HUP0000886A2 - Oxakarbazepin filmtabletták, eljárás előállításukra - Google Patents

Oxakarbazepin filmtabletták, eljárás előállításukra

Info

Publication number
HUP0000886A2
HUP0000886A2 HU0000886A HUP0000886A HUP0000886A2 HU P0000886 A2 HUP0000886 A2 HU P0000886A2 HU 0000886 A HU0000886 A HU 0000886A HU P0000886 A HUP0000886 A HU P0000886A HU P0000886 A2 HUP0000886 A2 HU P0000886A2
Authority
HU
Hungary
Prior art keywords
xacarbazepine
producing
coated tablets
film
oxacarbazepine
Prior art date
Application number
HU0000886A
Other languages
English (en)
Inventor
Burkhard Schlütermann
Original Assignee
Novartis Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4184588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0000886(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag. filed Critical Novartis Ag.
Publication of HUP0000886A2 publication Critical patent/HUP0000886A2/hu
Publication of HUP0000886A3 publication Critical patent/HUP0000886A3/hu
Publication of HU227807B1 publication Critical patent/HU227807B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

A találmány tárgya őxakarbazepinkészítmények, különösen filmtablettákés az előállításűkra szőlgáló eljárásők. A készítményeket az jellemzi,hőgy őlyan finőmra őrölt őxakarbazepint tartalmaznak, amelynek közepesszemcsemérete körülbelül 2-12 mm, előnyösen 4-12 mm, még előnyösebben4-10 mm, és maradéka 40 mm lyűkbőségű szitán legfeljebb 5 %. Azeljárást az jellemzi, hőgy az őxakarbazepinből és adőtt esetben egyébsegédanyagőkból egy közpőnti magőt alakítanak ki, és ezt egy hidrőfil,permeábilis bevőnattal látják el. Az őxakarbazepin görcsök kezelésérealkalmazható. ŕ
HU0000886A 1997-02-14 1998-02-12 Oxacarbazepine film-coated tablets, process for producing them HU227807B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH33197 1997-02-14
PCT/EP1998/000794 WO1998035681A1 (en) 1997-02-14 1998-02-12 Oxacarbazepine film-coated tablets

Publications (3)

Publication Number Publication Date
HUP0000886A2 true HUP0000886A2 (hu) 2000-09-28
HUP0000886A3 HUP0000886A3 (en) 2002-10-28
HU227807B1 HU227807B1 (en) 2012-03-28

Family

ID=4184588

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000886A HU227807B1 (en) 1997-02-14 1998-02-12 Oxacarbazepine film-coated tablets, process for producing them

Country Status (32)

Country Link
US (2) US20070036863A1 (hu)
EP (1) EP0966287B1 (hu)
JP (3) JP2000511935A (hu)
KR (3) KR19980071337A (hu)
CN (2) CN1170542C (hu)
AR (1) AR011142A1 (hu)
AT (1) ATE239481T1 (hu)
AU (1) AU738030B2 (hu)
BR (1) BR9807368A (hu)
CA (1) CA2277791C (hu)
CO (1) CO4920215A1 (hu)
CY (1) CY2480B1 (hu)
CZ (1) CZ298840B6 (hu)
DE (1) DE69814367T2 (hu)
DK (1) DK0966287T3 (hu)
ES (1) ES2199422T3 (hu)
HK (1) HK1024423A1 (hu)
HU (1) HU227807B1 (hu)
ID (1) ID22348A (hu)
MY (1) MY117582A (hu)
NO (1) NO327486B1 (hu)
NZ (1) NZ336946A (hu)
PE (1) PE58999A1 (hu)
PL (1) PL193332B1 (hu)
PT (1) PT966287E (hu)
RU (1) RU2201218C2 (hu)
SK (1) SK284503B6 (hu)
TR (1) TR199901804T2 (hu)
TW (1) TW529957B (hu)
UY (1) UY24888A1 (hu)
WO (1) WO1998035681A1 (hu)
ZA (1) ZA981205B (hu)

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CO4920215A1 (es) * 1997-02-14 2000-05-29 Novartis Ag Tabletas de oxacarbazepina recubiertas de una pelicula y metodo para la produccion de estas formulaciones
GB9925962D0 (en) * 1999-11-02 1999-12-29 Novartis Ag Organic compounds
US6368628B1 (en) * 2000-05-26 2002-04-09 Pharma Pass Llc Sustained release pharmaceutical composition free of food effect
AU2002348884A1 (en) 2001-12-21 2003-07-09 Pfizer Products Inc. Directly compressible formulations of azithromycin
GB0221956D0 (en) * 2002-09-20 2002-10-30 Novartis Ag Organic compounds
RU2369393C2 (ru) 2003-09-03 2009-10-10 Новартис Аг Применение окскарбазепина для лечения диабетической нейропатической боли и для улучшения сна
AR048318A1 (es) * 2004-03-22 2006-04-19 Novartis Ag Formulaciones de matriz orales que comprenden licarbazepina
AR048672A1 (es) * 2004-03-22 2006-05-17 Novartis Ag Tabletas de desintegracion que comprenden licarbazepina
US8367105B2 (en) 2004-11-10 2013-02-05 Teva Pharmaceutical Industries, Ltd. Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
DK1928427T3 (da) 2005-09-23 2010-03-08 Hoffmann La Roche Hidtil ukendt dosisformulering
ES2439736T3 (es) 2005-11-08 2014-01-24 Vertex Pharmaceuticals Incorporated Moduladores heterocíclicos de transportadores de casete de unión a ATP
AU2006313009B2 (en) * 2005-11-10 2013-10-24 Alphapharm Pty Ltd Process to control particle size
EP1951197A4 (en) * 2005-11-10 2011-12-21 Alphapharm Pty Ltd METHOD OF CHECKING THE PARTICLE SIZE
AU2007211210A1 (en) * 2006-01-31 2007-08-09 Teva Pharmaceutical Industries Ltd. Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution
WO2007089247A1 (en) * 2006-01-31 2007-08-09 Teva Pharmaceutical Industries Ltd. Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution
WO2007121523A1 (en) * 2006-04-21 2007-11-01 Alphapharm Pty Ltd Pharmaceutical compositions of oxcarbazepine with a median particle size of 15 to 30 microns
EP2359830B1 (en) * 2006-04-26 2012-09-19 Supernus Pharmaceuticals, Inc. Controlled released preparations of oxcarbazepine having sigmoidal release profile
WO2007122635A2 (en) 2006-04-26 2007-11-01 Astron Research Limited Controlled release formulation comprising anti-epileptic drugs
US20080138403A1 (en) * 2006-12-08 2008-06-12 Sun Pharmaceutical Industries Ltd. Pharmaceutical dosage forms of oxcarbazepine
EP2476418A1 (en) 2006-12-21 2012-07-18 Alphapharm Pty Ltd. Pharmaceutical compound and composition for use in treating type II diabetes comprising rosiglitazone in a specific particle size
GB0700773D0 (en) 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
EP1970056A1 (en) * 2007-03-15 2008-09-17 Polichem S.A. Time-specific delayed/pulsatile release dosage forms
EP2146699A2 (en) * 2007-05-23 2010-01-27 Ratiopharm GmbH Pharmaceutical compositions comprising oxcarbazepine
US8372431B2 (en) 2007-10-26 2013-02-12 Bial-Portela & C.A., S.A. Pharmaceutical composition comprising licarbazepine acetate
CN101910156B (zh) 2007-12-07 2013-12-04 沃泰克斯药物股份有限公司 3-(6-(1-(2,2-二氟苯并[d][1,3]间二氧杂环戊烯-5-基)环丙烷甲酰氨基)-3-甲基吡啶-2-基)苯甲酸的固体形式
DK3150198T3 (da) 2010-04-07 2021-11-01 Vertex Pharma Farmaceutiske sammensætninger af 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioxol-5-yl)-cyclopropancarboxamido)-3-methylpyriodin-2-yl)benzoesyre og indgivelse deraf
US10231932B2 (en) 2013-11-12 2019-03-19 Vertex Pharmaceuticals Incorporated Process of preparing pharmaceutical compositions for the treatment of CFTR mediated diseases
CN103735527B (zh) * 2013-12-24 2014-09-10 武汉人福药业有限责任公司 一种奥卡西平片剂及其制备方法
WO2018208242A1 (en) 2017-05-10 2018-11-15 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Formulation of deferasirox tablet for oral suspension composition with better processability

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Also Published As

Publication number Publication date
ZA981205B (en) 1998-08-14
WO1998035681A1 (en) 1998-08-20
NZ336946A (en) 2001-02-23
DE69814367T2 (de) 2004-02-26
CZ287999A3 (cs) 1999-11-17
CA2277791A1 (en) 1998-08-20
PT966287E (pt) 2003-09-30
PL334959A1 (en) 2000-03-27
CN1247471A (zh) 2000-03-15
TW529957B (en) 2003-05-01
SK284503B6 (sk) 2005-05-05
SK109899A3 (en) 2000-03-13
AU738030B2 (en) 2001-09-06
CO4920215A1 (es) 2000-05-29
AR011142A1 (es) 2000-08-02
AU6622298A (en) 1998-09-08
CY2480B1 (en) 2005-06-03
UY24888A1 (es) 2000-12-29
NO993919L (no) 1999-08-13
DK0966287T3 (da) 2003-08-25
EP0966287A1 (en) 1999-12-29
TR199901804T2 (xx) 1999-09-21
ID22348A (id) 1999-09-30
EP0966287B1 (en) 2003-05-07
NO993919D0 (no) 1999-08-13
HK1024423A1 (en) 2000-10-13
MY117582A (en) 2004-07-31
PE58999A1 (es) 1999-06-25
DE69814367D1 (de) 2003-06-12
CN1626093A (zh) 2005-06-15
KR20120079826A (ko) 2012-07-13
CZ298840B6 (cs) 2008-02-20
RU2201218C2 (ru) 2003-03-27
PL193332B1 (pl) 2007-02-28
US20080014269A1 (en) 2008-01-17
ES2199422T3 (es) 2004-02-16
HU227807B1 (en) 2012-03-28
JP2000511935A (ja) 2000-09-12
CN1170542C (zh) 2004-10-13
NO327486B1 (no) 2009-07-13
JP2010132694A (ja) 2010-06-17
KR20090037873A (ko) 2009-04-16
CA2277791C (en) 2008-11-18
KR19980071337A (ko) 1998-10-26
US20070036863A1 (en) 2007-02-15
HUP0000886A3 (en) 2002-10-28
JP2006077029A (ja) 2006-03-23
ATE239481T1 (de) 2003-05-15
BR9807368A (pt) 2000-03-14

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Legal Events

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MM4A Lapse of definitive patent protection due to non-payment of fees