RS67504B1 - Antitelo protiv aktivin receptora tipa ii za upotrebu u lečenju srčane insuficijencije - Google Patents

Antitelo protiv aktivin receptora tipa ii za upotrebu u lečenju srčane insuficijencije

Info

Publication number
RS67504B1
RS67504B1 RS20251180A RSP20251180A RS67504B1 RS 67504 B1 RS67504 B1 RS 67504B1 RS 20251180 A RS20251180 A RS 20251180A RS P20251180 A RSP20251180 A RS P20251180A RS 67504 B1 RS67504 B1 RS 67504B1
Authority
RS
Serbia
Prior art keywords
seq
chain variable
variable region
light chain
heavy chain
Prior art date
Application number
RS20251180A
Other languages
English (en)
Serbian (sr)
Inventor
Anthony Rosenzweig
Jason D Roh
David J Glass
Original Assignee
Novartis Ag
Beth Israel Deaconess Medical Ct Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Beth Israel Deaconess Medical Ct Inc filed Critical Novartis Ag
Publication of RS67504B1 publication Critical patent/RS67504B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20251180A 2017-03-24 2018-03-20 Antitelo protiv aktivin receptora tipa ii za upotrebu u lečenju srčane insuficijencije RS67504B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762476054P 2017-03-24 2017-03-24
EP18719334.7A EP3600415B1 (en) 2017-03-24 2018-03-20 Antibody against activin receptor type ii receptor for use in treating heart failure
PCT/US2018/023390 WO2018175460A1 (en) 2017-03-24 2018-03-20 Methods for preventing and treating heart disease

Publications (1)

Publication Number Publication Date
RS67504B1 true RS67504B1 (sr) 2025-12-31

Family

ID=62028095

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20251180A RS67504B1 (sr) 2017-03-24 2018-03-20 Antitelo protiv aktivin receptora tipa ii za upotrebu u lečenju srčane insuficijencije

Country Status (18)

Country Link
US (3) US10982000B2 (https=)
EP (2) EP4678660A3 (https=)
JP (2) JP7339159B2 (https=)
KR (2) KR102628323B1 (https=)
CN (2) CN119971025A (https=)
AU (1) AU2018240117B2 (https=)
CA (1) CA3054837A1 (https=)
DK (1) DK3600415T3 (https=)
ES (1) ES3054462T3 (https=)
FI (1) FI3600415T3 (https=)
HR (1) HRP20251505T1 (https=)
IL (1) IL269083B2 (https=)
LT (1) LT3600415T (https=)
PL (1) PL3600415T3 (https=)
PT (1) PT3600415T (https=)
RS (1) RS67504B1 (https=)
SI (1) SI3600415T1 (https=)
WO (1) WO2018175460A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI3600415T3 (fi) 2017-03-24 2025-12-05 Novartis Ag Aktiviinireseptorin tyypin ii reseptorin vastainen vasta-aine käytettäväksi sydämen vajaatoiminnan hoidossa
AU2020284038A1 (en) * 2019-05-30 2021-12-02 Acceleron Pharma Inc. ActRII-binding proteins and uses thereof
EP4142769A4 (en) * 2020-04-28 2024-05-15 Acceleron Pharma Inc. ACTRII PROTEINS AND USE IN THE TREATMENT OF POSTCAPILLARY PULMONARY HYPERTENSION
CN111870685B (zh) * 2020-07-16 2022-11-29 上海市同仁医院 运动相关多肽在制备防治缺血性心脏病药物中的应用
IL300362A (en) * 2020-08-20 2023-04-01 Regeneron Pharma Methods to prevent and treat poor cardiac function and covid-19 with activin A antagonists
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WO2025026353A1 (en) * 2023-08-01 2025-02-06 Laekna Therapeutics Shanghai Co., Ltd. Anti-acvr2b antibodies and uses thereof
WO2025183966A1 (en) 2024-02-28 2025-09-04 Versanis Bio, Inc. Actrii antibodies with extended half life

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Also Published As

Publication number Publication date
JP7339159B2 (ja) 2023-09-05
EP4678660A2 (en) 2026-01-14
IL269083A (en) 2019-11-28
AU2018240117B2 (en) 2024-12-05
CN119971025A (zh) 2025-05-13
FI3600415T3 (fi) 2025-12-05
ES3054462T3 (en) 2026-02-03
PL3600415T3 (pl) 2026-02-16
IL269083B1 (en) 2024-08-01
KR102628323B1 (ko) 2024-01-22
CA3054837A1 (en) 2018-09-27
PT3600415T (pt) 2025-11-24
US20240158514A1 (en) 2024-05-16
US20200031940A1 (en) 2020-01-30
US20210309749A1 (en) 2021-10-07
IL269083B2 (en) 2024-12-01
HRP20251505T1 (hr) 2026-01-02
JP2023100919A (ja) 2023-07-19
RU2019129858A (ru) 2021-03-23
DK3600415T3 (da) 2025-12-01
CN110461359B (zh) 2025-01-21
AU2018240117A1 (en) 2019-09-19
EP3600415B1 (en) 2025-09-17
WO2018175460A1 (en) 2018-09-27
SI3600415T1 (sl) 2026-01-30
US10982000B2 (en) 2021-04-20
US11834508B2 (en) 2023-12-05
EP4678660A3 (en) 2026-04-01
EP3600415A1 (en) 2020-02-05
JP2020511502A (ja) 2020-04-16
KR20190131096A (ko) 2019-11-25
CN110461359A (zh) 2019-11-15
KR20240014600A (ko) 2024-02-01
RU2019129858A3 (https=) 2022-03-24
LT3600415T (lt) 2025-12-29

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