HUE047238T2 - Szérumalbuminhoz kötõdõ fehérjék - Google Patents
Szérumalbuminhoz kötõdõ fehérjékInfo
- Publication number
- HUE047238T2 HUE047238T2 HUE12727658A HUE12727658A HUE047238T2 HU E047238 T2 HUE047238 T2 HU E047238T2 HU E12727658 A HUE12727658 A HU E12727658A HU E12727658 A HUE12727658 A HU E12727658A HU E047238 T2 HUE047238 T2 HU E047238T2
- Authority
- HU
- Hungary
- Prior art keywords
- serum albumin
- binding proteins
- albumin binding
- proteins
- serum
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161500464P | 2011-06-23 | 2011-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE047238T2 true HUE047238T2 (hu) | 2020-04-28 |
Family
ID=46298413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE12727658A HUE047238T2 (hu) | 2011-06-23 | 2012-06-14 | Szérumalbuminhoz kötõdõ fehérjék |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9573992B2 (OSRAM) |
| EP (3) | EP3466972A1 (OSRAM) |
| JP (3) | JP6324887B2 (OSRAM) |
| CN (2) | CN106046168A (OSRAM) |
| AU (1) | AU2012271974B2 (OSRAM) |
| CA (1) | CA2839779C (OSRAM) |
| CY (1) | CY1122691T1 (OSRAM) |
| DK (1) | DK2723771T3 (OSRAM) |
| ES (1) | ES2759936T3 (OSRAM) |
| HR (2) | HRP20192160T1 (OSRAM) |
| HU (1) | HUE047238T2 (OSRAM) |
| IN (1) | IN2014CN00414A (OSRAM) |
| LT (1) | LT2723771T (OSRAM) |
| PL (1) | PL2723771T3 (OSRAM) |
| PT (1) | PT2723771T (OSRAM) |
| SI (1) | SI2723771T1 (OSRAM) |
| WO (1) | WO2012175400A1 (OSRAM) |
Families Citing this family (87)
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| EP2621953B1 (en) | 2010-09-30 | 2017-04-05 | Ablynx N.V. | Biological materials related to c-met |
| US11644471B2 (en) | 2010-09-30 | 2023-05-09 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| LT2723771T (lt) * | 2011-06-23 | 2019-12-10 | Ablynx Nv | Serumo albuminą surišantys baltymai |
| CN108653728B (zh) | 2011-06-23 | 2022-11-18 | 埃博灵克斯股份有限公司 | 用于预测、检测和减少涉及免疫球蛋白单可变结构域的测定法中的非特异性蛋白干扰的技术 |
| US9346884B2 (en) | 2011-09-30 | 2016-05-24 | Ablynx N.V. | Biological materials related to c-Met |
| CN103889451B (zh) * | 2011-09-30 | 2016-06-29 | 埃博灵克斯股份有限公司 | 与C-Met相关的生物物质 |
| WO2014087010A1 (en) | 2012-12-07 | 2014-06-12 | Ablynx N.V. | IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE |
| CA2948945C (en) | 2014-05-16 | 2023-08-08 | Ablynx Nv | Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies |
| EP3702369A1 (en) | 2014-05-16 | 2020-09-02 | Ablynx NV | Immunoglobulin variable domains |
| NL2013661B1 (en) | 2014-10-21 | 2016-10-05 | Ablynx Nv | KV1.3 Binding immunoglobulins. |
| ES2772348T3 (es) | 2014-12-19 | 2020-07-07 | Ablynx Nv | Dímeros de Nanobody con uniones cisteína |
| AU2016210835B2 (en) | 2015-01-29 | 2021-01-21 | Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa | Antibody molecules and peptide delivery systems for use in alzheimer's disease and related disorders |
| KR101997241B1 (ko) | 2015-05-21 | 2019-07-09 | 하푼 테라퓨틱스, 인크. | 삼중특이성 결합 단백질 및 사용 방법 |
| NO2768984T3 (OSRAM) | 2015-11-12 | 2018-06-09 | ||
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| MA43259A (fr) | 2015-11-18 | 2018-09-26 | Merck Sharp & Dohme | Liants ctla4 |
| WO2017085172A2 (en) * | 2015-11-18 | 2017-05-26 | Ablynx Nv | Improved serum albumin binders |
| IL300122A (en) | 2015-11-18 | 2023-03-01 | Merck Sharp ַ& Dohme Llc | Substances that bind to PD1 and/or LAG3 |
| CN109071639B (zh) | 2015-11-18 | 2022-07-08 | 默沙东公司 | Pd1/ctla4结合剂 |
| CA3006398A1 (en) * | 2015-11-27 | 2017-06-01 | Ablynx Nv | Polypeptides inhibiting cd40l |
| CN119060177A (zh) * | 2016-05-20 | 2024-12-03 | 哈普恩治疗公司 | 单结构域血清白蛋白结合蛋白质 |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| PL3475699T3 (pl) | 2016-06-23 | 2022-09-26 | Ablynx N.V. | Ulepszone oznaczenia farmakokinetyczne dla pojedynczych domen zmiennych immunoglobuliny |
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| KR20230061582A (ko) * | 2016-12-07 | 2023-05-08 | 아블린쓰 엔.브이. | 개선된 혈청 알부민 결합성 면역글로불린 단일 가변 도메인 |
| CN107674122A (zh) * | 2016-12-28 | 2018-02-09 | 天津天锐生物科技有限公司 | 一种识别人血清白蛋白的单域抗体 |
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-
2012
- 2012-06-14 LT LT12727658T patent/LT2723771T/lt unknown
- 2012-06-14 EP EP18205150.8A patent/EP3466972A1/en active Pending
- 2012-06-14 DK DK12727658T patent/DK2723771T3/da active
- 2012-06-14 US US14/128,719 patent/US9573992B2/en active Active
- 2012-06-14 HU HUE12727658A patent/HUE047238T2/hu unknown
- 2012-06-14 PT PT127276582T patent/PT2723771T/pt unknown
- 2012-06-14 CA CA2839779A patent/CA2839779C/en active Active
- 2012-06-14 AU AU2012271974A patent/AU2012271974B2/en active Active
- 2012-06-14 ES ES12727658T patent/ES2759936T3/es active Active
- 2012-06-14 WO PCT/EP2012/061304 patent/WO2012175400A1/en not_active Ceased
- 2012-06-14 SI SI201231696T patent/SI2723771T1/sl unknown
- 2012-06-14 PL PL12727658T patent/PL2723771T3/pl unknown
- 2012-06-14 HR HRP20192160TT patent/HRP20192160T1/hr unknown
- 2012-06-14 JP JP2014516279A patent/JP6324887B2/ja active Active
- 2012-06-14 EP EP12727658.2A patent/EP2723771B1/en active Active
- 2012-06-14 CN CN201610392570.9A patent/CN106046168A/zh active Pending
- 2012-06-14 IN IN414CHN2014 patent/IN2014CN00414A/en unknown
- 2012-06-14 CN CN201280030647.8A patent/CN103619878B/zh active Active
- 2012-06-14 EP EP23159592.7A patent/EP4218933A1/en active Pending
- 2012-06-25 HR HRP20170535TT patent/HRP20170535T4/hr unknown
-
2017
- 2017-01-03 US US15/397,313 patent/US20170210789A1/en not_active Abandoned
-
2018
- 2018-04-11 JP JP2018076201A patent/JP6843090B2/ja active Active
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2019
- 2019-12-10 CY CY20191101299T patent/CY1122691T1/el unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| LT2723771T (lt) | 2019-12-10 |
| CA2839779A1 (en) | 2012-12-27 |
| JP2021088585A (ja) | 2021-06-10 |
| EP4218933A1 (en) | 2023-08-02 |
| JP6324887B2 (ja) | 2018-05-16 |
| CN103619878B (zh) | 2016-10-26 |
| HRP20192160T1 (hr) | 2020-02-21 |
| PT2723771T (pt) | 2019-12-11 |
| CN106046168A (zh) | 2016-10-26 |
| US20140228546A1 (en) | 2014-08-14 |
| HRP20170535T1 (hr) | 2017-06-16 |
| WO2012175400A1 (en) | 2012-12-27 |
| CY1122691T1 (el) | 2021-03-12 |
| PL2723771T3 (pl) | 2020-04-30 |
| CN103619878A (zh) | 2014-03-05 |
| DK2723771T3 (da) | 2019-12-02 |
| SI2723771T1 (sl) | 2019-12-31 |
| AU2012271974B2 (en) | 2017-01-12 |
| EP2723771A1 (en) | 2014-04-30 |
| EP2723771B1 (en) | 2019-09-11 |
| EP3466972A1 (en) | 2019-04-10 |
| IN2014CN00414A (OSRAM) | 2015-04-03 |
| JP6843090B2 (ja) | 2021-03-17 |
| US9573992B2 (en) | 2017-02-21 |
| US20170210789A1 (en) | 2017-07-27 |
| JP2018127478A (ja) | 2018-08-16 |
| JP7304375B2 (ja) | 2023-07-06 |
| ES2759936T3 (es) | 2020-05-12 |
| JP2014520129A (ja) | 2014-08-21 |
| HRP20170535T4 (hr) | 2022-08-19 |
| AU2012271974A1 (en) | 2013-12-12 |
| CA2839779C (en) | 2020-10-06 |
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