HRP20110399T1 - Mikrofluidički uređaj i postupak za određivanje vremena koagulacije fluida - Google Patents
Mikrofluidički uređaj i postupak za određivanje vremena koagulacije fluida Download PDFInfo
- Publication number
- HRP20110399T1 HRP20110399T1 HR20110399T HRP20110399T HRP20110399T1 HR P20110399 T1 HRP20110399 T1 HR P20110399T1 HR 20110399 T HR20110399 T HR 20110399T HR P20110399 T HRP20110399 T HR P20110399T HR P20110399 T1 HRP20110399 T1 HR P20110399T1
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- Croatia
- Prior art keywords
- region
- fluid medium
- specified
- microfluidic device
- reagent
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title claims abstract 29
- 238000000034 method Methods 0.000 title claims abstract 8
- 206010053567 Coagulopathies Diseases 0.000 title abstract 2
- 230000035602 clotting Effects 0.000 title abstract 2
- 239000008280 blood Substances 0.000 claims abstract 8
- 210000004369 blood Anatomy 0.000 claims abstract 8
- 238000012544 monitoring process Methods 0.000 claims abstract 4
- 238000004519 manufacturing process Methods 0.000 claims abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 13
- 230000015271 coagulation Effects 0.000 claims 12
- 238000005345 coagulation Methods 0.000 claims 12
- 239000000758 substrate Substances 0.000 claims 7
- 230000003287 optical effect Effects 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 3
- 238000003908 quality control method Methods 0.000 claims 3
- 238000013022 venting Methods 0.000 claims 3
- PGOHTUIFYSHAQG-LJSDBVFPSA-N (2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]hexanoic acid Chemical compound CSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O PGOHTUIFYSHAQG-LJSDBVFPSA-N 0.000 claims 1
- 108010094028 Prothrombin Proteins 0.000 claims 1
- 102100027378 Prothrombin Human genes 0.000 claims 1
- 108010000499 Thromboplastin Proteins 0.000 claims 1
- 102000002262 Thromboplastin Human genes 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 238000012806 monitoring device Methods 0.000 claims 1
- 229940039716 prothrombin Drugs 0.000 claims 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
- Y10T156/10—Methods of surface bonding and/or assembly therefor
- Y10T156/1002—Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina
- Y10T156/1039—Surface deformation only of sandwich or lamina [e.g., embossed panels]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Ecology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Quality & Reliability (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Reciprocating Pumps (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07380258A EP2040073A1 (fr) | 2007-09-20 | 2007-09-20 | Dispositif microfluidique et procédé pour la détermination du temps de coagulation d'un fluide |
| PCT/EP2008/062642 WO2009037361A1 (fr) | 2007-09-20 | 2008-09-22 | Dispositif microfluidique et procédé de détermination du temps de coagulation d'un fluide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20110399T1 true HRP20110399T1 (hr) | 2011-06-30 |
Family
ID=39135160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110399T HRP20110399T1 (hr) | 2007-09-20 | 2011-05-27 | Mikrofluidički uređaj i postupak za određivanje vremena koagulacije fluida |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8961903B2 (fr) |
| EP (3) | EP2040073A1 (fr) |
| JP (2) | JP5579607B2 (fr) |
| KR (2) | KR101439404B1 (fr) |
| CN (2) | CN103143405B (fr) |
| AT (1) | ATE504832T1 (fr) |
| AU (1) | AU2008300501B2 (fr) |
| BR (2) | BRPI0817105B1 (fr) |
| CA (2) | CA2700073C (fr) |
| DE (1) | DE602008006108D1 (fr) |
| DK (1) | DK2201365T3 (fr) |
| ES (1) | ES2364568T3 (fr) |
| HK (1) | HK1181697A1 (fr) |
| HR (1) | HRP20110399T1 (fr) |
| IL (2) | IL204571A (fr) |
| MX (1) | MX2010003037A (fr) |
| NZ (2) | NZ600747A (fr) |
| PL (1) | PL2201365T3 (fr) |
| PT (1) | PT2201365E (fr) |
| RU (2) | RU2477480C2 (fr) |
| SI (1) | SI2201365T1 (fr) |
| WO (1) | WO2009037361A1 (fr) |
| ZA (2) | ZA201001950B (fr) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2040073A1 (fr) | 2007-09-20 | 2009-03-25 | Iline Microsystems, S.L. | Dispositif microfluidique et procédé pour la détermination du temps de coagulation d'un fluide |
| WO2009149257A1 (fr) | 2008-06-04 | 2009-12-10 | The University Of Chicago | Chemistrode : dispositif micro-fluidique à base de cônes et procédé de stimulation et d'échantillonnage avec résolution chimique, spatiale et temporelle élevée |
| WO2010015689A1 (fr) * | 2008-08-06 | 2010-02-11 | Roche Diagnostics Gmbh | Système médical avec lecteur de codes-barres compact pour consommables |
| US20120077260A1 (en) * | 2009-03-30 | 2012-03-29 | Fraunhofer Usa, Inc. | Reservoir-buffered mixers and remote valve switching for microfluidic devices |
| CN102448612B (zh) * | 2009-04-13 | 2014-12-03 | 精密公司 | 微流体临床分析器 |
| JP5816613B2 (ja) * | 2009-04-23 | 2015-11-18 | ダブリン シティ ユニバーシティ | 凝固をモニタするための側方流動分析装置及びその方法 |
| EP2570187A3 (fr) * | 2010-01-24 | 2014-08-13 | Instytut Chemii Fizycznej Polskiej Akademii Nauk | Système de génération et de manipulation automatiques de mélanges liquides |
| KR101851117B1 (ko) | 2010-01-29 | 2018-04-23 | 마이크로닉스 인코포레이티드. | 샘플-투-앤서 마이크로유체 카트리지 |
| JP5628409B2 (ja) * | 2010-03-30 | 2014-11-19 | ツェー アー カズィゾ アーゲーＣａ Ｃａｓｙｓｏ Ａｇ | 試験液の凝固特性を測定するための組成物 |
| JP5592144B2 (ja) * | 2010-04-27 | 2014-09-17 | 日本電信電話株式会社 | 凝固活性測定装置および測定方法 |
| EP2596347B1 (fr) | 2010-07-22 | 2017-09-06 | Hach Company | Analyse d'alcalinité en utiisant un laboratoire-sur-puce |
| EP2490020A1 (fr) * | 2011-02-18 | 2012-08-22 | Koninklijke Philips Electronics N.V. | Puce de mesure, dispositif microfluidique et procédé de fabrication du puce de mesure |
| DE102011004805A1 (de) * | 2011-02-28 | 2012-08-30 | Siemens Aktiengesellschaft | Miniaturisierte magnetische Durchflusszytometrie |
| GB201109203D0 (en) * | 2011-06-01 | 2011-07-13 | Carclo Technical Plastics Ltd | Fluid flow control |
| FI124169B (fi) * | 2011-06-14 | 2014-04-15 | Sandvik Mining & Constr Oy | Menetelmä poraussuunnitelman laatimiseksi |
| WO2013015443A1 (fr) * | 2011-07-28 | 2013-01-31 | 京セラ株式会社 | Biocapteur |
| KR101193566B1 (ko) | 2011-08-10 | 2012-10-22 | 고려대학교 산학협력단 | 마이크로칩 기반 혈소판 복합기능 검사 장치 |
| GB201113992D0 (en) | 2011-08-12 | 2011-09-28 | Molecular Vision Ltd | Device |
| JP5607593B2 (ja) * | 2011-09-05 | 2014-10-15 | 日本電信電話株式会社 | 凝固活性測定装置、測定チップおよび測定方法 |
| JP5592324B2 (ja) * | 2011-09-05 | 2014-09-17 | 日本電信電話株式会社 | 凝固活性測定装置および測定方法 |
| EP2788735B1 (fr) * | 2011-12-06 | 2019-02-06 | Medtronic Inc. | Algorithme de détection de caillot et de protection contre les caillots pour test de temps de coagulation activée |
| EP2805158B8 (fr) | 2012-01-16 | 2020-10-07 | Abram Scientific, Inc. | Procédés et dispositifs pour mesurer les propriétés physiques d'un fluide |
| WO2013135713A1 (fr) * | 2012-03-12 | 2013-09-19 | Biosurfit S.A. | Dispositif d'imagerie d'échantillon liquide et procédé associé |
| US9180449B2 (en) | 2012-06-12 | 2015-11-10 | Hach Company | Mobile water analysis |
| US9709579B2 (en) * | 2012-06-27 | 2017-07-18 | Colorado School Of Mines | Microfluidic flow assay and methods of use |
| US9551699B2 (en) * | 2012-07-16 | 2017-01-24 | Micropoint Bioscience, Inc. | Testing of blood coagulation characteristics |
| CN104704357A (zh) * | 2012-07-30 | 2015-06-10 | 加利福尼亚大学董事会 | 生物分子检测的测试条设计 |
| EA021562B1 (ru) * | 2012-08-15 | 2015-07-30 | Общество С Ограниченной Ответственностью "Гематологическая Корпорация" | Устройство мониторинга пространственного свертывания крови и ее компонентов |
| JP6010434B2 (ja) * | 2012-11-15 | 2016-10-19 | 株式会社オーイーエムシステム | 体液成分分析装置および体液成分分析方法 |
| USD768872S1 (en) | 2012-12-12 | 2016-10-11 | Hach Company | Cuvette for a water analysis instrument |
| HU1200732D0 (hu) * | 2012-12-14 | 2014-06-30 | Haemoglobal Ltd | Egyszer használatos IVD eszköz a véralvadást jellemzõ INR érték otthoni ellenõrzõ méréséhez |
| EP3549674B1 (fr) | 2012-12-21 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Films à faible élasticité pour utilisation micro-fluidique |
| WO2014100725A1 (fr) | 2012-12-21 | 2014-06-26 | Micronics, Inc. | Système portable de détection par fluorescence et cartouche de microanalyse |
| US9297816B1 (en) | 2012-12-21 | 2016-03-29 | University Of South Florida | Devices and methods for measuring blood coagulation |
| US10065186B2 (en) | 2012-12-21 | 2018-09-04 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
| JP6429794B2 (ja) | 2013-01-03 | 2018-11-28 | ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド | バイオミメティック流体プロセスの系および方法 |
| JP6093950B2 (ja) * | 2013-04-26 | 2017-03-15 | 東洋インキＳｃホールディングス株式会社 | 液体分析部材用粘着シートおよび液体分析部材 |
| JP6484222B2 (ja) | 2013-05-07 | 2019-03-13 | マイクロニクス， インコーポレイテッド | 核酸の調製および分析のためのデバイス |
| JP6472788B2 (ja) | 2013-05-07 | 2019-02-20 | マイクロニクス， インコーポレイテッド | 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法 |
| EP2994750B1 (fr) | 2013-05-07 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Dispositifs microfluidiques et méthodes de séparation du sérum et de compatibilité croisée du sang |
| WO2014183886A1 (fr) | 2013-05-14 | 2014-11-20 | Struszym, S.L. | Bandelettes d'essai pour déterminer l'activité des facteurs de coagulation |
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