HUE060878T2 - Anti-transztiretin antitestek - Google Patents

Anti-transztiretin antitestek

Info

Publication number
HUE060878T2
HUE060878T2 HUE16702812A HUE16702812A HUE060878T2 HU E060878 T2 HUE060878 T2 HU E060878T2 HU E16702812 A HUE16702812 A HU E16702812A HU E16702812 A HUE16702812 A HU E16702812A HU E060878 T2 HUE060878 T2 HU E060878T2
Authority
HU
Hungary
Prior art keywords
transthyretin antibodies
transthyretin
antibodies
Prior art date
Application number
HUE16702812A
Other languages
English (en)
Hungarian (hu)
Inventor
Yue Liu
Tarlochan S Nijjar
Avijit Chakrabartty
Jeffrey Higaki
Original Assignee
Prothena Biosciences Ltd
Univ Health Network
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prothena Biosciences Ltd, Univ Health Network filed Critical Prothena Biosciences Ltd
Publication of HUE060878T2 publication Critical patent/HUE060878T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HUE16702812A 2015-01-28 2016-01-28 Anti-transztiretin antitestek HUE060878T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562109002P 2015-01-28 2015-01-28
US201562266556P 2015-12-11 2015-12-11

Publications (1)

Publication Number Publication Date
HUE060878T2 true HUE060878T2 (hu) 2023-04-28

Family

ID=55299694

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16702812A HUE060878T2 (hu) 2015-01-28 2016-01-28 Anti-transztiretin antitestek

Country Status (31)

Country Link
US (1) US20160251418A1 (enExample)
EP (2) EP3250592B1 (enExample)
JP (2) JP6748086B2 (enExample)
KR (2) KR102677203B1 (enExample)
CN (1) CN107406499B (enExample)
AU (1) AU2016210888C1 (enExample)
CA (1) CA2974912A1 (enExample)
CL (2) CL2017001924A1 (enExample)
CO (1) CO2017008476A2 (enExample)
CU (1) CU24480B1 (enExample)
DK (1) DK3250592T3 (enExample)
EA (1) EA036080B1 (enExample)
ES (1) ES2934656T3 (enExample)
FI (1) FI3250592T3 (enExample)
HR (1) HRP20221538T1 (enExample)
HU (1) HUE060878T2 (enExample)
IL (1) IL253633B (enExample)
LT (1) LT3250592T (enExample)
MX (1) MX394170B (enExample)
PE (1) PE20180217A1 (enExample)
PH (1) PH12017501318B1 (enExample)
PL (1) PL3250592T3 (enExample)
PT (1) PT3250592T (enExample)
RS (1) RS63906B1 (enExample)
SA (1) SA517382002B1 (enExample)
SG (2) SG10202101763VA (enExample)
SI (1) SI3250592T1 (enExample)
TW (2) TWI786505B (enExample)
UA (1) UA122142C2 (enExample)
WO (1) WO2016120810A1 (enExample)
ZA (1) ZA201705663B (enExample)

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US9879080B2 (en) 2015-01-28 2018-01-30 Prothena Biosciences Limited Anti-transthyretin antibodies
US10633433B2 (en) 2015-01-28 2020-04-28 Prothena Biosciences Limited Anti-transthyretin antibodies
US10464999B2 (en) 2015-01-28 2019-11-05 Prothena Biosciences Limited Anti-transthyretin antibodies
EP3478714A2 (en) * 2016-07-02 2019-05-08 Prothena Biosciences Limited Anti-transthyretin antibodies
SG11202002489YA (en) 2017-10-06 2020-04-29 Prothena Biosciences Ltd Anti-transthyretin antibodies
KR102581734B1 (ko) * 2017-10-06 2023-09-22 네오토프 뉴로사이언스 리미티드 트랜스타이레틴의 검출 방법
MA51223A (fr) 2017-11-29 2020-10-07 Prothena Biosciences Ltd Formulation lyophilisée d'un anticorps monoclonal contre la transthyrétine
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Also Published As

Publication number Publication date
JP2018506277A (ja) 2018-03-08
HRP20221538T1 (hr) 2023-03-03
ZA201705663B (en) 2018-08-29
TWI786505B (zh) 2022-12-11
JP7028923B2 (ja) 2022-03-02
PH12017501318A1 (en) 2018-02-05
PE20180217A1 (es) 2018-01-31
CL2017001924A1 (es) 2018-04-27
RS63906B1 (sr) 2023-02-28
EP4134379A1 (en) 2023-02-15
PL3250592T3 (pl) 2023-06-19
ES2934656T3 (es) 2023-02-23
TW202124436A (zh) 2021-07-01
KR20230156164A (ko) 2023-11-13
PT3250592T (pt) 2022-12-28
WO2016120810A1 (en) 2016-08-04
NZ733896A (en) 2024-11-29
CU20170097A7 (es) 2018-03-13
BR112017016330A2 (en) 2018-04-03
CO2017008476A2 (es) 2018-01-16
DK3250592T3 (en) 2023-01-09
JP2020185009A (ja) 2020-11-19
PH12017501318B1 (en) 2018-02-05
MX394170B (es) 2025-03-24
CN107406499A (zh) 2017-11-28
CA2974912A1 (en) 2016-08-04
EP3250592B1 (en) 2022-10-05
MX2017009806A (es) 2018-08-15
SI3250592T1 (sl) 2023-03-31
UA122142C2 (uk) 2020-09-25
CL2022003027A1 (es) 2023-06-09
IL253633B (en) 2021-06-30
JP6748086B2 (ja) 2020-09-02
EA201791712A1 (ru) 2017-12-29
LT3250592T (lt) 2023-02-10
US20160251418A1 (en) 2016-09-01
AU2016210888A1 (en) 2017-08-10
CU24480B1 (es) 2020-03-04
EA036080B1 (ru) 2020-09-23
SA517382002B1 (ar) 2021-11-25
TW201632554A (zh) 2016-09-16
CN107406499B (zh) 2021-10-22
FI3250592T3 (fi) 2023-01-13
EP3250592A1 (en) 2017-12-06
IL253633A0 (en) 2017-09-28
KR20170106469A (ko) 2017-09-20
AU2016210888B2 (en) 2021-11-04
AU2016210888C1 (en) 2022-06-02
SG11201706124VA (en) 2017-08-30
KR102598180B1 (ko) 2023-11-03
SG10202101763VA (en) 2021-04-29
KR102677203B1 (ko) 2024-06-20
TWI718122B (zh) 2021-02-11

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