SG189853A1 - Pyrrolidinones as metap2 inhibitors - Google Patents

Pyrrolidinones as metap2 inhibitors Download PDF

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Publication number
SG189853A1
SG189853A1 SG2013026133A SG2013026133A SG189853A1 SG 189853 A1 SG189853 A1 SG 189853A1 SG 2013026133 A SG2013026133 A SG 2013026133A SG 2013026133 A SG2013026133 A SG 2013026133A SG 189853 A1 SG189853 A1 SG 189853A1
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Singapore
Prior art keywords
hydroxy
carboxylic acid
amide
oxo
chloro
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Application number
SG2013026133A
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English (en)
Inventor
Timo Heinrich
Frank Zenke
Michel Calderini
Djordje Musil
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Merck Patent Gmbh
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Publication date
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Publication of SG189853A1 publication Critical patent/SG189853A1/en

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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CN110759843A (zh) * 2019-09-30 2020-02-07 东北师范大学 一种氟叠氮取代的四元杂环化合物的制备和应用
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