HUE049501T2 - Nitazoxanidot tartalmazó szabályozott felszabadulású gyógyszerkészítmény - Google Patents

Nitazoxanidot tartalmazó szabályozott felszabadulású gyógyszerkészítmény

Info

Publication number
HUE049501T2
HUE049501T2 HUE10741758A HUE10741758A HUE049501T2 HU E049501 T2 HUE049501 T2 HU E049501T2 HU E10741758 A HUE10741758 A HU E10741758A HU E10741758 A HUE10741758 A HU E10741758A HU E049501 T2 HUE049501 T2 HU E049501T2
Authority
HU
Hungary
Prior art keywords
controlled release
release formulation
formulation containing
containing nitazoxanide
nitazoxanide
Prior art date
Application number
HUE10741758A
Other languages
English (en)
Hungarian (hu)
Inventor
Jean-Francois Rossignol
Marc Ayers
Original Assignee
Romark Laboratories Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romark Laboratories Lc filed Critical Romark Laboratories Lc
Publication of HUE049501T2 publication Critical patent/HUE049501T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HUE10741758A 2009-02-13 2010-02-12 Nitazoxanidot tartalmazó szabályozott felszabadulású gyógyszerkészítmény HUE049501T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20228509P 2009-02-13 2009-02-13

Publications (1)

Publication Number Publication Date
HUE049501T2 true HUE049501T2 (hu) 2020-09-28

Family

ID=42560126

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE10741758A HUE049501T2 (hu) 2009-02-13 2010-02-12 Nitazoxanidot tartalmazó szabályozott felszabadulású gyógyszerkészítmény

Country Status (23)

Country Link
US (5) US8524278B2 (enExample)
EP (1) EP2395840B1 (enExample)
JP (3) JP5726766B2 (enExample)
KR (1) KR101697800B1 (enExample)
CN (2) CN107260695A (enExample)
AU (3) AU2010213678B2 (enExample)
BR (1) BRPI1007945C8 (enExample)
CA (1) CA2752233C (enExample)
CO (1) CO6501159A2 (enExample)
CY (1) CY1123162T1 (enExample)
DK (1) DK2395840T3 (enExample)
EA (1) EA029018B1 (enExample)
ES (1) ES2797493T3 (enExample)
HR (1) HRP20201055T1 (enExample)
HU (1) HUE049501T2 (enExample)
IL (1) IL214624A0 (enExample)
LT (1) LT2395840T (enExample)
MX (2) MX381895B (enExample)
PL (1) PL2395840T3 (enExample)
PT (1) PT2395840T (enExample)
SI (1) SI2395840T1 (enExample)
UA (1) UA107564C2 (enExample)
WO (1) WO2010093854A1 (enExample)

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JP6633092B2 (ja) 2014-11-11 2020-01-22 ロマーク ラボラトリーズ,リミティド カンパニー チゾキサニド、その類似体又は塩のプロドラッグを用いる組成物及び治療方法
HK1250945A1 (zh) 2016-03-31 2019-01-18 罗马克实验室有限公司 用於治疗病毒性感染的噻唑化物化合物
IL262186B2 (en) * 2016-04-11 2023-10-01 Genfit Synergistic combinations of nitazoxanide (ntz) compounds and statins
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WO2018230713A1 (ja) * 2017-06-16 2018-12-20 学校法人同志社 カスパーゼ阻害活性を有する化合物、これらの化合物を含む、角膜内皮の症状、障害または疾患を治療または予防するための医薬およびその応用
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WO2019241376A1 (en) 2018-06-14 2019-12-19 The Trustees Of Columbia University In The City Of New York Treatment of cognitive disorders using nitazoxanide (ntz), nitazoxanide (ntz) analogs, and metabolites thereof
CN110025621A (zh) * 2019-03-13 2019-07-19 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 替唑尼特和硝唑尼特在制备抗炎药物中的应用
CN111012788B (zh) * 2019-12-12 2021-01-15 武汉职业技术学院 硝唑尼特和替唑尼特在制备抗猪繁殖与呼吸综合征病毒药物中的应用
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JP2023537237A (ja) 2020-07-20 2023-08-31 ロマーク ラボラトリーズ,リミティド カンパニー チゾキサニドおよび2-ヒドロキシ-n-(5-クロロ-1,3-チアゾル-2-イル)ベンズアミド(rm-4848)とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびn-メチルピペラジンの結晶塩
IL300801A (en) 2020-08-24 2023-04-01 Romark Laboratories Lc Use of thiazolides against the corona virus
WO2022130406A1 (en) * 2020-12-15 2022-06-23 Cipla Limited Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease
US20240417381A1 (en) 2021-10-05 2024-12-19 Council Of Scientific And Industrial Research An Indian Registered Body Incorporated An improved process for the preparation of nitazoxanide and intermediates thereof
CN114259492A (zh) * 2021-12-21 2022-04-01 中以海德人工智能药物研发股份有限公司 硝唑尼特在治疗乙肝中的应用

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Also Published As

Publication number Publication date
US20160243087A1 (en) 2016-08-25
JP6117845B2 (ja) 2017-04-19
KR101697800B1 (ko) 2017-01-18
CA2752233C (en) 2017-01-03
EA201190127A1 (ru) 2012-03-30
EP2395840B1 (en) 2020-04-15
BRPI1007945B1 (pt) 2020-08-04
MX348282B (es) 2017-06-05
US20190321338A1 (en) 2019-10-24
AU2017203148A1 (en) 2017-06-01
IL214624A0 (en) 2011-09-27
BRPI1007945A2 (pt) 2015-09-01
BRPI1007945C1 (pt) 2020-09-01
CA2752233A1 (en) 2010-08-19
SI2395840T1 (sl) 2020-08-31
US11426388B2 (en) 2022-08-30
US20100209505A1 (en) 2010-08-19
PL2395840T3 (pl) 2020-09-07
BRPI1007945C8 (pt) 2021-05-25
CO6501159A2 (es) 2012-08-15
EA029018B1 (ru) 2018-01-31
JP5726766B2 (ja) 2015-06-03
EP2395840A4 (en) 2013-12-25
JP6491174B2 (ja) 2019-03-27
CN107260695A (zh) 2017-10-20
US20180085353A1 (en) 2018-03-29
JP2012518002A (ja) 2012-08-09
JP2015143258A (ja) 2015-08-06
US9827227B2 (en) 2017-11-28
LT2395840T (lt) 2020-07-10
DK2395840T3 (da) 2020-06-08
EP2395840A1 (en) 2011-12-21
CY1123162T1 (el) 2021-10-29
AU2010213678B2 (en) 2015-11-26
MX2011008530A (es) 2011-10-14
US20140065215A1 (en) 2014-03-06
WO2010093854A1 (en) 2010-08-19
UA107564C2 (uk) 2015-01-26
ES2797493T3 (es) 2020-12-02
PT2395840T (pt) 2020-07-06
BRPI1007945B8 (pt) 2020-08-18
HRP20201055T1 (hr) 2020-10-30
MX381895B (es) 2025-03-13
CN102395276A (zh) 2012-03-28
US10383855B2 (en) 2019-08-20
AU2016200971A1 (en) 2016-03-03
JP2017061561A (ja) 2017-03-30
KR20120008024A (ko) 2012-01-25
US8524278B2 (en) 2013-09-03
AU2017203148B2 (en) 2018-08-09
US9351937B2 (en) 2016-05-31
AU2016200971B2 (en) 2017-02-23
AU2010213678A1 (en) 2011-09-01

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