HUE049003T2 - Eljárás mikrovezikulumok izolálására és tisztítására sejttenyészet-felülúszóból és biológiai folyadékból - Google Patents
Eljárás mikrovezikulumok izolálására és tisztítására sejttenyészet-felülúszóból és biológiai folyadékbólInfo
- Publication number
- HUE049003T2 HUE049003T2 HUE14774189A HUE14774189A HUE049003T2 HU E049003 T2 HUE049003 T2 HU E049003T2 HU E14774189 A HUE14774189 A HU E14774189A HU E14774189 A HUE14774189 A HU E14774189A HU E049003 T2 HUE049003 T2 HU E049003T2
- Authority
- HU
- Hungary
- Prior art keywords
- microvesicles
- isolation
- purification
- cell culture
- culture supernatants
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/983—Blood, e.g. plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/86—Products or compounds obtained by genetic engineering
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361778591P | 2013-03-13 | 2013-03-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE049003T2 true HUE049003T2 (hu) | 2020-09-28 |
Family
ID=51625222
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE19212541A HUE062348T2 (hu) | 2013-03-13 | 2014-03-12 | Eljárás mikrovezikulumok sejttenyészet felülúszójából és biológiai folyadékokból történõ izolálására és tisztítására |
HUE14774189A HUE049003T2 (hu) | 2013-03-13 | 2014-03-12 | Eljárás mikrovezikulumok izolálására és tisztítására sejttenyészet-felülúszóból és biológiai folyadékból |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE19212541A HUE062348T2 (hu) | 2013-03-13 | 2014-03-12 | Eljárás mikrovezikulumok sejttenyészet felülúszójából és biológiai folyadékokból történõ izolálására és tisztítására |
Country Status (13)
Country | Link |
---|---|
US (3) | US10500231B2 (hu) |
EP (3) | EP3677271B1 (hu) |
JP (3) | JP6562897B2 (hu) |
CN (2) | CN112795533A (hu) |
AU (4) | AU2014244618A1 (hu) |
CA (1) | CA2906502A1 (hu) |
DK (2) | DK3677271T3 (hu) |
ES (2) | ES2778098T3 (hu) |
FI (1) | FI3677271T3 (hu) |
HU (2) | HUE062348T2 (hu) |
PL (2) | PL3677271T3 (hu) |
PT (2) | PT2972193T (hu) |
WO (1) | WO2014159662A1 (hu) |
Families Citing this family (30)
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US10640464B2 (en) | 2011-01-03 | 2020-05-05 | The William M. Yarbrough Foundation | Use of isothiocyanate functional surfactants as Nrf2 inducers to treat epidermolysis bullosa simplex and related diseases |
JP6562897B2 (ja) * | 2013-03-13 | 2019-08-21 | ユニバーシティー オブ マイアミUniversity Of Miami | 細胞培養上清および生体液からの微小胞の単離および精製のための方法 |
US11160904B2 (en) | 2017-05-09 | 2021-11-02 | Vivex Biologies Group, Inc. | Biological composition in a protectant shroud and methods |
US9687511B2 (en) * | 2015-03-06 | 2017-06-27 | Vivex Biomedical, Inc. | Acellular biologic composition and method of manufacture |
EP3267965A4 (en) * | 2015-03-11 | 2018-11-14 | Atta Behfar | Exosome delivery technology |
WO2016149358A1 (en) * | 2015-03-16 | 2016-09-22 | Duncan Ross | Method of treatment comprising membrane-enclosed vesicle |
RS64469B1 (sr) * | 2015-07-31 | 2023-09-29 | Exotropin Llc | Kompozicije egzozoma i postupci za njihovu pripremu i primenu za regulisanje i kondicioniranje kože i kose |
KR102418785B1 (ko) * | 2015-09-25 | 2022-07-08 | (주)프로스테믹스 | 식물 착즙물 유래 세포 외 소포체를 포함하는 피부 개선 및 탈모 방지용 조성물 |
KR102475127B1 (ko) * | 2015-09-30 | 2022-12-07 | (주)아모레퍼시픽 | 인삼 유래의 엑소좀 유사 베지클을 포함하는 탈모 방지 또는 육모 촉진용 조성물 |
JP2019501179A (ja) * | 2015-12-30 | 2019-01-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 細胞由来ベシクルの向上された生成および単離のための方法 |
JP2019505590A (ja) * | 2016-01-19 | 2019-02-28 | ジェイ. サイレン、マッティ | 癌の予防、処置および/または緩和における使用のための方法および組成物 |
KR102475129B1 (ko) * | 2016-03-22 | 2022-12-07 | (주)아모레퍼시픽 | 인삼 유래의 엑소좀 유사 베지클을 유효성분으로 포함하는 항노화용 조성물 |
WO2018039100A2 (en) * | 2016-08-23 | 2018-03-01 | Albert Einstein College Of Medicine, Inc. | Stem cell-produced microvesicles for treating tendon pathologies |
EP4364799A2 (en) * | 2017-01-11 | 2024-05-08 | Paracelsus Medizinische Privatuniversität Salzburg - Privatstiftung | Mesenchymal stem cell-derived extracellular vesicles and their medical use |
US11904259B2 (en) | 2017-07-26 | 2024-02-20 | Rosetta Exosome | Method for isolating extracellular vesicles using cations |
US20200264076A1 (en) * | 2017-07-27 | 2020-08-20 | Cornell University | Fixation and retention of extracellular vesicles |
KR20200088799A (ko) * | 2017-09-22 | 2020-07-23 | 더 유니버시티 오브 마이애미 | 수포성 표피박리증의 치료를 위한 방법 및 조성물 |
US11471559B2 (en) * | 2017-11-20 | 2022-10-18 | Vivex Biologics Group, Inc. | Bioenergetic bone |
AU2019212824B2 (en) * | 2018-01-29 | 2023-02-02 | Forever Labs, Inc. | System and method for isolating extracellular vesicles |
CN108414334A (zh) * | 2018-02-23 | 2018-08-17 | 中山大学附属第医院 | 一种从精液中分离提纯外泌体的方法 |
EP3852608A4 (en) | 2018-09-21 | 2022-09-28 | Aufbau Medical Innovations Limited | COMPOSITIONS AND METHODS FOR TREATING GLAUCOMA |
EP3930734A4 (en) * | 2019-02-28 | 2022-12-07 | Merakris Therapeutics, LLC | EXTRACELLULAR VESICLES DERIVED FROM AMNIOTIC FLUID AND THEIR USES FOR WOUND HEALING |
CN113384597A (zh) * | 2020-03-13 | 2021-09-14 | 西比曼生物科技(上海)有限公司 | 含人体细胞衍生的细胞膜外囊泡的雾化吸入制剂、制法及其应用 |
CN111893093A (zh) * | 2020-08-03 | 2020-11-06 | 沈阳三禾生物科技有限公司 | 一种脐带间充质干细胞来源的超微因子的制备方法 |
AU2021327376A1 (en) | 2020-08-21 | 2023-04-20 | University Of Miami | Compositions and methods of treatment using microvesicles from bone marrow-derived mesenchymal stem cells |
WO2022080461A1 (ja) * | 2020-10-16 | 2022-04-21 | 富士フイルム和光純薬株式会社 | 細胞外小胞の産生用培地、培地キット、添加剤及び細胞外小胞の産生方法 |
CN114081900A (zh) * | 2021-02-24 | 2022-02-25 | 济宁医学院附属医院 | 间充质干细胞来源的纳米微囊泡在制备治疗子痫前期的药物中的应用 |
CN115212230A (zh) * | 2021-04-21 | 2022-10-21 | 西比曼生物科技(上海)有限公司 | 含有干细胞胞外囊泡的药物组合物及其在呼吸道炎症治疗中的应用 |
WO2023205158A1 (en) | 2022-04-19 | 2023-10-26 | University Of Miami | Compositions comprising microvesicles for use in the prevention and treatment of graft versus host disease |
KR20240028586A (ko) * | 2022-08-24 | 2024-03-05 | (주) 테라베스트 | 인간 세포 유래 미세소포체 및 히알루론산 또는 콜라겐을 포함하는 조성물 및 이의 용도 |
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