MX9703506A - Acilacion selectiva de grupos epsilon-amino. - Google Patents
Acilacion selectiva de grupos epsilon-amino.Info
- Publication number
- MX9703506A MX9703506A MX9703506A MX9703506A MX9703506A MX 9703506 A MX9703506 A MX 9703506A MX 9703506 A MX9703506 A MX 9703506A MX 9703506 A MX9703506 A MX 9703506A MX 9703506 A MX9703506 A MX 9703506A
- Authority
- MX
- Mexico
- Prior art keywords
- epsilon
- amino groups
- selective acylation
- acylation
- free
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invencion se refiere a la acilacion de proteínas. Más particularmente, la invencion se refiere a un proceso de un solo paso para acilar selectivamente el grupo E-amino libre de la insulina, análogo de la insulina o proinsulina en presencia de un grupo (alfa)-amino libre.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/341,231 US5646242A (en) | 1994-11-17 | 1994-11-17 | Selective acylation of epsilon-amino groups |
| US08341231 | 1994-11-17 | ||
| PCT/US1995/014872 WO1996015803A1 (en) | 1994-11-17 | 1995-11-14 | SELECTIVE ACYLATION OF ε-AMINO GROUPS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9703506A true MX9703506A (es) | 1997-07-31 |
| MXPA97003506A MXPA97003506A (es) | 1997-12-01 |
Family
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Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |