HUE047238T2 - Szérumalbuminhoz kötõdõ fehérjék - Google Patents
Szérumalbuminhoz kötõdõ fehérjékInfo
- Publication number
- HUE047238T2 HUE047238T2 HUE12727658A HUE12727658A HUE047238T2 HU E047238 T2 HUE047238 T2 HU E047238T2 HU E12727658 A HUE12727658 A HU E12727658A HU E12727658 A HUE12727658 A HU E12727658A HU E047238 T2 HUE047238 T2 HU E047238T2
- Authority
- HU
- Hungary
- Prior art keywords
- serum albumin
- binding proteins
- albumin binding
- proteins
- serum
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161500464P | 2011-06-23 | 2011-06-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE047238T2 true HUE047238T2 (hu) | 2020-04-28 |
Family
ID=46298413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE12727658A HUE047238T2 (hu) | 2011-06-23 | 2012-06-14 | Szérumalbuminhoz kötõdõ fehérjék |
Country Status (17)
Country | Link |
---|---|
US (2) | US9573992B2 (hu) |
EP (3) | EP2723771B1 (hu) |
JP (3) | JP6324887B2 (hu) |
CN (2) | CN103619878B (hu) |
AU (1) | AU2012271974B2 (hu) |
CA (1) | CA2839779C (hu) |
CY (1) | CY1122691T1 (hu) |
DK (1) | DK2723771T3 (hu) |
ES (1) | ES2759936T3 (hu) |
HR (2) | HRP20170535T4 (hu) |
HU (1) | HUE047238T2 (hu) |
IN (1) | IN2014CN00414A (hu) |
LT (1) | LT2723771T (hu) |
PL (1) | PL2723771T3 (hu) |
PT (1) | PT2723771T (hu) |
SI (1) | SI2723771T1 (hu) |
WO (1) | WO2012175400A1 (hu) |
Families Citing this family (59)
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US11644471B2 (en) | 2010-09-30 | 2023-05-09 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
EP2621953B1 (en) | 2010-09-30 | 2017-04-05 | Ablynx N.V. | Biological materials related to c-met |
KR102240318B1 (ko) * | 2011-06-23 | 2021-04-15 | 아블린쓰 엔.브이. | 면역글로불린 단일 가변 도메인을 수반하는 어세이에서 비특이적 단백질 간섭을 예측하고 검출하고 감소시키는 기법 |
JP6324887B2 (ja) * | 2011-06-23 | 2018-05-16 | アブリンクス エン.ヴェー. | 血清アルブミンに結合するタンパク質 |
CN103889451B (zh) * | 2011-09-30 | 2016-06-29 | 埃博灵克斯股份有限公司 | 与C-Met相关的生物物质 |
US9346884B2 (en) | 2011-09-30 | 2016-05-24 | Ablynx N.V. | Biological materials related to c-Met |
WO2014087010A1 (en) | 2012-12-07 | 2014-06-12 | Ablynx N.V. | IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE |
AU2015261467B2 (en) | 2014-05-16 | 2020-12-17 | Ablynx Nv | Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies |
AU2015261536B2 (en) | 2014-05-16 | 2020-05-07 | Ablynx Nv | Improved immunoglobulin variable domains |
NL2013661B1 (en) | 2014-10-21 | 2016-10-05 | Ablynx Nv | KV1.3 Binding immunoglobulins. |
AU2015366284B2 (en) | 2014-12-19 | 2021-07-22 | Ablynx N.V. | Cysteine linked nanobody dimers |
JP6986967B2 (ja) | 2015-01-29 | 2021-12-22 | テクノファージ, インベスティガサン エ デセンボルビメント エム ビオテクノロジア,エスエー | アルツハイマー病及び関連障害に使用するための抗体分子及びペプチド送達システム |
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JP7046804B2 (ja) * | 2015-11-18 | 2022-04-04 | アブリンクス エン.ヴェー. | 改良された血清アルブミン結合剤 |
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WO2017087587A1 (en) | 2015-11-18 | 2017-05-26 | Merck Sharp & Dohme Corp. | PD1/CTLA4 Binders |
CN108473561B (zh) | 2015-11-27 | 2022-12-16 | 埃博灵克斯股份有限公司 | 抑制cd40l的多肽 |
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KR20230061582A (ko) * | 2016-12-07 | 2023-05-08 | 아블린쓰 엔.브이. | 개선된 혈청 알부민 결합성 면역글로불린 단일 가변 도메인 |
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CN111465612A (zh) | 2017-10-13 | 2020-07-28 | 哈普恩治疗公司 | B细胞成熟抗原结合蛋白 |
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CN110964107B (zh) * | 2018-09-30 | 2022-08-09 | 苏州康宁杰瑞生物科技有限公司 | Met结合分子、其组合和用途 |
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CN111138537B (zh) * | 2018-11-06 | 2021-07-09 | 瑞阳(苏州)生物科技有限公司 | 一种抗人血清白蛋白抗体片段、制备方法和应用 |
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CN114980974A (zh) | 2019-12-09 | 2022-08-30 | 艾伯霖克斯公司 | 含靶向il-13和tslp的免疫球蛋白单可变结构域的多肽 |
CN110988361B (zh) * | 2019-12-13 | 2020-09-18 | 山东民康生物科技有限公司 | 人血清白蛋白去除试剂盒 |
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CN112142846B (zh) * | 2020-10-10 | 2022-07-08 | 西北大学 | Aox特异性抗体组合及其制备方法和用途 |
WO2022089435A1 (en) * | 2020-10-27 | 2022-05-05 | Beijing Ql Biopharmaceutical Co., Ltd. | Fusion proteins of gdf15 and use thereof |
KR20230123497A (ko) | 2020-12-18 | 2023-08-23 | 아블린쓰 엔.브이. | IL-6 및 TNF-α를 표적화하는 면역글로불린 단일 가변도메인을 포함하는 폴리펩티드 |
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CN103003307B (zh) | 2010-03-10 | 2017-08-11 | 根马布股份公司 | 抗c‑MEt的单克隆抗体 |
US11644471B2 (en) | 2010-09-30 | 2023-05-09 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
EP2621953B1 (en) | 2010-09-30 | 2017-04-05 | Ablynx N.V. | Biological materials related to c-met |
JP6324887B2 (ja) * | 2011-06-23 | 2018-05-16 | アブリンクス エン.ヴェー. | 血清アルブミンに結合するタンパク質 |
KR102240318B1 (ko) | 2011-06-23 | 2021-04-15 | 아블린쓰 엔.브이. | 면역글로불린 단일 가변 도메인을 수반하는 어세이에서 비특이적 단백질 간섭을 예측하고 검출하고 감소시키는 기법 |
US20150344568A1 (en) | 2011-06-23 | 2015-12-03 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
EP2744822B1 (en) | 2011-08-17 | 2020-06-24 | Glaxo Group Limited | Modified proteins and peptides |
US9346884B2 (en) | 2011-09-30 | 2016-05-24 | Ablynx N.V. | Biological materials related to c-Met |
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2012
- 2012-06-14 JP JP2014516279A patent/JP6324887B2/ja active Active
- 2012-06-14 CA CA2839779A patent/CA2839779C/en active Active
- 2012-06-14 EP EP12727658.2A patent/EP2723771B1/en active Active
- 2012-06-14 PL PL12727658T patent/PL2723771T3/pl unknown
- 2012-06-14 CN CN201280030647.8A patent/CN103619878B/zh active Active
- 2012-06-14 EP EP18205150.8A patent/EP3466972A1/en active Pending
- 2012-06-14 DK DK12727658T patent/DK2723771T3/da active
- 2012-06-14 PT PT127276582T patent/PT2723771T/pt unknown
- 2012-06-14 AU AU2012271974A patent/AU2012271974B2/en active Active
- 2012-06-14 EP EP23159592.7A patent/EP4218933A1/en active Pending
- 2012-06-14 WO PCT/EP2012/061304 patent/WO2012175400A1/en active Application Filing
- 2012-06-14 ES ES12727658T patent/ES2759936T3/es active Active
- 2012-06-14 SI SI201231696T patent/SI2723771T1/sl unknown
- 2012-06-14 US US14/128,719 patent/US9573992B2/en active Active
- 2012-06-14 CN CN201610392570.9A patent/CN106046168A/zh active Pending
- 2012-06-14 HU HUE12727658A patent/HUE047238T2/hu unknown
- 2012-06-14 LT LT12727658T patent/LT2723771T/lt unknown
- 2012-06-14 IN IN414CHN2014 patent/IN2014CN00414A/en unknown
- 2012-06-25 HR HRP20170535TT patent/HRP20170535T4/hr unknown
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2017
- 2017-01-03 US US15/397,313 patent/US20170210789A1/en not_active Abandoned
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2018
- 2018-04-11 JP JP2018076201A patent/JP6843090B2/ja active Active
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2019
- 2019-11-29 HR HRP20192160TT patent/HRP20192160T1/hr unknown
- 2019-12-10 CY CY20191101299T patent/CY1122691T1/el unknown
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- 2021-02-22 JP JP2021026177A patent/JP7304375B2/ja active Active
Also Published As
Publication number | Publication date |
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JP6324887B2 (ja) | 2018-05-16 |
HRP20192160T1 (hr) | 2020-02-21 |
US20170210789A1 (en) | 2017-07-27 |
AU2012271974B2 (en) | 2017-01-12 |
IN2014CN00414A (hu) | 2015-04-03 |
DK2723771T3 (da) | 2019-12-02 |
EP2723771A1 (en) | 2014-04-30 |
SI2723771T1 (sl) | 2019-12-31 |
CY1122691T1 (el) | 2021-03-12 |
JP7304375B2 (ja) | 2023-07-06 |
PT2723771T (pt) | 2019-12-11 |
WO2012175400A1 (en) | 2012-12-27 |
AU2012271974A1 (en) | 2013-12-12 |
EP3466972A1 (en) | 2019-04-10 |
JP2014520129A (ja) | 2014-08-21 |
JP6843090B2 (ja) | 2021-03-17 |
PL2723771T3 (pl) | 2020-04-30 |
HRP20170535T4 (hr) | 2022-08-19 |
ES2759936T3 (es) | 2020-05-12 |
CN103619878A (zh) | 2014-03-05 |
CN103619878B (zh) | 2016-10-26 |
US9573992B2 (en) | 2017-02-21 |
CA2839779C (en) | 2020-10-06 |
CA2839779A1 (en) | 2012-12-27 |
LT2723771T (lt) | 2019-12-10 |
JP2018127478A (ja) | 2018-08-16 |
US20140228546A1 (en) | 2014-08-14 |
EP4218933A1 (en) | 2023-08-02 |
HRP20170535T1 (hr) | 2017-06-16 |
CN106046168A (zh) | 2016-10-26 |
EP2723771B1 (en) | 2019-09-11 |
JP2021088585A (ja) | 2021-06-10 |
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