JP2022541520A5 - - Google Patents
Info
- Publication number
- JP2022541520A5 JP2022541520A5 JP2022502928A JP2022502928A JP2022541520A5 JP 2022541520 A5 JP2022541520 A5 JP 2022541520A5 JP 2022502928 A JP2022502928 A JP 2022502928A JP 2022502928 A JP2022502928 A JP 2022502928A JP 2022541520 A5 JP2022541520 A5 JP 2022541520A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- composition according
- acid sequence
- seq
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2023505 | 2019-07-15 | ||
| NL2023505 | 2019-07-15 | ||
| PCT/IB2020/056635 WO2021009684A1 (en) | 2019-07-15 | 2020-07-15 | Modified aav capsid proteins for treatment of arthritic disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022541520A JP2022541520A (ja) | 2022-09-26 |
| JP2022541520A5 true JP2022541520A5 (https=) | 2023-07-21 |
| JP7681277B2 JP7681277B2 (ja) | 2025-05-22 |
Family
ID=68425203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502928A Active JP7681277B2 (ja) | 2019-07-15 | 2020-07-15 | 関節炎疾患の治療のための修飾ａａｖキャプシドタンパク質 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20220267797A1 (https=) |
| EP (1) | EP3999119B1 (https=) |
| JP (1) | JP7681277B2 (https=) |
| KR (1) | KR20220081971A (https=) |
| CN (1) | CN114502737B (https=) |
| AU (1) | AU2020314883A1 (https=) |
| BR (1) | BR112022000724A2 (https=) |
| CA (1) | CA3146791A1 (https=) |
| DK (1) | DK3999119T3 (https=) |
| ES (1) | ES2998884T3 (https=) |
| FI (1) | FI3999119T3 (https=) |
| HR (1) | HRP20241647T1 (https=) |
| HU (1) | HUE069369T2 (https=) |
| IL (1) | IL289826A (https=) |
| LT (1) | LT3999119T (https=) |
| MX (1) | MX2022000551A (https=) |
| PH (1) | PH12022550109A1 (https=) |
| PL (1) | PL3999119T3 (https=) |
| PT (1) | PT3999119T (https=) |
| RS (1) | RS66255B1 (https=) |
| SI (1) | SI3999119T1 (https=) |
| SM (1) | SMT202400486T1 (https=) |
| WO (1) | WO2021009684A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3740222T1 (sl) * | 2018-01-17 | 2023-11-30 | Meiragtx Uk Ii Limited | Modificiran kapsidni protein raav za gensko terapijo |
| KR20240095539A (ko) | 2021-10-08 | 2024-06-25 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 변이체 및 이의 사용 방법 |
| AU2022423978A1 (en) * | 2021-12-28 | 2024-07-18 | Chengdu Origen Biotechnology Co., Ltd. | Modified aav capsid protein and use thereof |
| WO2024191778A1 (en) | 2023-03-10 | 2024-09-19 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2024213660A1 (en) | 2023-04-13 | 2024-10-17 | Meiragtx Uk Ii Limited | Inflammation-inducible promoters |
| AU2024332181A1 (en) | 2023-08-31 | 2026-02-12 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003042361A2 (en) | 2001-11-09 | 2003-05-22 | Government Of The United States Of America, Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| ES2525067T3 (es) * | 2005-04-07 | 2014-12-17 | The Trustees Of The University Of Pennsylvania | Método de incremento de la función de un vector de AAV |
| EP2311966A3 (en) | 2005-10-20 | 2012-09-05 | Amsterdam Molecular Therapeutics (AMT) B.V. | Improved AAV vectors produced in insect cells |
| CN103849629B (zh) | 2006-06-21 | 2017-06-09 | 尤尼克尔Ip股份有限公司 | 具有经修饰的用于在昆虫细胞中产生aav的aav‑rep78翻译起始密码子的载体 |
| WO2008024998A2 (en) | 2006-08-24 | 2008-02-28 | Virovek, Inc. | Expression in insect cells of genes with overlapping open reading frames, methods and compositions therefor |
| EP2012122A1 (en) * | 2007-07-06 | 2009-01-07 | Medigene AG | Mutated parvovirus structural proteins as vaccines |
| DK2173888T3 (en) | 2007-07-26 | 2016-11-28 | Uniqure Ip Bv | Baculovirus vectors comprising repeating coding sequences WITH differential preferred codons |
| JP2011512156A (ja) | 2008-02-19 | 2011-04-21 | アムステルダム モレキュラー セラピューティクス ビー．ブイ． | 昆虫細胞におけるパルボウイルスｒｅｐ及びｃａｐタンパク質の発現の最適化 |
| WO2009154452A1 (en) | 2008-06-17 | 2009-12-23 | Amsterdam Molecular Therapeutics B.V. | Parvoviral capsid with incorporated Gly-Ala repeat region |
| EP2545165B1 (en) | 2010-03-11 | 2020-07-29 | uniQure IP B.V. | Mutated rep encoding sequences for use in aav production |
| JP6198278B2 (ja) | 2011-09-08 | 2017-09-20 | ユニキュアー アイピー ビー．ブイ． | Ａａｖ調製物からの混入ウイルスの除去 |
| WO2013174760A1 (en) | 2012-05-25 | 2013-11-28 | Deutsches Krebsforschungszentrum | Optimized aav-vectors for high transduction rates in dendritic cells |
| GB201403684D0 (en) * | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| EP3204503A1 (en) | 2014-10-06 | 2017-08-16 | Arthrogen BV | Aav-based gene therapy |
| US11364308B2 (en) * | 2016-05-13 | 2022-06-21 | 4D Molecular Therapeutics Inc. | Adeno-associated virus variant capsids and methods of use thereof |
| JP7165410B2 (ja) * | 2016-08-19 | 2022-11-04 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイティド | 組換え自己相補的アデノ随伴ウイルスを使用して疾患を治療するための方法及び組成物 |
| KR20190088561A (ko) * | 2016-12-07 | 2019-07-26 | 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 | 인터류킨-1 수용체 길항제(IL-1RA) cDNA |
| EP3609542B1 (en) * | 2017-04-11 | 2023-02-22 | Ruprecht-Karls-Universität Heidelberg | Adeno-associated virus library |
| SI3740222T1 (sl) * | 2018-01-17 | 2023-11-30 | Meiragtx Uk Ii Limited | Modificiran kapsidni protein raav za gensko terapijo |
-
2020
- 2020-07-15 MX MX2022000551A patent/MX2022000551A/es unknown
- 2020-07-15 DK DK20740418.7T patent/DK3999119T3/da active
- 2020-07-15 HR HRP20241647TT patent/HRP20241647T1/hr unknown
- 2020-07-15 FI FIEP20740418.7T patent/FI3999119T3/fi active
- 2020-07-15 US US17/627,364 patent/US20220267797A1/en active Pending
- 2020-07-15 ES ES20740418T patent/ES2998884T3/es active Active
- 2020-07-15 AU AU2020314883A patent/AU2020314883A1/en not_active Abandoned
- 2020-07-15 RS RS20241346A patent/RS66255B1/sr unknown
- 2020-07-15 SI SI202030519T patent/SI3999119T1/sl unknown
- 2020-07-15 PT PT207404187T patent/PT3999119T/pt unknown
- 2020-07-15 CA CA3146791A patent/CA3146791A1/en active Pending
- 2020-07-15 PH PH1/2022/550109A patent/PH12022550109A1/en unknown
- 2020-07-15 KR KR1020227004437A patent/KR20220081971A/ko active Pending
- 2020-07-15 CN CN202080064732.0A patent/CN114502737B/zh active Active
- 2020-07-15 EP EP20740418.7A patent/EP3999119B1/en active Active
- 2020-07-15 PL PL20740418.7T patent/PL3999119T3/pl unknown
- 2020-07-15 HU HUE20740418A patent/HUE069369T2/hu unknown
- 2020-07-15 BR BR112022000724A patent/BR112022000724A2/pt unknown
- 2020-07-15 SM SM20240486T patent/SMT202400486T1/it unknown
- 2020-07-15 LT LTEPPCT/IB2020/056635T patent/LT3999119T/lt unknown
- 2020-07-15 WO PCT/IB2020/056635 patent/WO2021009684A1/en not_active Ceased
- 2020-07-15 JP JP2022502928A patent/JP7681277B2/ja active Active
-
2022
- 2022-01-13 IL IL289826A patent/IL289826A/en unknown
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