HUE028882T2 - (S) -2-Amino-3- {4- [4- (2,4-dioxothiazolidin-5-ylmethyl) -phenoxy] -phenyl} -propionic acid and its methyl ester salts as interleukin inhibitors overweight or diabetes treatment - Google Patents
(S) -2-Amino-3- {4- [4- (2,4-dioxothiazolidin-5-ylmethyl) -phenoxy] -phenyl} -propionic acid and its methyl ester salts as interleukin inhibitors overweight or diabetes treatment Download PDFInfo
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- HUE028882T2 HUE028882T2 HUE06735487A HUE06735487A HUE028882T2 HU E028882 T2 HUE028882 T2 HU E028882T2 HU E06735487 A HUE06735487 A HU E06735487A HU E06735487 A HUE06735487 A HU E06735487A HU E028882 T2 HUE028882 T2 HU E028882T2
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Classifications
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- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
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- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
Landscapes
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- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
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| IN347DE2005 | 2005-02-17 | ||
| US11/096,718 US7521465B2 (en) | 2003-01-17 | 2005-03-31 | Diphenyl ether derivatives |
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| HUE028882T2 true HUE028882T2 (en) | 2017-01-30 |
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Country Status (9)
| Country | Link |
|---|---|
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| EP (1) | EP1848700B1 (enExample) |
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| HU (1) | HUE028882T2 (enExample) |
| PL (1) | PL1848700T3 (enExample) |
| WO (1) | WO2006089225A1 (enExample) |
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| US9969977B2 (en) * | 2002-09-20 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| US7781464B2 (en) * | 2003-01-17 | 2010-08-24 | Bexel Pharmaceuticals, Inc. | Heterocyclic diphenyl ethers |
| US7521465B2 (en) | 2003-01-17 | 2009-04-21 | Bexel Pharmaceuticals, Inc. | Diphenyl ether derivatives |
| US7087576B2 (en) * | 2003-10-07 | 2006-08-08 | Bexel Pharmaceuticals, Inc. | Dipeptide phenyl ethers |
| KR100814109B1 (ko) | 2006-01-09 | 2008-03-14 | 한국생명공학연구원 | 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물 |
| WO2008019306A2 (en) * | 2006-08-04 | 2008-02-14 | Decode Genetics Ehf | Aryl amino acid derivatives as inhibitors of lta4h (leukotriene a4 hydrolase) for treating inflammation |
| US20090069313A1 (en) * | 2007-09-06 | 2009-03-12 | Orchid Research Laboratories Ltd. | Novel MAO-A inhibitors |
| EP2300446B1 (en) * | 2008-05-20 | 2011-12-07 | Merck Sharp & Dohme Corp. | Efficient production of heterologous proteins using mannosyl transferase inhibitors |
| CN103108634B (zh) * | 2010-07-28 | 2015-08-12 | 幽兰化学医药有限公司 | 用于治疗肝病、肺病、糖尿病并发症和心血管疾病的二苯醚化合物 |
| WO2012153775A1 (ja) | 2011-05-10 | 2012-11-15 | 国立大学法人神戸大学 | Ras機能阻害作用を有するチオキソチアゾリジン誘導体 |
| EP3221299A1 (en) * | 2014-11-21 | 2017-09-27 | BSIM2 Biomolecular Simulations Lda. | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof |
| TW202019923A (zh) * | 2018-07-16 | 2020-06-01 | 義大利商吉斯藥品公司 | 作為Ｒｈｏ－激酶抑制劑之酪胺酸醯胺衍生物 |
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| JPH0228168A (ja) * | 1988-04-14 | 1990-01-30 | Sankyo Co Ltd | チアゾール誘導体 |
| US20020049240A1 (en) | 1994-12-19 | 2002-04-25 | Beecham Group P.1.C. | Novel compounds |
| US5166137A (en) | 1991-03-27 | 1992-11-24 | Nobipols Forskningsstiftelse | Guluronic acid polymers and use of same for inhibition of cytokine production |
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-
2005
- 2005-03-31 US US11/096,718 patent/US7521465B2/en not_active Expired - Fee Related
-
2006
- 2006-02-17 PL PL06735487T patent/PL1848700T3/pl unknown
- 2006-02-17 ES ES06735487.8T patent/ES2566337T3/es not_active Expired - Lifetime
- 2006-02-17 CA CA2598087A patent/CA2598087C/en not_active Expired - Fee Related
- 2006-02-17 HU HUE06735487A patent/HUE028882T2/en unknown
- 2006-02-17 EP EP06735487.8A patent/EP1848700B1/en not_active Expired - Lifetime
- 2006-02-17 WO PCT/US2006/005846 patent/WO2006089225A1/en not_active Ceased
- 2006-02-17 KR KR1020077021343A patent/KR20070105364A/ko not_active Ceased
- 2006-02-17 JP JP2007556366A patent/JP5134974B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070105364A (ko) | 2007-10-30 |
| ES2566337T3 (es) | 2016-04-12 |
| EP1848700B1 (en) | 2015-12-30 |
| WO2006089225A1 (en) | 2006-08-24 |
| CA2598087C (en) | 2014-05-27 |
| US7521465B2 (en) | 2009-04-21 |
| PL1848700T3 (pl) | 2016-08-31 |
| JP5134974B2 (ja) | 2013-01-30 |
| JP2008530242A (ja) | 2008-08-07 |
| CA2598087A1 (en) | 2006-08-24 |
| EP1848700A1 (en) | 2007-10-31 |
| US20050288341A1 (en) | 2005-12-29 |
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