HUE031689T2 - Oncolytic adenoviral vectors and related procedures and applications - Google Patents
Oncolytic adenoviral vectors and related procedures and applications Download PDFInfo
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- HUE031689T2 HUE031689T2 HUE09796016A HUE09796016A HUE031689T2 HU E031689 T2 HUE031689 T2 HU E031689T2 HU E09796016 A HUE09796016 A HU E09796016A HU E09796016 A HUE09796016 A HU E09796016A HU E031689 T2 HUE031689 T2 HU E031689T2
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| WO2011070440A2 (en) | 2009-12-10 | 2011-06-16 | Ottawa Hospital Research Institute | Oncolytic rhabdovirus |
| BR112013006699A2 (pt) * | 2010-09-24 | 2016-06-14 | Oncos Therapeutics Oy | vetor adenoviral oncolítico que codifica anticorpos anti-ctl4-4 monoclonais, célula e composição farmacêutica compreendendo o mesmo, método de produção de anticorpo monoclonal humano específico para ctla-4 em uma célula e uso do referido vetor adenoviral |
| EP2619224A1 (en) * | 2010-09-24 | 2013-07-31 | Oncos Therapeutics Oy | Oncolytic adenoviral vectors and methods and uses related thereto |
| FI123955B (en) | 2011-11-25 | 2014-01-15 | Oncos Therapeutics Ltd | Oncolytic adenovirus |
| DK2806883T3 (da) | 2012-01-25 | 2019-07-22 | Dnatrix Inc | Biomarkører og kombinationsterapier under anvendelse af onkolytisk virus og immunomodulation |
| JP2016513115A (ja) | 2013-02-21 | 2016-05-12 | チルドレンズ ホスピタル オブ イースタン オンタリオ リサーチ インスティチュート インコーポレイテッド | ワクチン組成物 |
| SG11201507393TA (en) | 2013-03-14 | 2015-10-29 | Salk Inst For Biological Studi | Oncolytic adenovirus compositions |
| US12421502B2 (en) | 2013-04-18 | 2025-09-23 | Tilt Biotherapeutics Oy | Enhanced adoptive cell therapy |
| DK3461491T3 (da) | 2013-04-18 | 2025-02-03 | Tilt Biotherapeutics Oy | Forbedret adoptiv celleterapi |
| US10350275B2 (en) * | 2013-09-21 | 2019-07-16 | Advantagene, Inc. | Methods of cytotoxic gene therapy to treat tumors |
| PL3198009T3 (pl) | 2014-09-24 | 2022-01-24 | Salk Institute For Biological Studies | Onkolityczne wirusy nowotworowe i sposoby zastosowania |
| CN107849111B (zh) * | 2015-05-04 | 2022-02-22 | Vcn生物科学有限公司 | 在免疫显性腺病毒抗原表位中具有突变的溶瘤腺病毒及其在癌症治疗中的用途 |
| FI127460B (en) | 2016-01-15 | 2018-06-29 | Targovax Oy | Combining adenovirus and chemotherapeutic agents for treating cancer |
| JP7054527B2 (ja) | 2016-02-23 | 2022-04-14 | ソーク インスティテュート フォー バイオロジカル スタディーズ | アデノウイルスの複製動態を測定するための高スループットアッセイ |
| JP7015551B2 (ja) | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
| ES3041500T3 (en) | 2016-03-10 | 2025-11-12 | Cg Oncology Inc | Methods of treating solid tumors by combination therapy |
| LT3293201T (lt) | 2016-09-12 | 2021-03-25 | Targovax Oy | Adenoviruso ir kontrolinio taško inhibitoriaus derinys vėžio gydymui |
| US20190275092A1 (en) * | 2016-11-01 | 2019-09-12 | Dnatrix, Inc. | Combination therapy for treatment of brain cancers |
| WO2018111767A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| CN108261426B (zh) * | 2017-01-04 | 2019-04-05 | 杭州康万达医药科技有限公司 | 药物组合物及其在治疗肿瘤和/或癌症的药物中的应用 |
| AU2018206304A1 (en) * | 2017-01-06 | 2019-07-04 | Stabilitech Biopharma Ltd | Virus |
| EP4599893A3 (en) | 2017-04-14 | 2025-11-05 | CG Oncology, Inc. | Cg0070 for treating bcg resistant bladder carcinoma in situ |
| JP7260173B2 (ja) | 2017-04-21 | 2023-04-18 | ベイラー カレッジ オブ メディスン | 腫瘍溶解性ウイルス療法および免疫療法 |
| BR112019024656A2 (pt) | 2017-05-25 | 2020-06-09 | Univ Central Florida Res Found Inc | vírus oncolíticos para a sensibilização de células tumorais para morte por células exterminadoras naturais |
| WO2019093435A1 (ja) * | 2017-11-08 | 2019-05-16 | 国立大学法人 鹿児島大学 | 安全を確保しながら転移性がんまで効果的に治療可能な、搭載する免疫誘導遺伝子の最適発現レベルを与える発現制御システムを有する腫瘍溶解性ウイルス（腫瘍溶解性免疫治療） |
| GB201804473D0 (en) * | 2018-03-21 | 2018-05-02 | Valo Therapeutics Oy | Modified oncolytic adenoviruses |
| JP7430395B2 (ja) | 2018-04-09 | 2024-02-13 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 複製特質が増強された腫瘍溶解性アデノウイルス組成物 |
| EP3725323A1 (en) | 2019-04-17 | 2020-10-21 | Targovax Asa | Oncolytic adenoviral vector expressing a member of the b7 family of costimulatory ligands and ada |
| EP3725888A1 (en) * | 2019-04-17 | 2020-10-21 | Targovax Asa | Oncolytic adenoviral vector expressing peptidylarginine deiminase and tissue inhibitor of metalloproteinase |
| EP3725322A1 (en) | 2019-04-17 | 2020-10-21 | Targovax Asa | Oncolytic adenoviral vector expressing granzyme and perforin |
| KR102601875B1 (ko) * | 2020-03-25 | 2023-11-14 | (주)큐리진 | 면역 회피성 항종양 아데노바이러스 |
| CN111909962A (zh) * | 2020-07-23 | 2020-11-10 | 药鼎(北京)国际细胞医学技术有限公司 | 一种治疗肝癌的病毒构建体及其用途和构建方法 |
| CN118853767A (zh) * | 2024-08-22 | 2024-10-29 | 华中科技大学同济医学院附属同济医院 | 一种新型溶瘤腺病毒载体及其构建方法和应用 |
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| AU5464000A (en) * | 1999-06-01 | 2000-12-18 | University Of Washington | Recombinant adenoviral vectors for cell specific infection and genome integration and expressing chimeric fiber proteins |
| US20020045264A1 (en) * | 2000-03-14 | 2002-04-18 | During Matthew J. | Production of chimeric capsid vectors |
| WO2005030261A1 (en) * | 2003-08-28 | 2005-04-07 | Cell Genesys, Inc. | Oncolytic adenoviral vectors encoding gm-csf |
| ES2276623B1 (es) * | 2005-12-12 | 2008-06-01 | Proyecto De Biomedicina Cima, S.L | Nuevos adenovirus recombinantes de replicacion condicionada (crad). |
| US20070292396A1 (en) * | 2006-03-02 | 2007-12-20 | Juan Fueyo | Combination therapy with oncolytic adenovirus |
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| CA2748180A1 (en) | 2010-07-01 |
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| BRPI0924123B1 (pt) | 2020-10-20 |
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| CA2748180C (en) | 2017-06-20 |
| CY1120039T1 (el) | 2018-12-12 |
| RU2520823C2 (ru) | 2014-06-27 |
| CN102264760B (zh) | 2017-03-22 |
| DK2379586T3 (en) | 2017-02-06 |
| EP2379586A1 (en) | 2011-10-26 |
| HRP20170165T1 (hr) | 2017-04-07 |
| CN102264760A (zh) | 2011-11-30 |
| AU2009332883A1 (en) | 2011-07-07 |
| BRPI0924123B8 (pt) | 2021-05-25 |
| KR101761094B1 (ko) | 2017-08-04 |
| AU2009332883B2 (en) | 2015-05-21 |
| JP6280084B2 (ja) | 2018-02-14 |
| SI2379586T1 (sl) | 2017-02-28 |
| SG173432A1 (en) | 2011-09-29 |
| ZA201104224B (en) | 2012-09-26 |
| EP2379586B1 (en) | 2016-11-02 |
| JP2012513209A (ja) | 2012-06-14 |
| WO2010072900A1 (en) | 2010-07-01 |
| RU2011130511A (ru) | 2013-01-27 |
| PT2379586T (pt) | 2017-02-09 |
| PL2379586T3 (pl) | 2017-08-31 |
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