CY1113395T1 - Σταθερη φαρμακευτικη συνθεση που περιεχει πυριμιδινη-σουλφαμιδη - Google Patents
Σταθερη φαρμακευτικη συνθεση που περιεχει πυριμιδινη-σουλφαμιδηInfo
- Publication number
- CY1113395T1 CY1113395T1 CY20121101126T CY121101126T CY1113395T1 CY 1113395 T1 CY1113395 T1 CY 1113395T1 CY 20121101126 T CY20121101126 T CY 20121101126T CY 121101126 T CY121101126 T CY 121101126T CY 1113395 T1 CY1113395 T1 CY 1113395T1
- Authority
- CY
- Cyprus
- Prior art keywords
- sulfamidi
- pharmaceutical composition
- composition containing
- stable pharmaceutical
- containing pyrimidine
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000000877 morphologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2005009775 | 2005-09-12 | ||
| EP06809280A EP1928409B1 (en) | 2005-09-12 | 2006-09-11 | Stable pharmaceutical composition comprising a pyrimidine-sulfamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1113395T1 true CY1113395T1 (el) | 2016-06-22 |
Family
ID=37865339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121101126T CY1113395T1 (el) | 2005-09-12 | 2012-11-21 | Σταθερη φαρμακευτικη συνθεση που περιεχει πυριμιδινη-σουλφαμιδη |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US20080233188A1 (enExample) |
| EP (2) | EP1928409B1 (enExample) |
| JP (2) | JP4955685B2 (enExample) |
| KR (1) | KR101313395B1 (enExample) |
| CN (1) | CN101262847B (enExample) |
| AU (1) | AU2006290309B2 (enExample) |
| BR (1) | BRPI0615898B8 (enExample) |
| CA (1) | CA2621273C (enExample) |
| CY (1) | CY1113395T1 (enExample) |
| DK (1) | DK1928409T3 (enExample) |
| ES (1) | ES2393117T3 (enExample) |
| HR (1) | HRP20120957T1 (enExample) |
| IL (1) | IL190072A (enExample) |
| MY (1) | MY151003A (enExample) |
| NO (1) | NO341325B1 (enExample) |
| NZ (1) | NZ567188A (enExample) |
| PL (1) | PL1928409T3 (enExample) |
| PT (1) | PT1928409E (enExample) |
| RU (1) | RU2424805C2 (enExample) |
| SI (1) | SI1928409T1 (enExample) |
| TW (1) | TWI323661B (enExample) |
| WO (1) | WO2007031933A2 (enExample) |
| ZA (1) | ZA200802947B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101313395B1 (ko) | 2005-09-12 | 2013-10-02 | 액테리온 파마슈티칼 리미티드 | 피리미딘-설파마이드를 함유하는 안정한 제약학적 조성물 |
| AR062501A1 (es) * | 2006-08-29 | 2008-11-12 | Actelion Pharmaceuticals Ltd | Composiciones terapeuticas |
| TWI399223B (zh) * | 2006-09-15 | 2013-06-21 | Daiichi Sankyo Co Ltd | 奧美沙坦酯及氨氯地平之固體劑型 |
| MX2010001837A (es) * | 2007-08-17 | 2010-03-10 | Actelion Pharmaceuticals Ltd | Derivados de 4-pirimidinasulfamida. |
| KR20100132489A (ko) * | 2008-02-20 | 2010-12-17 | 액테리온 파마슈티칼 리미티드 | 난소암을 치료하기 위하여 파클리탁셀을 포함하는 조합 |
| HUE047767T2 (hu) * | 2008-08-13 | 2020-05-28 | Actelion Pharmaceuticals Ltd | Macitentánt tartalmazó terápiás készítmények |
| ES2543280T3 (es) * | 2009-08-10 | 2015-08-17 | Board Of Regents, The University Of Texas System | Tratamiento de metástasis cerebrales con inhibidores de los receptores de endotelina en combinación con un agente quimioterapéutico citotóxico |
| US10071059B2 (en) | 2009-12-18 | 2018-09-11 | Frieslandcampina Nederland Holding B.V. | Co-processed tablet excipient composition its preparation and use |
| IT1403248B1 (it) * | 2010-11-12 | 2013-10-17 | Scharper Therapeutics Srl | Composizione per il trattamento di disfunzioni degli apparati fonatorio ed olfattorio |
| TW201309298A (zh) | 2011-02-04 | 2013-03-01 | Actelion Pharmaceuticals Ltd | 治療惡性神經膠質瘤之醫藥組合物 |
| DE14721256T1 (de) * | 2013-04-22 | 2017-03-16 | Sandoz Ag | Pharmazeutische zusammensetzungen mit kristallinem macitentan |
| NZ714963A (en) | 2013-06-13 | 2020-07-31 | Akebia Therapeutics Inc | Compositions and methods for treating anemia |
| WO2014198178A1 (zh) * | 2013-06-14 | 2014-12-18 | 杭州普晒医药科技有限公司 | 马西替坦晶体及其制备方法、其药物组合物和用途 |
| US20170158645A1 (en) * | 2014-07-15 | 2017-06-08 | Olon S.P.A. | Amorphous form and new crystalline forms of macitentan |
| DK3172209T3 (da) | 2014-07-25 | 2021-02-22 | Novartis Ag | Tabletformulering med 2-fluor-n-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamid |
| CN105388244B (zh) * | 2015-12-10 | 2017-03-08 | 合肥久诺医药科技有限公司 | 一种马西替坦有关物质的高效液相色谱分析方法 |
| WO2018153925A1 (en) | 2017-02-22 | 2018-08-30 | Amneal Pharmaceuticals Company Gmbh | Stable pharmaceutical compositions comprising macitentan |
| SI3897646T1 (sl) | 2018-12-21 | 2024-08-30 | ACTELION PHARMACEUTICALS lTD, | Makitentan za zdravljenje pljučne arterijske hipertenzije |
| TW202042818A (zh) | 2019-01-25 | 2020-12-01 | 瑞士商艾克泰聯製藥有限公司 | 用於治療慢性血栓性肺高血壓之醫藥組成物 |
| RS66002B1 (sr) | 2019-05-22 | 2024-10-31 | Wuxi Biocity Biopharmaceutics Co Ltd | Kristalni oblik jedinjenja pirimidin sulfonamida i postupak za njegovu pripremu |
| AU2020309223B2 (en) | 2019-07-05 | 2025-05-29 | TECNIMEDE - Sociedade Técnico-Medicinal, S.A | Compressed macitentan compositions, methods and uses thereof |
| TW202133851A (zh) | 2019-11-29 | 2021-09-16 | 瑞士商艾克泰聯製藥有限公司 | 治療肺動脈高血壓之方法 |
| WO2022238375A1 (en) | 2021-05-11 | 2022-11-17 | Actelion Pharmaceuticals Ltd | Methods of treating pulmonary hypertension |
| TW202317119A (zh) * | 2021-06-11 | 2023-05-01 | 瑞士商艾克泰聯製藥有限公司 | 用於口服投予之分散錠 |
| CN117835971A (zh) | 2021-08-25 | 2024-04-05 | 巴斯夫欧洲公司 | 直接压片用辅料组合物 |
| WO2023038600A1 (en) * | 2021-09-07 | 2023-03-16 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | A capsule formulation comprising macitentan |
| EP4154873A1 (en) | 2021-09-22 | 2023-03-29 | Sanovel Ilac Sanayi Ve Ticaret A.S. | The tablet comprising macitentan |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945098A (en) | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
| JPH04103525A (ja) | 1990-08-22 | 1992-04-06 | Sanwa Kagaku Kenkyusho Co Ltd | 難水溶性薬物の持続性製剤化方法 |
| RU2086544C1 (ru) * | 1991-06-13 | 1997-08-10 | Хоффманн-Ля Рош АГ | Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина |
| CA2124690C (en) | 1992-10-02 | 2007-09-11 | Thomas Osterberg | Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer |
| US5811120A (en) | 1994-03-02 | 1998-09-22 | Eli Lilly And Company | Solid orally administerable raloxifene hydrochloride pharmaceutical formulation |
| TW442301B (en) | 1995-06-07 | 2001-06-23 | Sanofi Synthelabo | Pharmaceutical compositions containing irbesartan |
| ATE201202T1 (de) | 1995-12-20 | 2001-06-15 | Yamanouchi Pharma Co Ltd | Arylethensulfonamid-derivate und diese enthaltende medikamente |
| JPH103525A (ja) | 1996-06-14 | 1998-01-06 | Dainippon Printing Co Ltd | Ｉｃカード、命令コード格納方法及び命令コード実行方法 |
| AR017426A1 (es) | 1997-12-08 | 2001-09-05 | Smithkline Beecham Corp | Sal de monoargininilo del acido (e)-3-[1-n-butil-5-[2-(2-carboxifenil)metoxi-4-clorofenil]-1h-pirazol-4-il]-2-[(5-metoxi-2,3-dihidrobenzofuran-6-il)metil]-prop-2-enoico, composicion farmaceutica que la contiene, su uso para la manufactura de un medicamento y procedimiento para su preparacion |
| ATE219658T1 (de) | 1998-03-06 | 2002-07-15 | Eurand Int | Schnell zerfallende tablette |
| US20010014352A1 (en) * | 1998-05-27 | 2001-08-16 | Udit Batra | Compressed tablet formulation |
| US20040062803A1 (en) * | 1999-12-22 | 2004-04-01 | Hedden David B. | Sustained-release formulation of a cyclooxygenase-2 inhibitor |
| CZ20022293A3 (cs) * | 1999-12-31 | 2003-04-16 | Texas Biotechnology Corporation | Sulfonamidy a jejich deriváty, které upravují aktivitu endothelinu |
| GB0001621D0 (en) | 2000-01-26 | 2000-03-15 | Astrazeneca Ab | Pharmaceutical compositions |
| JP2001335469A (ja) | 2000-05-26 | 2001-12-04 | Lion Corp | 固体製剤の製造方法 |
| HUP0301802A3 (en) | 2000-06-28 | 2009-04-28 | Teva Pharma | Process for producing carvedilol, crystalline carvedilol, process for producing it and pharmaceutical composition containing it |
| US7125565B2 (en) | 2000-12-01 | 2006-10-24 | Kyowa Hakko Kogyo Co., Ltd. | Composition improved in the solubility or oral absorbability |
| CN1486302A (zh) | 2000-12-07 | 2004-03-31 | CV���ƹ�˾ | 作为抗冠状动脉疾病或动脉硬化的abca-1加强化合物的取代1,3,5-三嗪和嘧啶 |
| KR100819668B1 (ko) * | 2000-12-18 | 2008-04-04 | 액테리온 파마슈티칼 리미티드 | 신규한 피리미딘-설퍼아마이드 |
| FR2819720B1 (fr) * | 2001-01-22 | 2004-03-12 | Fournier Lab Sa | Nouveaux comprimes de fenofibrate |
| JP3930290B2 (ja) | 2001-09-12 | 2007-06-13 | 富士フイルム株式会社 | 熱現像感光材料及びそれを用いた熱現像方法 |
| KR20030041577A (ko) * | 2001-11-20 | 2003-05-27 | 디디에스텍주식회사 | 난용성 약물과 치환된 시클로덱스트린을 함유하는고체분산체 및 이를 함유하는 약제학적 조성물 |
| JP2006502083A (ja) * | 2002-01-07 | 2006-01-19 | ファルマシア コーポレイション | 高められた溶解速度を有する薬物混合物 |
| MXPA04007737A (es) | 2002-02-11 | 2004-10-15 | Pfizer | Derivados de nicotinamida utiles como inhibidores de fosfodesterasas 4. |
| IL163642A0 (en) * | 2002-02-26 | 2005-12-18 | Astrazeneca Ab | Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative |
| GB0204771D0 (en) | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
| WO2004067008A1 (ja) | 2003-01-28 | 2004-08-12 | Takeda Pharmaceutical Company Limited | 受容体作動薬 |
| MXPA05009098A (es) | 2003-02-25 | 2005-11-17 | Lilly Co Eli | Clorhidrato de 1- (4-(2 -piperidiniletoxifenoxi) -2-(4-metansulfonilfenil) -6-hidroxinaftaleno cristalino no solvatado. |
| EP1697382A4 (en) | 2003-12-10 | 2008-11-05 | Activbiotics Inc | ANALOGUES OF RIFAMYCIN AND USES THEREOF |
| US7094081B1 (en) * | 2005-03-24 | 2006-08-22 | Delphi Technologies, Inc. | Electrical connector assembly |
| KR101313395B1 (ko) | 2005-09-12 | 2013-10-02 | 액테리온 파마슈티칼 리미티드 | 피리미딘-설파마이드를 함유하는 안정한 제약학적 조성물 |
| AR062501A1 (es) | 2006-08-29 | 2008-11-12 | Actelion Pharmaceuticals Ltd | Composiciones terapeuticas |
| KR20100132489A (ko) | 2008-02-20 | 2010-12-17 | 액테리온 파마슈티칼 리미티드 | 난소암을 치료하기 위하여 파클리탁셀을 포함하는 조합 |
| HUE047767T2 (hu) | 2008-08-13 | 2020-05-28 | Actelion Pharmaceuticals Ltd | Macitentánt tartalmazó terápiás készítmények |
| TW201309298A (zh) | 2011-02-04 | 2013-03-01 | Actelion Pharmaceuticals Ltd | 治療惡性神經膠質瘤之醫藥組合物 |
-
2006
- 2006-09-11 KR KR1020087008450A patent/KR101313395B1/ko active Active
- 2006-09-11 WO PCT/IB2006/053210 patent/WO2007031933A2/en not_active Ceased
- 2006-09-11 SI SI200631471T patent/SI1928409T1/sl unknown
- 2006-09-11 CA CA2621273A patent/CA2621273C/en active Active
- 2006-09-11 DK DK06809280.8T patent/DK1928409T3/da active
- 2006-09-11 HR HRP20120957TT patent/HRP20120957T1/hr unknown
- 2006-09-11 AU AU2006290309A patent/AU2006290309B2/en active Active
- 2006-09-11 ES ES06809280T patent/ES2393117T3/es active Active
- 2006-09-11 US US12/066,448 patent/US20080233188A1/en not_active Abandoned
- 2006-09-11 JP JP2008529767A patent/JP4955685B2/ja active Active
- 2006-09-11 EP EP06809280A patent/EP1928409B1/en active Active
- 2006-09-11 PT PT06809280T patent/PT1928409E/pt unknown
- 2006-09-11 CN CN2006800333751A patent/CN101262847B/zh active Active
- 2006-09-11 EP EP10009910A patent/EP2292209A3/en not_active Withdrawn
- 2006-09-11 PL PL06809280T patent/PL1928409T3/pl unknown
- 2006-09-11 BR BRPI0615898A patent/BRPI0615898B8/pt active IP Right Grant
- 2006-09-11 RU RU2008113869/15A patent/RU2424805C2/ru active
- 2006-09-11 MY MYPI20080524 patent/MY151003A/en unknown
- 2006-09-11 NZ NZ567188A patent/NZ567188A/en unknown
- 2006-09-12 TW TW095133695A patent/TWI323661B/zh active
-
2008
- 2008-03-11 IL IL190072A patent/IL190072A/en active IP Right Grant
- 2008-04-03 ZA ZA200802947A patent/ZA200802947B/xx unknown
- 2008-04-09 NO NO20081724A patent/NO341325B1/no unknown
-
2009
- 2009-02-18 US US12/388,142 patent/US8367685B2/en active Active
- 2009-05-01 JP JP2009112258A patent/JP5054061B2/ja active Active
-
2012
- 2012-11-21 CY CY20121101126T patent/CY1113395T1/el unknown
-
2013
- 2013-01-08 US US13/736,699 patent/US9265762B2/en active Active
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2016
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2020
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