HRP20130128T1 - Supstituirani aromatski derivati karboksamida i ureje kao ligandi vaniloidnog receptora - Google Patents

Supstituirani aromatski derivati karboksamida i ureje kao ligandi vaniloidnog receptora Download PDF

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Publication number
HRP20130128T1
HRP20130128T1 HRP20130128AT HRP20130128T HRP20130128T1 HR P20130128 T1 HRP20130128 T1 HR P20130128T1 HR P20130128A T HRP20130128A T HR P20130128AT HR P20130128 T HRP20130128 T HR P20130128T HR P20130128 T1 HRP20130128 T1 HR P20130128T1
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HR
Croatia
Prior art keywords
methyl
alkyl
pyrazol
trifluoromethyl
chlorophenyl
Prior art date
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HRP20130128AT
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English (en)
Croatian (hr)
Inventor
Robert Frank
Gregor Bahrenberg
Thomas Christoph
Klaus Schiene
Jean De Vry
Nils Damann
Sven Frormann
Bernhard Lesch
Jeewoo Lee
Yong-Soo Kim
Myeong-Seop Kim
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Grünenthal GmbH
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Publication of HRP20130128T1 publication Critical patent/HRP20130128T1/hr

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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
HRP20130128AT 2009-05-07 2010-05-06 Supstituirani aromatski derivati karboksamida i ureje kao ligandi vaniloidnog receptora HRP20130128T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17627709P 2009-05-07 2009-05-07
EP09006221 2009-05-07
PCT/EP2010/002785 WO2010127855A1 (en) 2009-05-07 2010-05-06 Substituted aromatic carboxamide and urea derivatives as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
HRP20130128T1 true HRP20130128T1 (hr) 2013-03-31

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ID=40848721

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20130128AT HRP20130128T1 (hr) 2009-05-07 2010-05-06 Supstituirani aromatski derivati karboksamida i ureje kao ligandi vaniloidnog receptora

Country Status (16)

Country Link
US (1) US8334315B2 (https=)
EP (1) EP2427436B1 (https=)
JP (1) JP5767631B2 (https=)
AR (1) AR076753A1 (https=)
AU (1) AU2010244684B2 (https=)
BR (1) BRPI1011192A2 (https=)
CA (1) CA2758289A1 (https=)
DK (1) DK2427436T3 (https=)
ES (1) ES2402805T3 (https=)
HR (1) HRP20130128T1 (https=)
MX (1) MX2011011800A (https=)
PL (1) PL2427436T3 (https=)
PT (1) PT2427436E (https=)
SI (1) SI2427436T1 (https=)
TW (1) TWI504589B (https=)
WO (1) WO2010127855A1 (https=)

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BR112014001714A2 (pt) 2011-07-26 2017-02-14 Gruenenthal Gmbh derivados de carboxamida e ureia aromáticos bicíclicos substituídos como ligantes de receptor vaniloide
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WO2013068467A1 (en) 2011-11-09 2013-05-16 Grünenthal GmbH Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with a co-containing group as vanilloid receptor ligands
AR088702A1 (es) 2011-11-09 2014-06-25 Gruenenthal Gmbh Derivados de carboxamida y urea, basados en pirazolilo sustituido, que presentan una porcion fenilo sustituida con un grupo que contiene o como ligando de receptor vainilloide
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HK1214252A1 (zh) 2013-03-15 2016-07-22 Verseon Corporation 作為凝血酶抑制劑的鹵代吡唑
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