HRP20160249T1 - Pirolidinoni kao inhibitori metap2 - Google Patents

Pirolidinoni kao inhibitori metap2 Download PDF

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HRP20160249T1
HRP20160249T1 HRP20160249TT HRP20160249T HRP20160249T1 HR P20160249 T1 HRP20160249 T1 HR P20160249T1 HR P20160249T T HRP20160249T T HR P20160249TT HR P20160249 T HRP20160249 T HR P20160249T HR P20160249 T1 HRP20160249 T1 HR P20160249T1
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Croatia
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HRP20160249TT
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Timo Heinrich
Frank Zenke
Michel Calderini
Djordje Musil
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Merck Patent Gmbh
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Publication of HRP20160249T1 publication Critical patent/HRP20160249T1/hr

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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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HRP20160249TT 2010-10-13 2011-09-14 Pirolidinoni kao inhibitori metap2 HRP20160249T1 (hr)

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DE102010048374A DE102010048374A1 (de) 2010-10-13 2010-10-13 Pyrrolidinone als MetAP-2 Inhibitoren
EP11761005.5A EP2627631B1 (de) 2010-10-13 2011-09-14 Pyrrolidinone als metap-2 inhibitoren
PCT/EP2011/004608 WO2012048775A1 (de) 2010-10-13 2011-09-14 Pyrrolidinone als metap-2 inhibitoren

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PT2573073E (pt) * 2011-09-26 2015-02-05 Sanofi Sa Derivados de pirazoloquinolinona, sua preparação e sua utilização terapêutica
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WO2017084096A1 (en) * 2015-11-20 2017-05-26 Eli Lilly And Company Pyrrolidinone compounds
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WO2017219083A1 (en) * 2016-06-21 2017-12-28 The University Of Melbourne Activators of hiv latency
WO2018098781A1 (en) * 2016-12-01 2018-06-07 Eli Lilly And Company Pyrrolidinone compounds
US11365194B2 (en) * 2017-09-27 2022-06-21 Kagoshima University Analgesic drug using PAC1 receptor antagonistic drug
CN108409630B (zh) * 2018-02-07 2021-01-15 宁波大学 一种水相中3-羟基-2-吲哚酮衍生物的制备方法
BR112021014220A2 (pt) * 2019-01-22 2022-01-18 Merck Patent Gmbh Derivados heterocíclicos
RS65436B1 (sr) 2019-07-03 2024-05-31 Merck Patent Gmbh Postupak za proizvodnju (s)-3-hidroksi-1-(1h-indol-5-il)-2-okso-pirolidin-3-karboksilne kiseline 3,5-difluoro-benzilamida
CN112480100B (zh) * 2019-09-11 2022-10-14 康威(广州)生物科技有限公司 吡咯烷酮衍生物
CN110759843A (zh) * 2019-09-30 2020-02-07 东北师范大学 一种氟叠氮取代的四元杂环化合物的制备和应用
EP4178572A1 (en) 2020-07-09 2023-05-17 Merck Patent GmbH Combination of a methionine aminopeptidase 2 inhibitor and vegfr/vegf inhibitor
CN112851561A (zh) * 2021-01-29 2021-05-28 南京艾美斐生物医药科技有限公司 一种nr6a1蛋白受体抑制剂及其制备和应用
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CY1117287T1 (el) 2017-04-26
AU2011316199A1 (en) 2013-05-02
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JP2013544781A (ja) 2013-12-19
AR083402A1 (es) 2013-02-21
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AU2011316199B2 (en) 2015-07-23
EP2627631A1 (de) 2013-08-21
EA022299B1 (ru) 2015-12-30
DK2627631T3 (en) 2016-02-01
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US20130296274A1 (en) 2013-11-07
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