JP2025036561A5 - - Google Patents
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- JP2025036561A5 JP2025036561A5 JP2024228911A JP2024228911A JP2025036561A5 JP 2025036561 A5 JP2025036561 A5 JP 2025036561A5 JP 2024228911 A JP2024228911 A JP 2024228911A JP 2024228911 A JP2024228911 A JP 2024228911A JP 2025036561 A5 JP2025036561 A5 JP 2025036561A5
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- JP
- Japan
- Prior art keywords
- amino acid
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- acid sequence
- set forth
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015187488 | 2015-09-24 | ||
| JP2015187488 | 2015-09-24 | ||
| JP2021075739A JP7137657B2 (ja) | 2015-09-24 | 2021-04-28 | 抗ｇａｒｐ抗体 |
| JP2022140119A JP2022169801A (ja) | 2015-09-24 | 2022-09-02 | 抗ｇａｒｐ抗体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022140119A Division JP2022169801A (ja) | 2015-09-24 | 2022-09-02 | 抗ｇａｒｐ抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025036561A JP2025036561A (ja) | 2025-03-14 |
| JP2025036561A5 true JP2025036561A5 (https=) | 2025-04-17 |
Family
ID=58386752
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540925A Active JP6878283B2 (ja) | 2015-09-24 | 2016-09-23 | 抗ｇａｒｐ抗体 |
| JP2020164126A Active JP6868739B2 (ja) | 2015-09-24 | 2020-09-29 | 抗ｇａｒｐ抗体 |
| JP2021075739A Active JP7137657B2 (ja) | 2015-09-24 | 2021-04-28 | 抗ｇａｒｐ抗体 |
| JP2022140119A Pending JP2022169801A (ja) | 2015-09-24 | 2022-09-02 | 抗ｇａｒｐ抗体 |
| JP2024228911A Pending JP2025036561A (ja) | 2015-09-24 | 2024-12-25 | 抗ｇａｒｐ抗体 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540925A Active JP6878283B2 (ja) | 2015-09-24 | 2016-09-23 | 抗ｇａｒｐ抗体 |
| JP2020164126A Active JP6868739B2 (ja) | 2015-09-24 | 2020-09-29 | 抗ｇａｒｐ抗体 |
| JP2021075739A Active JP7137657B2 (ja) | 2015-09-24 | 2021-04-28 | 抗ｇａｒｐ抗体 |
| JP2022140119A Pending JP2022169801A (ja) | 2015-09-24 | 2022-09-02 | 抗ｇａｒｐ抗体 |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | US11046780B2 (https=) |
| EP (3) | EP4349997A3 (https=) |
| JP (5) | JP6878283B2 (https=) |
| KR (2) | KR20250037587A (https=) |
| CN (3) | CN110922481A (https=) |
| AU (3) | AU2016325858B2 (https=) |
| BR (1) | BR112018005777A2 (https=) |
| CA (1) | CA2999819A1 (https=) |
| CO (1) | CO2018003542A2 (https=) |
| DK (1) | DK3354729T5 (https=) |
| ES (1) | ES2978126T3 (https=) |
| FI (1) | FI3354729T3 (https=) |
| HR (1) | HRP20240495T1 (https=) |
| HU (1) | HUE066594T2 (https=) |
| IL (3) | IL288784B2 (https=) |
| LT (1) | LT3354729T (https=) |
| MX (2) | MX2018003594A (https=) |
| MY (1) | MY194586A (https=) |
| PH (1) | PH12018500642A1 (https=) |
| PL (1) | PL3354729T3 (https=) |
| PT (1) | PT3354729T (https=) |
| RS (1) | RS65415B1 (https=) |
| RU (2) | RU2022108079A (https=) |
| SG (2) | SG11201802352VA (https=) |
| SI (1) | SI3354729T1 (https=) |
| SM (1) | SMT202400160T1 (https=) |
| TW (3) | TWI909341B (https=) |
| WO (1) | WO2017051888A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015015003A1 (en) | 2013-08-01 | 2015-02-05 | Université Catholique de Louvain | Anti-garp protein and uses thereof |
| EA201792573A1 (ru) | 2015-05-21 | 2018-04-30 | Харпун Терапьютикс, Инк. | Триспецифические связанные белки и способы их применения |
| TWI909341B (zh) | 2015-09-24 | 2025-12-21 | 日商第一三共股份有限公司 | 抗garp抗體及其製造方法及用途 |
| US11046782B2 (en) * | 2016-03-30 | 2021-06-29 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| JP7101621B2 (ja) | 2016-05-20 | 2022-07-15 | ハープーン セラピューティクス，インク． | 単一ドメイン血清アルブミン結合タンパク質 |
| KR102379464B1 (ko) | 2016-06-20 | 2022-03-29 | 키맵 리미티드 | 항-pd-l1 항체 |
| GB201707561D0 (en) * | 2017-05-11 | 2017-06-28 | Argenx Bvba | GARP-TGF-beta antibodies |
| AU2018265856B2 (en) | 2017-05-12 | 2023-04-27 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
| IL315737A (en) | 2017-10-13 | 2024-11-01 | Harpoon Therapeutics Inc | B-cell maturation antigen-binding proteins |
| HRP20241268T1 (hr) | 2017-10-13 | 2024-12-06 | Harpoon Therapeutics, Inc. | Trispecifični proteini i postupci primjene |
| WO2019118513A1 (en) | 2017-12-12 | 2019-06-20 | Pionyr Immunotherapeutics, Inc. | Anti-trem2 antibodies and related methods |
| CA3099900A1 (en) * | 2018-05-31 | 2019-12-05 | Daiichi Sankyo Company, Limited | Anti-human tlr7 antibody |
| WO2020061482A1 (en) | 2018-09-21 | 2020-03-26 | Harpoon Therapeutics, Inc. | Egfr binding proteins and methods of use |
| SG11202103022WA (en) | 2018-09-25 | 2021-04-29 | Harpoon Therapeutics Inc | Dll3 binding proteins and methods of use |
| WO2021024020A1 (en) | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
| EP4049675A4 (en) * | 2019-10-25 | 2023-11-22 | Daiichi Sankyo Company, Limited | COMBINATION OF ANTI-GARP ANTIBODIES AND IMMUNE REGULATOR |
| WO2021231732A1 (en) | 2020-05-15 | 2021-11-18 | Bristol-Myers Squibb Company | Antibodies to garp |
| MX2023000197A (es) | 2020-07-07 | 2023-02-22 | BioNTech SE | Arn terapeutico para el cancer positivo para vph. |
| WO2022116877A1 (en) | 2020-12-02 | 2022-06-09 | Shanghai Henlius Biotech, Inc. | ANTI-GARP/TGFβ ANTIBODIES AND METHODS OF USE |
| WO2022135666A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Treatment schedule for cytokine proteins |
| TW202245808A (zh) | 2020-12-21 | 2022-12-01 | 德商拜恩迪克公司 | 用於治療癌症之治療性ｒｎａ |
| WO2022135667A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Therapeutic rna for treating cancer |
| CA3204628A1 (en) | 2021-01-13 | 2022-07-21 | John T. POIRIER | Antibody-pyrrolobenzodiazepine derivative conjugate |
| TW202245844A (zh) | 2021-01-13 | 2022-12-01 | 紀念斯隆凱特琳癌症中心 | 抗dll3抗體-藥物結合物 |
| CA3208624A1 (en) * | 2021-01-18 | 2022-07-21 | Shanghai Jemincare Pharmaceutical Co., Ltd. | Garp protein antibody and application thereof |
| JP2024525758A (ja) | 2021-07-13 | 2024-07-12 | ビオンテック・ソシエタス・エウロパエア | がんのための併用療法におけるｃｄ４０およびｃｄ１３７に対する多重特異性結合剤 |
| TW202333802A (zh) | 2021-10-11 | 2023-09-01 | 德商拜恩迪克公司 | 用於肺癌之治療性rna(二) |
| JP2025526336A (ja) | 2022-07-22 | 2025-08-13 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Ｔ細胞悪性腫瘍におけるバイオマーカー及びバイオターゲットとしてのｇａｒｐ |
| KR20250120305A (ko) | 2022-12-14 | 2025-08-08 | 아스텔라스 파마 유럽 비.브이. | Cldn18.2 및 cd3에 결합하는 2중 특이성 결합제와 면역 체크포인트 저해제를 수반한 조합 요법 |
| US20250002588A1 (en) | 2023-04-07 | 2025-01-02 | Diagonal Therapeutics Inc. | Bispecific agonistic antibodies to activin a receptor like type 1 (alk1) |
| AR134560A1 (es) | 2023-12-08 | 2026-01-28 | Astellas Pharma Inc | Terapia de combinación que implica agentes de unión biespecíficos que se unen a cldn18.2 y cd3 y agentes que estabilizan o aumentan la expresión de cldn18.2 |
| WO2026033885A1 (en) | 2024-08-08 | 2026-02-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120866A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120867A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies |
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| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| EP0585287B1 (en) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| AU665025B2 (en) | 1991-09-23 | 1995-12-14 | Cambridge Antibody Technology Limited | Production of chimeric antibodies - a combinatorial approach |
| ES2341666T3 (es) | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| DE69333823T2 (de) | 1992-03-24 | 2006-05-04 | Cambridge Antibody Technology Ltd., Melbourn | Verfahren zur herstellung von gliedern von spezifischen bindungspaaren |
| GB9313509D0 (en) | 1993-06-30 | 1993-08-11 | Medical Res Council | Chemisynthetic libraries |
| EP0731842A1 (en) | 1993-12-03 | 1996-09-18 | Medical Research Council | Recombinant binding proteins and peptides |
| ES2434961T5 (es) | 1998-04-20 | 2018-01-18 | Roche Glycart Ag | Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo |
| CZ302070B6 (cs) | 1998-04-21 | 2010-09-29 | Micromet Ag | Jednoretezcový multifunkcní polypeptid, polynukleotid, vektor obsahující tento polynukleotid, bunka transfekovaná tímto polynukleotidem, prostredek obsahující tento polypeptid, polynukleotid nebo vektor a jejich použití a zpusob identifikace aktiváto |
| EP1176195B1 (en) | 1999-04-09 | 2013-05-22 | Kyowa Hakko Kirin Co., Ltd. | Method for controlling the activity of immunologically functional molecule |
| CN1333274A (zh) * | 2000-07-07 | 2002-01-30 | 上海博德基因开发有限公司 | 一种新的多肽——人garp蛋白12.98和编码这种多肽的多核苷酸 |
| ES2639222T5 (es) | 2000-10-06 | 2023-11-24 | Kyowa Kirin Co Ltd | Células que producen unas composiciones de anticuerpo |
| CN100506277C (zh) | 2001-11-01 | 2009-07-01 | Uab研究基金会 | 肿瘤坏死因子相关细胞凋亡诱导配体受体的选择性抗体和其它治疗剂的联合体系 |
| ES2273202T3 (es) | 2003-01-07 | 2007-05-01 | Symphogen A/S | Procedimiento para producir proteinas policlonales recombinantes. |
| WO2006089678A2 (en) | 2005-02-22 | 2006-08-31 | Bioinvent International Ab | Antibodies and peptides binding to hiv tat, and uses thereof |
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| WO2007113301A1 (en) | 2006-04-03 | 2007-10-11 | Medizinische Hochschule Hannover | Pharmaceuticals for influencing the reaction of the human immune system |
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| CA2711806A1 (en) | 2008-01-11 | 2009-07-16 | Morphosys Ag | Display vectors and methods and uses thereof |
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| US20100260668A1 (en) | 2008-04-29 | 2010-10-14 | Abbott Laboratories | Dual Variable Domain Immunoglobulins and Uses Thereof |
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| BRPI1013428A2 (pt) | 2009-05-11 | 2019-07-02 | U3 Pharma Gmbh | anticorpos humanizados para axl |
| CA2794196A1 (en) | 2010-03-23 | 2011-09-29 | Intrexon Corporation | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
| NZ610153A (en) | 2010-10-29 | 2014-07-25 | Daiichi Sankyo Co Ltd | Novel anti-dr5 antibody |
| US8440797B2 (en) | 2010-12-06 | 2013-05-14 | Dainippon Sumitomo Pharma Co., Ltd. | Human monoclonal antibody |
| SMT201800269T1 (it) * | 2011-04-25 | 2018-07-17 | Daiichi Sankyo Co Ltd | Anticorpo anti-b7-h3 |
| TWI679212B (zh) | 2011-11-15 | 2019-12-11 | 美商安進股份有限公司 | 針對ｂｃｍａ之e3以及ｃｄ３的結合分子 |
| EP2832855A4 (en) | 2012-03-30 | 2016-02-24 | Daiichi Sankyo Co Ltd | NOVEL ANTI-SIGLEC-15 ANTIBODY |
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| JP2014141434A (ja) | 2013-01-24 | 2014-08-07 | Daiichi Sankyo Co Ltd | 抗ｒｏｂｏ４抗体 |
| DK3421486T5 (da) * | 2012-06-22 | 2024-09-16 | The Trustees Of Darthmouth College | Nye Vista-IG-konstruktioner og anvendelse af Vista-IG til behandling af autoimmune, allergiske og inflammatoriske lidelser |
| EP2910573B1 (en) | 2012-10-19 | 2020-02-19 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate produced by binding through linker having hydrophilic structure |
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| WO2015015003A1 (en) * | 2013-08-01 | 2015-02-05 | Université Catholique de Louvain | Anti-garp protein and uses thereof |
| EP2832747A1 (en) * | 2013-08-01 | 2015-02-04 | Université Catholique de Louvain | Anti-GARP protein and uses thereof |
| WO2016125017A1 (en) | 2015-02-03 | 2016-08-11 | Universite Catholique De Louvain | Anti-garp protein and uses thereof |
| TWI909341B (zh) * | 2015-09-24 | 2025-12-21 | 日商第一三共股份有限公司 | 抗garp抗體及其製造方法及用途 |
| US11046782B2 (en) | 2016-03-30 | 2021-06-29 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination |
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2016
- 2016-09-23 TW TW113106312A patent/TWI909341B/zh active
- 2016-09-23 SI SI201631810T patent/SI3354729T1/sl unknown
- 2016-09-23 MX MX2018003594A patent/MX2018003594A/es unknown
- 2016-09-23 RU RU2022108079A patent/RU2022108079A/ru unknown
- 2016-09-23 PL PL16848676.9T patent/PL3354729T3/pl unknown
- 2016-09-23 BR BR112018005777-0A patent/BR112018005777A2/pt active IP Right Grant
- 2016-09-23 KR KR1020257006887A patent/KR20250037587A/ko active Pending
- 2016-09-23 SM SM20240160T patent/SMT202400160T1/it unknown
- 2016-09-23 AU AU2016325858A patent/AU2016325858B2/en active Active
- 2016-09-23 EP EP24157462.3A patent/EP4349997A3/en active Pending
- 2016-09-23 ES ES16848676T patent/ES2978126T3/es active Active
- 2016-09-23 SG SG11201802352VA patent/SG11201802352VA/en unknown
- 2016-09-23 CN CN201911407390.3A patent/CN110922481A/zh active Pending
- 2016-09-23 EP EP19218146.9A patent/EP3660051A1/en active Pending
- 2016-09-23 CN CN202211442176.3A patent/CN115869398B/zh active Active
- 2016-09-23 FI FIEP16848676.9T patent/FI3354729T3/fi active
- 2016-09-23 CA CA2999819A patent/CA2999819A1/en active Pending
- 2016-09-23 KR KR1020187008255A patent/KR102776730B1/ko active Active
- 2016-09-23 HR HRP20240495TT patent/HRP20240495T1/hr unknown
- 2016-09-23 IL IL288784A patent/IL288784B2/en unknown
- 2016-09-23 IL IL302932A patent/IL302932B1/en unknown
- 2016-09-23 MY MYPI2018000433A patent/MY194586A/en unknown
- 2016-09-23 TW TW110146254A patent/TWI836305B/zh active
- 2016-09-23 WO PCT/JP2016/078067 patent/WO2017051888A1/ja not_active Ceased
- 2016-09-23 RS RS20240428A patent/RS65415B1/sr unknown
- 2016-09-23 RU RU2018114904A patent/RU2769379C2/ru active
- 2016-09-23 US US15/761,045 patent/US11046780B2/en active Active
- 2016-09-23 TW TW105130782A patent/TWI751979B/zh active
- 2016-09-23 IL IL258322A patent/IL258322B2/en unknown
- 2016-09-23 JP JP2017540925A patent/JP6878283B2/ja active Active
- 2016-09-23 EP EP16848676.9A patent/EP3354729B1/en active Active
- 2016-09-23 SG SG10201912570UA patent/SG10201912570UA/en unknown
- 2016-09-23 PT PT168486769T patent/PT3354729T/pt unknown
- 2016-09-23 DK DK16848676.9T patent/DK3354729T5/da active
- 2016-09-23 HU HUE16848676A patent/HUE066594T2/hu unknown
- 2016-09-23 CN CN201680056149.9A patent/CN108026521B/zh active Active
- 2016-09-23 LT LTEPPCT/JP2016/078067T patent/LT3354729T/lt unknown
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2018
- 2018-03-22 PH PH12018500642A patent/PH12018500642A1/en unknown
- 2018-03-22 MX MX2023003470A patent/MX2023003470A/es unknown
- 2018-04-03 CO CONC2018/0003542A patent/CO2018003542A2/es unknown
- 2018-07-24 US US16/044,196 patent/US10550198B2/en active Active
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2020
- 2020-02-06 AU AU2020200866A patent/AU2020200866B2/en active Active
- 2020-09-29 JP JP2020164126A patent/JP6868739B2/ja active Active
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2021
- 2021-04-28 JP JP2021075739A patent/JP7137657B2/ja active Active
- 2021-06-28 US US17/361,137 patent/US12006372B2/en active Active
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2022
- 2022-09-02 JP JP2022140119A patent/JP2022169801A/ja active Pending
- 2022-09-14 AU AU2022231706A patent/AU2022231706B2/en active Active
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2024
- 2024-04-30 US US18/650,725 patent/US20240360245A1/en active Pending
- 2024-12-25 JP JP2024228911A patent/JP2025036561A/ja active Pending