CO6280502A2 - Una composicion farmaceutica - Google Patents
Una composicion farmaceuticaInfo
- Publication number
- CO6280502A2 CO6280502A2 CO11005099A CO11005099A CO6280502A2 CO 6280502 A2 CO6280502 A2 CO 6280502A2 CO 11005099 A CO11005099 A CO 11005099A CO 11005099 A CO11005099 A CO 11005099A CO 6280502 A2 CO6280502 A2 CO 6280502A2
- Authority
- CO
- Colombia
- Prior art keywords
- pharmaceutical composition
- rebamipide
- present
- keratoconjunctive
- redispersed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un objeto de la presente invención es proporcionar una composición farmacéutica que contiene rebamipida, la cual no necesita redispersarse, tiene una suficiente transparencia y exhibe pH neutro a ácido para no dañar la queratoconjuntiva de un paciente que sufre de ojo seco; la presente composición farmacéutica comprende (1) rebamipida, (2) un aminoazúcar, y (3) un agente regulador de pH, que no tiene catión inorgánico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008160084 | 2008-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6280502A2 true CO6280502A2 (es) | 2011-05-20 |
Family
ID=41334556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO11005099A CO6280502A2 (es) | 2008-06-19 | 2011-01-19 | Una composicion farmaceutica |
Country Status (27)
Country | Link |
---|---|
US (1) | US20110124682A1 (es) |
EP (1) | EP2285413B1 (es) |
JP (1) | JP5441934B2 (es) |
KR (1) | KR20110027786A (es) |
CN (1) | CN102099056B (es) |
AR (1) | AR072212A1 (es) |
AU (1) | AU2009261101B2 (es) |
BR (1) | BRPI0915427A2 (es) |
CA (1) | CA2725487A1 (es) |
CO (1) | CO6280502A2 (es) |
CY (1) | CY1113214T1 (es) |
DK (1) | DK2285413T3 (es) |
ES (1) | ES2389583T3 (es) |
HK (1) | HK1149496A1 (es) |
HR (1) | HRP20120644T1 (es) |
IL (1) | IL209329A (es) |
MX (1) | MX2010013733A (es) |
MY (1) | MY150558A (es) |
NZ (1) | NZ589517A (es) |
PL (1) | PL2285413T3 (es) |
PT (1) | PT2285413E (es) |
RU (1) | RU2538694C2 (es) |
SI (1) | SI2285413T1 (es) |
TW (1) | TWI495634B (es) |
UA (1) | UA100164C2 (es) |
WO (1) | WO2009154304A2 (es) |
ZA (1) | ZA201008584B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201322982A (zh) * | 2011-11-01 | 2013-06-16 | Otsuka Pharma Co Ltd | 用於治療前眼疾病之藥劑,該藥劑包含瑞巴派特及眼淚保持劑 |
TW201417814A (zh) * | 2012-09-28 | 2014-05-16 | Otsuka Pharma Co Ltd | 包括瑞巴派特之醫藥組成物 |
KR101692578B1 (ko) | 2013-04-18 | 2017-01-03 | 삼진제약주식회사 | 레바미피드 또는 이의 전구체를 포함하는 안구건조증의 예방 또는 치료를 위한 경구용 약제학적 조성물 |
WO2015034008A1 (ja) * | 2013-09-05 | 2015-03-12 | 大塚製薬株式会社 | レバミピドの局所止血用途 |
JP6854587B2 (ja) * | 2015-04-17 | 2021-04-07 | ロート製薬株式会社 | 医薬製剤 |
KR20170039347A (ko) * | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
KR102307958B1 (ko) | 2015-10-01 | 2021-10-05 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
WO2017159585A1 (ja) * | 2016-03-14 | 2017-09-21 | 参天製薬株式会社 | メグルミン又はその塩からなる防腐剤 |
CN106491530B (zh) * | 2016-12-13 | 2019-11-29 | 湖北远大天天明制药有限公司 | 一种眼用药物组合物 |
KR101840256B1 (ko) * | 2017-09-21 | 2018-03-21 | 대우제약 주식회사 | 레바미피드를 함유하는 새로운 안구건조증 치료용 점안 조성물 및 이의 가용화 및 안정화 방법 |
KR101923519B1 (ko) * | 2018-06-26 | 2019-02-27 | 대우제약 주식회사 | 레바미피드를 함유하는 안구 건조증 치료용 수용성 다회용 점안제 조성물 및 이의 가용화 및 안정화 방법 |
KR20200019451A (ko) | 2018-08-14 | 2020-02-24 | 대우제약 주식회사 | 레바미피드를 함유하는 안구 건조증 치료용 수용성 다회용 점안제 조성물 및 이의 가용화 및 안정화 방법 |
JP6744952B2 (ja) * | 2019-05-28 | 2020-08-19 | ロート製薬株式会社 | 眼科用組成物 |
KR102615076B1 (ko) | 2021-07-14 | 2023-12-19 | 대우제약 주식회사 | 안정한 레바미피드 점안제의 대용량 제조 방법 |
KR102659338B1 (ko) | 2023-05-18 | 2024-04-19 | 국제약품 주식회사 | 안구건조증 치료용 약제학적 조성물 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR004214A1 (es) * | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
JP3093661B2 (ja) * | 1995-10-12 | 2000-10-03 | 大塚製薬株式会社 | 眼疾患治療剤 |
KR20020050275A (ko) * | 1999-11-11 | 2002-06-26 | 다케다 야쿠힌 고교 가부시키가이샤 | 융합 피리다진 유도체를 함유하는 점비제 |
TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
TWI363626B (en) * | 2004-11-15 | 2012-05-11 | Otsuka Pharma Co Ltd | Aqueous ophthalmic suspension of crystalline rebamipide |
TWI415629B (zh) * | 2006-10-26 | 2013-11-21 | Otsuka Pharma Co Ltd | 含有瑞巴匹特之水性醫藥懸浮物及其製造方法 |
-
2009
- 2009-06-18 CA CA2725487A patent/CA2725487A1/en not_active Abandoned
- 2009-06-18 JP JP2010549965A patent/JP5441934B2/ja not_active Expired - Fee Related
- 2009-06-18 CN CN200980122871.8A patent/CN102099056B/zh not_active Expired - Fee Related
- 2009-06-18 DK DK09766752.1T patent/DK2285413T3/da active
- 2009-06-18 PL PL09766752T patent/PL2285413T3/pl unknown
- 2009-06-18 PT PT09766752T patent/PT2285413E/pt unknown
- 2009-06-18 KR KR1020117001269A patent/KR20110027786A/ko active IP Right Grant
- 2009-06-18 SI SI200930313T patent/SI2285413T1/sl unknown
- 2009-06-18 MX MX2010013733A patent/MX2010013733A/es active IP Right Grant
- 2009-06-18 TW TW098120372A patent/TWI495634B/zh not_active IP Right Cessation
- 2009-06-18 US US12/999,967 patent/US20110124682A1/en not_active Abandoned
- 2009-06-18 AU AU2009261101A patent/AU2009261101B2/en not_active Ceased
- 2009-06-18 EP EP09766752A patent/EP2285413B1/en not_active Not-in-force
- 2009-06-18 MY MYPI20105480 patent/MY150558A/en unknown
- 2009-06-18 UA UAA201100566A patent/UA100164C2/ru unknown
- 2009-06-18 BR BRPI0915427A patent/BRPI0915427A2/pt not_active IP Right Cessation
- 2009-06-18 RU RU2011101713/15A patent/RU2538694C2/ru not_active IP Right Cessation
- 2009-06-18 WO PCT/JP2009/061553 patent/WO2009154304A2/en active Application Filing
- 2009-06-18 ES ES09766752T patent/ES2389583T3/es active Active
- 2009-06-18 NZ NZ589517A patent/NZ589517A/xx not_active IP Right Cessation
- 2009-06-19 AR ARP090102253A patent/AR072212A1/es unknown
-
2010
- 2010-11-15 IL IL209329A patent/IL209329A/en not_active IP Right Cessation
- 2010-11-30 ZA ZA2010/08584A patent/ZA201008584B/en unknown
-
2011
- 2011-01-19 CO CO11005099A patent/CO6280502A2/es not_active Application Discontinuation
- 2011-04-14 HK HK11103774.3A patent/HK1149496A1/xx not_active IP Right Cessation
-
2012
- 2012-08-08 HR HRP20120644AT patent/HRP20120644T1/hr unknown
- 2012-10-16 CY CY20121100960T patent/CY1113214T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Application refused |