MD3319983T2 - Anticorpi de legare a TAU - Google Patents

Anticorpi de legare a TAU

Info

Publication number
MD3319983T2
MD3319983T2 MDE20180496T MDE20180496T MD3319983T2 MD 3319983 T2 MD3319983 T2 MD 3319983T2 MD E20180496 T MDE20180496 T MD E20180496T MD E20180496 T MDE20180496 T MD E20180496T MD 3319983 T2 MD3319983 T2 MD 3319983T2
Authority
MD
Moldova
Prior art keywords
antibodies
tau
binding antibodies
relates
present
Prior art date
Application number
MDE20180496T
Other languages
English (en)
Romanian (ro)
Inventor
David Edward Ormonde Knight
Terence Seward Baker
David James Mcmillan
Robert Anthony Griffin
Georges Mairet-Coello
Patrick Downey
Jean-Philippe Courade
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53524640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD3319983(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of MD3319983T2 publication Critical patent/MD3319983T2/ro

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/524CH2 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/526CH3 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
MDE20180496T 2015-07-06 2016-07-05 Anticorpi de legare a TAU MD3319983T2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15175522 2015-07-06
PCT/EP2016/065813 WO2017005734A1 (en) 2015-07-06 2016-07-05 Tau-binding antibodies

Publications (1)

Publication Number Publication Date
MD3319983T2 true MD3319983T2 (ro) 2026-03-31

Family

ID=53524640

Family Applications (1)

Application Number Title Priority Date Filing Date
MDE20180496T MD3319983T2 (ro) 2015-07-06 2016-07-05 Anticorpi de legare a TAU

Country Status (29)

Country Link
US (4) US10287343B2 (https=)
EP (2) EP3319983B1 (https=)
JP (3) JP6630426B2 (https=)
KR (2) KR102770650B1 (https=)
CN (1) CN107849104B (https=)
AR (1) AR105267A1 (https=)
AU (1) AU2016289755C1 (https=)
CA (1) CA2991451A1 (https=)
CL (1) CL2018000043A1 (https=)
CO (1) CO2017012971A2 (https=)
EA (1) EA037092B1 (https=)
EC (1) ECSP18000887A (https=)
ES (1) ES3060419T3 (https=)
HR (1) HRP20260348T1 (https=)
IL (1) IL256685B (https=)
MA (2) MA41670A1 (https=)
MD (1) MD3319983T2 (https=)
MX (1) MX2017015817A (https=)
MY (1) MY193677A (https=)
PE (1) PE20180481A1 (https=)
PH (1) PH12017502207B1 (https=)
SG (1) SG10202010735PA (https=)
SM (1) SMT202600068T1 (https=)
TN (1) TN2017000539A1 (https=)
TW (1) TWI745295B (https=)
UA (1) UA124616C2 (https=)
UY (1) UY36773A (https=)
WO (1) WO2017005734A1 (https=)
ZA (1) ZA201800027B (https=)

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US10344081B2 (en) 2015-07-06 2019-07-09 Ucb Biopharma Sprl Tau-binding antibodies
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UA128383C2 (uk) 2016-12-07 2024-07-03 Дженентек, Інк. Антитіло до тау-білка та спосіб його застосування
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
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Also Published As

Publication number Publication date
CO2017012971A2 (es) 2018-03-09
TWI745295B (zh) 2021-11-11
MA41670A1 (fr) 2018-05-31
US20190284267A1 (en) 2019-09-19
EA201890172A1 (ru) 2018-10-31
JP2020055849A (ja) 2020-04-09
KR20180025962A (ko) 2018-03-09
TN2017000539A1 (en) 2019-04-12
EA037092B1 (ru) 2021-02-04
MY193677A (en) 2022-10-25
AU2016289755B2 (en) 2020-12-03
TW201713689A (zh) 2017-04-16
CL2018000043A1 (es) 2018-05-18
US20230416350A1 (en) 2023-12-28
EP3319983A1 (en) 2018-05-16
PE20180481A1 (es) 2018-03-07
IL256685B (en) 2022-02-01
US10287343B2 (en) 2019-05-14
PH12017502207A1 (en) 2018-06-11
ZA201800027B (en) 2019-06-26
US20180201666A1 (en) 2018-07-19
EP3319983B1 (en) 2026-01-28
ES3060419T3 (en) 2026-03-26
PH12017502207B1 (en) 2022-08-10
BR112017028102A2 (en) 2018-09-04
UA124616C2 (uk) 2021-10-20
HK1246804A1 (zh) 2018-09-14
ECSP18000887A (es) 2018-03-31
NZ738058A (en) 2021-07-30
SMT202600068T1 (it) 2026-03-09
AU2016289755A1 (en) 2018-01-04
US10889640B2 (en) 2021-01-12
EP3319983C0 (en) 2026-01-28
UY36773A (es) 2017-01-31
SG10202010735PA (en) 2020-11-27
CA2991451A1 (en) 2017-01-12
JP6630426B2 (ja) 2020-01-15
JP2018524001A (ja) 2018-08-30
IL256685A (en) 2018-03-29
JP7100008B2 (ja) 2022-07-12
US20210115121A1 (en) 2021-04-22
HRP20260348T1 (hr) 2026-04-24
CN107849104A (zh) 2018-03-27
CN107849104B (zh) 2021-08-27
AR105267A1 (es) 2017-09-20
JP2022141689A (ja) 2022-09-29
WO2017005734A1 (en) 2017-01-12
KR20250027278A (ko) 2025-02-25
MA42377A (fr) 2018-05-16
EP4729538A2 (en) 2026-04-22
JP7413448B2 (ja) 2024-01-15
KR102770650B1 (ko) 2025-02-19
AU2016289755C1 (en) 2021-08-19
US11732034B2 (en) 2023-08-22
MX2017015817A (es) 2018-04-10

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