HRP20120644T1 - Farmaceutski pripravak - Google Patents
Farmaceutski pripravak Download PDFInfo
- Publication number
- HRP20120644T1 HRP20120644T1 HRP20120644AT HRP20120644T HRP20120644T1 HR P20120644 T1 HRP20120644 T1 HR P20120644T1 HR P20120644A T HRP20120644A T HR P20120644AT HR P20120644 T HRP20120644 T HR P20120644T HR P20120644 T1 HRP20120644 T1 HR P20120644T1
- Authority
- HR
- Croatia
- Prior art keywords
- pharmaceutical preparation
- pharmaceutical composition
- agent
- preparation according
- group containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 4
- 150000002337 glycosamines Chemical class 0.000 claims abstract 3
- ALLWOAVDORUJLA-UHFFFAOYSA-N Rebamipida Chemical compound C=1C(=O)NC2=CC=CC=C2C=1CC(C(=O)O)NC(=O)C1=CC=C(Cl)C=C1 ALLWOAVDORUJLA-UHFFFAOYSA-N 0.000 claims abstract 2
- 150000001767 cationic compounds Chemical class 0.000 claims abstract 2
- 229910001411 inorganic cation Inorganic materials 0.000 claims abstract 2
- 229950004535 rebamipide Drugs 0.000 claims abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 1
- MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 claims 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 claims 1
- MSWZFWKMSRAUBD-QZABAPFNSA-N beta-D-glucosamine Chemical compound N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-QZABAPFNSA-N 0.000 claims 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims 1
- 239000004327 boric acid Substances 0.000 claims 1
- 229960003511 macrogol Drugs 0.000 claims 1
- 229960003194 meglumine Drugs 0.000 claims 1
- 239000003002 pH adjusting agent Substances 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 239000006172 buffering agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008160084 | 2008-06-19 | ||
| PCT/JP2009/061553 WO2009154304A2 (en) | 2008-06-19 | 2009-06-18 | A pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120644T1 true HRP20120644T1 (hr) | 2012-08-31 |
Family
ID=41334556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20120644AT HRP20120644T1 (hr) | 2008-06-19 | 2012-08-08 | Farmaceutski pripravak |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20110124682A1 (da) |
| EP (1) | EP2285413B1 (da) |
| JP (1) | JP5441934B2 (da) |
| KR (1) | KR20110027786A (da) |
| CN (1) | CN102099056B (da) |
| AR (1) | AR072212A1 (da) |
| AU (1) | AU2009261101B2 (da) |
| BR (1) | BRPI0915427A2 (da) |
| CA (1) | CA2725487A1 (da) |
| CO (1) | CO6280502A2 (da) |
| CY (1) | CY1113214T1 (da) |
| DK (1) | DK2285413T3 (da) |
| ES (1) | ES2389583T3 (da) |
| HK (1) | HK1149496A1 (da) |
| HR (1) | HRP20120644T1 (da) |
| IL (1) | IL209329A (da) |
| MX (1) | MX2010013733A (da) |
| MY (1) | MY150558A (da) |
| NZ (1) | NZ589517A (da) |
| PL (1) | PL2285413T3 (da) |
| PT (1) | PT2285413E (da) |
| RU (1) | RU2538694C2 (da) |
| SI (1) | SI2285413T1 (da) |
| TW (1) | TWI495634B (da) |
| UA (1) | UA100164C2 (da) |
| WO (1) | WO2009154304A2 (da) |
| ZA (1) | ZA201008584B (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201322982A (zh) * | 2011-11-01 | 2013-06-16 | Otsuka Pharma Co Ltd | 用於治療前眼疾病之藥劑，該藥劑包含瑞巴派特及眼淚保持劑 |
| TW201417814A (zh) * | 2012-09-28 | 2014-05-16 | Otsuka Pharma Co Ltd | 包括瑞巴派特之醫藥組成物 |
| KR101692578B1 (ko) | 2013-04-18 | 2017-01-03 | 삼진제약주식회사 | 레바미피드 또는 이의 전구체를 포함하는 안구건조증의 예방 또는 치료를 위한 경구용 약제학적 조성물 |
| WO2015034008A1 (ja) * | 2013-09-05 | 2015-03-12 | 大塚製薬株式会社 | レバミピドの局所止血用途 |
| JP6854587B2 (ja) * | 2015-04-17 | 2021-04-07 | ロート製薬株式会社 | 医薬製剤 |
| KR20170039347A (ko) * | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
| KR102307958B1 (ko) | 2015-10-01 | 2021-10-05 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
| US11324829B2 (en) | 2016-03-14 | 2022-05-10 | Santen Pharmaceutical Co., Ltd. | Antiseptic agent comprising meglumine or salt thereof |
| CN106491530B (zh) * | 2016-12-13 | 2019-11-29 | 湖北远大天天明制药有限公司 | 一种眼用药物组合物 |
| KR101840256B1 (ko) * | 2017-09-21 | 2018-03-21 | 대우제약 주식회사 | 레바미피드를 함유하는 새로운 안구건조증 치료용 점안 조성물 및 이의 가용화 및 안정화 방법 |
| KR101923519B1 (ko) * | 2018-06-26 | 2019-02-27 | 대우제약 주식회사 | 레바미피드를 함유하는 안구 건조증 치료용 수용성 다회용 점안제 조성물 및 이의 가용화 및 안정화 방법 |
| KR20200019451A (ko) | 2018-08-14 | 2020-02-24 | 대우제약 주식회사 | 레바미피드를 함유하는 안구 건조증 치료용 수용성 다회용 점안제 조성물 및 이의 가용화 및 안정화 방법 |
| JP6744952B2 (ja) * | 2019-05-28 | 2020-08-19 | ロート製薬株式会社 | 眼科用組成物 |
| KR102615076B1 (ko) | 2021-07-14 | 2023-12-19 | 대우제약 주식회사 | 안정한 레바미피드 점안제의 대용량 제조 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3093661B2 (ja) * | 1995-10-12 | 2000-10-03 | 大塚製薬株式会社 | 眼疾患治療剤 |
| AR004214A1 (es) * | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
| AU1054301A (en) * | 1999-11-11 | 2001-06-06 | Takeda Chemical Industries Ltd. | Nasal drops containing fused pyridazine derivatives |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| TWI363626B (en) * | 2004-11-15 | 2012-05-11 | Otsuka Pharma Co Ltd | Aqueous ophthalmic suspension of crystalline rebamipide |
| TWI415629B (zh) * | 2006-10-26 | 2013-11-21 | Otsuka Pharma Co Ltd | 含有瑞巴匹特之水性醫藥懸浮物及其製造方法 |
-
2009
- 2009-06-18 CA CA2725487A patent/CA2725487A1/en not_active Abandoned
- 2009-06-18 US US12/999,967 patent/US20110124682A1/en not_active Abandoned
- 2009-06-18 DK DK09766752.1T patent/DK2285413T3/da active
- 2009-06-18 JP JP2010549965A patent/JP5441934B2/ja not_active Expired - Fee Related
- 2009-06-18 KR KR1020117001269A patent/KR20110027786A/ko active IP Right Grant
- 2009-06-18 SI SI200930313T patent/SI2285413T1/sl unknown
- 2009-06-18 WO PCT/JP2009/061553 patent/WO2009154304A2/en active Application Filing
- 2009-06-18 TW TW098120372A patent/TWI495634B/zh not_active IP Right Cessation
- 2009-06-18 EP EP09766752A patent/EP2285413B1/en not_active Not-in-force
- 2009-06-18 CN CN200980122871.8A patent/CN102099056B/zh not_active Expired - Fee Related
- 2009-06-18 MY MYPI20105480 patent/MY150558A/en unknown
- 2009-06-18 PL PL09766752T patent/PL2285413T3/pl unknown
- 2009-06-18 ES ES09766752T patent/ES2389583T3/es active Active
- 2009-06-18 BR BRPI0915427A patent/BRPI0915427A2/pt not_active IP Right Cessation
- 2009-06-18 RU RU2011101713/15A patent/RU2538694C2/ru not_active IP Right Cessation
- 2009-06-18 PT PT09766752T patent/PT2285413E/pt unknown
- 2009-06-18 AU AU2009261101A patent/AU2009261101B2/en not_active Ceased
- 2009-06-18 MX MX2010013733A patent/MX2010013733A/es active IP Right Grant
- 2009-06-18 NZ NZ589517A patent/NZ589517A/xx not_active IP Right Cessation
- 2009-06-18 UA UAA201100566A patent/UA100164C2/ru unknown
- 2009-06-19 AR ARP090102253A patent/AR072212A1/es unknown
-
2010
- 2010-11-15 IL IL209329A patent/IL209329A/en not_active IP Right Cessation
- 2010-11-30 ZA ZA2010/08584A patent/ZA201008584B/en unknown
-
2011
- 2011-01-19 CO CO11005099A patent/CO6280502A2/es not_active Application Discontinuation
- 2011-04-14 HK HK11103774.3A patent/HK1149496A1/xx not_active IP Right Cessation
-
2012
- 2012-08-08 HR HRP20120644AT patent/HRP20120644T1/hr unknown
- 2012-10-16 CY CY20121100960T patent/CY1113214T1/el unknown
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