BR112014025711A2 - composto, medicamento, e, uso de um composto - Google Patents

composto, medicamento, e, uso de um composto

Info

Publication number
BR112014025711A2
BR112014025711A2 BR112014025711A BR112014025711A BR112014025711A2 BR 112014025711 A2 BR112014025711 A2 BR 112014025711A2 BR 112014025711 A BR112014025711 A BR 112014025711A BR 112014025711 A BR112014025711 A BR 112014025711A BR 112014025711 A2 BR112014025711 A2 BR 112014025711A2
Authority
BR
Brazil
Prior art keywords
compound
medicine
present
schizophrenia
prophylaxis
Prior art date
Application number
BR112014025711A
Other languages
English (en)
Other versions
BR112014025711A8 (pt
Inventor
Nomura Izumi
Kawasaki Masanori
Nakamura Shinji
Mikami Satoshi
Sasaki Shigekazu
Taniguchi Takahiko
Ashizawa Tomoko
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of BR112014025711A2 publication Critical patent/BR112014025711A2/pt
Publication of BR112014025711A8 publication Critical patent/BR112014025711A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

1 / 1 resumo “composto, medicamento, e, uso de um composto” a presente invenã§ã£o proporciona um composto possuindo uma aã§ã£o inibidora seletiva de pde2a, que ã© ãºtil como um agente para a profilaxia ou tratamento de esquizofrenia, mal de alzheimer e similares. a presente invenã§ã£o ã© um composto representado pela fã³rmula (1): em que cada sã­mbolo ã© tal como foi descrito no relatã³rio descritivo, ou um seu sal.
BR112014025711A 2012-04-25 2013-04-24 composto, medicamento, e, uso de um composto BR112014025711A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012100374 2012-04-25
JP2012283470 2012-12-26
PCT/JP2013/062140 WO2013161913A1 (ja) 2012-04-25 2013-04-24 含窒素複素環化合物

Publications (2)

Publication Number Publication Date
BR112014025711A2 true BR112014025711A2 (pt) 2017-07-04
BR112014025711A8 BR112014025711A8 (pt) 2018-01-16

Family

ID=49483221

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014025711A BR112014025711A8 (pt) 2012-04-25 2013-04-24 composto, medicamento, e, uso de um composto

Country Status (25)

Country Link
US (2) US9469637B2 (pt)
EP (1) EP2848618B1 (pt)
JP (1) JP6157455B2 (pt)
KR (1) KR20150005936A (pt)
AU (1) AU2013253516B2 (pt)
BR (1) BR112014025711A8 (pt)
CA (1) CA2869730A1 (pt)
CL (1) CL2014002880A1 (pt)
CO (1) CO7141410A2 (pt)
CR (1) CR20140537A (pt)
DO (1) DOP2014000243A (pt)
EA (1) EA029892B1 (pt)
GE (1) GEP20166554B (pt)
HK (1) HK1203500A1 (pt)
IL (1) IL235048B (pt)
MX (1) MX361539B (pt)
MY (1) MY173949A (pt)
NZ (1) NZ631258A (pt)
PE (1) PE20142258A1 (pt)
PH (1) PH12014502396B1 (pt)
SG (1) SG11201406552UA (pt)
TN (1) TN2014000416A1 (pt)
UA (1) UA115057C2 (pt)
WO (1) WO2013161913A1 (pt)
ZA (1) ZA201408644B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
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EP2848618B1 (en) 2012-04-25 2018-03-14 Takeda Pharmaceutical Company Limited Nitrogenated heterocyclic compound
JP6205356B2 (ja) 2012-07-13 2017-09-27 武田薬品工業株式会社 複素環化合物
JP6280912B2 (ja) 2013-03-14 2018-02-14 武田薬品工業株式会社 複素環化合物
US10053468B2 (en) 2013-07-03 2018-08-21 Takeda Pharmaceutical Company Limited Heterocyclic compound
US10472376B2 (en) 2013-07-03 2019-11-12 Takeda Pharmaceutical Company Limited Amide compound
JPWO2015012328A1 (ja) * 2013-07-24 2017-03-02 武田薬品工業株式会社 複素環化合物
US20160264536A1 (en) * 2013-10-23 2016-09-15 Takeda Pharmaceutical Company Limited Heterocyclic compound
US9815796B2 (en) 2013-12-23 2017-11-14 Merck Sharp & Dohme Corp. Pyrimidone carboxamide compounds as PDE2 inhibitors
JP2017114764A (ja) * 2014-04-25 2017-06-29 武田薬品工業株式会社 片頭痛治療剤
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EP3291817B1 (en) 2015-05-05 2019-10-02 Merck Sharp & Dohme Corp. Heteroaryl-pyrimidinone compounds as pde2 inhibitors
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Also Published As

Publication number Publication date
CN104245698A (zh) 2014-12-24
KR20150005936A (ko) 2015-01-15
IL235048B (en) 2018-11-29
US10017508B2 (en) 2018-07-10
JP6157455B2 (ja) 2017-07-05
CR20140537A (es) 2015-02-03
US20170129887A1 (en) 2017-05-11
MX361539B (es) 2018-12-10
TN2014000416A1 (en) 2016-03-30
DOP2014000243A (es) 2014-12-31
NZ631258A (en) 2016-11-25
UA115057C2 (uk) 2017-09-11
EA201491936A1 (ru) 2015-03-31
MY173949A (en) 2020-02-28
CO7141410A2 (es) 2014-12-12
WO2013161913A1 (ja) 2013-10-31
PH12014502396A1 (en) 2014-12-22
PE20142258A1 (es) 2015-01-15
ZA201408644B (en) 2016-02-24
EP2848618A1 (en) 2015-03-18
AU2013253516A1 (en) 2014-12-18
US9469637B2 (en) 2016-10-18
MX2014013011A (es) 2015-01-12
PH12014502396B1 (en) 2014-12-22
AU2013253516B2 (en) 2017-10-12
JPWO2013161913A1 (ja) 2015-12-24
CA2869730A1 (en) 2013-10-31
US20150105373A1 (en) 2015-04-16
HK1203500A1 (en) 2015-10-30
GEP20166554B (en) 2016-10-10
CL2014002880A1 (es) 2015-02-06
AU2013253516A2 (en) 2015-04-02
SG11201406552UA (en) 2014-11-27
EP2848618A4 (en) 2015-11-11
EP2848618B1 (en) 2018-03-14
EA029892B1 (ru) 2018-05-31
BR112014025711A8 (pt) 2018-01-16

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