PL4019485T3 - Sposób wytwarzania pochodnych heterocyklidenoacetamidu - Google Patents
Sposób wytwarzania pochodnych heterocyklidenoacetamiduInfo
- Publication number
- PL4019485T3 PL4019485T3 PL20859098.4T PL20859098T PL4019485T3 PL 4019485 T3 PL4019485 T3 PL 4019485T3 PL 20859098 T PL20859098 T PL 20859098T PL 4019485 T3 PL4019485 T3 PL 4019485T3
- Authority
- PL
- Poland
- Prior art keywords
- producing
- acetamide derivatives
- heterocyclidene
- heterocyclidene acetamide
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
- C07C209/10—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/68—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/70—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/30—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/48—Halogenated derivatives
- C07C35/52—Alcohols with a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B61/00—Other general methods
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910783254.8A CN112409191A (zh) | 2019-08-23 | 2019-08-23 | 光学活性的氨基醇的制备方法 |
| PCT/JP2019/036451 WO2021038889A1 (ja) | 2019-08-23 | 2019-09-18 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
| CN202010355546.4A CN113563209A (zh) | 2020-04-29 | 2020-04-29 | 光学活性的氨基醇的制备方法 |
| PCT/JP2020/022827 WO2021039023A1 (ja) | 2019-08-23 | 2020-06-10 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4019485T3 true PL4019485T3 (pl) | 2024-10-21 |
Family
ID=74562354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20859098.4T PL4019485T3 (pl) | 2019-08-23 | 2020-06-10 | Sposób wytwarzania pochodnych heterocyklidenoacetamidu |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12286414B2 (pl) |
| EP (1) | EP4410989A3 (pl) |
| JP (1) | JP6830569B1 (pl) |
| KR (2) | KR102886188B1 (pl) |
| CN (2) | CN118812481A (pl) |
| AU (2) | AU2020335426B2 (pl) |
| CA (1) | CA3150748A1 (pl) |
| ES (1) | ES2987016T3 (pl) |
| MX (2) | MX2022002017A (pl) |
| PL (1) | PL4019485T3 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021039023A1 (ja) * | 2019-08-23 | 2021-03-04 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
| HUE068289T2 (hu) * | 2019-08-23 | 2024-12-28 | Mochida Pharm Co Ltd | Eljárás heterociklidén-acetamid származékok elõállítására |
| CN118812481A (zh) | 2019-08-23 | 2024-10-22 | 持田制药株式会社 | 杂环亚基乙酰胺衍生物的制造方法 |
| KR20250065723A (ko) | 2022-09-29 | 2025-05-13 | 센주 세이야꾸 가부시키가이샤 | 멸균 처리한 헤테로시클리덴아세트아미드 유도체 함유 현탁액 |
| JP7589394B2 (ja) | 2022-09-29 | 2024-11-25 | 千寿製薬株式会社 | ヘテロシクリデンアセトアミド誘導体を含む配合剤 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1335591C (en) | 1988-05-23 | 1995-05-16 | James Arthur Nixon | Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes |
| EP0381902A1 (en) | 1989-01-09 | 1990-08-16 | Merrell Dow Pharmaceuticals Inc. | Tetralin derivatives |
| US5136103A (en) | 1991-09-30 | 1992-08-04 | Shell Oil Company | Process for the preparation of ketones |
| US5225339A (en) | 1992-02-26 | 1993-07-06 | The Scripps Research Institute | Lactobacillus kefir alcohol dehydrogenase |
| US5593992A (en) | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
| US6137002A (en) | 1993-07-22 | 2000-10-24 | Eli Lilly And Company | Glycoprotein IIb/IIIa antagonists |
| WO2002059107A1 (en) * | 2001-01-23 | 2002-08-01 | Eli Lilly And Company | Substituted piperidines/piperazines as melanocortin receptor agonists |
| BR0309940A (pt) | 2002-05-08 | 2005-02-09 | Bayer Healthcare Ag | Derivados de hidróxi-tetraidro-naftaleniluréia |
| US7056540B2 (en) | 2002-10-29 | 2006-06-06 | Council Of Scientific And Industrial Research | Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root Daucus carota |
| JP4833069B2 (ja) | 2003-10-01 | 2011-12-07 | ゼンション・リミテッド | テトラヒドロ−ナフタレンおよび尿素誘導体 |
| WO2005040100A1 (en) | 2003-10-15 | 2005-05-06 | Bayer Healthcare Ag | Tetrahydro-naphthalene and urea derivatives |
| JP4754566B2 (ja) * | 2005-07-22 | 2011-08-24 | 持田製薬株式会社 | 新規なヘテロシクリデンアセトアミド誘導体 |
| CN101228131B (zh) * | 2005-07-22 | 2013-01-09 | 持田制药株式会社 | 新的杂环亚基乙酰胺衍生物 |
| US7750135B2 (en) | 2006-07-28 | 2010-07-06 | Board Of Trustees Of Michigan State University | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols |
| US20100016285A1 (en) | 2007-01-24 | 2010-01-21 | Mochida Pharmaceutical Co., Ltd. | Heterocyclidene-n-(aryl) acetamide derivative |
| PE20081692A1 (es) * | 2007-01-24 | 2008-12-18 | Mochida Pharm Co Ltd | Nuevo derivado de heterocicliden acetamida |
| AU2008313620A1 (en) | 2007-10-19 | 2009-04-23 | Abbott Gmbh & Co. Kg | Solid dispersion product containing N-aryl urea-based compound |
| US7998993B2 (en) | 2007-10-25 | 2011-08-16 | Abbott Laboratories | TRPV1 antagonists |
| JP2011201777A (ja) * | 2008-07-23 | 2011-10-13 | Mochida Pharmaceut Co Ltd | 光学活性なヘテロシクリデン−n−アリールアセトアミド誘導体 |
| JP2012006837A (ja) | 2008-09-30 | 2012-01-12 | Mochida Pharmaceut Co Ltd | 2−インドールアクリルアミド類縁体 |
| US8609692B2 (en) | 2008-10-17 | 2013-12-17 | Abbvie Inc. | TRPV1 antagonists |
| CN102186836A (zh) | 2008-10-17 | 2011-09-14 | 雅培制药有限公司 | Trpv1拮抗剂 |
| BRPI1011192A2 (pt) | 2009-05-07 | 2016-03-15 | Gruenenthal Gmbh | derivados de carboxamida e ureia aromáticas substituídas como ligantes de receptor de vaniloide, composição farmacêutica, uso e processo para preparação dos referidos derivados |
| CN107880058A (zh) * | 2016-09-30 | 2018-04-06 | 江苏三月光电科技有限公司 | 一种含有苯并杂环的化合物及其在oled器件上的应用 |
| WO2018205948A1 (en) | 2017-05-11 | 2018-11-15 | Glaxosmithkline Intellectual Property Development Limited | Compounds |
| CN109956872A (zh) * | 2017-12-22 | 2019-07-02 | 苏州鹏旭医药科技有限公司 | 一种4-环丙基-1-萘胺的制备方法 |
| CN108276380A (zh) * | 2018-03-29 | 2018-07-13 | 辅仁药业集团熙德隆肿瘤药品有限公司 | 一种泊马度胺的合成方法 |
| CN118812481A (zh) | 2019-08-23 | 2024-10-22 | 持田制药株式会社 | 杂环亚基乙酰胺衍生物的制造方法 |
| WO2021039023A1 (ja) | 2019-08-23 | 2021-03-04 | 持田製薬株式会社 | ヘテロシクリデンアセトアミド誘導体の製造方法 |
-
2020
- 2020-06-10 CN CN202410793215.7A patent/CN118812481A/zh active Pending
- 2020-06-10 ES ES20859098T patent/ES2987016T3/es active Active
- 2020-06-10 CN CN202080058490.4A patent/CN114206847B/zh active Active
- 2020-06-10 KR KR1020227004193A patent/KR102886188B1/ko active Active
- 2020-06-10 JP JP2020557359A patent/JP6830569B1/ja active Active
- 2020-06-10 CA CA3150748A patent/CA3150748A1/en active Pending
- 2020-06-10 EP EP24184274.9A patent/EP4410989A3/en active Pending
- 2020-06-10 PL PL20859098.4T patent/PL4019485T3/pl unknown
- 2020-06-10 AU AU2020335426A patent/AU2020335426B2/en active Active
- 2020-06-10 MX MX2022002017A patent/MX2022002017A/es unknown
- 2020-06-10 KR KR1020257037576A patent/KR20250166332A/ko active Pending
-
2021
- 2021-09-27 US US17/486,265 patent/US12286414B2/en active Active
-
2022
- 2022-02-16 MX MX2025003091A patent/MX2025003091A/es unknown
-
2025
- 2025-03-24 US US19/088,091 patent/US20250250246A1/en active Pending
- 2025-09-24 AU AU2025237949A patent/AU2025237949A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2020335426B2 (en) | 2025-08-14 |
| KR102886188B1 (ko) | 2025-11-14 |
| EP4410989A2 (en) | 2024-08-07 |
| US20220009898A1 (en) | 2022-01-13 |
| JPWO2021039023A1 (ja) | 2021-09-13 |
| ES2987016T3 (es) | 2024-11-13 |
| KR20220051168A (ko) | 2022-04-26 |
| AU2020335426A1 (en) | 2022-03-10 |
| CA3150748A1 (en) | 2021-03-04 |
| MX2025003091A (es) | 2025-04-02 |
| CN114206847A (zh) | 2022-03-18 |
| US20250250246A1 (en) | 2025-08-07 |
| AU2025237949A1 (en) | 2025-10-16 |
| KR20250166332A (ko) | 2025-11-27 |
| EP4410989A3 (en) | 2024-12-11 |
| CN118812481A (zh) | 2024-10-22 |
| US12286414B2 (en) | 2025-04-29 |
| MX2022002017A (es) | 2022-03-11 |
| CN114206847B (zh) | 2024-07-16 |
| JP6830569B1 (ja) | 2021-02-17 |
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