HRP20160783T1 - Medij za kultiviranje stanica za ekspresiju adamts proteina - Google Patents

Medij za kultiviranje stanica za ekspresiju adamts proteina Download PDF

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Publication number
HRP20160783T1
HRP20160783T1 HRP20160783TT HRP20160783T HRP20160783T1 HR P20160783 T1 HRP20160783 T1 HR P20160783T1 HR P20160783T T HRP20160783T T HR P20160783TT HR P20160783 T HRP20160783 T HR P20160783T HR P20160783 T1 HRP20160783 T1 HR P20160783T1
Authority
HR
Croatia
Prior art keywords
culture medium
protein
adamts
adamts13
culture
Prior art date
Application number
HRP20160783TT
Other languages
English (en)
Croatian (hr)
Inventor
Leopold Grillberger
Alexandra Spenger
Meinhard Hasslacher
Rana Grillberger
Manfred Reiter
Original Assignee
Baxalta GmbH
Baxalta Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta GmbH, Baxalta Incorporated filed Critical Baxalta GmbH
Publication of HRP20160783T1 publication Critical patent/HRP20160783T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24087—ADAMTS13 endopeptidase (3.4.24.87)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14—Calcium; Ca chelators; Calcitonin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/22—Zinc; Zn chelators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/95—Protein-free medium and culture conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/99—Serum-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
HRP20160783TT 2009-07-31 2010-07-30 Medij za kultiviranje stanica za ekspresiju adamts proteina HRP20160783T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23047709P 2009-07-31 2009-07-31
PCT/US2010/044020 WO2011014838A1 (en) 2009-07-31 2010-07-30 Cell culture medium for adamts protein expression
EP10740810.6A EP2459702B1 (en) 2009-07-31 2010-07-30 Cell culture medium for adamts protein expression

Publications (1)

Publication Number Publication Date
HRP20160783T1 true HRP20160783T1 (hr) 2016-08-12

Family

ID=42668009

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20160783TT HRP20160783T1 (hr) 2009-07-31 2010-07-30 Medij za kultiviranje stanica za ekspresiju adamts proteina

Country Status (21)

Country Link
US (7) US8313926B2 (OSRAM)
EP (1) EP2459702B1 (OSRAM)
JP (5) JP5451884B2 (OSRAM)
KR (5) KR101808496B1 (OSRAM)
CN (2) CN104962539B (OSRAM)
AU (1) AU2010278751B2 (OSRAM)
BR (2) BR122021005965B1 (OSRAM)
CA (1) CA2769361A1 (OSRAM)
CO (1) CO6501191A2 (OSRAM)
EA (1) EA023193B1 (OSRAM)
ES (1) ES2583258T3 (OSRAM)
HR (1) HRP20160783T1 (OSRAM)
HU (1) HUE029110T2 (OSRAM)
IN (1) IN2012DN00801A (OSRAM)
MX (2) MX2012001261A (OSRAM)
NZ (1) NZ597727A (OSRAM)
PL (1) PL2459702T3 (OSRAM)
PT (1) PT2459702T (OSRAM)
SG (1) SG178194A1 (OSRAM)
SI (1) SI2459702T1 (OSRAM)
WO (1) WO2011014838A1 (OSRAM)

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Publication number Publication date
KR101808496B1 (ko) 2017-12-12
US20190071660A1 (en) 2019-03-07
US8313926B2 (en) 2012-11-20
SG178194A1 (en) 2012-03-29
US8759026B2 (en) 2014-06-24
JP2013500724A (ja) 2013-01-10
CN104962539A (zh) 2015-10-07
JP6567707B2 (ja) 2019-08-28
CA2769361A1 (en) 2011-02-03
JP5936232B2 (ja) 2016-06-22
KR101912552B1 (ko) 2018-10-26
US20110086413A1 (en) 2011-04-14
JP7083059B2 (ja) 2022-06-09
CN102549145A (zh) 2012-07-04
BR112012002151B1 (pt) 2021-07-06
KR20150138425A (ko) 2015-12-09
JP2014061005A (ja) 2014-04-10
ES2583258T3 (es) 2016-09-20
JP6511007B2 (ja) 2019-05-08
JP5451884B2 (ja) 2014-03-26
CN104962539B (zh) 2019-09-17
US20170051270A1 (en) 2017-02-23
US10072254B2 (en) 2018-09-11
CO6501191A2 (es) 2012-08-15
NZ597727A (en) 2013-08-30
JP2019201661A (ja) 2019-11-28
KR101573972B1 (ko) 2015-12-02
EP2459702A1 (en) 2012-06-06
JP2018093881A (ja) 2018-06-21
US20140329294A1 (en) 2014-11-06
KR101574056B1 (ko) 2015-12-02
US9441216B2 (en) 2016-09-13
US20130071906A1 (en) 2013-03-21
US20200308566A1 (en) 2020-10-01
CN102549145B (zh) 2015-05-20
EA201270224A1 (ru) 2012-09-28
JP2016144471A (ja) 2016-08-12
AU2010278751B2 (en) 2014-05-15
HUE029110T2 (en) 2017-02-28
WO2011014838A1 (en) 2011-02-03
MX344970B (es) 2017-01-12
JP6883071B2 (ja) 2021-06-09
MX2012001261A (es) 2012-05-22
US20150329848A1 (en) 2015-11-19
PL2459702T3 (pl) 2016-12-30
SI2459702T1 (sl) 2016-11-30
US10724024B2 (en) 2020-07-28
JP2021112210A (ja) 2021-08-05
PT2459702T (pt) 2016-08-02
BR122021005965B1 (pt) 2022-01-25
KR20170140411A (ko) 2017-12-20
EP2459702B1 (en) 2016-05-04
HK1171790A1 (zh) 2013-04-05
IN2012DN00801A (OSRAM) 2015-06-26
EA023193B1 (ru) 2016-05-31
KR20170081747A (ko) 2017-07-12
KR101756354B1 (ko) 2017-07-26
AU2010278751A1 (en) 2012-02-09
KR20150044981A (ko) 2015-04-27
US11254921B2 (en) 2022-02-22
BR112012002151A2 (pt) 2020-03-03
US9127265B2 (en) 2015-09-08
KR20120046301A (ko) 2012-05-09

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