HU9903007D0 - Process for acylation of epsilon-amino groups thereof insulin - Google Patents

Process for acylation of epsilon-amino groups thereof insulin

Info

Publication number
HU9903007D0
HU9903007D0 HU9903007A HU9903007A HU9903007D0 HU 9903007 D0 HU9903007 D0 HU 9903007D0 HU 9903007 A HU9903007 A HU 9903007A HU 9903007 A HU9903007 A HU 9903007A HU 9903007 D0 HU9903007 D0 HU 9903007D0
Authority
HU
Hungary
Prior art keywords
epsilon
acylation
insulin
amino groups
amino
Prior art date
Application number
HU9903007A
Other languages
English (en)
Hungarian (hu)
Inventor
Jeffrey Clayton Baker
Victor John Chen
Jose Michael Hanquier
Aidas Vladas Kriauciunas
Brian Allen Moser
Robert Theodore Shuman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU9903007D0 publication Critical patent/HU9903007D0/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU9903007A 1994-11-17 1995-11-14 Process for acylation of epsilon-amino groups thereof insulin HU9903007D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/341,231 US5646242A (en) 1994-11-17 1994-11-17 Selective acylation of epsilon-amino groups
HU9800566A HU217585B (hu) 1994-11-17 1995-11-14 Eljárás inzulin epszilon-aminocsoportjainak szelektív acilezésére

Publications (1)

Publication Number Publication Date
HU9903007D0 true HU9903007D0 (en) 1999-11-29

Family

ID=23336740

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9800566A HU217585B (hu) 1994-11-17 1995-11-14 Eljárás inzulin epszilon-aminocsoportjainak szelektív acilezésére
HU9903007A HU9903007D0 (en) 1994-11-17 1995-11-14 Process for acylation of epsilon-amino groups thereof insulin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU9800566A HU217585B (hu) 1994-11-17 1995-11-14 Eljárás inzulin epszilon-aminocsoportjainak szelektív acilezésére

Country Status (27)

Country Link
US (2) US5646242A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP1227107A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP4312828B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1171742A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR003915A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE328902T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU691066B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9509652A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2205061A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CO (1) CO4520285A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ287731B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69535031T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0712862T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2264124T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (2) HU217585B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL115972A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN179820B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO972185D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ297256A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL320556A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT712862E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2155773C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI0712862T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR199501421A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1996015803A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU71495A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA959680B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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US6828305B2 (en) * 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
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US7166571B2 (en) * 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
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US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
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Also Published As

Publication number Publication date
PT712862E (pt) 2006-08-31
AR003915A1 (es) 1998-09-30
IL115972A (en) 2000-09-28
USRE37971E1 (en) 2003-01-28
CO4520285A1 (es) 1997-10-15
MX9703506A (es) 1997-07-31
CZ287731B6 (en) 2001-01-17
ATE328902T1 (de) 2006-06-15
NO972185L (no) 1997-05-13
CN1171742A (zh) 1998-01-28
AU691066B2 (en) 1998-05-07
HUT77737A (hu) 1998-07-28
WO1996015803A1 (en) 1996-05-30
NZ297256A (en) 2000-01-28
NO972185D0 (no) 1997-05-13
EP1227107A1 (en) 2002-07-31
EP0712862A2 (en) 1996-05-22
AU7885498A (en) 1998-11-05
HK1014007A1 (en) 1999-09-17
CA2205061A1 (en) 1996-05-30
AU720820B2 (en) 2000-06-15
SI0712862T1 (sl) 2006-10-31
EP0712862A3 (en) 1998-03-04
BR9509652A (pt) 1997-09-16
CZ145697A3 (en) 1997-12-17
HU217585B (hu) 2000-02-28
DE69535031T2 (de) 2006-12-28
TR199501421A2 (tr) 1996-06-21
US5646242A (en) 1997-07-08
ES2264124T3 (es) 2006-12-16
RU2155773C2 (ru) 2000-09-10
PL320556A1 (en) 1997-10-13
JPH10509176A (ja) 1998-09-08
AU4237296A (en) 1996-06-17
YU71495A (sh) 1998-09-18
DE69535031D1 (de) 2006-07-20
IL115972A0 (en) 1996-01-31
DK0712862T3 (da) 2006-09-25
ZA959680B (en) 1997-05-14
JP4312828B2 (ja) 2009-08-12
EP0712862B1 (en) 2006-06-07
IN179820B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-12-13

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