JP2011504501A5 - - Google Patents
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- Publication number
- JP2011504501A5 JP2011504501A5 JP2010534969A JP2010534969A JP2011504501A5 JP 2011504501 A5 JP2011504501 A5 JP 2011504501A5 JP 2010534969 A JP2010534969 A JP 2010534969A JP 2010534969 A JP2010534969 A JP 2010534969A JP 2011504501 A5 JP2011504501 A5 JP 2011504501A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nos
- cdr sequences
- cdr
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US403707P | 2007-11-21 | 2007-11-21 | |
| US61/004,037 | 2007-11-21 | ||
| PCT/US2008/012987 WO2009070243A2 (en) | 2007-11-21 | 2008-11-21 | Wise binding agents and epitopes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014061293A Division JP2014167002A (ja) | 2007-11-21 | 2014-03-25 | Wise結合抗体及びエピトープ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011504501A JP2011504501A (ja) | 2011-02-10 |
| JP2011504501A5 true JP2011504501A5 (https=) | 2012-01-12 |
| JP5583591B2 JP5583591B2 (ja) | 2014-09-03 |
Family
ID=40524859
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010534969A Expired - Fee Related JP5583591B2 (ja) | 2007-11-21 | 2008-11-21 | Wise結合抗体及びエピトープ |
| JP2014061293A Withdrawn JP2014167002A (ja) | 2007-11-21 | 2014-03-25 | Wise結合抗体及びエピトープ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014061293A Withdrawn JP2014167002A (ja) | 2007-11-21 | 2014-03-25 | Wise結合抗体及びエピトープ |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8043620B2 (https=) |
| EP (1) | EP2220118A2 (https=) |
| JP (2) | JP5583591B2 (https=) |
| KR (1) | KR20100099193A (https=) |
| CN (1) | CN101925611A (https=) |
| AU (1) | AU2008330125B2 (https=) |
| BR (1) | BRPI0820387A2 (https=) |
| CA (1) | CA2705879A1 (https=) |
| CO (1) | CO6311002A2 (https=) |
| CR (1) | CR11523A (https=) |
| EA (1) | EA201000844A1 (https=) |
| IL (1) | IL205569A0 (https=) |
| MA (1) | MA31918B1 (https=) |
| MX (1) | MX2010005656A (https=) |
| TN (1) | TN2010000213A1 (https=) |
| WO (1) | WO2009070243A2 (https=) |
| ZA (1) | ZA201003578B (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1771470B1 (en) | 2004-07-23 | 2013-06-26 | Acceleron Pharma Inc. | Actrii receptor polypeptides, methods and compositions |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| KR20190006086A (ko) | 2005-11-23 | 2019-01-16 | 악셀레론 파마 인코포레이티드 | 액티빈-actrⅱa 길항제 및 골 성장을 촉진하기 위한 이들의 용도 |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| EP2111229B1 (en) | 2007-02-01 | 2013-04-10 | Acceleron Pharma, Inc. | Pharmaceutical compositions comprising Activin-ActRIIA antagonists for use in preventing or treating breast cancer metastasis or breast cancer related bone loss |
| TWI782836B (zh) | 2007-02-02 | 2022-11-01 | 美商艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
| ES2756725T3 (es) | 2007-02-09 | 2020-04-27 | Acceleron Pharma Inc | Composiciones farmacéuticas que comprenden antagonistas de Activina-ActRIIA |
| EP3243524A1 (en) | 2007-09-18 | 2017-11-15 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion |
| SMT202300222T1 (it) | 2008-08-14 | 2023-09-06 | Acceleron Pharma Inc | Trappole di gdf |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| US8138142B2 (en) | 2009-01-13 | 2012-03-20 | Acceleron Pharma Inc. | Methods for increasing adiponectin in a patient in need thereof |
| BRPI1010587A2 (pt) | 2009-06-08 | 2019-04-09 | Acceleron Pharma Inc. | métodos para aumentar adipócitos termogênicos |
| EP2440577A4 (en) | 2009-06-12 | 2013-01-23 | Acceleron Pharma Inc | SHORTEN ACTRIIB FC FUSION PROTEINS |
| WO2011025964A2 (en) | 2009-08-29 | 2011-03-03 | Abbott Laboratories | Therapeutic dll4 binding proteins |
| JP6267425B2 (ja) | 2009-11-17 | 2018-01-24 | アクセルロン ファーマ, インコーポレイテッド | 筋ジストロフィー治療のためのユートロフィン誘導に関するactriibタンパク質およびその改変体およびその使用 |
| CA2818237C (en) | 2009-11-18 | 2021-05-18 | University Of Medicine And Dentistry Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| US9849192B2 (en) | 2009-11-18 | 2017-12-26 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| EP2507381A4 (en) * | 2009-12-04 | 2016-07-20 | Hoffmann La Roche | MULTISPECIFIC ANTIBODIES, ANTIBODY ANALOGS, COMPOSITIONS AND METHODS |
| WO2011075636A2 (en) | 2009-12-18 | 2011-06-23 | Amgen Inc. | Wise binding agents and epitopes |
| BR112012021941A2 (pt) * | 2010-03-02 | 2022-02-01 | Abbvie Inc | Proteínas terapêuticas de ligação a dll4 |
| CN103298832A (zh) | 2010-11-08 | 2013-09-11 | 阿塞勒隆制药公司 | Actriia结合剂及其用途 |
| JP2015502356A (ja) * | 2011-11-30 | 2015-01-22 | ウェルスタット ダイアグノスティクス,エルエルシー | 5−fuに関連するアッセイ、抗体、免疫原および組成物 |
| TW201333040A (zh) * | 2012-01-06 | 2013-08-16 | Bioalliance Cv | 抗-輸鐵蛋白受器之抗體及其使用方法 |
| FR2987293B1 (fr) * | 2012-02-27 | 2014-03-07 | Michelin & Cie | Procede et appareil pour realiser des objets tridimensionnels a proprietes ameliorees |
| CA2887037A1 (en) * | 2012-10-02 | 2014-04-10 | Rutgers, The State University Of New Jersey | Specific delivery of toxins conjugated with antibodies to activated matriptase |
| NZ707477A (en) | 2012-11-02 | 2019-09-27 | Celgene Corp | Activin-actrii antagonists and uses for treating bone and other disorders |
| BR112015010360A8 (pt) * | 2012-11-08 | 2018-01-16 | Eleven Biotherapeutics Inc | antagonistas de il-6 e utilização dos mesmos. |
| US20140171356A1 (en) * | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| CA2922937A1 (en) | 2013-09-05 | 2015-03-12 | Duke University | Nav1.7 antibodies and methods of using the same |
| US10035847B2 (en) | 2013-10-02 | 2018-07-31 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
| WO2015192111A1 (en) | 2014-06-13 | 2015-12-17 | Acceleron Pharma, Inc. | Methods and compositions for treating ulcers |
| MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
| PT3215530T (pt) | 2014-11-07 | 2019-11-21 | Sesen Bio Inc | Anticorpos de il-6 melhorados |
| JP2018501307A (ja) | 2014-12-03 | 2018-01-18 | セルジーン コーポレイション | アクチビン−ActRIIアンタゴニスト及び貧血を治療するための使用 |
| EP3419599A4 (en) | 2016-02-23 | 2019-09-11 | Sesen Bio, Inc. | IL-6 ANTAGONIST FORMULATIONS AND USE THEREOF |
| JP7145374B2 (ja) | 2016-03-18 | 2022-10-03 | ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー | インビボでの切断可能連結部分によって抗マトリプターゼ抗体にコンジュゲートされた化学療法剤を用いる腫瘍細胞の標的化 |
| EP3448875A4 (en) * | 2016-04-29 | 2020-04-08 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| AU2018205484B2 (en) * | 2017-01-06 | 2024-11-21 | Sixal, Inc. | Therapeutic anti-lgE antibodies and methods and compositions thereof |
| CN118909118A (zh) * | 2017-09-07 | 2024-11-08 | 奥古斯塔大学研究所公司 | 程序性细胞死亡蛋白1抗体 |
| US20220259298A1 (en) * | 2019-07-12 | 2022-08-18 | Kyoto University | Neutralizing Antibody for Tooth Regeneration Treatment Targeting USAG-1 Molecule |
| CN112180099B (zh) * | 2020-09-15 | 2022-07-29 | 江南大学附属医院 | 子宫内膜异位症血清标志物的应用 |
| JP2025504020A (ja) | 2022-01-28 | 2025-02-06 | ジョージアミューン・インコーポレイテッド | Pd-1アゴニストであるプログラム細胞死タンパク質1に対する抗体 |
| CN115322258B (zh) * | 2022-05-31 | 2024-08-13 | 武汉真福医药股份有限公司 | 一种单克隆抗体qkma-1g41及其应用 |
| CN115304677B (zh) * | 2022-06-19 | 2024-08-16 | 湖北真福医药有限公司 | 一种抗枯草芽孢杆菌纤溶酶的单克隆抗体qkma-9a10及应用 |
| CN116712533B (zh) * | 2023-07-03 | 2024-02-02 | 广东暨安特博生物科技有限公司 | 一种sostdc1蛋白在制备治疗皮肤病产品中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2220912A1 (en) * | 1995-06-05 | 1996-12-12 | Gregg A. Hastings | Human ccn-like growth factor |
| CA2416538A1 (en) * | 2000-07-20 | 2002-01-31 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| US20040023356A1 (en) * | 2002-06-14 | 2004-02-05 | Robb Krumlauf | Wise/Sost nucleic acid sequences and amino acid sequences |
| US20060002929A1 (en) * | 2004-03-23 | 2006-01-05 | Khare Sanjay D | Monoclonal antibodies |
| WO2009131553A2 (en) * | 2006-12-29 | 2009-10-29 | Osteogenex Inc. | Methods of altering bone growth by administration of sost or wise antagonist or agonist |
| HRP20131167T1 (hr) * | 2007-06-18 | 2014-01-03 | Merck Sharp & Dohme B.V. | Antitijela za humani receptor programirane smrti pd-1 |
| JO3382B1 (ar) * | 2008-12-23 | 2019-03-13 | Amgen Inc | أجسام مضادة ترتبط مع مستقبل cgrp بشري |
| PE20120475A1 (es) * | 2009-05-12 | 2012-05-05 | Pfizer | Anticuerpos especificos para dkk-1 |
-
2008
- 2008-11-21 CN CN2008801252375A patent/CN101925611A/zh active Pending
- 2008-11-21 MX MX2010005656A patent/MX2010005656A/es active IP Right Grant
- 2008-11-21 WO PCT/US2008/012987 patent/WO2009070243A2/en not_active Ceased
- 2008-11-21 CA CA2705879A patent/CA2705879A1/en not_active Abandoned
- 2008-11-21 EA EA201000844A patent/EA201000844A1/ru unknown
- 2008-11-21 AU AU2008330125A patent/AU2008330125B2/en not_active Ceased
- 2008-11-21 EP EP08855691A patent/EP2220118A2/en not_active Withdrawn
- 2008-11-21 BR BRPI0820387-3A patent/BRPI0820387A2/pt not_active IP Right Cessation
- 2008-11-21 KR KR1020107013609A patent/KR20100099193A/ko not_active Withdrawn
- 2008-11-21 JP JP2010534969A patent/JP5583591B2/ja not_active Expired - Fee Related
- 2008-11-21 US US12/275,850 patent/US8043620B2/en not_active Expired - Fee Related
-
2010
- 2010-05-05 IL IL205569A patent/IL205569A0/en unknown
- 2010-05-14 TN TN2010000213A patent/TN2010000213A1/fr unknown
- 2010-05-20 ZA ZA2010/03578A patent/ZA201003578B/en unknown
- 2010-06-15 MA MA32918A patent/MA31918B1/fr unknown
- 2010-06-21 CR CR11523A patent/CR11523A/es not_active Application Discontinuation
- 2010-06-23 CO CO10075718A patent/CO6311002A2/es not_active Application Discontinuation
-
2011
- 2011-09-15 US US13/233,983 patent/US8309092B2/en active Active
-
2014
- 2014-03-25 JP JP2014061293A patent/JP2014167002A/ja not_active Withdrawn
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