|
US3992518A
(en)
|
1974-10-24 |
1976-11-16 |
G. D. Searle & Co. |
Method for making a microsealed delivery device
|
|
GB1478759A
(en)
|
1974-11-18 |
1977-07-06 |
Alza Corp |
Process for forming outlet passageways in pills using a laser
|
|
US4284444A
(en)
|
1977-08-01 |
1981-08-18 |
Herculite Protective Fabrics Corporation |
Activated polymer materials and process for making same
|
|
US4200098A
(en)
|
1978-10-23 |
1980-04-29 |
Alza Corporation |
Osmotic system with distribution zone for dispensing beneficial agent
|
|
US4200984A
(en)
|
1979-03-12 |
1980-05-06 |
Fink Ray D |
Detachable tool combining bracket and method
|
|
US4398908A
(en)
|
1980-11-28 |
1983-08-16 |
Siposs George G |
Insulin delivery system
|
|
US4435173A
(en)
|
1982-03-05 |
1984-03-06 |
Delta Medical Industries |
Variable rate syringe pump for insulin delivery
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5231112A
(en)
|
1984-04-12 |
1993-07-27 |
The Liposome Company, Inc. |
Compositions containing tris salt of cholesterol hemisuccinate and antifungal
|
|
US5916588A
(en)
|
1984-04-12 |
1999-06-29 |
The Liposome Company, Inc. |
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
|
|
JPS61502760A
(ja)
|
1984-07-24 |
1986-11-27 |
キイ・フア−マシユ−テイカルズ・インコ−ポレイテツド |
粘着性経皮投与層
|
|
US4684479A
(en)
|
1985-08-14 |
1987-08-04 |
Arrigo Joseph S D |
Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
|
|
US6759057B1
(en)
|
1986-06-12 |
2004-07-06 |
The Liposome Company, Inc. |
Methods and compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs
|
|
IE60901B1
(en)
|
1986-08-21 |
1994-08-24 |
Vestar Inc |
Improved treatment of systemic fungal infections with phospholipid particles encapsulating polyene antifungal antibiotics
|
|
US4933185A
(en)
|
1986-09-24 |
1990-06-12 |
Massachusetts Institute Of Technology |
System for controlled release of biologically active compounds
|
|
US6406713B1
(en)
|
1987-03-05 |
2002-06-18 |
The Liposome Company, Inc. |
Methods of preparing low-toxicity drug-lipid complexes
|
|
US4976696A
(en)
|
1987-08-10 |
1990-12-11 |
Becton, Dickinson And Company |
Syringe pump and the like for delivering medication
|
|
US4861800A
(en)
|
1987-08-18 |
1989-08-29 |
Buyske Donald A |
Method for administering the drug deprenyl so as to minimize the danger of side effects
|
|
AU598958B2
(en)
|
1987-11-12 |
1990-07-05 |
Vestar, Inc. |
Improved amphotericin b liposome preparation
|
|
GB8807504D0
(en)
|
1988-03-29 |
1988-05-05 |
Sandoz Ltd |
Improvements in/relating to organic compounds
|
|
JP2717808B2
(ja)
|
1988-08-10 |
1998-02-25 |
テルモ株式会社 |
シリンジポンプ
|
|
US5534617A
(en)
|
1988-10-28 |
1996-07-09 |
Genentech, Inc. |
Human growth hormone variants having greater affinity for human growth hormone receptor at site 1
|
|
US5017378A
(en)
|
1989-05-01 |
1991-05-21 |
The University Of Virginia Alumni Patents Foundation |
Intraorgan injection of biologically active compounds contained in slow-release microcapsules or microspheres
|
|
US5298022A
(en)
|
1989-05-29 |
1994-03-29 |
Amplifon Spa |
Wearable artificial pancreas
|
|
US5318540A
(en)
|
1990-04-02 |
1994-06-07 |
Pharmetrix Corporation |
Controlled release infusion device
|
|
US5492534A
(en)
|
1990-04-02 |
1996-02-20 |
Pharmetrix Corporation |
Controlled release portable pump
|
|
US5176502A
(en)
|
1990-04-25 |
1993-01-05 |
Becton, Dickinson And Company |
Syringe pump and the like for delivering medication
|
|
US5215680A
(en)
|
1990-07-10 |
1993-06-01 |
Cavitation-Control Technology, Inc. |
Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
|
|
US5206161A
(en)
|
1991-02-01 |
1993-04-27 |
Genentech, Inc. |
Human plasma carboxypeptidase B
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
US5573776A
(en)
|
1992-12-02 |
1996-11-12 |
Alza Corporation |
Oral osmotic device with hydrogel driving member
|
|
US6491916B1
(en)
|
1994-06-01 |
2002-12-10 |
Tolerance Therapeutics, Inc. |
Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies
|
|
US5885573A
(en)
|
1993-06-01 |
1999-03-23 |
Arch Development Corporation |
Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
|
|
US5660848A
(en)
|
1994-11-02 |
1997-08-26 |
The Population Council, Center For Biomedical Research |
Subdermally implantable device
|
|
CA2263455C
(en)
|
1996-08-23 |
2002-10-29 |
Sequus Pharmaceuticals, Inc. |
Liposomes containing a cisplatin compound
|
|
US6056973A
(en)
|
1996-10-11 |
2000-05-02 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method of preparation
|
|
EP0932390A1
(en)
|
1996-10-11 |
1999-08-04 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method
|
|
SK283760B6
(sk)
|
1996-10-15 |
2004-01-08 |
The Liposome Company, Inc. |
Farmaceutický prostriedok na dopravu bioaktívnych látok
|
|
US6361796B1
(en)
|
1996-10-25 |
2002-03-26 |
Shire Laboratories, Inc. |
Soluble form osmotic dose delivery system
|
|
ATE314054T1
(de)
|
1996-10-25 |
2006-01-15 |
Shire Lab Inc |
Osmotisches verabreichungssystem für lösliche dosen
|
|
WO1998052976A1
(en)
|
1997-05-21 |
1998-11-26 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
|
DE19747261A1
(de)
|
1997-10-25 |
1999-04-29 |
Bayer Ag |
Osmotisches Arzneimittelfreisetzungssystem
|
|
DE69838526T2
(de)
|
1998-02-05 |
2008-07-03 |
Biosense Webster, Inc., Diamond Bar |
Gerät zum Freisetzen eines Medikaments im Herzen
|
|
US6406632B1
(en)
|
1998-04-03 |
2002-06-18 |
Symyx Technologies, Inc. |
Rapid characterization of polymers
|
|
GB9815157D0
(en)
|
1998-07-13 |
1998-09-09 |
Metron Designs Ltd |
High resolution pulse width setting from relatively low frequency clocks
|
|
US6713086B2
(en)
|
1998-12-18 |
2004-03-30 |
Abbott Laboratories |
Controlled release formulation of divalproex sodium
|
|
NZ514442A
(en)
|
1999-03-03 |
2003-08-29 |
Optinose As |
Nasal delivery device
|
|
US6183770B1
(en)
|
1999-04-15 |
2001-02-06 |
Acutek International |
Carrier patch for the delivery of agents to the skin
|
|
US6743211B1
(en)
|
1999-11-23 |
2004-06-01 |
Georgia Tech Research Corporation |
Devices and methods for enhanced microneedle penetration of biological barriers
|
|
US6352721B1
(en)
|
2000-01-14 |
2002-03-05 |
Osmotica Corp. |
Combined diffusion/osmotic pumping drug delivery system
|
|
US20030228309A1
(en)
|
2000-11-08 |
2003-12-11 |
Theodora Salcedo |
Antibodies that immunospecifically bind to TRAIL receptors
|
|
IN190699B
(https=)
|
2001-02-02 |
2003-08-16 |
Sun Pharmaceutical Ind Ltd |
|
|
WO2002079415A2
(en)
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
|
US6890918B2
(en)
|
2001-04-30 |
2005-05-10 |
Shire Laboratories, Inc. |
Pharmaceutical compositions including ACE/NEP inhibitors and bioavailability enhancers
|
|
US6838093B2
(en)
|
2001-06-01 |
2005-01-04 |
Shire Laboratories, Inc. |
System for osmotic delivery of pharmaceutically active agents
|
|
KR100407467B1
(ko)
|
2001-07-12 |
2003-11-28 |
최수봉 |
리모컨 방식의 인슐린 자동주사기
|
|
US6945952B2
(en)
|
2002-06-25 |
2005-09-20 |
Theraject, Inc. |
Solid solution perforator for drug delivery and other applications
|
|
US7294513B2
(en)
|
2002-07-24 |
2007-11-13 |
Wyatt Technology Corporation |
Method and apparatus for characterizing solutions of small particles
|
|
JP5139800B2
(ja)
|
2004-06-03 |
2013-02-06 |
ノビミューン エスアー |
抗ｃｄ３抗体およびその使用方法
|
|
AR057807A1
(es)
|
2005-09-12 |
2007-12-19 |
Novimmune Sa |
Formulaciones de anticuerpo anti-cd3
|
|
NZ591087A
(en)
|
2008-10-01 |
2012-08-31 |
Micromet Ag |
Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxc d3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody
|
|
US8703717B2
(en)
|
2009-02-03 |
2014-04-22 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
|
CA2748314C
(en)
|
2009-02-03 |
2018-10-02 |
Amunix Operating Inc. |
Extended recombinant polypeptides and compositions comprising same
|
|
US8680050B2
(en)
|
2009-02-03 |
2014-03-25 |
Amunix Operating Inc. |
Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
|
|
JP5839597B2
(ja)
|
2009-06-08 |
2016-01-06 |
アムニクス オペレーティング インコーポレイテッド |
グルコース調節ポリペプチド並びにその作成及び使用方法
|
|
SI2440241T1
(sl)
|
2009-06-08 |
2017-11-30 |
Amunix Operating Inc. |
Polipeptidni rastni hormoni in postopki za njihovo izdelavo in uporabo
|
|
AU2010290131C1
(en)
|
2009-08-24 |
2015-12-03 |
Amunix Operating Inc. |
Coagulation factor VII compositions and methods of making and using same
|
|
WO2011028344A2
(en)
|
2009-08-25 |
2011-03-10 |
Amunix Operating Inc. |
Interleukin-1 receptor antagonist compositions and methods of making and using same
|
|
WO2011123830A2
(en)
|
2010-04-02 |
2011-10-06 |
Amunix Operating Inc. |
Alpha 1-antitrypsin compositions and methods of making and using same
|
|
EP2552967A4
(en)
|
2010-04-02 |
2014-10-08 |
Amunix Operating Inc |
BINDING FUSION PROTEINS, BINDING FUSION PROTEIN MEDICINAL CONJUGATES, XTEN MEDICAMENT CONJUGATES, AND METHOD FOR THEIR PREPARATION AND USE
|
|
HRP20200007T1
(hr)
|
2012-07-11 |
2020-03-20 |
Bioverativ Therapeutics Inc. |
Kompleks proteina faktora viii s xten i von willebrandovim faktorom, te njegova uporaba
|
|
US10548953B2
(en)
|
2013-08-14 |
2020-02-04 |
Bioverativ Therapeutics Inc. |
Factor VIII-XTEN fusions and uses thereof
|
|
MX2017006016A
(es)
*
|
2014-11-11 |
2017-06-19 |
Amunix Operating Inc |
Composiciones conjugadas de xten direccionadas y metodos para producir las mismas.
|
|
IL319047A
(en)
|
2015-08-28 |
2025-04-01 |
Amunix Operating Inc |
Chimeric polypeptide composition and methods for its preparation and use
|
|
EP3728326A4
(en)
*
|
2017-12-21 |
2021-12-15 |
Amunix Pharmaceuticals, Inc. |
SEPARATING SEGMENTS AND BINDING COMPOSITIONS THEREFORE
|
|
SG11202007572VA
(en)
*
|
2018-02-15 |
2020-09-29 |
Macrogenics Inc |
Variant cd3-binding domains and their use in combination therapies for the treatment of disease
|
|
US20230121775A1
(en)
*
|
2019-06-26 |
2023-04-20 |
Amunix Pharmaceuticals, Inc. |
Cd3 antigen binding fragments and compositions comprising same
|
|
CA3143522A1
(en)
|
2019-06-26 |
2020-12-30 |
Amunix Pharmaceuticals, Inc. |
Egfr antigen binding fragments and compositions comprising same
|
|
CN115175920B
(zh)
*
|
2019-11-13 |
2025-10-31 |
阿穆尼克斯制药公司 |
加条形码的xten多肽及其组合物以及其制备和使用方法
|
|
JP2023531494A
(ja)
|
2020-06-25 |
2023-07-24 |
アムニクス ファーマシューティカルズ， インコーポレイテッド |
Ｈｅｒ－２標的化二重特異性組成物ならびにその作製および使用のための方法
|