HU187393B - Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents - Google Patents
Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents Download PDFInfo
- Publication number
- HU187393B HU187393B HU813777A HU377781A HU187393B HU 187393 B HU187393 B HU 187393B HU 813777 A HU813777 A HU 813777A HU 377781 A HU377781 A HU 377781A HU 187393 B HU187393 B HU 187393B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- pyrido
- compound
- alkyl
- product
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30508081A | 1981-09-24 | 1981-09-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
HU187393B true HU187393B (en) | 1985-12-28 |
Family
ID=23179241
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU813777A HU187393B (en) | 1981-09-24 | 1981-12-15 | Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents |
HU843212A HU189426B (en) | 1981-09-24 | 1981-12-15 | Process for producing /2-/amino-piridil/-amino-fenil/-aril-methanon derivatives |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU843212A HU189426B (en) | 1981-09-24 | 1981-12-15 | Process for producing /2-/amino-piridil/-amino-fenil/-aril-methanon derivatives |
Country Status (27)
Country | Link |
---|---|
JP (1) | JPS5865290A (de) |
KR (1) | KR890000764B1 (de) |
BE (1) | BE891666A (de) |
CA (1) | CA1199324A (de) |
CH (1) | CH651833A5 (de) |
DE (1) | DE3150522A1 (de) |
DK (3) | DK186282A (de) |
EG (1) | EG15904A (de) |
ES (6) | ES8303348A1 (de) |
FI (1) | FI71935C (de) |
FR (1) | FR2515183B1 (de) |
GR (1) | GR78473B (de) |
HU (2) | HU187393B (de) |
IE (1) | IE52493B1 (de) |
IL (1) | IL64284A (de) |
IN (1) | IN156080B (de) |
IT (1) | IT1146728B (de) |
LU (1) | LU83865A1 (de) |
NL (1) | NL8200549A (de) |
NO (1) | NO157700C (de) |
NZ (1) | NZ198999A (de) |
PH (2) | PH17847A (de) |
PL (6) | PL139381B1 (de) |
PT (1) | PT74286B (de) |
SE (2) | SE448629B (de) |
YU (1) | YU46128B (de) |
ZA (1) | ZA817866B (de) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3825549A (en) * | 1972-10-24 | 1974-07-23 | Squibb & Sons Inc | Certain dihydropyrido(2,1-b)(1,3)benzodi-azepines and benzodiazocines |
DE2424811C3 (de) * | 1974-05-22 | 1981-08-20 | Dr. Karl Thomae Gmbh, 7950 Biberach | Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
SE422799B (sv) * | 1975-05-28 | 1982-03-29 | Merck & Co Inc | Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner |
-
1981
- 1981-11-05 SE SE8106573A patent/SE448629B/sv not_active IP Right Cessation
- 1981-11-12 ZA ZA817866A patent/ZA817866B/xx unknown
- 1981-11-12 NO NO813839A patent/NO157700C/no unknown
- 1981-11-13 IL IL64284A patent/IL64284A/xx unknown
- 1981-11-13 IN IN1261/CAL/81A patent/IN156080B/en unknown
- 1981-11-17 GR GR66553A patent/GR78473B/el unknown
- 1981-11-18 PH PH26507A patent/PH17847A/en unknown
- 1981-11-25 IE IE2769/81A patent/IE52493B1/en unknown
- 1981-12-09 IT IT68605/81A patent/IT1146728B/it active
- 1981-12-10 FI FI813976A patent/FI71935C/fi not_active IP Right Cessation
- 1981-12-15 HU HU813777A patent/HU187393B/hu not_active IP Right Cessation
- 1981-12-15 ES ES507971A patent/ES8303348A1/es not_active Expired
- 1981-12-15 HU HU843212A patent/HU189426B/hu not_active IP Right Cessation
- 1981-12-21 DE DE19813150522 patent/DE3150522A1/de not_active Withdrawn
- 1981-12-23 PL PL1981241409A patent/PL139381B1/pl unknown
- 1981-12-23 PL PL1981253539A patent/PL143597B1/pl unknown
- 1981-12-23 PL PL1981234426A patent/PL138859B1/pl unknown
- 1981-12-23 PL PL1981253540A patent/PL143322B1/pl unknown
- 1981-12-23 PL PL1981253538A patent/PL143596B1/pl unknown
- 1981-12-23 FR FR8124111A patent/FR2515183B1/fr not_active Expired
- 1981-12-23 PL PL1981241410A patent/PL137068B1/pl unknown
- 1981-12-30 BE BE0/206969A patent/BE891666A/fr not_active IP Right Cessation
-
1982
- 1982-01-05 LU LU83865A patent/LU83865A1/fr unknown
- 1982-01-12 EG EG11/82A patent/EG15904A/xx active
- 1982-01-14 JP JP57004813A patent/JPS5865290A/ja active Pending
- 1982-01-15 PT PT74286A patent/PT74286B/pt unknown
- 1982-01-18 CA CA000394367A patent/CA1199324A/en not_active Expired
- 1982-02-02 KR KR8200420A patent/KR890000764B1/ko active
- 1982-02-12 NL NL8200549A patent/NL8200549A/nl not_active Application Discontinuation
- 1982-02-18 NZ NZ198999A patent/NZ198999A/en unknown
- 1982-03-23 YU YU62582A patent/YU46128B/sh unknown
- 1982-04-15 CH CH2288/82A patent/CH651833A5/fr not_active IP Right Cessation
- 1982-04-26 DK DK186282A patent/DK186282A/da not_active Application Discontinuation
- 1982-09-29 ES ES516052A patent/ES8402295A1/es not_active Expired
- 1982-09-29 ES ES516051A patent/ES8308563A1/es not_active Expired
-
1983
- 1983-10-19 ES ES526563A patent/ES8604531A1/es not_active Expired
- 1983-10-19 ES ES526562A patent/ES526562A0/es active Granted
-
1984
- 1984-08-17 PH PH31120A patent/PH20536A/en unknown
-
1985
- 1985-05-21 ES ES543328A patent/ES8607726A1/es not_active Expired
-
1986
- 1986-02-17 SE SE8600688A patent/SE455305B/sv not_active IP Right Cessation
-
1987
- 1987-08-03 DK DK403487A patent/DK403487A/da not_active Application Discontinuation
- 1987-08-03 DK DK403387A patent/DK403387D0/da not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HU185089B (en) | Process for producing imidazo-diazepine derivatives | |
US3953430A (en) | Substituted benzodiazepin-10-ones and method of use | |
US4192803A (en) | 5H-Pyrrolo[2,1-c][1,4]benzodiazepine derivatives | |
IE922342A1 (en) | Imidazo[2,1-b]benzothiazole-3-acetamide derivatives, their¹preparation and their use in therapeutics | |
AU631982B2 (en) | 5-aryl-4-alkyl-3h-1,2,4-triazole-3-thiones useful as memory enhancers | |
CS259516B2 (en) | Method of new heterocyclic compounds production | |
US4447361A (en) | Aryl substituted pyrido[1,4]benzodiazepines | |
HU202239B (en) | Process for producing benzodiazepine derivatives and pharmaceutical compositions comprising such compounds as active ingredient | |
US3849405A (en) | Thieno-(2,3-e)(1,4)diazepin-2-ones | |
HU187393B (en) | Process for producing phenyl-substitited pyrido-bracket-1,4-bracket closed-benzodiazepines and intermediates and pharmaceutical compositions containing thes as active agents | |
CA1173440A (en) | 2-acyl amino methyl-1,4-benzo diazepine compounds and their acid addition salts, processes for their production, and pharmaceutical compositions containing same | |
KR850000452B1 (ko) | 카바모일옥시아미노-1, 4-벤조디아제핀의 제조방법 | |
CA1087182A (en) | Substituted 1-piperazinyl-triazolo-thieno-1,4- diazepines | |
EP0076017B1 (de) | Phenyl-substituierte Pyrido(1,4)benzodiazepine und Zwischenverbindungen | |
HU186028B (en) | Process for preparing pyrrolo-benzoidiazepines | |
US4556667A (en) | Aryl substituted pyrido[1,4]benzodiazepines and their use as antidepressives | |
JP2001512731A (ja) | AMPA/Kainate受容体阻害剤としての1,3−ジオキソロ/4,5−H/2,3/ベンゾジアゼピン誘導体 | |
US4668675A (en) | 2-[(amino-pyridinyl)amine]phenyl]aryl methanones, their thioxomethyl, ketal or thioketal analogs | |
US5037833A (en) | N-[substituted alkylidene]fused-bicycloalkylidene quinolinamines useful for enhancing the cholinergic function in a mammal | |
JPS584771A (ja) | (5−アミノ−1,3−ジアルキルピラゾ−ル−4−イル)(アリ−ル)メタノンの塩基性アシルアミド類 | |
CS209929B2 (en) | Method of making the new substituted 4h-s-triazolo/3,4c/-thieno/2,3e/-1,4 diazepins | |
US3947447A (en) | 5H-aminoacetamido-10,11-dihydrodibenz-[b,f]azepines and immediate precursors | |
US4007272A (en) | Substituted benzodiazepin-10-ones in treating pain and depression | |
EP0726257B1 (de) | 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung | |
FI77232C (fi) | SOM MELLANPRODUKT VID FRAMSTAELLNING AV 6-FENYL-11H-PYRIDO/2,3-B//1,4/BENTSODIAZEPINER ANVAENDBARA 2-/(3-AMINO-2-PYRIDINYL)AMINO/FENYLARYLMETANONDERIVAT. SIIRRETTY PAEIVAEMAEAERAE-FOERSKJUTET DATUM PL 14 ç 10.06.82. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |