CY1108299T1 - Πεπτιδια του ιου ανθρωπινης ανοσοανεπαρκειας (hiv), αντιγονα και συνθεσεις εμβολιου - Google Patents

Πεπτιδια του ιου ανθρωπινης ανοσοανεπαρκειας (hiv), αντιγονα και συνθεσεις εμβολιου

Info

Publication number
CY1108299T1
CY1108299T1 CY20081100922T CY081100922T CY1108299T1 CY 1108299 T1 CY1108299 T1 CY 1108299T1 CY 20081100922 T CY20081100922 T CY 20081100922T CY 081100922 T CY081100922 T CY 081100922T CY 1108299 T1 CY1108299 T1 CY 1108299T1
Authority
CY
Cyprus
Prior art keywords
hiv
peptides
antigens
vaccine compositions
immunodeficiency virus
Prior art date
Application number
CY20081100922T
Other languages
English (en)
Inventor
Birger Sörensen
Original Assignee
Bionor Immuno As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bionor Immuno As filed Critical Bionor Immuno As
Publication of CY1108299T1 publication Critical patent/CY1108299T1/el

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)

Abstract

Η παρούσα εφεύρεση περιλαμβάνει νέα τροποποιημένα πεπτίδια ικανά να επάγουν ανοσοαπόκριση ειδική ΗIV. Τα πεπτίδια βασίζονται σε διατηρούμενες περιοχές των πρωτεϊνών gag p24 του ΗIV. Περιγράφοντα αντιγόνα σε ελεύθερη μορφή ή μορφή φορέα-δεσμού που περιλαμβάνουν ένα τουλάχιστο από τα εν λόγω πεπτίδια, συνθέσεις εμβολίου που περιλαμβάνουν ένα τουλάχιστο από τα αντιγόνα, κιτ ανοσοδοκιμασίας και μια μέθοδο ανίχνευσης αντισωμάτων που επάγονται από HIV ή πεπτίδια ειδικά του HIV που χρησιμοποιούν τέτοια αντιγόνα.
CY20081100922T 1999-03-04 2008-08-28 Πεπτιδια του ιου ανθρωπινης ανοσοανεπαρκειας (hiv), αντιγονα και συνθεσεις εμβολιου CY1108299T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO19991078A NO311807B1 (no) 1999-03-04 1999-03-04 HIV-peptider, antigener, vaksinepreparater, immunoassay- testsett og en metode for påvisning av antistoffer fremkalt av HIV
EP00911492A EP1159298B1 (en) 1999-03-04 2000-03-02 Hiv peptides, antigens and vaccine compositions

Publications (1)

Publication Number Publication Date
CY1108299T1 true CY1108299T1 (el) 2014-02-12

Family

ID=19903050

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100922T CY1108299T1 (el) 1999-03-04 2008-08-28 Πεπτιδια του ιου ανθρωπινης ανοσοανεπαρκειας (hiv), αντιγονα και συνθεσεις εμβολιου

Country Status (23)

Country Link
US (4) US6706859B1 (el)
EP (1) EP1159298B1 (el)
JP (5) JP2002541069A (el)
CN (4) CN101328209A (el)
AT (1) ATE397014T1 (el)
AU (1) AU771827B2 (el)
BR (1) BR0008741A (el)
CA (1) CA2363947C (el)
CY (1) CY1108299T1 (el)
CZ (1) CZ300505B6 (el)
DE (1) DE60039036D1 (el)
DK (1) DK1159298T3 (el)
EA (1) EA004802B9 (el)
ES (1) ES2307496T4 (el)
HK (1) HK1044778B (el)
HU (1) HU229282B1 (el)
ID (1) ID30497A (el)
NO (1) NO311807B1 (el)
NZ (4) NZ514619A (el)
PT (1) PT1159298E (el)
SK (1) SK287382B6 (el)
WO (1) WO2000052040A1 (el)
ZA (1) ZA200107072B (el)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004503205A (ja) 2000-02-04 2004-02-05 デューク・ユニバーシティー ヒト免疫不全ウイルスワクチン
NO314587B1 (no) * 2000-09-04 2003-04-14 Bionor Immuno As HIV regulatoriske- og hjelpepeptider, antigener, vaksinepreparater, immunoassay testsett og en metode for påvisning av antistoffer fremkaltav HIV
NO314588B1 (no) * 2000-09-04 2003-04-14 Bionor Immuno As HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV
DK2004676T3 (en) 2006-03-10 2017-02-20 Peptcell Ltd PEPTIDES OF REGULATORY OR ACCESSORY PROTEINS OF HIV, COMPOSITIONS AND APPLICATION THEREOF
KR101701198B1 (ko) 2008-06-19 2017-02-01 배리에이션 바이오테크놀로지스 아이엔씨. 인플루엔자를 치료하기 위한 조성물 및 방법
BR112012000826B1 (pt) 2009-07-06 2022-07-26 Variation Biotechnologies Inc Método para a preparação de vesículas
WO2011005772A1 (en) 2009-07-06 2011-01-13 Variation Biotechnologies, Inc. Methods for preparing vesicles and formulations produced therefrom
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
AU2011276223C1 (en) 2010-07-06 2016-05-12 Variation Biotechnologies, Inc. Compositions and methods for treating influenza
EA025152B1 (ru) * 2010-12-02 2016-11-30 Бионор Иммуно Ас Конструкция пептидного каркаса
BR112013017939B1 (pt) 2011-01-13 2022-11-16 Variation Biotechnologies Inc Composição imunogênica liofilizada termoestável, uso e método para preparação da mesma
DK2691530T3 (en) 2011-06-10 2018-05-22 Univ Oregon Health & Science CMV GLYCOPROTEIN AND RECOMBINANT VECTORS
AU2012216792A1 (en) 2011-09-12 2013-03-28 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
EP2802353A4 (en) 2012-01-12 2015-12-02 Variation Biotechnologies Inc COMPOSITIONS AND METHOD FOR THE TREATMENT OF VIRUS INFECTIONS
US20150079077A1 (en) 2012-01-27 2015-03-19 Variation Biotechnologies, Inc. Methods and compositions for therapeutic agents
EP3967323A3 (en) 2012-06-06 2022-05-04 Bionor Immuno AS Hiv vaccine
NZ702146A (en) * 2012-06-06 2016-11-25 Bionor Immuno As Peptides derived from viral proteins for use as immunogens and dosage reactants
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
WO2015007337A1 (en) 2013-07-19 2015-01-22 Bionor Immuno As Method for the vaccination against hiv
EP3033106A1 (en) * 2013-08-14 2016-06-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Immunoadjuvant compositions and uses thereof
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
WO2015086738A2 (en) * 2013-12-11 2015-06-18 Bionor Immuno As Hiv vaccine
CA2936139A1 (en) 2014-01-27 2015-07-30 Bionor Immuno As Method for the vaccination against hiv
WO2015110659A1 (en) * 2014-01-27 2015-07-30 Bionor Immuno As Methods of immunization with a vaccine inducing a humoral immune response and with a vaccine inducing a cellular immune response
EP3099318A1 (en) * 2014-01-27 2016-12-07 Bionor Immuno AS Dosage regimen for hiv vaccine
PL3126373T3 (pl) 2014-04-03 2020-07-27 Amgen Inc. Sposób wytwarzania amg 416
JP2017523166A (ja) 2014-07-11 2017-08-17 ビオノール イミュノ エーエスBionor Immuno As ヒト免疫不全ウイルスi(hiv)の病理学的影響を減少及び/若しくは遅延させるか又は後天性免疫不全症候群(aids)を発症するリスクを低減させる方法
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US20180140694A1 (en) 2015-05-04 2018-05-24 Bionor Immuno As Dosage regimen for hiv vaccine

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62164696A (ja) 1986-01-06 1987-07-21 エフ.ホフマン ― ラ ロシュ アーゲー HTLV−3gag遺伝子の発現
US4925784A (en) 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
GB8629116D0 (en) 1986-12-05 1987-01-14 Hoffmann La Roche Env/gag polypeptides
DE3877294T2 (de) 1987-09-04 1993-05-06 Int Murex Tech Corp Festphasenimmunoassay fuer einen antikoerper und hierbei verwendete biologische produkte.
US4888290A (en) * 1987-11-06 1989-12-19 Coulter Corporation Monoclonal antibody specific to HIV antigens
EP0356007A3 (en) * 1988-07-22 1991-07-03 Medical Research Council Antigenic determinants
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
SE468168B (sv) 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
FR2703252B1 (fr) * 1993-03-31 1996-09-06 Fernand Narbey Torossian Complexe immunomodulateur anti SIDA.
AU7101294A (en) 1993-06-07 1995-01-03 Endocon, Inc. Implant stimulated cellular immunity
KR100235849B1 (ko) * 1993-10-19 1999-12-15 에가시라 구니오 HIV에 대한 면역응답을 유도할 수 있는 펩티드 및 그 펩티드를 함유하는 항 AIDS 예방, 치료제(Peptides Capable of Inducing Immune Response to HIV and Anti-AIDS Agent for Preventing and Curing AIDS)
FR2731013B1 (fr) * 1995-02-27 1997-05-16 Inst Nat Sante Rech Med Vih-1 de groupe o, fragments desdits virus, ainsi que leurs applications
JP3534417B2 (ja) * 1997-03-10 2004-06-07 ロシュ ダイアグノスティックス ゲーエムベーハー Hiv抗原及びhiv抗体の同時決定方法

Also Published As

Publication number Publication date
AU3335800A (en) 2000-09-21
PT1159298E (pt) 2008-09-04
ES2307496T4 (es) 2015-03-06
ES2307496T3 (es) 2008-12-01
JP5313998B2 (ja) 2013-10-09
EP1159298A1 (en) 2001-12-05
JP5814331B2 (ja) 2015-11-17
CN100387617C (zh) 2008-05-14
EA004802B1 (ru) 2004-08-26
WO2000052040A1 (en) 2000-09-08
CN1346367A (zh) 2002-04-24
ATE397014T1 (de) 2008-06-15
HUP0200265A2 (en) 2002-06-29
EA200100943A1 (ru) 2002-02-28
JP2013032386A (ja) 2013-02-14
BR0008741A (pt) 2002-01-08
CA2363947A1 (en) 2000-09-08
CA2363947C (en) 2008-05-20
JP2014043468A (ja) 2014-03-13
DE60039036D1 (de) 2008-07-10
ID30497A (id) 2001-12-13
JP5695010B2 (ja) 2015-04-01
NZ525753A (en) 2004-10-29
US7709004B2 (en) 2010-05-04
EP1159298B1 (en) 2008-05-28
NO311807B1 (no) 2002-01-28
SK12402001A3 (sk) 2002-02-05
US7709003B2 (en) 2010-05-04
CN101328209A (zh) 2008-12-24
US6706859B1 (en) 2004-03-16
JP5695012B2 (ja) 2015-04-01
JP2011074081A (ja) 2011-04-14
US7311915B2 (en) 2007-12-25
HK1044778B (zh) 2009-04-24
HU229282B1 (en) 2013-10-28
EA004802B9 (ru) 2015-03-31
HK1044778A1 (en) 2002-11-01
CZ20013195A3 (cs) 2002-02-13
NZ525751A (en) 2004-10-29
US20040259797A1 (en) 2004-12-23
JP2002541069A (ja) 2002-12-03
NO991078D0 (no) 1999-03-04
NZ514619A (en) 2003-10-31
SK287382B6 (sk) 2010-08-09
US20080107669A1 (en) 2008-05-08
ZA200107072B (en) 2002-11-27
NO991078L (no) 2000-09-05
US20080107670A1 (en) 2008-05-08
NZ525752A (en) 2004-10-29
CZ300505B6 (cs) 2009-06-03
DK1159298T3 (da) 2008-08-25
CN101328210A (zh) 2008-12-24
JP2013032384A (ja) 2013-02-14
AU771827B2 (en) 2004-04-01
CN101328208A (zh) 2008-12-24

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