HUP0102697A2 - Eljárás fehérjék előállítására transzformált élesztősejtekben - Google Patents

Eljárás fehérjék előállítására transzformált élesztősejtekben

Info

Publication number
HUP0102697A2
HUP0102697A2 HU0102697A HUP0102697A HUP0102697A2 HU P0102697 A2 HUP0102697 A2 HU P0102697A2 HU 0102697 A HU0102697 A HU 0102697A HU P0102697 A HUP0102697 A HU P0102697A HU P0102697 A2 HUP0102697 A2 HU P0102697A2
Authority
HU
Hungary
Prior art keywords
transformed yeast
yeast cells
yeast
making proteins
transformed
Prior art date
Application number
HU0102697A
Other languages
English (en)
Inventor
Thomas Kjeldsen
Knud Vad
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26064588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0102697(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP0102697A2 publication Critical patent/HUP0102697A2/hu
Publication of HUP0102697A3 publication Critical patent/HUP0102697A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány tárgya eljárás heterológ fehérjék vagy polipeptidekexpresszálására élesztőben, ahol a termeléshez használt transzformáltélesztő törzs tartalmaz egy expressziós vektort, amiben a kiindulásiklónozási lépésben használt antibiotikum rezisztencia gént in vitromódosítással működésképtenné tették az élesztő gazdaszervezettranszformálása előtt. A találmány tárgyát képezik továbbá az ilyeneljárásban használt DNS szekvenciák, expressziós vektorok éstranszformált élesztősejtek. Ó
HU0102697A 1998-07-16 1999-07-02 Method of making proteins in transformed yeast cells HUP0102697A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199800945 1998-07-16
DKPA199900754 1999-05-28
PCT/DK1999/000380 WO2000004172A1 (en) 1998-07-16 1999-07-02 Method of making proteins in transformed yeast cells

Publications (2)

Publication Number Publication Date
HUP0102697A2 true HUP0102697A2 (hu) 2001-11-28
HUP0102697A3 HUP0102697A3 (en) 2003-09-29

Family

ID=26064588

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102697A HUP0102697A3 (en) 1998-07-16 1999-07-02 Method of making proteins in transformed yeast cells

Country Status (16)

Country Link
EP (1) EP1097228B1 (hu)
JP (1) JP4668414B2 (hu)
KR (1) KR20010071929A (hu)
CN (1) CN1187451C (hu)
AT (1) ATE318919T1 (hu)
AU (1) AU4499399A (hu)
BR (1) BR9912106B1 (hu)
CA (1) CA2337635A1 (hu)
DE (1) DE69930118T2 (hu)
ES (1) ES2260917T3 (hu)
HU (1) HUP0102697A3 (hu)
IL (1) IL140403A0 (hu)
NO (1) NO20010246D0 (hu)
PL (1) PL201350B1 (hu)
RU (1) RU2238323C2 (hu)
WO (1) WO2000004172A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100783287B1 (ko) * 2006-08-09 2007-12-06 한국생명공학연구원 텔로미어 전사 비활성화에 관여하는 화합물의 동정을 위한균주의 제조
JP2016521701A (ja) 2013-06-07 2016-07-25 ノヴォ ノルディスク アー／エス 成熟インスリンポリペプチドを作製するための方法
WO2020106599A1 (en) * 2018-11-19 2020-05-28 Basf Se A recombinant yeast cell

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0635574B1 (en) * 1993-07-23 2003-04-23 Dsm N.V. Selection marker gene free recombinant strains, a method for obtaining them and the use of these strains
DE4428402A1 (de) * 1994-08-11 1996-02-15 Boehringer Mannheim Gmbh Gentherapeutisches Verfahren unter Verwendung von DNA-Vektoren ohne Selektionsmarker-Gen
JP4090090B2 (ja) * 1996-06-21 2008-05-28 サントリー株式会社 選択マーカー遺伝子を持たない形質転換体の作製方法
EP0814165B1 (en) * 1996-06-21 2003-04-09 Suntory Limited Method for constructing transformed yeast cells, that do not contain a selective marker gene

Also Published As

Publication number Publication date
KR20010071929A (ko) 2001-07-31
EP1097228B1 (en) 2006-03-01
NO20010246L (no) 2001-01-15
JP2002520061A (ja) 2002-07-09
ES2260917T3 (es) 2006-11-01
CA2337635A1 (en) 2000-01-27
WO2000004172A1 (en) 2000-01-27
JP4668414B2 (ja) 2011-04-13
ATE318919T1 (de) 2006-03-15
PL201350B1 (pl) 2009-04-30
HUP0102697A3 (en) 2003-09-29
DE69930118T2 (de) 2006-11-02
PL345584A1 (en) 2001-12-17
AU4499399A (en) 2000-02-07
EP1097228A1 (en) 2001-05-09
BR9912106A (pt) 2001-05-02
RU2238323C2 (ru) 2004-10-20
IL140403A0 (en) 2002-02-10
CN1187451C (zh) 2005-02-02
DE69930118D1 (de) 2006-04-27
BR9912106B1 (pt) 2012-09-04
CN1309712A (zh) 2001-08-22
NO20010246D0 (no) 2001-01-15

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees