HUE045191T2 - Host sejtek és eljárások izobutanol elõállítására - Google Patents
Host sejtek és eljárások izobutanol elõállításáraInfo
- Publication number
- HUE045191T2 HUE045191T2 HUE12760879A HUE12760879A HUE045191T2 HU E045191 T2 HUE045191 T2 HU E045191T2 HU E12760879 A HUE12760879 A HU E12760879A HU E12760879 A HUE12760879 A HU E12760879A HU E045191 T2 HUE045191 T2 HU E045191T2
- Authority
- HU
- Hungary
- Prior art keywords
- isobutanol
- production
- methods
- host cells
- host
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161467261P | 2011-03-24 | 2011-03-24 | |
US201161467249P | 2011-03-24 | 2011-03-24 | |
US201161467271P | 2011-03-24 | 2011-03-24 | |
US201161472497P | 2011-04-06 | 2011-04-06 | |
US201161472484P | 2011-04-06 | 2011-04-06 | |
US201161472474P | 2011-04-06 | 2011-04-06 | |
US201161472487P | 2011-04-06 | 2011-04-06 | |
US201161570513P | 2011-12-14 | 2011-12-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE045191T2 true HUE045191T2 (hu) | 2019-12-30 |
Family
ID=46880082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE12760879A HUE045191T2 (hu) | 2011-03-24 | 2012-03-23 | Host sejtek és eljárások izobutanol elõállítására |
Country Status (13)
Country | Link |
---|---|
US (4) | US9790521B2 (hu) |
EP (1) | EP2689014B1 (hu) |
JP (1) | JP6099623B2 (hu) |
KR (1) | KR20140092759A (hu) |
CN (1) | CN103827304B (hu) |
AR (1) | AR088778A1 (hu) |
AU (2) | AU2012230737B2 (hu) |
BR (1) | BR112013024328A2 (hu) |
CA (1) | CA2831130C (hu) |
HU (1) | HUE045191T2 (hu) |
MX (1) | MX347976B (hu) |
WO (1) | WO2012129555A2 (hu) |
ZA (1) | ZA201306708B (hu) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
WO2008130995A2 (en) | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
CN102186983A (zh) | 2008-09-29 | 2011-09-14 | 布特马斯先进生物燃料有限责任公司 | 酵母中提高的异源Fe-S酶活性 |
NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
GB2492267B (en) | 2010-02-12 | 2013-05-01 | Gevo Inc | Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals and amino acids |
MX357290B (es) | 2010-02-17 | 2018-07-04 | Butamax Tm Advanced Biofuels | Mejoramiento de la actividad de proteínas que requieren centros fe-s. |
US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
WO2012033832A2 (en) | 2010-09-07 | 2012-03-15 | Butamax(Tm) Advanced Biofuels Llc | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
EP2689014B1 (en) | 2011-03-24 | 2019-04-24 | Butamax (TM) Advanced Biofuels LLC | Host cells and methods for production of isobutanol |
US20120258873A1 (en) * | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
EP2737073B1 (en) * | 2011-07-28 | 2021-10-20 | Butamax Advanced Biofuels LLC | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
US9181566B2 (en) | 2011-12-30 | 2015-11-10 | Butamax Advanced Biofuels Llc | Genetic switches for butanol production |
KR20140146616A (ko) | 2012-03-23 | 2014-12-26 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 부타놀로겐용 배지의 아세테이트 보충물 |
WO2013176909A2 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
WO2014031831A1 (en) | 2012-08-22 | 2014-02-27 | Butamax Advanced Biofuels Llc | Production of fermentation products |
WO2014047421A1 (en) | 2012-09-21 | 2014-03-27 | Butamax(Tm) Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
AU2013323427A1 (en) | 2012-09-26 | 2015-03-05 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
AU2013323396B2 (en) * | 2012-09-28 | 2017-04-20 | Butamax Advanced Biofuels Llc | Production of fermentation products |
US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
WO2014081848A1 (en) | 2012-11-20 | 2014-05-30 | Butamax Advanced Biofuels Llc | Butanol purification |
WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
US20160002131A1 (en) | 2013-02-21 | 2016-01-07 | Butamax Advanced Biofuels Llc | Vapor recompression |
US9441250B2 (en) | 2013-03-14 | 2016-09-13 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
WO2014144210A2 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
CN105229156A (zh) | 2013-03-15 | 2016-01-06 | 布特马斯先进生物燃料有限责任公司 | 用于利用提取发酵生产丁醇的方法 |
WO2014151645A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Process for maximizing biomass growth and butanol yield by feedback control |
WO2014144643A1 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Method for producing butanol using extractive fermentation |
CN105073991B (zh) * | 2013-03-28 | 2019-04-05 | 株式会社钟化 | 改变型羰基还原酶及其基因 |
US9663759B2 (en) | 2013-07-03 | 2017-05-30 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
CN105722969A (zh) | 2013-10-28 | 2016-06-29 | 丹尼斯科美国公司 | 大规模基因工程化活性干酵母 |
EP3967747B1 (en) | 2013-12-03 | 2023-11-08 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis |
US10280438B2 (en) | 2014-08-11 | 2019-05-07 | Butamax Advanced Biofuels Llc | Method for the production of yeast |
KR101632642B1 (ko) | 2015-01-29 | 2016-06-22 | 씨제이제일제당 주식회사 | 신규한 프로모터 및 그의 용도 |
US20190276905A1 (en) * | 2016-11-09 | 2019-09-12 | Danisco Us Inc. | Yeast with improved alcohol production |
US10796788B2 (en) * | 2017-06-19 | 2020-10-06 | Academia Sinica | Structural determination of carbohydrates using special procedure and database of mass spectra |
CA3068611A1 (en) * | 2017-06-30 | 2019-01-03 | Dow Global Technologies Llc | Coating for aldehyde remediation and method of making |
TWI760548B (zh) * | 2018-08-16 | 2022-04-11 | 葡萄王生技股份有限公司 | 包含胚芽乳酸桿菌gkm3之組合物之延緩老化之用途 |
TWI718402B (zh) * | 2018-08-16 | 2021-02-11 | 葡萄王生技股份有限公司 | 副乾酪乳酸桿菌gks6之活性物質、含其之組合物及其促進長壽之用途 |
CN111378681B (zh) * | 2018-12-27 | 2023-01-17 | 中国医学科学院药物研究所 | 生产达玛烯二醇-ii糖苷的重组菌及其应用 |
CN111826405B (zh) * | 2019-04-16 | 2022-09-27 | 中国科学院大连化学物理研究所 | 一种生物催化还原丙酮酸产d-乳酸的方法 |
CN110982771B (zh) * | 2019-12-26 | 2021-05-28 | 江南大学 | 一种合成对羟基扁桃酸的方法 |
CN110904061B (zh) * | 2019-12-28 | 2021-05-18 | 南京朗恩生物科技有限公司 | 一种热稳定性增强的醇脱氢酶突变体及其应用 |
CN110951704B (zh) * | 2019-12-28 | 2021-07-27 | 南京朗恩生物科技有限公司 | 一种热稳定性增强的醇脱氢酶突变体及其序列 |
WO2021178805A1 (en) * | 2020-03-06 | 2021-09-10 | Gevo, Inc. | Novel nkr variants for increased production of isobutanol |
Family Cites Families (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4865973A (en) | 1985-09-13 | 1989-09-12 | Queen's University At Kingston | Process for extractive fermentation |
FR2696190B1 (fr) | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
US20070031950A1 (en) | 1998-09-11 | 2007-02-08 | Winkler Aaron A | Production of D-lactic acid with yeast |
AU4395200A (en) | 1999-04-13 | 2000-11-14 | Universiteit Van Amsterdam | Process for the production of yeast biomass comprising functionally deleted (hxk2) genes |
ATE335823T1 (de) | 1999-08-18 | 2006-09-15 | Du Pont | Verfahren zur biologischen herstellung von 1,3- propandiol |
EP1268774A2 (en) | 2000-03-21 | 2003-01-02 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
US6586229B1 (en) | 2000-06-01 | 2003-07-01 | North Carolina State University | Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium |
US6960465B1 (en) | 2001-06-27 | 2005-11-01 | Northwestern University | Increased cell resistance to toxic organic substances |
IL159368A0 (en) | 2001-07-02 | 2004-06-01 | Kaneka Corp | Method of modifying enzyme and oxidoreductase variant |
CN1780560B (zh) | 2003-03-10 | 2011-05-25 | 布罗因联合公司 | 利用生淀粉生产乙醇的方法 |
US7405068B2 (en) | 2003-05-02 | 2008-07-29 | Tate & Lyle Ingredients Americas, Inc. | Pyruvate producing yeast strain |
SE526429C2 (sv) | 2003-10-24 | 2005-09-13 | Swedish Biofuels Ab | Metod för att framställa syreinnehållande föreningar utgående från biomassa |
GB0329722D0 (en) | 2003-12-23 | 2004-01-28 | Delta Biotechnology Ltd | Modified plasmid and use thereof |
WO2006110900A2 (en) | 2005-04-12 | 2006-10-19 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain ethanol |
US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
EP1948814B1 (en) | 2005-10-26 | 2018-11-21 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of four carbon alcohols |
US8956850B2 (en) | 2008-06-05 | 2015-02-17 | Butamax Advanced Biofuels Llc | Enhanced pyruvate to acetolactate conversion in yeast |
US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US8962298B2 (en) | 2006-05-02 | 2015-02-24 | Butamax Advanced Biofuels Llc | Recombinant host cell comprising a diol dehydratase |
US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US7659104B2 (en) | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
US7541173B2 (en) | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
KR100882418B1 (ko) | 2007-01-15 | 2009-02-05 | 씨제이제일제당 (주) | 이노신을 생산하는 미생물 및 그를 이용한 이노신 제조방법 |
MY147186A (en) | 2007-02-09 | 2012-11-14 | Univ California | Biofuel production by recombinant microorganisms |
WO2008130995A2 (en) * | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
EP2060632A1 (en) | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
WO2009059253A2 (en) | 2007-10-31 | 2009-05-07 | Gevo, Inc. | Methods for the economical production of biofuel from biomass |
EP2087116B1 (en) | 2007-12-17 | 2011-01-12 | Suntory Holdings Limited | Mutant ilv5 gene and use thereof |
ES2575413T3 (es) | 2007-12-20 | 2016-06-28 | Butamax (Tm) Advanced Biofuels Llc | Cetol-ácido reductoisomerasa que utiliza NADH |
US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
US8372612B2 (en) | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
US8455239B2 (en) | 2007-12-23 | 2013-06-04 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
CA2710359C (en) | 2007-12-23 | 2018-02-20 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
MX2010007210A (es) | 2007-12-27 | 2010-10-08 | Gevo Inc | Recuperacion de alcoholes superiores a partir de soluciones acuosas diluidas. |
US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
WO2009143455A2 (en) | 2008-05-22 | 2009-11-26 | Microbia, Inc. | Engineering resistance to aliphatic alcohols |
BRPI0909965A2 (pt) | 2008-06-04 | 2015-08-04 | Butamax Advanced Biofuels Llc | Método para a recuperação de butanol a partir de um meio de fermentação e método para a produção de butanol |
EP2342330A1 (en) | 2008-09-29 | 2011-07-13 | Butamax Advanced Biofuels Llc | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
CN102186973B (zh) | 2008-09-29 | 2017-08-15 | 布特马斯先进生物燃料有限责任公司 | 细菌的[2Fe‑2S]二羟酸脱水酶的鉴定和用途 |
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BRPI0913547A2 (pt) | 2008-09-29 | 2020-08-18 | Butamax Advanced Biofuels Llc | célula bacteriana ácido-lática recombinante, método para a produção de 2-butanol e método para a produção de 2-butanona |
BRPI0914521A2 (pt) | 2008-10-27 | 2016-07-26 | Butamax Advanced Biofuels Llc | célula hospedeira microbiana recombinante, método de aumento da produção de isobutanol e método de produção de isobutanol |
BRPI0921734A2 (pt) * | 2008-10-31 | 2019-01-08 | California Inst Of Techn | micro-organismos criados geneticamente capazes de produzir compostos-alvo sob condições anaeróbicas |
US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
US8828694B2 (en) * | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
US8357519B2 (en) | 2008-11-19 | 2013-01-22 | The Ohio State University | Methods and processes for producing esters |
US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
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US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
US8968522B2 (en) * | 2009-07-15 | 2015-03-03 | Butamax Advanced Biofuels Llc | Recovery of butanol isomers from a mixture of butanol isomers, water, and an organic extractant |
JP5356140B2 (ja) | 2009-07-22 | 2013-12-04 | ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー | 超音波診断装置及びその制御プログラム |
WO2011019894A1 (en) | 2009-08-12 | 2011-02-17 | Gevo, Inc. | Cytosolic isobutanol pathway localization for the production of isobutanol |
US9169499B2 (en) | 2009-09-29 | 2015-10-27 | Butamax Advanced Biofuels Llc | Flux to acetolactate-derived products in lactic acid bacteria |
US9260708B2 (en) | 2009-09-29 | 2016-02-16 | Butamax Advanced Biofuels Llc | Yeast production host cells |
BR112012007168A2 (pt) | 2009-09-29 | 2019-09-24 | Butamax Advanced Biofuels Llc | "célula de levedura, célula microbiana que produz isobutanol, célula hospedeira microbiana, método para conversão de acetolacto em diidróxi-isovalerato, método para a produção de isobutanol e plasmídeo" |
US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
MY156003A (en) * | 2009-11-24 | 2015-12-31 | Gevo Inc | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids |
NZ600585A (en) | 2009-12-29 | 2014-07-25 | Butamax Tm Advanced Biofuels | Expression of hexose kinase in recombinant host cells |
NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
GB2492267B (en) | 2010-02-12 | 2013-05-01 | Gevo Inc | Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals and amino acids |
MX357290B (es) | 2010-02-17 | 2018-07-04 | Butamax Tm Advanced Biofuels | Mejoramiento de la actividad de proteínas que requieren centros fe-s. |
WO2011159894A1 (en) | 2010-06-17 | 2011-12-22 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
AU2011268169A1 (en) | 2010-06-18 | 2012-12-06 | Butamax(Tm) Advanced Biofuels Llc | Production of alcohol esters and in situ product removal during alcohol fermentation |
WO2012027642A1 (en) | 2010-08-27 | 2012-03-01 | Gevo, Inc. | Balanced four-step pathways to renewable butanols |
WO2012033832A2 (en) | 2010-09-07 | 2012-03-15 | Butamax(Tm) Advanced Biofuels Llc | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
EP2689014B1 (en) | 2011-03-24 | 2019-04-24 | Butamax (TM) Advanced Biofuels LLC | Host cells and methods for production of isobutanol |
US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
WO2012173659A2 (en) | 2011-06-17 | 2012-12-20 | Butamax (Tm) Advanced Biofuels Llc | Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation |
EP2737073B1 (en) | 2011-07-28 | 2021-10-20 | Butamax Advanced Biofuels LLC | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
US9181566B2 (en) | 2011-12-30 | 2015-11-10 | Butamax Advanced Biofuels Llc | Genetic switches for butanol production |
CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
KR20140146616A (ko) | 2012-03-23 | 2014-12-26 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 부타놀로겐용 배지의 아세테이트 보충물 |
WO2013176909A2 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
AU2013323427A1 (en) | 2012-09-26 | 2015-03-05 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
US9441250B2 (en) | 2013-03-14 | 2016-09-13 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
-
2012
- 2012-03-23 EP EP12760879.2A patent/EP2689014B1/en active Active
- 2012-03-23 MX MX2013010823A patent/MX347976B/es active IP Right Grant
- 2012-03-23 WO PCT/US2012/030479 patent/WO2012129555A2/en active Application Filing
- 2012-03-23 AU AU2012230737A patent/AU2012230737B2/en active Active
- 2012-03-23 CN CN201280024903.2A patent/CN103827304B/zh active Active
- 2012-03-23 US US13/428,585 patent/US9790521B2/en active Active
- 2012-03-23 KR KR1020137027906A patent/KR20140092759A/ko not_active Application Discontinuation
- 2012-03-23 HU HUE12760879A patent/HUE045191T2/hu unknown
- 2012-03-23 CA CA2831130A patent/CA2831130C/en active Active
- 2012-03-23 BR BR112013024328-7A patent/BR112013024328A2/pt not_active Application Discontinuation
- 2012-03-23 JP JP2014501294A patent/JP6099623B2/ja active Active
- 2012-03-26 AR ARP120101001A patent/AR088778A1/es unknown
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2013
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- 2013-03-15 US US13/840,676 patent/US9422582B2/en active Active
- 2013-09-06 ZA ZA2013/06708A patent/ZA201306708B/en unknown
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2017
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- 2017-04-03 US US15/477,980 patent/US20170275652A1/en not_active Abandoned
Also Published As
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CN103827304B (zh) | 2018-04-17 |
MX347976B (es) | 2017-05-22 |
WO2012129555A3 (en) | 2013-02-28 |
WO2012129555A2 (en) | 2012-09-27 |
US20140030782A1 (en) | 2014-01-30 |
US9422581B2 (en) | 2016-08-23 |
BR112013024328A2 (pt) | 2020-08-25 |
JP2014508541A (ja) | 2014-04-10 |
MX2013010823A (es) | 2014-02-03 |
US9422582B2 (en) | 2016-08-23 |
AU2017200439A1 (en) | 2017-02-16 |
US20140030783A1 (en) | 2014-01-30 |
US20170275652A1 (en) | 2017-09-28 |
AU2012230737A1 (en) | 2013-09-19 |
ZA201306708B (en) | 2015-01-28 |
CN103827304A (zh) | 2014-05-28 |
CA2831130C (en) | 2021-10-26 |
AR088778A1 (es) | 2014-07-10 |
EP2689014A4 (en) | 2014-11-05 |
US9790521B2 (en) | 2017-10-17 |
US20130071898A1 (en) | 2013-03-21 |
EP2689014B1 (en) | 2019-04-24 |
JP6099623B2 (ja) | 2017-03-22 |
KR20140092759A (ko) | 2014-07-24 |
CA2831130A1 (en) | 2012-09-27 |
EP2689014A2 (en) | 2014-01-29 |
AU2012230737B2 (en) | 2017-02-23 |
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