ATE386054T1 - Glycosylierte humane interferon alpha isoform - Google Patents
Glycosylierte humane interferon alpha isoformInfo
- Publication number
- ATE386054T1 ATE386054T1 AT03791472T AT03791472T ATE386054T1 AT E386054 T1 ATE386054 T1 AT E386054T1 AT 03791472 T AT03791472 T AT 03791472T AT 03791472 T AT03791472 T AT 03791472T AT E386054 T1 ATE386054 T1 AT E386054T1
- Authority
- AT
- Austria
- Prior art keywords
- interferon alpha
- human interferon
- alpha isoform
- glycosylated human
- expression vector
- Prior art date
Links
- 102000006992 Interferon-alpha Human genes 0.000 title abstract 5
- 108010047761 Interferon-alpha Proteins 0.000 title abstract 5
- 108010029485 Protein Isoforms Proteins 0.000 title abstract 5
- 102000001708 Protein Isoforms Human genes 0.000 title abstract 5
- 239000013604 expression vector Substances 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20020052365 | 2002-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE386054T1 true ATE386054T1 (de) | 2008-03-15 |
Family
ID=36241068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03791472T ATE386054T1 (de) | 2002-08-31 | 2003-08-29 | Glycosylierte humane interferon alpha isoform |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7311903B2 (de) |
| EP (1) | EP1549675B1 (de) |
| JP (1) | JP4181543B2 (de) |
| KR (2) | KR20040020817A (de) |
| CN (1) | CN1684979A (de) |
| AT (1) | ATE386054T1 (de) |
| AU (1) | AU2003256125A1 (de) |
| DE (1) | DE60319114T2 (de) |
| WO (1) | WO2004019856A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60332358D1 (de) * | 2002-09-09 | 2010-06-10 | Hanall Pharmaceutical Co Ltd | Protease-resistente modifizierte interferon alpha polypeptide |
| EP1789074A4 (de) * | 2004-08-09 | 2009-08-12 | Alios Biopharma Inc | Synthetische hyperglycosylierte, protease-resistente polypeptid-varianten, orale formulierungen und anwendungsverfahren dafür |
| US7597884B2 (en) * | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| KR100781666B1 (ko) | 2004-11-02 | 2007-12-03 | 신영기 | 인간 인터페론-베타 변이체 |
| AR078117A1 (es) | 2006-06-20 | 2011-10-19 | Protech Pharma S A | Una muteina recombinante del interferon alfa humano glicosilado, un gen que codifica para dicha muteina, un metodo de produccion de dicho gen, un metodo para obtener una celula eucariota productora de dicha muteina, un metodo para producir dicha muteina, un procedimiento para purificar dicha muteina |
| US20080260820A1 (en) * | 2007-04-19 | 2008-10-23 | Gilles Borrelly | Oral dosage formulations of protease-resistant polypeptides |
| US20120225824A1 (en) * | 2008-08-05 | 2012-09-06 | The Trustees Of Columbia University In The City Of New York | Mullerian inhibiting substance (mis) analogues |
| US20110105735A1 (en) * | 2009-10-29 | 2011-05-05 | Heather Desaire | Methods of producing and purifying proteins |
| WO2011075605A2 (en) * | 2009-12-18 | 2011-06-23 | Alios Biopharma, Inc. | Hyperglycosylated interferon variants and methods of use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610830B1 (en) * | 1980-07-01 | 2003-08-26 | Hoffman-La Roche Inc. | Microbial production of mature human leukocyte interferons |
| US4931373A (en) * | 1984-05-25 | 1990-06-05 | Zymogenetics, Inc. | Stable DNA constructs for expression of α-1 antitrypsin |
| US6020465A (en) * | 1993-10-22 | 2000-02-01 | University Of Connecticut | Recombinant avian type i interferon |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| DE69719367T2 (de) * | 1996-12-20 | 2003-10-16 | Takeda Chemical Industries, Ltd. | Verfahren zur herstellung einer zusammensetzung mit verzoegerter abgabe |
| ATE397013T1 (de) * | 1997-09-05 | 2008-06-15 | Altus Pharmaceuticals Inc | Kohlenhydrat-vernetzte glykoproteinkristalle |
-
2003
- 2003-08-29 AU AU2003256125A patent/AU2003256125A1/en not_active Abandoned
- 2003-08-29 DE DE60319114T patent/DE60319114T2/de not_active Expired - Lifetime
- 2003-08-29 JP JP2004532441A patent/JP4181543B2/ja not_active Expired - Fee Related
- 2003-08-29 EP EP03791472A patent/EP1549675B1/de not_active Expired - Lifetime
- 2003-08-29 KR KR1020030060431A patent/KR20040020817A/ko not_active Ceased
- 2003-08-29 CN CNA038232618A patent/CN1684979A/zh active Pending
- 2003-08-29 AT AT03791472T patent/ATE386054T1/de not_active IP Right Cessation
- 2003-08-29 WO PCT/KR2003/001765 patent/WO2004019856A2/en not_active Ceased
- 2003-09-01 KR KR10-2003-0060941A patent/KR100536628B1/ko not_active Expired - Fee Related
- 2003-09-02 US US10/653,350 patent/US7311903B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004019856A2 (en) | 2004-03-11 |
| DE60319114T2 (de) | 2008-12-04 |
| DE60319114D1 (en) | 2008-03-27 |
| AU2003256125A1 (en) | 2004-03-19 |
| EP1549675B1 (de) | 2008-02-13 |
| AU2003256125A8 (en) | 2004-03-19 |
| KR100536628B1 (ko) | 2005-12-14 |
| CN1684979A (zh) | 2005-10-19 |
| KR20040020817A (ko) | 2004-03-09 |
| WO2004019856A3 (en) | 2004-07-29 |
| KR20040020830A (ko) | 2004-03-09 |
| JP2006512058A (ja) | 2006-04-13 |
| EP1549675A4 (de) | 2006-05-31 |
| US20050019871A1 (en) | 2005-01-27 |
| EP1549675A2 (de) | 2005-07-06 |
| US7311903B2 (en) | 2007-12-25 |
| JP4181543B2 (ja) | 2008-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |