HRP930953B1 - Antihypertensive combination - Google Patents

Antihypertensive combination

Info

Publication number
HRP930953B1
HRP930953B1 HR930953A HRP930953A HRP930953B1 HR P930953 B1 HRP930953 B1 HR P930953B1 HR 930953 A HR930953 A HR 930953A HR P930953 A HRP930953 A HR P930953A HR P930953 B1 HRP930953 B1 HR P930953B1
Authority
HR
Croatia
Prior art keywords
atoms
phenyl
alkyl
radical
halogen
Prior art date
Application number
HR930953A
Other languages
English (en)
Inventor
Jean-Paul Clozel
Rita Mueller
Wolfgang Osterrieder
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HRP930953A2 publication Critical patent/HRP930953A2/hr
Publication of HRP930953B1 publication Critical patent/HRP930953B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Plant Substances (AREA)
  • External Artificial Organs (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR930953A 1991-07-23 1993-06-07 Antihypertensive combination HRP930953B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH219191 1991-07-23

Publications (2)

Publication Number Publication Date
HRP930953A2 HRP930953A2 (en) 1995-10-31
HRP930953B1 true HRP930953B1 (en) 2003-06-30

Family

ID=4228024

Family Applications (1)

Application Number Title Priority Date Filing Date
HR930953A HRP930953B1 (en) 1991-07-23 1993-06-07 Antihypertensive combination

Country Status (31)

Country Link
US (1) US5620975A (cs)
EP (1) EP0524512B1 (cs)
JP (1) JPH0680009B2 (cs)
KR (1) KR100260479B1 (cs)
CN (1) CN1040505C (cs)
AT (1) ATE260661T1 (cs)
AU (1) AU656207B2 (cs)
BG (1) BG60949B1 (cs)
BR (1) BR9202830A (cs)
CA (1) CA2074039C (cs)
CZ (1) CZ281691B6 (cs)
DE (1) DE59209993D1 (cs)
DK (1) DK0524512T3 (cs)
ES (1) ES2215160T3 (cs)
HR (1) HRP930953B1 (cs)
HU (1) HU214029B (cs)
IE (1) IE922378A1 (cs)
IL (1) IL102541A (cs)
IS (1) IS3887A (cs)
MX (1) MX9204212A (cs)
MY (1) MY118064A (cs)
NO (1) NO301047B1 (cs)
NZ (1) NZ243577A (cs)
PT (1) PT524512E (cs)
RO (1) RO110905B (cs)
RU (1) RU2084225C1 (cs)
SK (1) SK278918B6 (cs)
TW (1) TW216770B (cs)
UY (1) UY23449A1 (cs)
YU (2) YU72392A (cs)
ZA (1) ZA925322B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59409631D1 (de) * 1993-07-15 2001-02-15 Hoffmann La Roche Pharmazeutische Kombination, die einen Hemmer des Renin-Angiotensin-Systems und einen Endothelin-Antagonisten enthält
IL131816A (en) 1997-04-04 2003-06-24 Exxon Res & Engineering Compan Composite structures having high containment strength
WO2003031415A1 (en) 2001-10-10 2003-04-17 Aryx Therapeutics Mibefradil-based compounds as calcium channel blockers useful in the treatment of hypertension and angina
US7687086B1 (en) 2003-02-28 2010-03-30 University Of Portland Method for obtaining taxanes
EP2537534B1 (en) 2011-06-22 2014-12-17 Hexal AG Esters of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their therapeutic use.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
CA1319144C (en) * 1986-11-14 1993-06-15 Quirico Branca Tetrahydronaphthalene derivatives
FR2607004B1 (fr) * 1986-11-20 1990-06-01 Synthelabo Compositions pharmaceutiques contenant du diltiazem et un inhibiteur de l'enzyme de conversion de l'angiotensine
US5110813A (en) * 1987-09-15 1992-05-05 Alcoholism And Drug Addiction Research Foundation Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors
US4871731A (en) * 1987-10-07 1989-10-03 Marion Laboratories, Inc. Captopril and diltiazem composition and the like
KR940005408B1 (ko) * 1990-12-03 1994-06-18 만도기계 주식회사 파워 윈도우 모우터 회전자의 선단부 흔들림 측정장치

Also Published As

Publication number Publication date
DE59209993D1 (de) 2004-04-08
EP0524512A2 (de) 1993-01-27
CZ227092A3 (en) 1993-02-17
NO922903L (no) 1993-01-25
RO110905B (ro) 1996-05-30
HRP930953A2 (en) 1995-10-31
IE922378A1 (en) 1993-01-27
AU2041692A (en) 1993-01-28
KR100260479B1 (ko) 2000-07-01
SK227092A3 (en) 1996-02-07
MY118064A (en) 2004-08-30
ES2215160T3 (es) 2004-10-01
HUT62792A (en) 1993-06-28
NZ243577A (en) 1994-09-27
BR9202830A (pt) 1993-03-23
UY23449A1 (es) 1993-01-21
JPH0680009B2 (ja) 1994-10-12
HU9202367D0 (en) 1992-10-28
MX9204212A (es) 1993-08-01
BG60949B1 (bg) 1996-07-31
TW216770B (cs) 1993-12-01
RU2084225C1 (ru) 1997-07-20
EP0524512A3 (en) 1993-09-01
YU49198B (sh) 2004-09-03
ZA925322B (en) 1993-03-31
EP0524512B1 (de) 2004-03-03
IS3887A (is) 1993-01-24
US5620975A (en) 1997-04-15
YU72392A (sh) 1997-05-28
CA2074039A1 (en) 1993-01-24
DK0524512T3 (da) 2004-07-05
CA2074039C (en) 2004-11-02
CN1068737A (zh) 1993-02-10
PT524512E (pt) 2004-07-30
CN1040505C (zh) 1998-11-04
IL102541A (en) 1995-12-08
CZ281691B6 (cs) 1996-12-11
IL102541A0 (en) 1993-01-14
ATE260661T1 (de) 2004-03-15
SK278918B6 (sk) 1998-04-08
KR930001910A (ko) 1993-02-22
JPH05194217A (ja) 1993-08-03
NO301047B1 (no) 1997-09-08
NO922903D0 (no) 1992-07-22
AU656207B2 (en) 1995-01-27
HU214029B (en) 1997-12-29

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Legal Events

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Payment date: 20040727

Year of fee payment: 12

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Effective date: 20050609