LT3600415T - Antikūnas prieš ii tipo aktivino receptorių, skirtas naudoti širdies nepakankamumo gydymui - Google Patents

Antikūnas prieš ii tipo aktivino receptorių, skirtas naudoti širdies nepakankamumo gydymui

Info

Publication number
LT3600415T
LT3600415T LTEPPCT/US2018/023390T LTUS2018023390T LT3600415T LT 3600415 T LT3600415 T LT 3600415T LT US2018023390 T LTUS2018023390 T LT US2018023390T LT 3600415 T LT3600415 T LT 3600415T
Authority
LT
Lithuania
Prior art keywords
receptor
heart failure
antibody against
treating heart
against activin
Prior art date
Application number
LTEPPCT/US2018/023390T
Other languages
English (en)
Lithuanian (lt)
Inventor
Anthony Rosenzweig
Jason Roh
David Glass
Original Assignee
Novartis Ag
Beth Israel Deaconess Medical Center, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Beth Israel Deaconess Medical Center, Inc. filed Critical Novartis Ag
Publication of LT3600415T publication Critical patent/LT3600415T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEPPCT/US2018/023390T 2017-03-24 2018-03-20 Antikūnas prieš ii tipo aktivino receptorių, skirtas naudoti širdies nepakankamumo gydymui LT3600415T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762476054P 2017-03-24 2017-03-24
PCT/US2018/023390 WO2018175460A1 (en) 2017-03-24 2018-03-20 Methods for preventing and treating heart disease

Publications (1)

Publication Number Publication Date
LT3600415T true LT3600415T (lt) 2025-12-29

Family

ID=62028095

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2018/023390T LT3600415T (lt) 2017-03-24 2018-03-20 Antikūnas prieš ii tipo aktivino receptorių, skirtas naudoti širdies nepakankamumo gydymui

Country Status (18)

Country Link
US (3) US10982000B2 (https=)
EP (2) EP3600415B1 (https=)
JP (2) JP7339159B2 (https=)
KR (2) KR102628323B1 (https=)
CN (2) CN119971025A (https=)
AU (1) AU2018240117B2 (https=)
CA (1) CA3054837A1 (https=)
DK (1) DK3600415T3 (https=)
ES (1) ES3054462T3 (https=)
FI (1) FI3600415T3 (https=)
HR (1) HRP20251505T1 (https=)
IL (1) IL269083B2 (https=)
LT (1) LT3600415T (https=)
PL (1) PL3600415T3 (https=)
PT (1) PT3600415T (https=)
RS (1) RS67504B1 (https=)
SI (1) SI3600415T1 (https=)
WO (1) WO2018175460A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3600415T (lt) 2017-03-24 2025-12-29 Novartis Ag Antikūnas prieš ii tipo aktivino receptorių, skirtas naudoti širdies nepakankamumo gydymui
JP7669291B2 (ja) * 2019-05-30 2025-04-28 アクセレロン ファーマ インコーポレーテッド Ａｃｔｒｉｉ結合性タンパク質及びその使用
US20230174620A1 (en) * 2020-04-28 2023-06-08 Acceleron Pharma Inc. Actrii proteins and use in treating post-capillary pulmonary hypertension
CN111870685B (zh) * 2020-07-16 2022-11-29 上海市同仁医院 运动相关多肽在制备防治缺血性心脏病药物中的应用
JP2023539107A (ja) * 2020-08-20 2023-09-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッド アクチビンａアンタゴニストによる心機能障害及びｃｏｖｉｄ－１９の予防及び治療方法
JP2025529933A (ja) * 2022-08-26 2025-09-09 バーサニス・バイオ・インコーポレイテッド ＡｃｔＲＩＩ抗体固定単位用量の治療
WO2025026353A1 (en) * 2023-08-01 2025-02-06 Laekna Therapeutics Shanghai Co., Ltd. Anti-acvr2b antibodies and uses thereof
WO2025183966A1 (en) 2024-02-28 2025-09-04 Versanis Bio, Inc. Actrii antibodies with extended half life

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Also Published As

Publication number Publication date
DK3600415T3 (da) 2025-12-01
PT3600415T (pt) 2025-11-24
JP7339159B2 (ja) 2023-09-05
ES3054462T3 (en) 2026-02-03
RS67504B1 (sr) 2025-12-31
CN110461359B (zh) 2025-01-21
KR20240014600A (ko) 2024-02-01
AU2018240117B2 (en) 2024-12-05
JP2020511502A (ja) 2020-04-16
EP3600415B1 (en) 2025-09-17
AU2018240117A1 (en) 2019-09-19
KR102628323B1 (ko) 2024-01-22
PL3600415T3 (pl) 2026-02-16
EP4678660A3 (en) 2026-04-01
IL269083B1 (en) 2024-08-01
EP4678660A2 (en) 2026-01-14
CA3054837A1 (en) 2018-09-27
US11834508B2 (en) 2023-12-05
WO2018175460A1 (en) 2018-09-27
US20200031940A1 (en) 2020-01-30
KR20190131096A (ko) 2019-11-25
HRP20251505T1 (hr) 2026-01-02
RU2019129858A3 (https=) 2022-03-24
US20240158514A1 (en) 2024-05-16
JP2023100919A (ja) 2023-07-19
CN119971025A (zh) 2025-05-13
SI3600415T1 (sl) 2026-01-30
IL269083A (en) 2019-11-28
RU2019129858A (ru) 2021-03-23
CN110461359A (zh) 2019-11-15
FI3600415T3 (fi) 2025-12-05
US10982000B2 (en) 2021-04-20
US20210309749A1 (en) 2021-10-07
EP3600415A1 (en) 2020-02-05
IL269083B2 (en) 2024-12-01

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