HRP20160168T1 - Kristalne forme makrolida i njihova uporaba - Google Patents

Kristalne forme makrolida i njihova uporaba Download PDF

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Publication number
HRP20160168T1
HRP20160168T1 HRP20160168T HRP20160168T HRP20160168T1 HR P20160168 T1 HRP20160168 T1 HR P20160168T1 HR P20160168 T HRP20160168 T HR P20160168T HR P20160168 T HRP20160168 T HR P20160168T HR P20160168 T1 HRP20160168 T1 HR P20160168T1
Authority
HR
Croatia
Prior art keywords
cem
solution
water
peaks
radiation
Prior art date
Application number
HRP20160168T
Other languages
English (en)
Croatian (hr)
Inventor
David E Pereira
Original Assignee
Cempra Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44673574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20160168(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cempra Pharmaceuticals Inc filed Critical Cempra Pharmaceuticals Inc
Publication of HRP20160168T1 publication Critical patent/HRP20160168T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HRP20160168T 2010-03-22 2011-03-22 Kristalne forme makrolida i njihova uporaba HRP20160168T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31606310P 2010-03-22 2010-03-22
PCT/US2011/029424 WO2011119604A1 (en) 2010-03-22 2011-03-22 Crystalline forms of a macrolide, and uses therefor
EP11760068.4A EP2550286B1 (en) 2010-03-22 2011-03-22 Crystalline forms of a macrolide, and uses therefor

Publications (1)

Publication Number Publication Date
HRP20160168T1 true HRP20160168T1 (hr) 2016-03-25

Family

ID=44673574

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20160168T HRP20160168T1 (hr) 2010-03-22 2011-03-22 Kristalne forme makrolida i njihova uporaba

Country Status (19)

Country Link
US (4) US8975386B2 (https=)
EP (2) EP3009442B1 (https=)
JP (4) JP5711352B2 (https=)
KR (2) KR20180101643A (https=)
CN (2) CN108570083A (https=)
AU (2) AU2011232627B2 (https=)
BR (1) BR112012023950A2 (https=)
CA (1) CA2793884C (https=)
DK (1) DK2550286T3 (https=)
ES (1) ES2564097T3 (https=)
HR (1) HRP20160168T1 (https=)
IL (1) IL222018B (https=)
MX (1) MX361413B (https=)
MY (1) MY162411A (https=)
NZ (1) NZ602544A (https=)
PL (1) PL2550286T3 (https=)
RU (1) RU2650883C2 (https=)
SI (1) SI2550286T1 (https=)
WO (1) WO2011119604A1 (https=)

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US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
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CN105198944B (zh) 2010-05-20 2018-06-01 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
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KR20170039689A (ko) * 2014-08-05 2017-04-11 셈프라 파마슈티컬스, 인크. 항균제의 분말 경구 현탁제 제형
CN104151382B (zh) * 2014-08-08 2016-09-14 广东东阳光药业有限公司 一种固态大环内酯的晶型
CN104311611B (zh) * 2014-08-13 2017-01-18 广东东阳光药业有限公司 一种制备固态大环内酯的方法
US10633407B2 (en) 2014-10-08 2020-04-28 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
JP2018509452A (ja) 2015-03-25 2018-04-05 プレジデント アンド フェローズ オブ ハーバード カレッジ 修飾デソサミン糖をもつマクロライドおよびその使用
JP6112696B1 (ja) * 2015-10-05 2017-04-12 富山化学工業株式会社 ソリスロマイシンを含む錠剤
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Also Published As

Publication number Publication date
RU2650883C2 (ru) 2018-04-18
US8759500B2 (en) 2014-06-24
CA2793884A1 (en) 2011-09-29
CA2793884C (en) 2019-09-10
AU2016203986A1 (en) 2016-06-30
PL2550286T3 (pl) 2016-07-29
AU2011232627A1 (en) 2012-10-18
JP2017081953A (ja) 2017-05-18
JP6121387B2 (ja) 2017-04-26
KR20180101643A (ko) 2018-09-12
JP2015063536A (ja) 2015-04-09
EP3009442A1 (en) 2016-04-20
EP2550286A4 (en) 2013-10-02
KR20130056226A (ko) 2013-05-29
EP3009442B1 (en) 2019-06-19
MX2012010895A (es) 2013-02-15
AU2016203986B2 (en) 2016-10-06
MX361413B (es) 2018-12-05
US8975386B2 (en) 2015-03-10
BR112012023950A2 (pt) 2016-07-05
JP5711352B2 (ja) 2015-04-30
JP2013522367A (ja) 2013-06-13
HK1177937A1 (en) 2013-08-30
IL222018B (en) 2019-05-30
EP2550286B1 (en) 2015-12-09
SI2550286T1 (sl) 2016-04-29
NZ602544A (en) 2014-11-28
AU2011232627B2 (en) 2016-03-17
CN108570083A (zh) 2018-09-25
JP2020002168A (ja) 2020-01-09
US20190040096A1 (en) 2019-02-07
US20130252915A1 (en) 2013-09-26
KR102006200B1 (ko) 2019-08-01
WO2011119604A1 (en) 2011-09-29
MY162411A (en) 2017-06-15
DK2550286T3 (en) 2016-02-29
US20130018008A1 (en) 2013-01-17
RU2012144614A (ru) 2014-04-27
US20160244472A1 (en) 2016-08-25
CN103080122A (zh) 2013-05-01
EP2550286A1 (en) 2013-01-30
ES2564097T3 (es) 2016-03-17

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