Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
  • A61K31/7088—Compounds having three or more nucleosides or nucleotides
  • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
  • A61K31/7088—Compounds having three or more nucleosides or nucleotides
  • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
  • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
  • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
  • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
  • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
• • C—CHEMISTRY; METALLURGY
  • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
  • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
  • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
  • C12N15/09—Recombinant DNA-technology
  • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
  • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
• • C—CHEMISTRY; METALLURGY
  • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
  • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
  • C12N2310/00—Structure or type of the nucleic acid
  • C12N2310/10—Type of nucleic acid
  • C12N2310/11—Antisense
  • C12N2310/111—Antisense spanning the whole gene, or a large part of it

Landscapes

• Health & Medical Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Engineering & Computer Science (AREA)
• General Health & Medical Sciences (AREA)
• Molecular Biology (AREA)
• Bioinformatics & Cheminformatics (AREA)
• Pharmacology & Pharmacy (AREA)
• Animal Behavior & Ethology (AREA)
• Medicinal Chemistry (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Epidemiology (AREA)
• Biochemistry (AREA)
• Genetics & Genomics (AREA)
• Organic Chemistry (AREA)
• Proteomics, Peptides & Aminoacids (AREA)
• Biomedical Technology (AREA)
• Wood Science & Technology (AREA)
• Biotechnology (AREA)
• General Engineering & Computer Science (AREA)
• Zoology (AREA)
• Orthopedic Medicine & Surgery (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
• General Chemical & Material Sciences (AREA)
• Neurology (AREA)
• Physical Education & Sports Medicine (AREA)
• Physics & Mathematics (AREA)
• Microbiology (AREA)
• Biophysics (AREA)
• Plant Pathology (AREA)
• Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
• Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
• Medicinal Preparation (AREA)
• Peptides Or Proteins (AREA)

Applications Claiming Priority (4)

Publications (1)

Family

ID=61006315

Family Applications (1)

Country Status (27)

Families Citing this family (22)

Family Cites Families (177)

• 2017
  • 2017-12-13 KR KR1020197020418A patent/KR102552428B1/ko active Active
  • 2017-12-13 MX MX2019006882A patent/MX2019006882A/es unknown
  • 2017-12-13 HU HUE17832401A patent/HUE059843T2/hu unknown
  • 2017-12-13 SG SG10202012839TA patent/SG10202012839TA/en unknown
  • 2017-12-13 CN CN201780086301.2A patent/CN110290812B/zh active Active
  • 2017-12-13 MY MYPI2019003425A patent/MY195801A/en unknown
  • 2017-12-13 LT LTEPPCT/US2017/066222T patent/LT3554553T/lt unknown
  • 2017-12-13 AU AU2017382723A patent/AU2017382723B2/en active Active
  • 2017-12-13 PT PT178324018T patent/PT3554553T/pt unknown
  • 2017-12-13 JP JP2019531378A patent/JP7118063B2/ja active Active
  • 2017-12-13 RS RS20220837A patent/RS63610B1/sr unknown
  • 2017-12-13 EP EP17832401.8A patent/EP3554553B1/en active Active
  • 2017-12-13 CA CA3046793A patent/CA3046793A1/en active Pending
  • 2017-12-13 ES ES17832401T patent/ES2927079T3/es active Active
  • 2017-12-13 HR HRP20220943TT patent/HRP20220943T1/hr unknown
  • 2017-12-13 PL PL17832401.8T patent/PL3554553T3/pl unknown
  • 2017-12-13 WO PCT/US2017/066222 patent/WO2018118599A1/en not_active Ceased
  • 2017-12-13 US US15/841,261 patent/US10888578B2/en active Active
  • 2017-12-13 NZ NZ755416A patent/NZ755416A/en unknown
  • 2017-12-13 DK DK17832401.8T patent/DK3554553T3/da active
  • 2017-12-13 SM SM20220366T patent/SMT202200366T1/it unknown
  • 2017-12-13 MD MDE20191207T patent/MD3554553T2/ro unknown
  • 2017-12-13 KR KR1020237022506A patent/KR102810425B1/ko active Active
  • 2017-12-18 TW TW106144431A patent/TWI760402B/zh active
• 2019
  • 2019-06-11 IL IL267244A patent/IL267244B/en unknown
  • 2019-06-17 SA SA519402154A patent/SA519402154B1/ar unknown
  • 2019-06-24 ZA ZA2019/04092A patent/ZA201904092B/en unknown
  • 2019-07-10 CO CONC2019/0007397A patent/CO2019007397A2/es unknown
• 2020
  • 2020-11-19 US US16/952,514 patent/US20210169919A1/en not_active Abandoned
  • 2020-12-07 JP JP2020202518A patent/JP2021045160A/ja not_active Withdrawn
• 2021
  • 2021-10-06 IL IL287047A patent/IL287047A/en unknown
• 2022
  • 2022-05-04 US US17/736,148 patent/US11642364B2/en active Active
• 2023
  • 2023-03-09 US US18/181,271 patent/US20230381216A1/en active Pending
  • 2023-08-24 JP JP2023136250A patent/JP7691462B2/ja active Active

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