HRP20251505T1 - Protutijelo protiv aktivinskog receptora tipa ii za upotrebu u liječenju zatajenja srca - Google Patents

Protutijelo protiv aktivinskog receptora tipa ii za upotrebu u liječenju zatajenja srca

Info

Publication number
HRP20251505T1
HRP20251505T1 HRP20251505TT HRP20251505T HRP20251505T1 HR P20251505 T1 HRP20251505 T1 HR P20251505T1 HR P20251505T T HRP20251505T T HR P20251505TT HR P20251505 T HRP20251505 T HR P20251505T HR P20251505 T1 HRP20251505 T1 HR P20251505T1
Authority
HR
Croatia
Prior art keywords
seq
sequence
chain variable
variable region
heavy chain
Prior art date
Application number
HRP20251505TT
Other languages
English (en)
Croatian (hr)
Inventor
Anthony Rosenzweig
Jason D. Roh
David Glass
Original Assignee
Novartis Ag
Beth Israel Deaconess Medical Center, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Beth Israel Deaconess Medical Center, Inc. filed Critical Novartis Ag
Publication of HRP20251505T1 publication Critical patent/HRP20251505T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HRP20251505TT 2017-03-24 2018-03-20 Protutijelo protiv aktivinskog receptora tipa ii za upotrebu u liječenju zatajenja srca HRP20251505T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762476054P 2017-03-24 2017-03-24
EP18719334.7A EP3600415B1 (en) 2017-03-24 2018-03-20 Antibody against activin receptor type ii receptor for use in treating heart failure
PCT/US2018/023390 WO2018175460A1 (en) 2017-03-24 2018-03-20 Methods for preventing and treating heart disease

Publications (1)

Publication Number Publication Date
HRP20251505T1 true HRP20251505T1 (hr) 2026-01-02

Family

ID=62028095

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20251505TT HRP20251505T1 (hr) 2017-03-24 2018-03-20 Protutijelo protiv aktivinskog receptora tipa ii za upotrebu u liječenju zatajenja srca

Country Status (18)

Country Link
US (3) US10982000B2 (https=)
EP (2) EP4678660A3 (https=)
JP (2) JP7339159B2 (https=)
KR (2) KR102628323B1 (https=)
CN (2) CN119971025A (https=)
AU (1) AU2018240117B2 (https=)
CA (1) CA3054837A1 (https=)
DK (1) DK3600415T3 (https=)
ES (1) ES3054462T3 (https=)
FI (1) FI3600415T3 (https=)
HR (1) HRP20251505T1 (https=)
IL (1) IL269083B2 (https=)
LT (1) LT3600415T (https=)
PL (1) PL3600415T3 (https=)
PT (1) PT3600415T (https=)
RS (1) RS67504B1 (https=)
SI (1) SI3600415T1 (https=)
WO (1) WO2018175460A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI3600415T3 (fi) 2017-03-24 2025-12-05 Novartis Ag Aktiviinireseptorin tyypin ii reseptorin vastainen vasta-aine käytettäväksi sydämen vajaatoiminnan hoidossa
AU2020284038A1 (en) * 2019-05-30 2021-12-02 Acceleron Pharma Inc. ActRII-binding proteins and uses thereof
EP4142769A4 (en) * 2020-04-28 2024-05-15 Acceleron Pharma Inc. ACTRII PROTEINS AND USE IN THE TREATMENT OF POSTCAPILLARY PULMONARY HYPERTENSION
CN111870685B (zh) * 2020-07-16 2022-11-29 上海市同仁医院 运动相关多肽在制备防治缺血性心脏病药物中的应用
IL300362A (en) * 2020-08-20 2023-04-01 Regeneron Pharma Methods to prevent and treat poor cardiac function and covid-19 with activin A antagonists
TW202417505A (zh) * 2022-08-26 2024-05-01 美商維紗妮絲生物公司 Actrii抗體固定單位劑量治療
WO2025026353A1 (en) * 2023-08-01 2025-02-06 Laekna Therapeutics Shanghai Co., Ltd. Anti-acvr2b antibodies and uses thereof
WO2025183966A1 (en) 2024-02-28 2025-09-04 Versanis Bio, Inc. Actrii antibodies with extended half life

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Also Published As

Publication number Publication date
JP7339159B2 (ja) 2023-09-05
EP4678660A2 (en) 2026-01-14
IL269083A (en) 2019-11-28
AU2018240117B2 (en) 2024-12-05
CN119971025A (zh) 2025-05-13
FI3600415T3 (fi) 2025-12-05
ES3054462T3 (en) 2026-02-03
PL3600415T3 (pl) 2026-02-16
IL269083B1 (en) 2024-08-01
KR102628323B1 (ko) 2024-01-22
CA3054837A1 (en) 2018-09-27
PT3600415T (pt) 2025-11-24
US20240158514A1 (en) 2024-05-16
US20200031940A1 (en) 2020-01-30
US20210309749A1 (en) 2021-10-07
IL269083B2 (en) 2024-12-01
JP2023100919A (ja) 2023-07-19
RU2019129858A (ru) 2021-03-23
DK3600415T3 (da) 2025-12-01
CN110461359B (zh) 2025-01-21
AU2018240117A1 (en) 2019-09-19
EP3600415B1 (en) 2025-09-17
WO2018175460A1 (en) 2018-09-27
SI3600415T1 (sl) 2026-01-30
US10982000B2 (en) 2021-04-20
US11834508B2 (en) 2023-12-05
EP4678660A3 (en) 2026-04-01
EP3600415A1 (en) 2020-02-05
JP2020511502A (ja) 2020-04-16
RS67504B1 (sr) 2025-12-31
KR20190131096A (ko) 2019-11-25
CN110461359A (zh) 2019-11-15
KR20240014600A (ko) 2024-02-01
RU2019129858A3 (https=) 2022-03-24
LT3600415T (lt) 2025-12-29

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