JP2020055849A5 - - Google Patents

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Publication number
JP2020055849A5
JP2020055849A5 JP2019220807A JP2019220807A JP2020055849A5 JP 2020055849 A5 JP2020055849 A5 JP 2020055849A5 JP 2019220807 A JP2019220807 A JP 2019220807A JP 2019220807 A JP2019220807 A JP 2019220807A JP 2020055849 A5 JP2020055849 A5 JP 2020055849A5
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JP
Japan
Prior art keywords
tau
binding
seq
amino acid
acid sequence
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Application number
JP2019220807A
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English (en)
Japanese (ja)
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JP2020055849A (ja
JP7100008B2 (ja
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Publication of JP2020055849A5 publication Critical patent/JP2020055849A5/ja
Priority to JP2022105415A priority Critical patent/JP7413448B2/ja
Application granted granted Critical
Publication of JP7100008B2 publication Critical patent/JP7100008B2/ja
Active legal-status Critical Current
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JP2019220807A 2015-07-06 2019-12-06 Tau結合抗体 Active JP7100008B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022105415A JP7413448B2 (ja) 2015-07-06 2022-06-30 Tau結合抗体

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15175522 2015-07-06
EP15175522.0 2015-07-06

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018500423A Division JP6630426B2 (ja) 2015-07-06 2016-07-05 Tau結合抗体

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022105415A Division JP7413448B2 (ja) 2015-07-06 2022-06-30 Tau結合抗体

Publications (3)

Publication Number Publication Date
JP2020055849A JP2020055849A (ja) 2020-04-09
JP2020055849A5 true JP2020055849A5 (https=) 2020-07-02
JP7100008B2 JP7100008B2 (ja) 2022-07-12

Family

ID=53524640

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018500423A Active JP6630426B2 (ja) 2015-07-06 2016-07-05 Tau結合抗体
JP2019220807A Active JP7100008B2 (ja) 2015-07-06 2019-12-06 Tau結合抗体
JP2022105415A Active JP7413448B2 (ja) 2015-07-06 2022-06-30 Tau結合抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2018500423A Active JP6630426B2 (ja) 2015-07-06 2016-07-05 Tau結合抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022105415A Active JP7413448B2 (ja) 2015-07-06 2022-06-30 Tau結合抗体

Country Status (29)

Country Link
US (4) US10287343B2 (https=)
EP (2) EP3319983B1 (https=)
JP (3) JP6630426B2 (https=)
KR (2) KR102770650B1 (https=)
CN (1) CN107849104B (https=)
AR (1) AR105267A1 (https=)
AU (1) AU2016289755C1 (https=)
CA (1) CA2991451A1 (https=)
CL (1) CL2018000043A1 (https=)
CO (1) CO2017012971A2 (https=)
EA (1) EA037092B1 (https=)
EC (1) ECSP18000887A (https=)
ES (1) ES3060419T3 (https=)
HR (1) HRP20260348T1 (https=)
IL (1) IL256685B (https=)
MA (2) MA41670A1 (https=)
MD (1) MD3319983T2 (https=)
MX (1) MX2017015817A (https=)
MY (1) MY193677A (https=)
PE (1) PE20180481A1 (https=)
PH (1) PH12017502207B1 (https=)
SG (1) SG10202010735PA (https=)
SM (1) SMT202600068T1 (https=)
TN (1) TN2017000539A1 (https=)
TW (1) TWI745295B (https=)
UA (1) UA124616C2 (https=)
UY (1) UY36773A (https=)
WO (1) WO2017005734A1 (https=)
ZA (1) ZA201800027B (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ775762A (en) 2015-06-05 2025-02-28 Genentech Inc Anti-tau antibodies and methods of use
WO2017005734A1 (en) 2015-07-06 2017-01-12 Ucb Biopharma Sprl Tau-binding antibodies
US10344081B2 (en) 2015-07-06 2019-07-09 Ucb Biopharma Sprl Tau-binding antibodies
MX2019006330A (es) 2016-12-07 2019-09-26 Genentech Inc Anticuerpos anti-tau y metodos de uso.
UA128383C2 (uk) 2016-12-07 2024-07-03 Дженентек, Інк. Антитіло до тау-білка та спосіб його застосування
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
SG11201907422RA (en) 2017-02-17 2019-09-27 Denali Therapeutics Inc Anti-tau antibodies and methods of use thereof
JP2018139530A (ja) 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
AU2018352308B2 (en) 2017-10-16 2025-06-05 Eisai R&D Management Co., Ltd. Anti-tau antibodies and uses thereof
EP3894438A1 (en) * 2018-12-13 2021-10-20 INSERM (Institut National de la Santé et de la Recherche Médicale) New anti tau svqivykpv epitope single domain antibody
KR20220062287A (ko) * 2019-08-13 2022-05-16 워싱턴 유니버시티 Mtbr 타우 아이소폼 검출 방법 및 이의 용도
CN115335406B (zh) 2020-02-12 2026-01-30 伊莱利利公司 抗体或抗原-结合片段的结晶
CA3183835A1 (en) 2020-06-25 2021-12-30 Jeanne E. Baker High affinity antibodies targeting tau phosphorylated at serine 413
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
KR20250069606A (ko) 2022-09-15 2025-05-19 보이저 테라퓨틱스, 인크. 타우 결합 화합물
EP4619416A1 (en) * 2022-11-14 2025-09-24 Washington University Methods to detect csf mtbr-tau and uses thereof
WO2025122634A1 (en) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
WO2025171285A1 (en) * 2024-02-09 2025-08-14 University Of Notre Dame Du Lac Tau proteomimetics
WO2025196217A1 (en) 2024-03-21 2025-09-25 UCB Biopharma SRL Treatment of tauopathies with tau-binding antibodies
WO2026057816A1 (en) 2024-09-13 2026-03-19 UCB Biopharma SRL Treatment of tauopathies with tau-binding antibodies

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
DK336987D0 (da) 1987-07-01 1987-07-01 Novo Industri As Immobiliseringsmetode
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
GB8719042D0 (en) 1987-08-12 1987-09-16 Parker D Conjugate compounds
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
GB8907617D0 (en) 1989-04-05 1989-05-17 Celltech Ltd Drug delivery system
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
GB9112536D0 (en) 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds
GB9120467D0 (en) 1991-09-26 1991-11-06 Celltech Ltd Anti-hmfg antibodies and process for their production
FR2716640B1 (fr) 1994-02-28 1996-05-03 Procedes Machines Speciales Dispositif de centrage et de blocage d'une pièce en vue de son rodage à l'aide d'un rodoir à expansion.
US6372716B1 (en) 1994-04-26 2002-04-16 Genetics Institute, Inc. Formulations for factor IX
US6685940B2 (en) 1995-07-27 2004-02-03 Genentech, Inc. Protein formulation
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
US6566329B1 (en) 1999-06-28 2003-05-20 Novo Nordisk A/S Freeze-dried preparation of human growth hormone
AT500379B8 (de) 2001-02-02 2009-08-15 Axon Neuroscience Tau-proteine
US6908963B2 (en) 2001-10-09 2005-06-21 Nektar Therapeutics Al, Corporation Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
ES2551439T5 (es) 2003-07-01 2018-11-08 Ucb Biopharma Sprl Fragmentos Fab de anticuerpos modificados
GB0315457D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0315450D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0411186D0 (en) 2004-05-19 2004-06-23 Celltech R&D Ltd Biological products
GB0412181D0 (en) 2004-06-01 2004-06-30 Celltech R&D Ltd Biological products
CN1721437A (zh) * 2004-07-13 2006-01-18 中南大学 一种与Tau蛋白相关的多肽抗原及抗体
NZ612578A (en) 2005-08-19 2014-11-28 Abbvie Inc Dual variable domain immunoglobin and uses thereof
GB0614780D0 (en) 2006-07-25 2006-09-06 Ucb Sa Biological products
GB0619291D0 (en) 2006-09-29 2006-11-08 Ucb Sa Altered antibodies
GB0624500D0 (en) * 2006-12-07 2007-01-17 Istituto Superiore Di Sanito A novel passive vaccine for candida infections
EP2535349A1 (en) 2007-09-26 2012-12-19 UCB Pharma S.A. Dual specificity antibody fusions
CN101307108B (zh) * 2008-06-25 2012-04-04 南京川博生物技术有限公司 抗磷酸化Tau蛋白抗体及其在AD症异常磷酸化Tau蛋白水平测定上的用途
CA2737241C (en) 2008-09-26 2017-08-29 Ucb Pharma S.A. Multivalent antibody fusion proteins
CA2740316A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Conjugates of glp-1 agonists and uses thereof
EP2370472A4 (en) 2008-12-05 2013-04-24 Angiochem Inc LEPTIN AND LEPTIN ANALOGUE CONJUGATES AND ITS USES
CA2745524C (en) 2008-12-05 2020-06-09 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
WO2011030107A1 (en) 2009-09-10 2011-03-17 Ucb Pharma S.A. Multivalent antibodies
AU2010305284A1 (en) 2009-10-06 2012-05-03 Angiochem Inc. Compositions and methods for the transport of therapeutic agents
MY164376A (en) 2010-10-07 2017-12-15 Univ Leuven Kath Phosphospecific antibodies recognizing tau
CA2813493C (en) * 2010-10-11 2019-07-09 University Of Zurich Human anti-tau antibodies
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
ME03008B (me) 2011-09-19 2018-10-20 Axon Neuroscience Se Terapija na osnovu proteina i dijagnoza patologije u којој posreduje tau u alcнajмerovoj bolesti
US20140294724A1 (en) * 2011-10-24 2014-10-02 Intellect Neurosciences, Inc. Compositions and methods for treatment of proteinopathies
WO2013068571A1 (en) 2011-11-11 2013-05-16 Ucb Pharma S.A. Albumin binding antibodies and binding fragments thereof
MX350311B (es) 2011-12-20 2017-09-01 Janssen Biotech Inc Anticuerpos anti-phf-tau y sus usos.
SG10201708959WA (en) * 2012-07-03 2017-11-29 Univ Washington Antibodies to tau
NZ630542A (en) * 2012-08-16 2017-06-30 Ipierian Inc Methods of treating a tauopathy
CA2896066C (en) 2012-12-21 2022-07-12 Biogen Ma Inc. Human anti-tau antibodies
CA2874083C (en) * 2014-12-05 2024-01-02 Universite Laval Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases
US10344081B2 (en) 2015-07-06 2019-07-09 Ucb Biopharma Sprl Tau-binding antibodies
WO2017005734A1 (en) 2015-07-06 2017-01-12 Ucb Biopharma Sprl Tau-binding antibodies

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