HRP20120957T1 - Stabilni farmaceutski sastav koji sadrži pirimidin-sulfamid - Google Patents

Stabilni farmaceutski sastav koji sadrži pirimidin-sulfamid Download PDF

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Publication number
HRP20120957T1
HRP20120957T1 HRP20120957TT HRP20120957T HRP20120957T1 HR P20120957 T1 HRP20120957 T1 HR P20120957T1 HR P20120957T T HRP20120957T T HR P20120957TT HR P20120957 T HRP20120957 T HR P20120957T HR P20120957 T1 HRP20120957 T1 HR P20120957T1
Authority
HR
Croatia
Prior art keywords
pharmaceutical composition
pirimidine
sulfamide
composition containing
stable pharmaceutical
Prior art date
Application number
HRP20120957TT
Other languages
English (en)
Croatian (hr)
Inventor
Charles Tokunbo Adesuyi
Lovelace Holman
Olivier Lambert
Bruce Hamilton Lithgow
Original Assignee
Actelion Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37865339&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20120957(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Actelion Pharmaceuticals Ltd. filed Critical Actelion Pharmaceuticals Ltd.
Publication of HRP20120957T1 publication Critical patent/HRP20120957T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HRP20120957TT 2005-09-12 2006-09-11 Stabilni farmaceutski sastav koji sadrži pirimidin-sulfamid HRP20120957T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2005009775 2005-09-12
PCT/IB2006/053210 WO2007031933A2 (en) 2005-09-12 2006-09-11 Stable pharmaceutical composition comprising a pyrimidine-sulfamide

Publications (1)

Publication Number Publication Date
HRP20120957T1 true HRP20120957T1 (hr) 2012-12-31

Family

ID=37865339

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20120957TT HRP20120957T1 (hr) 2005-09-12 2006-09-11 Stabilni farmaceutski sastav koji sadrži pirimidin-sulfamid

Country Status (23)

Country Link
US (6) US20080233188A1 (enExample)
EP (2) EP1928409B1 (enExample)
JP (2) JP4955685B2 (enExample)
KR (1) KR101313395B1 (enExample)
CN (1) CN101262847B (enExample)
AU (1) AU2006290309B2 (enExample)
BR (1) BRPI0615898B8 (enExample)
CA (1) CA2621273C (enExample)
CY (1) CY1113395T1 (enExample)
DK (1) DK1928409T3 (enExample)
ES (1) ES2393117T3 (enExample)
HR (1) HRP20120957T1 (enExample)
IL (1) IL190072A (enExample)
MY (1) MY151003A (enExample)
NO (1) NO341325B1 (enExample)
NZ (1) NZ567188A (enExample)
PL (1) PL1928409T3 (enExample)
PT (1) PT1928409E (enExample)
RU (1) RU2424805C2 (enExample)
SI (1) SI1928409T1 (enExample)
TW (1) TWI323661B (enExample)
WO (1) WO2007031933A2 (enExample)
ZA (1) ZA200802947B (enExample)

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TW202042818A (zh) * 2019-01-25 2020-12-01 瑞士商艾克泰聯製藥有限公司 用於治療慢性血栓性肺高血壓之醫藥組成物
JP2022533237A (ja) 2019-05-22 2022-07-21 シージャーヂュアン・サガシティー・ニュー・ドラッグ・デヴェロップメント・カンパニー・リミテッド ピリミジンスルホンアミド系化合物の結晶形及びその製造方法
US20220249381A1 (en) 2019-07-05 2022-08-11 TECNIMEDE - Sociedade Técnico-medicinal, SA Compressed macitentan compositions, methods and uses thereof
ES2994089T3 (en) 2019-11-29 2025-01-17 Actelion Pharmaceuticals Ltd Initial triple combination therapy with macitentan, tadalafil, and selexipag for treating pulmonary arterial hypertension
WO2022238375A1 (en) 2021-05-11 2022-11-17 Actelion Pharmaceuticals Ltd Methods of treating pulmonary hypertension
TW202317119A (zh) * 2021-06-11 2023-05-01 瑞士商艾克泰聯製藥有限公司 用於口服投予之分散錠
JP2024530727A (ja) 2021-08-25 2024-08-23 ビーエーエスエフ ソシエタス・ヨーロピア 直接打錠補助組成物
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Also Published As

Publication number Publication date
CN101262847B (zh) 2010-11-24
KR20080055897A (ko) 2008-06-19
US20100004274A1 (en) 2010-01-07
NZ567188A (en) 2011-04-29
US20210186966A1 (en) 2021-06-24
US10117870B2 (en) 2018-11-06
US20180263980A1 (en) 2018-09-20
KR101313395B1 (ko) 2013-10-02
TW200803860A (en) 2008-01-16
DK1928409T3 (da) 2012-11-05
WO2007031933A2 (en) 2007-03-22
EP2292209A3 (en) 2011-05-04
IL190072A (en) 2013-08-29
JP5054061B2 (ja) 2012-10-24
IL190072A0 (en) 2008-08-07
BRPI0615898B8 (pt) 2021-05-25
NO341325B1 (no) 2017-10-16
EP1928409A2 (en) 2008-06-11
WO2007031933A3 (en) 2007-10-18
PL1928409T3 (pl) 2013-02-28
US20130190336A1 (en) 2013-07-25
US10946015B2 (en) 2021-03-16
RU2424805C2 (ru) 2011-07-27
CN101262847A (zh) 2008-09-10
US20160136163A1 (en) 2016-05-19
US8367685B2 (en) 2013-02-05
MY151003A (en) 2014-03-31
EP1928409B1 (en) 2012-09-12
RU2008113869A (ru) 2009-10-20
CA2621273C (en) 2014-07-29
BRPI0615898A2 (pt) 2011-05-31
ZA200802947B (en) 2009-12-30
US20080233188A1 (en) 2008-09-25
JP2009235073A (ja) 2009-10-15
SI1928409T1 (sl) 2012-12-31
NO20081724L (no) 2008-04-09
US11648249B2 (en) 2023-05-16
HK1121950A1 (en) 2009-05-08
EP2292209A2 (en) 2011-03-09
AU2006290309B2 (en) 2012-04-05
JP2009519893A (ja) 2009-05-21
CY1113395T1 (el) 2016-06-22
US9265762B2 (en) 2016-02-23
CA2621273A1 (en) 2007-03-22
PT1928409E (pt) 2012-11-27
BRPI0615898B1 (pt) 2020-02-18
AU2006290309A1 (en) 2007-03-22
JP4955685B2 (ja) 2012-06-20
ES2393117T3 (es) 2012-12-18
TWI323661B (en) 2010-04-21

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