ES2101388T3 - Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c. - Google Patents

Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c.

Info

Publication number
ES2101388T3
ES2101388T3 ES94108611T ES94108611T ES2101388T3 ES 2101388 T3 ES2101388 T3 ES 2101388T3 ES 94108611 T ES94108611 T ES 94108611T ES 94108611 T ES94108611 T ES 94108611T ES 2101388 T3 ES2101388 T3 ES 2101388T3
Authority
ES
Spain
Prior art keywords
detection
antibodies
hepatitis
virus
hcv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94108611T
Other languages
English (en)
Inventor
Robert J Deleys
Dirk Pollet
Geert Maertens
Heuverswyn Hugo Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26125651&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2101388(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Application granted granted Critical
Publication of ES2101388T3 publication Critical patent/ES2101388T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE PROPORCIONAN SECUENCIAS PEPTIDAS CAPACES DE MINIMIZAR PROTEINAS CODIFICADAS POR HCV PARA USO COMO REACTIVOS PARA DETECTAR LA EXPOSICION PREVIA A HCV DE SANGRE Y PRODUCTOS DE SANGRE. LOS PEPTIDOS SON AL MENOS 5 AMINOACIDOS LARGOS Y SE PUEDEN UTILIZAR EN DISTINTOS ENSAYOS ESPECIFICOS PARA DETECCION DE ANTICUERPOS DE HCV, PARA DETECCION DE ANTIGENOS HVC O COMO INMUNOGENOS.
ES94108611T 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c. Expired - Lifetime ES2101388T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90124241A EP0489968B1 (en) 1990-12-14 1990-12-14 Synthetic antigens for the detection of antibodies to hepatitis C virus
SG1996005024A SG47062A1 (en) 1990-12-14 1990-12-14 Synthetic antigens for the detection of antibodies to hepatitis virus

Publications (1)

Publication Number Publication Date
ES2101388T3 true ES2101388T3 (es) 1997-07-01

Family

ID=26125651

Family Applications (3)

Application Number Title Priority Date Filing Date
ES90124241T Expired - Lifetime ES2095852T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
ES94108611T Expired - Lifetime ES2101388T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c.
ES96201157T Expired - Lifetime ES2138784T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES90124241T Expired - Lifetime ES2095852T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES96201157T Expired - Lifetime ES2138784T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.

Country Status (18)

Country Link
US (1) US5922532A (es)
EP (3) EP0489968B1 (es)
JP (1) JP2995216B2 (es)
KR (3) KR0181344B1 (es)
AT (3) ATE149522T1 (es)
AU (1) AU652013B2 (es)
BR (1) BR9106220A (es)
CY (2) CY2043A (es)
DE (2) DE69030124T2 (es)
DK (3) DK0754704T3 (es)
ES (3) ES2095852T3 (es)
GR (3) GR3022089T3 (es)
HK (1) HK57597A (es)
HU (1) HU218357B (es)
IL (1) IL100158A (es)
NZ (1) NZ240964A (es)
SG (1) SG47062A1 (es)
WO (1) WO1992010514A2 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US6312889B1 (en) 1990-04-04 2001-11-06 Chiron Corporation Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
DK0770679T4 (da) * 1990-11-03 2010-05-10 Siemens Healthcare Diagnostics HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
WO1992012992A2 (en) * 1991-01-14 1992-08-06 James N. Gamble Institute Of Medical Research Basic structural immunogenic polypeptides having epitopes for hcv, antibodies, polynucleotide sequences, vaccines and methods
RO117329B1 (ro) * 1991-06-24 2002-01-30 Chiron Corp Emeryville Polipeptide care contin o secventa a virusului hepatitei c
DE4209215A1 (de) 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
US5811246A (en) * 1991-12-17 1998-09-22 The Research Foundation Of State University Of New York Process for immobilization onto the surfaces of ELISA plates of a compound carrier complex and for immunization
ZA928954B (en) * 1991-12-24 1993-05-19 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-A, non-B virus.
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
AU671623B2 (en) 1992-03-06 1996-09-05 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and biotinylated peptides used therein
EP1878797B1 (en) * 1992-07-16 2010-04-28 Advanced Life Science Institute, Inc Antigenic peptides for grouping hepatitis c virus, kit comprising the same and methods for its grouping using the same
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
CA2139100C (en) 1993-04-27 2009-06-23 Geert Maertens New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
IT1270941B (it) * 1993-05-12 1997-05-26 Sorin Biomedica Spa Peptidi di hcv e loro usi.
US7070790B1 (en) * 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
WO1996034013A1 (fr) * 1995-04-28 1996-10-31 Srl, Inc. Compose peptidique antigenique et methode de dosage immunologique
FR2775690B1 (fr) * 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
AU3714499A (en) * 1998-05-14 1999-11-29 Pasteur Merieux Serums Et Vaccins Hepatitis c virus mimotopes
US7052830B1 (en) * 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
AU2001272257A1 (en) * 2000-07-07 2002-01-21 Medmira Inc. Hcv mosaic antigen composition
AUPQ899400A0 (en) * 2000-07-26 2000-08-17 Csl Limited A method of stabilisation and compositions for use therein
JP4975600B2 (ja) * 2007-03-16 2012-07-11 シスメックス株式会社 Ｈｃｖ抗体測定用試薬キット及びｈｃｖ抗体測定方法
US20080227111A1 (en) 2007-03-16 2008-09-18 Sysmex Corporation Reagent kit and method for measuring hcv antibody
JP4975601B2 (ja) * 2007-03-16 2012-07-11 シスメックス株式会社 Ｈｃｖ抗体測定用試薬キット及びｈｃｖ抗体測定方法
ES2303496B1 (es) * 2008-02-21 2009-07-07 Fundacion Para El Estudio De Las Hepatitis Virales Metodo analitico perfeccionado para la deteccion de hepatitis c oculta, aplicaciones del mismo y su correspondiente kit de diagnostico.
US20100104555A1 (en) * 2008-10-24 2010-04-29 The Scripps Research Institute HCV neutralizing epitopes
FR2987836A1 (fr) * 2012-03-09 2013-09-13 Biomerieux Sa Peptides d'interference et procede de detection de microorganismes
CN114858907A (zh) * 2021-02-04 2022-08-05 北京毅新博创生物科技有限公司 用于诊断新冠肺炎的质谱模型的构建方法

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JP2702911B2 (ja) * 1985-09-11 1998-01-26 ユナイテツド・バイオメデイカル・インコ−ポレ−テツド 合成ペプチド、並びにそれを用いたエイズおよびプリ・エイズの検出方法
US4879212A (en) * 1986-04-02 1989-11-07 United Biomedical Inc. Peptide composition and method for the detection of antibodies to HTLV-III
US4749259A (en) * 1987-05-15 1988-06-07 Hughes Aircraft Company Liquid crystal image projection with multicolor prepolarizing system
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
HU216017B (hu) * 1987-11-18 1999-04-28 Chiron Corp. Eljárás HCV-1 polipeptidek, HCV-1 polinukleotidok, rekombináns vektorok és gazdasejtek, valamint immunesszé kit, hepatitis C vírusfertőzés elleni vakcinák, a fertőzés kimutatására szolgáló diagnosztikumok előállítására, és immunvizsgálati és vírustenyészt
HU225068B1 (en) * 1989-03-17 2006-05-29 Chiron Corp Process for producing diagnostics and vaccine of nanbh
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
EP0445801A3 (en) * 1990-03-08 1992-07-01 Kuraray Co., Ltd. Peptide and its use
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
HU217025B (hu) * 1990-04-04 1999-11-29 Chiron Corp. Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben
DK0527815T3 (da) * 1990-04-06 2000-11-06 Genelabs Tech Inc Hepatitis C-virus-epitop
AU635124B2 (en) * 1990-04-16 1993-03-11 United Biomedical Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and prevention thereof as vaccines
WO1992001714A1 (en) * 1990-07-24 1992-02-06 Yamanouchi Pharmaceutical Co., Ltd. Non-a non-b hepatitis virus antigen
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
JP3114731B2 (ja) * 1990-08-14 2000-12-04 国立感染症研究所長 Ｃ型肝炎ウイルス抗体検出用ペプチド抗原及びその使用方法
DE69133552C5 (de) * 1990-08-25 2008-01-10 F. Hoffmann-La Roche Ltd. Nicht-A, nicht-B Hepatitis Virus Antigen, und diagnostische Verfahren.
JP2949822B2 (ja) * 1990-10-03 1999-09-20 住友化学工業株式会社 熱可塑性樹脂組成物
DK0770679T4 (da) * 1990-11-03 2010-05-10 Siemens Healthcare Diagnostics HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf
CA2055149A1 (en) * 1990-11-08 1992-05-09 Hiroaki Okamoto Non-a, non-b hepatitis virus related antigen, antibody, detection systems, polynucleotides and polypeptides
KR920703640A (ko) * 1990-11-29 1992-12-18 테루카츄 아리마 비a비b형 간염 바이러스 항원 단백질
ES2066547T3 (es) * 1991-03-01 1995-03-01 Akzo Nobel Nv Peptidos, inmunoquimicamente reactivos con anticuerpos dirigidos contra virus de hepatitis no-a, no-b.
AU2068992A (en) * 1991-08-02 1993-02-04 Akzo N.V. Non-a, non-b peptide
ZA927243B (en) * 1991-10-07 1994-01-26 Akzo Nv Non-A, Non-B peptides
AU671623B2 (en) * 1992-03-06 1996-09-05 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and biotinylated peptides used therein

Also Published As

Publication number Publication date
JPH05503722A (ja) 1993-06-17
DK0489968T3 (da) 1997-03-24
WO1992010514A2 (en) 1992-06-25
WO1992010514A3 (en) 1992-08-20
CY2043A (en) 1998-02-20
DK0644202T3 (da) 1997-09-15
HU218357B (hu) 2000-08-28
KR0181344B1 (ko) 1999-04-01
IL100158A (en) 1998-02-22
GR3023664T3 (en) 1997-09-30
KR920703632A (ko) 1992-12-18
CY2053B1 (en) 1998-04-30
DE69030124T2 (de) 1997-09-18
DE69029092T2 (de) 1997-04-17
DK0754704T3 (da) 2000-04-03
US5922532A (en) 1999-07-13
ES2095852T3 (es) 1997-03-01
AU652013B2 (en) 1994-08-11
ATE185350T1 (de) 1999-10-15
ES2138784T3 (es) 2000-01-16
DE69029092D1 (de) 1996-12-12
NZ240964A (en) 1992-10-28
GR3022089T3 (en) 1997-03-31
KR0181343B1 (ko) 1999-04-01
HUT65930A (en) 1994-07-28
GR3032150T3 (en) 2000-04-27
JP2995216B2 (ja) 1999-12-27
HK57597A (en) 1997-05-09
SG47062A1 (en) 1998-03-20
EP0754704A2 (en) 1997-01-22
EP0489968A1 (en) 1992-06-17
ATE144993T1 (de) 1996-11-15
AU9068991A (en) 1992-07-08
DE69030124D1 (de) 1997-04-10
KR0181345B1 (ko) 1999-04-01
EP0754704B1 (en) 1999-10-06
EP0754704A3 (en) 1997-05-28
EP0644202B1 (en) 1997-03-05
HU9202645D0 (en) 1993-01-28
EP0644202A1 (en) 1995-03-22
ATE149522T1 (de) 1997-03-15
BR9106220A (pt) 1993-03-30
EP0489968B1 (en) 1996-11-06

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