de) 1995-06-03 1997-04-30 Univ Leipzig Immunochemisches Testmaterial und Enzymimmunoassay zur Diagnostik von Zöliakie und verwandten Eiweißintoleranzen
US5716794A (en) * 1996-03-29 1998-02-10 Xybernaut Corporation Celiac antigen

Also Published As

Publication number Publication date
PT912898E (pt) 2002-05-31
NZ333744A (en) 2000-03-27
NO990190L (no) 1999-03-15
CA2260769A1 (en) 1998-01-29
SK6799A3 (en) 2000-05-16
PL189091B1 (pl) 2005-06-30
SK284410B6 (sk) 2005-03-04
WO1998003872A2 (de) 1998-01-29
ES2131038T1 (es) 1999-07-16
AU4201197A (en) 1998-02-10
BR9710500B1 (pt) 2009-05-05
AU718797B2 (en) 2000-04-20
CN1138146C (zh) 2004-02-11
HUP0202779A2 (hu) 2002-12-28
HK1021025A1 (en) 2000-05-26
GR990300020T1 (en) 1999-06-30
DK0912898T3 (da) 2002-04-08
ES2131038T3 (es) 2002-09-01
WO1998003872A3 (de) 1998-03-12
NO321466B1 (no) 2006-05-15
ATE210296T1 (de) 2001-12-15
SI9720044B (sl) 2003-02-28
US20020076834A1 (en) 2002-06-20
HU228479B1 (en) 2013-03-28
PL331203A1 (en) 1999-07-05
EP0912898B1 (de) 2001-12-05
CZ291662B6 (cs) 2003-04-16
DE19630557C2 (de) 1998-07-02
BR9710500A (pt) 2000-01-18
IL128042A0 (en) 1999-11-30
DE19630557A1 (de) 1998-01-29
EP0912898A2 (de) 1999-05-06
CA2260769C (en) 2005-09-06
IL128042A (en) 2007-06-17
US6319726B1 (en) 2001-11-20
NO990190D0 (no) 1999-01-15
SI9720044A (sl) 1999-08-31
CZ11799A3 (cs) 1999-07-14
CN1225723A (zh) 1999-08-11
DE59705683D1 (de) 2002-01-17

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