HRP20100610T1 - Nova fsh glikozilacijska varijanta d3n - Google Patents
Nova fsh glikozilacijska varijanta d3n Download PDFInfo
- Publication number
- HRP20100610T1 HRP20100610T1 HR20100610T HRP20100610T HRP20100610T1 HR P20100610 T1 HRP20100610 T1 HR P20100610T1 HR 20100610 T HR20100610 T HR 20100610T HR P20100610 T HRP20100610 T HR P20100610T HR P20100610 T1 HRP20100610 T1 HR P20100610T1
- Authority
- HR
- Croatia
- Prior art keywords
- seq
- amino acid
- acid sequence
- nucleic acid
- vector
- Prior art date
Links
- 230000013595 glycosylation Effects 0.000 title 1
- 238000006206 glycosylation reaction Methods 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 claims 10
- 108020004707 nucleic acids Proteins 0.000 claims 10
- 150000007523 nucleic acids Chemical class 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 8
- 239000013598 vector Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 4
- 239000000825 pharmaceutical preparation Substances 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 206010033266 Ovarian Hyperstimulation Syndrome Diseases 0.000 claims 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N aspartic acid group Chemical group N[C@@H](CC(=O)O)C(=O)O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000001279 glycosylating effect Effects 0.000 claims 1
- 208000021267 infertility disease Diseases 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Pregnancy & Childbirth (AREA)
- Physics & Mathematics (AREA)
- Gynecology & Obstetrics (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75948606P | 2006-01-17 | 2006-01-17 | |
| PCT/US2007/001004 WO2007084441A2 (en) | 2006-01-17 | 2007-01-16 | Novel fsh glycosylation variant d3n |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100610T1 true HRP20100610T1 (hr) | 2010-12-31 |
Family
ID=38163618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100610T HRP20100610T1 (hr) | 2006-01-17 | 2010-11-11 | Nova fsh glikozilacijska varijanta d3n |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7956034B2 (el) |
| EP (1) | EP1981908B1 (el) |
| JP (1) | JP2009523445A (el) |
| KR (1) | KR20080094697A (el) |
| CN (1) | CN101370825B (el) |
| AR (1) | AR059054A1 (el) |
| AT (1) | ATE487738T1 (el) |
| AU (1) | AU2007207697B2 (el) |
| BR (1) | BRPI0706628A2 (el) |
| CA (1) | CA2633844A1 (el) |
| CY (1) | CY1110953T1 (el) |
| DE (1) | DE602007010425D1 (el) |
| DK (1) | DK1981908T3 (el) |
| EA (1) | EA013974B1 (el) |
| HR (1) | HRP20100610T1 (el) |
| IL (1) | IL192547A (el) |
| PL (1) | PL1981908T3 (el) |
| PT (1) | PT1981908E (el) |
| RS (1) | RS51792B (el) |
| SI (1) | SI1981908T1 (el) |
| WO (1) | WO2007084441A2 (el) |
| ZA (1) | ZA200805194B (el) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1917276T1 (en) * | 2005-08-26 | 2018-05-31 | Ares Trading S.A. | PROCEDURE FOR PREPARATION OF GLYCOSYLATED INTERFERONE BETA |
| US8604175B2 (en) * | 2005-12-09 | 2013-12-10 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
| WO2008010840A2 (en) * | 2005-12-22 | 2008-01-24 | Laboratoires Serono S.A. | Fsh mutants |
| CA2702448A1 (en) * | 2007-10-22 | 2009-04-30 | Merck Serono S.A. | Method for purifying fc-fusion proteins |
| EP2203465A1 (en) * | 2007-10-22 | 2010-07-07 | Merck Serono S.A. | Method for purifying an fc-containing protein |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI0996629T1 (sl) * | 1997-06-25 | 2006-12-31 | Applied Research Systems | Analogi glikoproteinskega hormona povezanega z disulfidi, priprava in uporaba |
| WO2001058493A1 (en) | 2000-02-11 | 2001-08-16 | Maxygen Aps | Conjugates of follicle stimulating hormones |
| ES2389835T3 (es) * | 2001-10-22 | 2012-11-02 | Merck Serono Sa | Glicoproteínas mutantes |
| UA88879C2 (en) * | 2003-09-02 | 2009-12-10 | Эплайд Рисерч Системз Эрс Холдинг Н.В. | Fsh glycosylation mutant |
| US8604175B2 (en) * | 2005-12-09 | 2013-12-10 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
-
2007
- 2007-01-16 EA EA200870177A patent/EA013974B1/ru not_active IP Right Cessation
- 2007-01-16 AT AT07716617T patent/ATE487738T1/de active
- 2007-01-16 ZA ZA200805194A patent/ZA200805194B/xx unknown
- 2007-01-16 RS RS20100568A patent/RS51792B/en unknown
- 2007-01-16 WO PCT/US2007/001004 patent/WO2007084441A2/en active Application Filing
- 2007-01-16 SI SI200730438T patent/SI1981908T1/sl unknown
- 2007-01-16 PL PL07716617T patent/PL1981908T3/pl unknown
- 2007-01-16 PT PT07716617T patent/PT1981908E/pt unknown
- 2007-01-16 US US12/158,539 patent/US7956034B2/en not_active Expired - Fee Related
- 2007-01-16 EP EP07716617A patent/EP1981908B1/en active Active
- 2007-01-16 AU AU2007207697A patent/AU2007207697B2/en not_active Ceased
- 2007-01-16 JP JP2008551305A patent/JP2009523445A/ja active Pending
- 2007-01-16 KR KR1020087020053A patent/KR20080094697A/ko not_active Application Discontinuation
- 2007-01-16 BR BRPI0706628-7A patent/BRPI0706628A2/pt not_active IP Right Cessation
- 2007-01-16 CN CN2007800030734A patent/CN101370825B/zh not_active Expired - Fee Related
- 2007-01-16 DK DK07716617.1T patent/DK1981908T3/da active
- 2007-01-16 DE DE602007010425T patent/DE602007010425D1/de active Active
- 2007-01-16 CA CA002633844A patent/CA2633844A1/en not_active Abandoned
- 2007-01-17 AR ARP070100200A patent/AR059054A1/es not_active Application Discontinuation
-
2008
- 2008-06-30 IL IL192547A patent/IL192547A/en not_active IP Right Cessation
-
2010
- 2010-11-11 HR HR20100610T patent/HRP20100610T1/hr unknown
- 2010-11-25 CY CY20101101080T patent/CY1110953T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007084441A3 (en) | 2007-09-07 |
| CY1110953T1 (el) | 2015-06-11 |
| EP1981908B1 (en) | 2010-11-10 |
| AU2007207697B2 (en) | 2012-01-19 |
| IL192547A0 (en) | 2009-02-11 |
| AR059054A1 (es) | 2008-03-12 |
| CN101370825A (zh) | 2009-02-18 |
| EA013974B1 (ru) | 2010-08-30 |
| EP1981908A2 (en) | 2008-10-22 |
| KR20080094697A (ko) | 2008-10-23 |
| US20080280832A1 (en) | 2008-11-13 |
| PT1981908E (pt) | 2010-11-23 |
| DK1981908T3 (da) | 2010-12-13 |
| CA2633844A1 (en) | 2007-07-26 |
| DE602007010425D1 (de) | 2010-12-23 |
| WO2007084441A2 (en) | 2007-07-26 |
| AU2007207697A1 (en) | 2007-07-26 |
| US7956034B2 (en) | 2011-06-07 |
| BRPI0706628A2 (pt) | 2011-04-05 |
| PL1981908T3 (pl) | 2011-04-29 |
| CN101370825B (zh) | 2012-10-10 |
| IL192547A (en) | 2012-04-30 |
| SI1981908T1 (sl) | 2011-01-31 |
| JP2009523445A (ja) | 2009-06-25 |
| AU2007207697A2 (en) | 2008-07-31 |
| ZA200805194B (en) | 2009-10-28 |
| RS51792B (en) | 2011-12-31 |
| ATE487738T1 (de) | 2010-11-15 |
| EA200870177A1 (ru) | 2009-02-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20100610T1 (hr) | Nova fsh glikozilacijska varijanta d3n | |
| HRP20201185T1 (hr) | Gdf zamke | |
| Bousfield et al. | Structural features of mammalian gonadotropins | |
| WO2006076902A3 (de) | Rekombinante expression von proteinen in einer disulfidverbrückten, zweikettigen form | |
| PE20230409A1 (es) | Composiciones alimenticias con alto contenido en proteinas | |
| IL179617A0 (en) | Method of stabilizing proteins | |
| AR079338A1 (es) | Variantes de proteasa de bacillus y acidos nucleicos que codifican dichas variantes | |
| HRP20110430T1 (hr) | Fsh glikozilacijski mutant | |
| NZ514951A (en) | Recombinant protein production in a cultured human cell | |
| NZ570553A (en) | Immunogenic peptide sequences from influenza A and B and uses thereof for vaccines | |
| PE20100253A1 (es) | Mutantes de fgf21 | |
| MX362028B (es) | Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos. | |
| PE20120358A1 (es) | Mutantes fgf21 y usos de los mismos | |
| BRPI0516176A (pt) | polipeptìdeo, dna, microorganismo, e, processo para produzir l-arginina, l-ornitina ou l-citrulina | |
| CO6270336A2 (es) | Composiciones pepticidas que comprenden uno o mas polipetidos | |
| WO2009004054A3 (en) | A cxc chemokine receptor 4 (cxcr4) antagonistic polypeptide | |
| AR070716A1 (es) | Metodos para modificar el punto isoelectrico de anticuerpos mediante la sustitucion de aminoacidos en la region de determinacion de la complementariedad (cdr) | |
| BRPI0815578B8 (pt) | peptídeos, agentes farmacêuticos compreendendo os mesmos, métodos in vitro para induzir uma célula apresentadora de antígeno, usos dos referidos peptídeos, e vacina | |
| AR040446A1 (es) | Defensinas de plantas | |
| AR040293A1 (es) | Produccion de peptidos y proteinas por acumulacion de cuerpos proteicos derivados de reticulo endoplasmico en plantas | |
| ATE449790T1 (de) | Rekombinante gelatinepartikel für die zelladhäsion | |
| BRPI0410562A (pt) | molécula recombinante e veìculo para expressão, liberação e purificação de polipeptìdeos alvo | |
| CO2023000048A2 (es) | Conjugados de citoquina | |
| NZ594481A (en) | Truncated cystine-knot proteins | |
| ATE386054T1 (de) | Glycosylierte humane interferon alpha isoform |