HUP0002176A2 - Vakcinákban vagy diagnosztikai vizsgálatokban alkalmazható PRRSV-peptidszekvenciákat azonosító PRRSV-antigénhelyek - Google Patents

Vakcinákban vagy diagnosztikai vizsgálatokban alkalmazható PRRSV-peptidszekvenciákat azonosító PRRSV-antigénhelyek

Info

Publication number
HUP0002176A2
HUP0002176A2 HU0002176A HUP0002176A HUP0002176A2 HU P0002176 A2 HUP0002176 A2 HU P0002176A2 HU 0002176 A HU0002176 A HU 0002176A HU P0002176 A HUP0002176 A HU P0002176A HU P0002176 A2 HUP0002176 A2 HU P0002176A2
Authority
HU
Hungary
Prior art keywords
vaccines
peptides
antibodies
peptide sequences
diagnostic assays
Prior art date
Application number
HU0002176A
Other languages
English (en)
Inventor
Jan Langeveld
Janneke Meulenberg
Antonie Paul Van Nieuwstadt
Original Assignee
Stichting Dienst Landbouwkundig Onderzoek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Dienst Landbouwkundig Onderzoek filed Critical Stichting Dienst Landbouwkundig Onderzoek
Publication of HUP0002176A2 publication Critical patent/HUP0002176A2/hu
Publication of HUP0002176A3 publication Critical patent/HUP0002176A3/hu
Publication of HU228704B1 publication Critical patent/HU228704B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A találmány tárgyát a PRRSV GP4-protein neutralizációs helyénekmegfelelő aminosavszekvenciából származó aminosavszekvenciáttartalmazó, neutralizáló ellenanyagok termelődését kiváltó peptidekképezik, amelyek lehetnek legalább két különböző PRRSV-izolátummalreagáló ellenanyagok termelődését kiváltó peptidek, vagy legalább kétkülönböző PRRSV-izolátum megkülönböztetésére alkalmas ellenanyagoktermelődését kiváltó peptidek. A találmány tárgyát képezik továbbá aGP4-protein neutralizációs helyének megfelelő neutralizálóellenanyagokat indukáló immunológiai készítmények, vakcinák PRRS-fertőzés megelőzésére, a peptidekkel reagáló szintetikus ellenanyagok,továbbá diagnosztikai reagenskészletek, valamint alkalmazásaik. Atalálmány szerinti megoldás PRRS-vírusok vizsgálata területénalkalmazható. Ó
HU0002176A 1997-05-06 1998-05-05 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays HU228704B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201343 1997-05-06
PCT/NL1998/000251 WO1998050426A1 (en) 1997-05-06 1998-05-05 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays

Publications (3)

Publication Number Publication Date
HUP0002176A2 true HUP0002176A2 (hu) 2000-11-28
HUP0002176A3 HUP0002176A3 (en) 2001-09-28
HU228704B1 HU228704B1 (en) 2013-05-28

Family

ID=8228298

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002176A HU228704B1 (en) 1997-05-06 1998-05-05 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays

Country Status (21)

Country Link
US (1) US6495138B1 (hu)
EP (2) EP0980387B1 (hu)
JP (1) JP2000512313A (hu)
KR (1) KR100388257B1 (hu)
CN (1) CN1259141B (hu)
AT (1) ATE365746T1 (hu)
AU (1) AU754938B2 (hu)
BR (1) BR9809221A (hu)
CA (2) CA2703181C (hu)
CZ (1) CZ297371B6 (hu)
DE (1) DE69837992T2 (hu)
DK (1) DK0980387T3 (hu)
ES (1) ES2289781T3 (hu)
HU (1) HU228704B1 (hu)
ID (1) ID23399A (hu)
PL (1) PL197057B1 (hu)
PT (1) PT980387E (hu)
RU (1) RU2220978C2 (hu)
SK (1) SK286063B6 (hu)
UA (1) UA73915C2 (hu)
WO (1) WO1998050426A1 (hu)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
DE19850718C1 (de) * 1998-11-03 2000-05-18 Hildt Eberhardt Zellpermeabilität-vermittelndes Polypeptid
JP3961222B2 (ja) * 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Ｐｒｒｓｖワクチン
DK1183332T3 (da) 1999-04-22 2010-09-06 Us Agriculture Porcint Reproduktions- og Respirations Syndrom-vaccine baseret på isolere JA-142
MXPA03007751A (es) * 2001-03-09 2004-11-12 Boehringer Ingelheim Vetmed Cepas vivas atenuadas del virus prrs.
US7335361B2 (en) * 2003-06-09 2008-02-26 Animal Technology Institute Taiwan Fusion antigen used as vaccine
KR20070028547A (ko) 2004-06-18 2007-03-12 리전츠 오브 더 유니버스티 오브 미네소타 바이러스에 감염되고 백신접종된 생물의 동정
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
KR20130105750A (ko) * 2005-02-25 2013-09-25 아이덱스 래보러토리즈, 인코포레이티드 돼지 생식기 호흡기 증후군 바이러스에 대한 항체를 검출하기 위한 펩티드
CA2611820C (en) 2005-06-24 2015-10-06 Regents Of The University Of Minnesota Prrs viruses, infectious clones, mutants thereof, and methods of use
CN101495138B (zh) 2005-11-29 2014-01-08 衣阿华州立大学研究基金公司 猪繁殖与呼吸综合征病毒（prrsv）的保护性抗原决定子的鉴定及其用途
US20100227339A1 (en) 2005-12-02 2010-09-09 Iowa State University Research Foundation, Inc. Differential immunoassay for prrs vaccine antibody
CN102316895A (zh) * 2008-08-25 2012-01-11 贝林格尔.英格海姆维特梅迪卡有限公司 抗高致病性猪生殖与呼吸综合征(hp prrs)的疫苗
KR101101386B1 (ko) * 2008-12-04 2012-01-02 주식회사 바이오리쏘스 북미형 ｐｒｒｓｖ에 특이적인 면역원성 펩티드 및 그의 용도
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
US9132185B2 (en) 2010-06-02 2015-09-15 Virginia Tech Intellectual Properties, Inc. Modified live-attenuated vaccines (MLV) created by DNA shuffling against porcine reproductive and respiratory syndrome virus (PRRSV)
CN101885759B (zh) * 2010-06-25 2013-01-09 国家兽用生物制品工程技术研究中心 一种特异性结合猪繁殖与呼吸综合症病毒的多肽及其筛选方法和应用
SG192821A1 (en) 2011-02-17 2013-09-30 Boehringer Ingelheim Vetmed Commercial scale process for production of prrsv
WO2012110489A2 (en) 2011-02-17 2012-08-23 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
US9315781B2 (en) 2011-07-29 2016-04-19 Boehringer Ingelheim Vetmedica Gmbh Infectious CDNA clone of european PRRS virus and uses thereof
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
AU2011384799A1 (en) * 2011-12-30 2014-07-03 United Biomedical, Inc. Synthetic peptide-based marker vaccine and diagnostic system for effective control of porcine reproductive and respiratory syndrome (PRRS)
KR101430223B1 (ko) * 2012-10-09 2014-09-25 전북대학교산학협력단 면역유도능이 증가된 돼지생식기호흡기증후군 바이러스
CN103421817B (zh) * 2012-10-15 2016-01-13 华中农业大学 人工合成的猪繁殖与呼吸综合征病毒多表位基因及应用
CA2892948C (en) 2012-12-07 2022-09-20 The Board Of Trustees Of The University Of Illinois Porcine reproductive and respiratory syndrome virus compositions and uses thereof
CN103059142B (zh) * 2012-12-17 2015-02-25 重庆市畜牧科学院 猪圆环病毒的抗原和猪繁殖与呼吸综合征病毒的抗原的重组蛋白及其制备方法与应用
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
EP2804000A1 (en) * 2013-05-15 2014-11-19 Prionics AG Method for the detection and classification of PRRSV-infections in swine herds and diagnostic antigen compositions for such methods
CA2930042C (en) 2013-12-20 2022-06-21 Boehringer Ingelheim Vetmedica Gmbh Prrs virus variant, european prrs virus cdna clone, and uses thereof
JP6538071B2 (ja) 2014-03-21 2019-07-03 ニューテック・ベンチャーズ 非天然発生のブタ生殖器呼吸器症候群ウイルス（ｐｒｒｓｖ）及び使用する方法
AU2016282772B2 (en) 2015-06-23 2019-09-05 Boehringer Ingelheim Animal Health USA Inc. PRRSV minor protein-containing recombinant viral vectors and methods of making and use thereof
CN106442968B (zh) * 2016-09-21 2018-03-06 福建省农业科学院畜牧兽医研究所 猪繁殖与呼吸综合征血清学鉴别诊断试剂盒
CN109022613A (zh) * 2018-04-24 2018-12-18 上海申亚动物保健品阜阳有限公司 一种检测猪繁殖与呼吸综合征病毒的试剂盒及检测方法
KR102091279B1 (ko) * 2018-08-07 2020-03-20 대한민국 돼지 생식기 및 호흡기 증후군 바이러스 진단용 재조합 항원 단백질 및 이의 용도
KR102138287B1 (ko) * 2018-08-07 2020-07-29 대한민국 돼지 생식기 및 호흡기 증후군 바이러스 진단용 유전형별 재조합 항원 단백질 및 이의 용도
CN110894243B (zh) * 2019-12-16 2021-07-13 中国农业大学 一种猪蓝耳病毒嵌合抗原以及检测猪蓝耳病毒抗体的胶体金免疫层析试纸条
CN112458115B (zh) * 2020-10-21 2022-06-07 天津农学院 一种基因构建重组质粒pEGFP-GRE-GP5gB及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE118352T1 (de) 1991-06-06 1995-03-15 Stichting Centr Diergeneeskund Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits.
US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
ATE144144T1 (de) 1991-08-26 1996-11-15 James Edward Collins Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas)
MX9204885A (es) 1991-08-26 1994-05-31 Boehringer Animal Health Inc Composicion de vacuna que comprende virus del sindrome de infertilidad y respiratorio de los cerdos.
ATE131067T1 (de) 1991-10-14 1995-12-15 Akzo Nobel Nv Impfstoff gegen das fortpflanzungs- und atmungssyndrom bei schweinen (prrs) und diagnose.
US6251397B1 (en) * 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US5695766A (en) 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
EP0683816B1 (en) 1993-02-08 2000-11-02 Bayer Corporation Process for growing porcine reproductive and respiratory syndrome virus and its use in vaccines
ES2074950B1 (es) 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
GB2289279B (en) * 1994-05-13 1998-09-16 Iberica Cyanamid Diagnostic kits and vaccines containing recombinant PRRSV proteins
ATE329616T1 (de) * 1994-08-05 2006-07-15 Univ Minnesota Virale nukleotidsequenz vr-2332 und nutzungsverfahren
US5690940A (en) 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
ES2122921B1 (es) * 1996-12-30 1999-09-16 Inmunologia & Genetica Aplic Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.

Also Published As

Publication number Publication date
WO1998050426A1 (en) 1998-11-12
DE69837992D1 (de) 2007-08-09
JP2000512313A (ja) 2000-09-19
KR20010012337A (ko) 2001-02-15
CN1259141A (zh) 2000-07-05
ATE365746T1 (de) 2007-07-15
CA2703181A1 (en) 1998-11-12
PT980387E (pt) 2007-07-31
EP1882696A3 (en) 2008-03-05
CA2289980C (en) 2010-07-20
SK286063B6 (sk) 2008-02-05
CN1259141B (zh) 2013-03-27
ES2289781T3 (es) 2008-02-01
BR9809221A (pt) 2000-07-04
SK152699A3 (en) 2000-08-14
CZ297371B6 (cs) 2006-11-15
DK0980387T3 (da) 2007-10-22
HUP0002176A3 (en) 2001-09-28
CA2289980A1 (en) 1998-11-12
EP0980387B1 (en) 2007-06-27
PL197057B1 (pl) 2008-02-29
CZ9903932A3 (cs) 2000-10-11
AU7457198A (en) 1998-11-27
AU754938B2 (en) 2002-11-28
UA73915C2 (uk) 2005-10-17
PL336714A1 (en) 2000-07-03
HU228704B1 (en) 2013-05-28
ID23399A (id) 2000-04-20
CA2703181C (en) 2016-06-28
EP1882696A2 (en) 2008-01-30
US6495138B1 (en) 2002-12-17
EP0980387A1 (en) 2000-02-23
RU2220978C2 (ru) 2004-01-10
DE69837992T2 (de) 2008-03-20
KR100388257B1 (ko) 2003-06-19

Similar Documents

Publication Publication Date Title
HUP0002176A2 (hu) Vakcinákban vagy diagnosztikai vizsgálatokban alkalmazható PRRSV-peptidszekvenciákat azonosító PRRSV-antigénhelyek
CY1108299T1 (el) Πεπτιδια του ιου ανθρωπινης ανοσοανεπαρκειας (hiv), αντιγονα και συνθεσεις εμβολιου
AR038568A1 (es) Anticuerpos anti-a beta y su uso
HUP0303134A2 (hu) HIV-peptidek, antigének, vakcinakészítmények, immunológiai mérési reagenskészletek és eljárás HIV által indukált antitestek detektálására
ATE118352T1 (de) Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits.
ES2101388T3 (es) Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c.
PT97159A (pt) Processo para a preparacao de uma proteina do antigenio de superficie da hepatite b ou de um seu fragmento e processo para a preparacao de uma vacina
DK614987A (da) Syntetiske htlv-iii peptider, praeparater og anvendelser deraf
SE8703225D0 (sv) Monoclonal antibodies and peptides useful in treating and diagnosing hiv infections
ATE442439T1 (de) Melanoma antigene p15 und deren anwendung in diagnostischen und therapeutischen verfahren
ATE349533T1 (de) Zusammensetzung zur diagnose und behandlung von herpes simplex virusinfektionen
ATE134195T1 (de) Peptidfragmente von hiv
ATE128716T1 (de) Hiv-peptide und methoden für den nachweis von hiv.
ES2054769T3 (es) Polipeptidos hiv-2 recombinantes.
ATE109158T1 (de) Rubella-e1 und c peptide.
ATE346087T1 (de) Hepatitis e-virus aus dem schwein und dessen verwendungen
DE69934098D1 (de) Neues diagnostisches reagens und kit zur erkennung von rickettsiose
DE69017352D1 (de) An HIV relatierte Peptide.
DE69433787D1 (de) Von htlv-i und htlv-ii gp21 abgeleitete peptide zur diagnostischen verwendung
NO902491D0 (no) Proteiner, vaksiner og nukleinsyrer.
WO2002051865A3 (fr) Antigenes proteiques inducteurs d'anticorps neutralisant le virus vih
TH9844A (th) เพพไทด์ที่สัมพันธุ์ hiv
TH9844EX (th) เพพไทด์ที่สัมพันธุ์ hiv
EP0808846A3 (en) Peptides which react with antiboby representing the prognostic marker for HIV disease progression
BR0302029A (pt) Anticorpo ou um fragmento do mesmo, fragmento de um anticorpo, molécula de ácido nucleico, vetor, célula hospedeira, uso de um anticorpo ou um fragmento do mesmo, composto quìmico, péptìdeo, vacina, kit para estudar infecção por hiv in vivo ou in vitro, peptìdeo isolado, e, método para inibir a ligação de hiv a um co-receptor viral