HUP0000564A2 - Olajos szuszpenzió alakú gyógyászati készítmények - Google Patents
Olajos szuszpenzió alakú gyógyászati készítményekInfo
- Publication number
- HUP0000564A2 HUP0000564A2 HU0000564A HUP0000564A HUP0000564A2 HU P0000564 A2 HUP0000564 A2 HU P0000564A2 HU 0000564 A HU0000564 A HU 0000564A HU P0000564 A HUP0000564 A HU P0000564A HU P0000564 A2 HUP0000564 A2 HU P0000564A2
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical composition
- oil suspension
- ceftiofur
- contain
- formula
- Prior art date
Links
- 239000012053 oil suspension Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- KEQFDTJEEQKVLM-JUODUXDSSA-N (6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydron;chloride Chemical class Cl.S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC(=O)C1=CC=CO1 KEQFDTJEEQKVLM-JUODUXDSSA-N 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 229960005229 ceftiofur Drugs 0.000 abstract 1
- ZBHXIWJRIFEVQY-IHMPYVIRSA-N ceftiofur Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC(=O)C1=CC=CO1 ZBHXIWJRIFEVQY-IHMPYVIRSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A találmány gyógyszerkészítményekre vonatkozik, amelyek gyógyszerhatóanyagok olajos szuszpenziójában kis mennyiségű vizet tartalmaznak,pl. a (II) képletű ceftiofur, különösen a ceftiofur hid- roklorid sójaesetében. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/806,584 US5736151A (en) | 1996-12-09 | 1996-12-09 | Antibiotic oil suspensions |
PCT/US1997/021401 WO1998025621A1 (en) | 1996-12-09 | 1997-12-03 | Improved pharmaceutical compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0000564A2 true HUP0000564A2 (hu) | 2000-10-28 |
HUP0000564A3 HUP0000564A3 (en) | 2001-01-29 |
Family
ID=25194373
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0000564A HUP0000564A3 (en) | 1996-12-09 | 1997-12-03 | Pharmaceutical composition in form of oil suspension |
Country Status (22)
Country | Link |
---|---|
US (1) | US5736151A (hu) |
EP (1) | EP0941095B1 (hu) |
JP (1) | JP2001505910A (hu) |
KR (1) | KR100544248B1 (hu) |
CN (1) | CN100413506C (hu) |
AT (1) | ATE264681T1 (hu) |
AU (1) | AU746666B2 (hu) |
BR (1) | BR9714967B1 (hu) |
CA (1) | CA2269682C (hu) |
CZ (1) | CZ297632B6 (hu) |
DE (1) | DE69728783T2 (hu) |
DK (1) | DK0941095T3 (hu) |
ES (1) | ES2218705T3 (hu) |
FI (1) | FI991302A0 (hu) |
HK (1) | HK1023292A1 (hu) |
HU (1) | HUP0000564A3 (hu) |
NO (1) | NO325475B1 (hu) |
NZ (1) | NZ336183A (hu) |
PL (1) | PL190662B1 (hu) |
PT (1) | PT941095E (hu) |
SK (1) | SK72399A3 (hu) |
WO (1) | WO1998025621A1 (hu) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7829100B2 (en) * | 2000-09-12 | 2010-11-09 | Teagarden Dirk L | Pharmaceutical composition having modified carrier |
CA2416566C (en) * | 2000-09-12 | 2011-05-31 | Pharmacia & Upjohn Company | Depot formulation comprising ceftiofur and peroxidized natural oil |
KR100423895B1 (ko) * | 2001-02-19 | 2004-03-24 | 주식회사 엘지생명과학 | 셉티오퍼 하이드로클로라이드의 현탁제 조성물 |
US20040022815A1 (en) * | 2002-08-05 | 2004-02-05 | Orchid Health Care | Novel pharmaceutical composition of ceftiofur |
AU2002328168B2 (en) * | 2002-08-07 | 2008-08-21 | Merial Ltd. | Novel pharmaceutical composition of ceftiofur |
KR20040015622A (ko) * | 2002-08-13 | 2004-02-19 | 대한뉴팜(주) | 세프티오푸르나트륨을 활성성분으로 함유하는 현탁주사액조성물 |
US7659061B2 (en) * | 2002-11-19 | 2010-02-09 | Pharmacia & Upjohn Company | Pharmaceutical compositions having a modified vehicle |
US7842791B2 (en) * | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
KR100717433B1 (ko) * | 2003-03-20 | 2007-05-14 | 파마시아 코포레이션 | 소염제의 분산성 배합물 |
US20040214753A1 (en) * | 2003-03-20 | 2004-10-28 | Britten Nancy Jean | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
WO2005009472A2 (en) * | 2003-07-31 | 2005-02-03 | Pharmacia & Upjohn Company Llc | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
WO2006008640A1 (en) * | 2004-07-15 | 2006-01-26 | Pharmacia & Upjohn Company Llc | Non-aqueous suspension containing a drug having an unpleasant taste |
CZ300424B6 (cs) * | 2006-06-20 | 2009-05-13 | Pliva - Lachema A. S. | Farmaceutická kompozice pro perorální podání |
CZ300590B6 (cs) * | 2006-06-20 | 2009-06-24 | Pliva - Lachema A. S. | Farmaceutická kompozice pro injekcní podání |
CN101610754A (zh) * | 2007-02-16 | 2009-12-23 | Aska制药株式会社 | 含有微粒油性混悬液的药物组合物 |
CN101406447B (zh) * | 2007-10-12 | 2010-08-25 | 河南农业大学 | 复方头孢噻呋油混悬注射液制备工艺 |
US20100087481A1 (en) * | 2008-10-03 | 2010-04-08 | Lee Kathleen M | Oral pharmaceutical formulations for antidiabetic compounds |
KR101748890B1 (ko) * | 2008-11-19 | 2017-06-19 | 메리얼 인코포레이티드 | 세프티오퍼 및 케토프로펜 또는 세프티오퍼 및 벤질 알코올을 포함하는 제형 |
HUE046427T2 (hu) | 2012-07-17 | 2020-03-30 | Bayer New Zealand Ltd | Injektálható antibiotikus készítmények és azok alkalmazása |
FR3000392B1 (fr) | 2012-12-27 | 2015-03-27 | Virbac | Nouvelles compositions pharmaceutiques veterinaires et leur procede de preparation |
CN106456704A (zh) | 2014-04-16 | 2017-02-22 | Veyx-药物有限公司 | 兽药组合物和其应用 |
EP3267994A4 (en) | 2015-03-09 | 2018-10-31 | Intekrin Therapeutics, Inc. | Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy |
WO2018071810A1 (en) | 2016-10-13 | 2018-04-19 | RhinoNase, Inc. | Antibiotic compositions for nasal irrigation and methods |
WO2018187350A1 (en) | 2017-04-03 | 2018-10-11 | Coherus Biosciences Inc. | PPARγ AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY |
CN113209015A (zh) * | 2020-01-21 | 2021-08-06 | 江西邦诚动物药业有限公司 | 长效盐酸头孢噻呋混悬注射液及其制备工艺 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB914894A (en) * | 1960-08-12 | 1963-01-09 | Beecham Res Lab | Injectable pharmaceutical media |
NL260648A (hu) * | 1961-01-31 | |||
US3996355A (en) * | 1975-01-02 | 1976-12-07 | American Home Products Corporation | Permanent suspension pharmaceutical dosage form |
FR2479229B1 (fr) * | 1980-03-26 | 1986-01-17 | Clin Midy | Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives |
US4902683A (en) * | 1984-10-25 | 1990-02-20 | The Upjohn Company | Crystalline cephalosporin hydrohalide salts |
EP0233255B1 (en) * | 1985-08-12 | 1996-05-29 | The Upjohn Company | Conversion of cephalosporin hydrohalide salt to alkali metal salt |
DE3887691T2 (de) * | 1987-11-10 | 1994-06-09 | Upjohn Co | Cephalosporin-antibiotika. |
US5223496A (en) * | 1987-11-10 | 1993-06-29 | The Upjohn Company | Cephalosporin antibiotics |
US4877782A (en) * | 1988-02-16 | 1989-10-31 | The Upjohn Company | Zinc ceftiofur complexes |
AU639004B2 (en) * | 1989-06-13 | 1993-07-15 | Abbott Laboratories | Anhydrous oil-based liquid suspension for delivering a medicament |
ATE202109T1 (de) * | 1993-03-12 | 2001-06-15 | Upjohn Co | Kristallines ceftiofur (freie säure) |
-
1996
- 1996-12-09 US US08/806,584 patent/US5736151A/en not_active Expired - Lifetime
-
1997
- 1997-12-03 KR KR1019997005069A patent/KR100544248B1/ko not_active IP Right Cessation
- 1997-12-03 NZ NZ336183A patent/NZ336183A/xx not_active IP Right Cessation
- 1997-12-03 CN CNB971801495A patent/CN100413506C/zh not_active Expired - Lifetime
- 1997-12-03 SK SK723-99A patent/SK72399A3/sk unknown
- 1997-12-03 DE DE69728783T patent/DE69728783T2/de not_active Revoked
- 1997-12-03 WO PCT/US1997/021401 patent/WO1998025621A1/en active IP Right Grant
- 1997-12-03 BR BRPI9714967-5A patent/BR9714967B1/pt not_active IP Right Cessation
- 1997-12-03 AT AT97948461T patent/ATE264681T1/de not_active IP Right Cessation
- 1997-12-03 EP EP97948461A patent/EP0941095B1/en not_active Revoked
- 1997-12-03 CA CA002269682A patent/CA2269682C/en not_active Expired - Lifetime
- 1997-12-03 ES ES97948461T patent/ES2218705T3/es not_active Expired - Lifetime
- 1997-12-03 PL PL97333790A patent/PL190662B1/pl not_active IP Right Cessation
- 1997-12-03 JP JP52669998A patent/JP2001505910A/ja active Pending
- 1997-12-03 PT PT97948461T patent/PT941095E/pt unknown
- 1997-12-03 AU AU54529/98A patent/AU746666B2/en not_active Expired
- 1997-12-03 HU HU0000564A patent/HUP0000564A3/hu unknown
- 1997-12-03 DK DK97948461T patent/DK0941095T3/da active
- 1997-12-03 CZ CZ0202599A patent/CZ297632B6/cs not_active IP Right Cessation
-
1999
- 1999-06-08 FI FI991302A patent/FI991302A0/fi not_active Application Discontinuation
- 1999-06-08 NO NO19992780A patent/NO325475B1/no not_active IP Right Cessation
-
2000
- 2000-04-28 HK HK00102581.1A patent/HK1023292A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI991302A (fi) | 1999-06-08 |
PT941095E (pt) | 2004-08-31 |
CA2269682A1 (en) | 1998-06-18 |
ES2218705T3 (es) | 2004-11-16 |
NO992780D0 (no) | 1999-06-08 |
NZ336183A (en) | 2000-12-22 |
ATE264681T1 (de) | 2004-05-15 |
BR9714967B1 (pt) | 2010-06-29 |
AU5452998A (en) | 1998-07-03 |
WO1998025621A1 (en) | 1998-06-18 |
US5736151A (en) | 1998-04-07 |
DK0941095T3 (da) | 2004-08-02 |
PL190662B1 (pl) | 2005-12-30 |
CA2269682C (en) | 2009-04-14 |
DE69728783T2 (de) | 2005-03-31 |
KR20000069360A (ko) | 2000-11-25 |
NO992780L (no) | 1999-06-08 |
EP0941095A1 (en) | 1999-09-15 |
CN1238690A (zh) | 1999-12-15 |
BR9714967A (pt) | 2001-10-30 |
CZ297632B6 (cs) | 2007-02-14 |
DE69728783D1 (de) | 2004-05-27 |
CZ202599A3 (cs) | 1999-09-15 |
FI991302A0 (fi) | 1999-06-08 |
AU746666B2 (en) | 2002-05-02 |
NO325475B1 (no) | 2008-05-13 |
KR100544248B1 (ko) | 2006-01-23 |
HUP0000564A3 (en) | 2001-01-29 |
CN100413506C (zh) | 2008-08-27 |
SK72399A3 (en) | 2000-05-16 |
EP0941095B1 (en) | 2004-04-21 |
JP2001505910A (ja) | 2001-05-08 |
HK1023292A1 (en) | 2000-09-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |